@incollection{BraunBouckeBallmann2005, author = {Braun, Carsten and Boucke, Alexander and Ballmann, Josef}, title = {Numerical study of the influence of dynamic pressure and deflected ailerons on the deformation of a high speed wing model}, series = {High performance computing in science and engineering '04. Transactions of the High Performance Computing Center Stuttgart (HLRS) 2004 / Eds.: Egon Krause ...}, booktitle = {High performance computing in science and engineering '04. Transactions of the High Performance Computing Center Stuttgart (HLRS) 2004 / Eds.: Egon Krause ...}, publisher = {Springer}, address = {Berlin}, isbn = {3-540-22943-4}, pages = {225 -- 236}, year = {2005}, language = {en} } @incollection{BallmannBouckeBraun2003, author = {Ballmann, Josef and Boucke, Alexander and Braun, Carsten}, title = {Aeroelastic sensitivity in the transonic regime}, series = {Symposium Transsonicum IV : proceedings of the IUTAM symposium held in G{\"o}ttingen, Germany, 2 - 6 September 2002 / ed. by Helmut Sobieczky. Fluid mechanics and its applications. Vol. 73}, booktitle = {Symposium Transsonicum IV : proceedings of the IUTAM symposium held in G{\"o}ttingen, Germany, 2 - 6 September 2002 / ed. by Helmut Sobieczky. Fluid mechanics and its applications. Vol. 73}, publisher = {Kluwer Academic}, address = {Dordrecht}, isbn = {978-94-010-3998-7}, pages = {225 -- 236}, year = {2003}, language = {en} } @incollection{BraunBouckeHankeetal.2003, author = {Braun, Carsten and Boucke, Alexander and Hanke, M. and Karavas, Alexandros and Ballmann, Josef}, title = {Prediction of the model deformation of a high speed transport aircraft type wing by direct aeroelastic simulation}, series = {High performance computing in science and engineering '03. Transactions of the High Performance Computing Center Stuttgart (HLRS) 2003 / Eds.: Egon Krause ...}, booktitle = {High performance computing in science and engineering '03. Transactions of the High Performance Computing Center Stuttgart (HLRS) 2003 / Eds.: Egon Krause ...}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-540-40850-5}, pages = {331 -- 342}, year = {2003}, language = {de} } @incollection{BrittenBraunHesseetal.2003, author = {Britten, G. and Braun, Carsten and Hesse, M. and Ballmann, Josef}, title = {Computational aeroelasticity with reduced structural models}, series = {Flow modulation and fluid-structure interaction at airplane wings : research results of the Collaborative Research Center SFB 401 at RWTH Aachen, University of Technology, Aachen, Germany / Josef Ballmann (Ed.) Notes on numerical fluid mechanics and multidisciplinary design. Vol. 84}, booktitle = {Flow modulation and fluid-structure interaction at airplane wings : research results of the Collaborative Research Center SFB 401 at RWTH Aachen, University of Technology, Aachen, Germany / Josef Ballmann (Ed.) Notes on numerical fluid mechanics and multidisciplinary design. Vol. 84}, publisher = {Springer}, address = {Berlin}, isbn = {3-540-40209-8}, pages = {275 -- 299}, year = {2003}, language = {en} } @techreport{ReimerWellmerBraunetal.2007, author = {Reimer, Lars and Wellmer, Georg and Braun, Carsten and Ballmann, Josef}, title = {Aerodynamische Simulation und Optimierung in der Flugzeugentwicklung. Teilvorhabenbezeichnung: Aerodynamische Optimierung unter Ber{\"u}cksichtigung von Struktureigenschaften auf der Basis reduzierter Strukturmodelle, Verbundvorhaben MEGADESIGN. Schlussbericht. Berichtszeitraum: 01.06.2003-31.05.2007. BMBF-Forschungsbericht}, pages = {41 S.: Ill., graph. Darst.}, year = {2007}, language = {de} } @book{Braun2007, author = {Braun, Carsten}, title = {Ein modulares Verfahren f{\"u}r die numerische aeroelastische Analyse von Luftfahrzeugen}, pages = {VI, 199 S.}, year = {2007}, abstract = {Aachen, Techn. Hochschule, Diss., 2007}, language = {de} } @article{JordanKruegerWillmesetal.2011, author = {Jordan, Sabine D. and Kr{\"u}ger, Markus and Willmes, Diana M. and Redemann, Nora and Wunderlich, F. Thomas and Br{\"o}nneke, Hella S. and Merkwirth, Carsten and Kashkar, Hamid and Olkkonen, Vesa M. and B{\"o}ttger, Thomas and Braun, Thomas and Seibler, Jost and Br{\"u}ning, Jens C.}, title = {Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism}, series = {Nature Cell Biology}, volume = {13}, journal = {Nature Cell Biology}, number = {4}, publisher = {Nature}, address = {New York}, issn = {1465-7392}, doi = {10.1038/ncb2211}, pages = {434 -- 446}, year = {2011}, abstract = {The contribution of altered post-transcriptional gene silencing to the development of insulin resistance and type 2 diabetes mellitus so far remains elusive. Here, we demonstrate that expression of microRNA (miR)-143 and 145 is upregulated in the liver of genetic and dietary mouse models of obesity. Induced transgenic overexpression of miR-143, but not miR-145, impairs insulin-stimulated AKT activation and glucose homeostasis. Conversely, mice deficient for the miR-143-145 cluster are protected from the development of obesity-associated insulin resistance. Quantitative-mass-spectrometry-based analysis of hepatic protein expression in miR-143-overexpressing mice revealed miR-143-dependent downregulation of oxysterol-binding-protein-related protein (ORP) 8. Reduced ORP8 expression in cultured liver cells impairs the ability of insulin to induce AKT activation, revealing an ORP8-dependent mechanism of AKT regulation. Our experiments provide direct evidence that dysregulated post-transcriptional gene silencing contributes to the development of obesity-induced insulin resistance, and characterize the miR-143-ORP8 pathway as a potential target for the treatment of obesity-associated diabetes.}, language = {en} } @article{NeuJanserKhatibietal.2016, author = {Neu, Eugen and Janser, Frank and Khatibi, Akbar A. and Braun, Carsten and Orifici, Adrian C.}, title = {Operational Modal Analysis of a wing excited by transonic flow}, series = {Aerospace Science and Technology}, volume = {49}, journal = {Aerospace Science and Technology}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1270-9638}, doi = {10.1016/j.ast.2015.11.032}, pages = {73 -- 79}, year = {2016}, abstract = {Operational Modal Analysis (OMA) is a promising candidate for flutter testing and Structural Health Monitoring (SHM) of aircraft wings that are passively excited by wind loads. However, no studies have been published where OMA is tested in transonic flows, which is the dominant condition for large civil aircraft and is characterized by complex and unique aerodynamic phenomena. We use data from the HIRENASD large-scale wind tunnel experiment to automatically extract modal parameters from an ambiently excited wing operated in the transonic regime using two OMA methods: Stochastic Subspace Identification (SSI) and Frequency Domain Decomposition (FDD). The system response is evaluated based on accelerometer measurements. The excitation is investigated from surface pressure measurements. The forcing function is shown to be non-white, non-stationary and contaminated by narrow-banded transonic disturbances. All these properties violate fundamental OMA assumptions about the forcing function. Despite this, all physical modes in the investigated frequency range were successfully identified, and in addition transonic pressure waves were identified as physical modes as well. The SSI method showed superior identification capabilities for the investigated case. The investigation shows that complex transonic flows can interfere with OMA. This can make existing approaches for modal tracking unsuitable for their application to aircraft wings operated in the transonic flight regime. Approaches to separate the true physical modes from the transonic disturbances are discussed.}, language = {en} } @inproceedings{SchildtBraunMarcocca2017, author = {Schildt, P. and Braun, Carsten and Marcocca, P.}, title = {Flight testing the extra 330LE flying testbed}, series = {48th Annual International Symposium of the Society of Flight Test Engineers 2017}, booktitle = {48th Annual International Symposium of the Society of Flight Test Engineers 2017}, isbn = {978-151085387-4}, pages = {349 -- 362}, year = {2017}, language = {en} } @inproceedings{LudowicyRingsFingeretal.2018, author = {Ludowicy, Jonas and Rings, Ren{\´e} and Finger, Felix and Braun, Carsten}, title = {Sizing Studies of Light Aircraft with Serial Hybrid Propulsion Systems}, series = {Luft- und Raumfahrt - Digitalisierung und Vernetzung : Deutscher Luft- und Raumfahrtkongress 2018. 4. - 6. September 2018 - Friedrichshafen}, booktitle = {Luft- und Raumfahrt - Digitalisierung und Vernetzung : Deutscher Luft- und Raumfahrtkongress 2018. 4. - 6. September 2018 - Friedrichshafen}, pages = {11 S.}, year = {2018}, language = {en} }