@article{KochPoghossianSchoeningetal.2018, author = {Koch, Claudia and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Wege, Christian}, title = {Penicillin Detection by Tobacco Mosaic Virus-Assisted Colorimetric Biosensors}, series = {Nanotheranostics}, volume = {2}, journal = {Nanotheranostics}, number = {2}, publisher = {Ivyspring}, address = {Sydney}, issn = {2206-7418}, doi = {10.7150/ntno.22114}, pages = {184 -- 196}, year = {2018}, abstract = {The presentation of enzymes on viral scaffolds has beneficial effects such as an increased enzyme loading and a prolonged reusability in comparison to conventional immobilization platforms. Here, we used modified tobacco mosaic virus (TMV) nanorods as enzyme carriers in penicillin G detection for the first time. Penicillinase enzymes were conjugated with streptavidin and coupled to TMV rods by use of a bifunctional biotin-linker. Penicillinase-decorated TMV particles were characterized extensively in halochromic dye-based biosensing. Acidometric analyte detection was performed with bromcresol purple as pH indicator and spectrophotometry. The TMV-assisted sensors exhibited increased enzyme loading and strongly improved reusability, and higher analysis rates compared to layouts without viral adapters. They extended the half-life of the sensors from 4 - 6 days to 5 weeks and thus allowed an at least 8-fold longer use of the sensors. Using a commercial budget-priced penicillinase preparation, a detection limit of 100 µM penicillin was obtained. Initial experiments also indicate that the system may be transferred to label-free detection layouts.}, language = {en} } @incollection{FinkenbergerBaumeisterKoch2019, author = {Finkenberger, Isabel Maria and Baumeister, Eva-Maria and Koch, Christian}, title = {Komplement und Verst{\"a}rker : Wandel durch neue Allianzen}, series = {Komplement und Verst{\"a}rker : zum Verh{\"a}ltnis von Stadtplanung, k{\"u}nstlerischen Praktiken und Kulturinstitutionen}, booktitle = {Komplement und Verst{\"a}rker : zum Verh{\"a}ltnis von Stadtplanung, k{\"u}nstlerischen Praktiken und Kulturinstitutionen}, publisher = {JOVIS Verlag}, address = {Berlin}, isbn = {978-3-86859-578-9}, pages = {10 -- 39}, year = {2019}, language = {de} } @incollection{FinkenbergerBaumeisterKoch2019, author = {Finkenberger, Isabel Maria and Baumeister, Eva-Maria and Koch, Christian}, title = {Komplement und Verst{\"a}rker : der Diskurs geht weiter}, series = {Komplement und Verst{\"a}rker : zum Verh{\"a}ltnis von Stadtplanung, k{\"u}nstlerischen Praktiken und Kulturinstitutionen}, booktitle = {Komplement und Verst{\"a}rker : zum Verh{\"a}ltnis von Stadtplanung, k{\"u}nstlerischen Praktiken und Kulturinstitutionen}, publisher = {JOVIS Verlag}, address = {Berlin}, isbn = {978-3-86859-578-9}, pages = {40 -- 49}, year = {2019}, language = {de} } @incollection{FinkenbergerHerbertMalornyetal.2019, author = {Finkenberger, Isabel Maria and Herbert, Saskia and Malorny, Thomas and Koch, Christian}, title = {Perforierte Wirklichkeit und m{\"o}gliche Zuk{\"u}nfte : ein Gespr{\"a}ch}, series = {Komplement und Verst{\"a}rker : zum Verh{\"a}ltnis von Stadtplanung, k{\"u}nstlerischen Praktiken und Kulturinstitutionen}, booktitle = {Komplement und Verst{\"a}rker : zum Verh{\"a}ltnis von Stadtplanung, k{\"u}nstlerischen Praktiken und Kulturinstitutionen}, publisher = {JOVIS Verlag}, address = {Berlin}, isbn = {978-3-86859-578-9}, pages = {108 -- 129}, year = {2019}, language = {de} } @incollection{FinkenbergerBaumeisterKoch2019, author = {Finkenberger, Isabel Maria and Baumeister, Eva-Maria and Koch, Christian}, title = {Themen}, series = {Komplement und Verst{\"a}rker: zum Verh{\"a}ltnis von Stadtplanung, k{\"u}nstlerischen Praktiken und Kulturinstitutionen}, booktitle = {Komplement und Verst{\"a}rker: zum Verh{\"a}ltnis von Stadtplanung, k{\"u}nstlerischen Praktiken und Kulturinstitutionen}, publisher = {JOVIS Verlag}, address = {Berlin}, isbn = {978-3-86859-578-9}, pages = {50 -- 57}, year = {2019}, language = {de} } @inproceedings{GrundmannLangeDachwaldetal.2015, author = {Grundmann, Jan Thimo and Lange, Caroline and Dachwald, Bernd and Grimm, Christian and Koch, Aaron and Ulamec, Stephan}, title = {Small Spacecraft in Planetary Defence Related Applications-Capabilities, Constraints, Challenges}, series = {IEEE Aerospace Conference}, booktitle = {IEEE Aerospace Conference}, pages = {1 -- 18}, year = {2015}, abstract = {In this paper we present an overview of the characteristics and peculiarities of small spacecraft missions related to planetary defence applications. We provide a brief overview of small spacecraft missions to small solar system bodies. On this background we present recent missions and selected projects and related studies at the German Aerospace Center, DLR, that contribute to planetary defence related activities. These range from Earth orbit technology demonstrators to active science missions in interplanetary space. We provide a summary of experience from recently flown missions with DLR participation as well as a number of studies. These include PHILAE, the lander recently arrived on comet 67P/Churyumov-Gerasimenko aboard ESA's ROSETTA comet rendezvous mission, and the Mobile Asteroid Surface Scout, MASCOT, now underway to near-Earth asteroid (162173) 1999 JU3 aboard the Japanese sample-return probe HAYABUSA-2. We introduce the differences between the conventional methods employed in the design, integration and testing of large spacecraft and the new approaches developed by small spacecraft projects. We expect that the practical experience that can be gained from projects on extremely compressed timelines or with high-intensity operation phases on a newly explored small solar system body can contribute significantly to the study, preparation and realization of future planetary defence related missions. One is AIDA (Asteroid Impact \& Deflection Assessment), a joint effort of ESA,JHU/APL, NASA, OCA and DLR, combining JHU/APL's DART (Double Asteroid Redirection Test) and ESA's AIM (Asteroid Impact Monitor) spacecraft in a mission towards near-Eath binary asteroid (65803) Didymos.}, language = {en} }