@article{MuellerVeggianGarbeNouretal.2005, author = {M{\"u}ller-Veggian, Mattea and Garbe, S. and Nour, Y. and Wolf, K.}, title = {Scattered dose determination using the semiconductor diodes for a mask based whole brain radiotherapy (WBRT) with high-energy photons}, series = {Biomedizinische Technik. 50 (2005), H. 2}, journal = {Biomedizinische Technik. 50 (2005), H. 2}, isbn = {0932-4666}, pages = {1069 -- 1070}, year = {2005}, language = {en} } @article{MuellerVeggianGarbeNouretal.2005, author = {M{\"u}ller-Veggian, Mattea and Garbe, S. and Nour, Y. and Wolf, K.}, title = {468 Scatter dose determination at the eye lens during a mask based whole brain radiotherapy (WBRT)}, series = {Radiotherapy and Oncology}, volume = {76}, journal = {Radiotherapy and Oncology}, number = {Suppl. 2}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0167-8140}, doi = {10.1016/S0167-8140(05)81444-6}, pages = {S202}, year = {2005}, language = {en} } @incollection{SamuelssonScheerWilsonetal.2017, author = {Samuelsson, K. and Scheer, Nico and Wilson, I. and Wolf, C.R. and Henderson, C.J.}, title = {Genetically Humanized Animal Models}, series = {Comprehensive Medicinal Chemistry III. 3rd Edition}, booktitle = {Comprehensive Medicinal Chemistry III. 3rd Edition}, editor = {Chackalamannil, Samuel}, publisher = {Elsevier}, address = {Saint Louis}, isbn = {978-0-12-803201-5}, doi = {10.1016/B978-0-12-409547-2.12376-5}, pages = {130 -- 149}, year = {2017}, abstract = {Genetically humanized mice for proteins involved in drug metabolism and toxicity and mice engrafted with human hepatocytes are emerging as promising in vivo models for improved prediction of the pharmacokinetic, drug-drug interaction, and safety characteristics of compounds in humans. This is an overview on the genetically humanized and chimeric liver-humanized mouse models, which are illustrated with examples of their utility in drug metabolism and toxicity studies. The models are compared to give guidance for selection of the most appropriate model by highlighting advantages and disadvantages to be carefully considered when used for studies in drug discovery and development.}, language = {en} }