@article{JansenBehbahaniLaumenetal.2010, author = {Jansen, S. V. and Behbahani, Mehdi and Laumen, M. and Kaufmann, T. and Hormes, M. and Behr, M. and Schmitz-Rode, T. and Steinseifer, U.}, title = {Investigation of Steady Flow Through a Realistic Model of the Thoracic Human Aorta Using 3D Stereo PIV and CFD-Simulation}, year = {2010}, language = {en} } @article{SchmitzAltherrHofmannetal.1998, author = {Schmitz, G{\"u}nter and Altherr, M. and Hofmann, O. and Pischinger, M. (u.a.)}, title = {Anwendung moderner Simulationstools f{\"u}r die Entwicklung eines elektromagnetischen Ventilaktuators}, series = {TransMechatronik : Entwicklung und Transfer von Entwicklungssystemen der Mechatronik / Aachener Workshop TransMechatronik 26. Mai 1998, Technologiezentrum am Europaplatz}, journal = {TransMechatronik : Entwicklung und Transfer von Entwicklungssystemen der Mechatronik / Aachener Workshop TransMechatronik 26. Mai 1998, Technologiezentrum am Europaplatz}, publisher = {Heinz-Nixdorf-Inst, Univ.-GH Paderborn}, address = {Paderborn}, isbn = {3-931466-37-X}, pages = {55 -- 74}, year = {1998}, language = {de} } @article{MangHodeniusSchmitzRodeetal.2009, author = {Mang, Thomas and Hodenius, M. A. J. and Schmitz-Rode, T. and Baumann, M.}, title = {Absorption of 10-hydroxycamptothecin into the coat of magnetoliposomes / Hodenius, M. A. J. ; Schmitz-Rode, T. ; Baumann, M. ; Ivoanova, G. ; Wong, J. E. ; Mang, T. ; Haulena, F. ; Soenen, S. J. H. ; De Cuyper, M.}, series = {Colloids and Surfaces A: Physicochemical and Engineering Aspects. 343 (2009), H. 1-3}, journal = {Colloids and Surfaces A: Physicochemical and Engineering Aspects. 343 (2009), H. 1-3}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {0927-7757}, pages = {20 -- 23}, year = {2009}, language = {en} } @inproceedings{GallAbelAhlbrinketal.2009, author = {Gall, J. and Abel, D. and Ahlbrink, N. and Andersson, J. and Diehl, M. and Pitz-Paal, R. and Schmitz, M. and Teixeira Boura, Cristiano Jos{\´e}}, title = {Optimized control of hot-gas cycle for solar thermal power plants}, series = {Proceedings of the 7th International Modelica Conference : Como, Italy, 20-22 September 2009 / Francesco Casella, ed.}, booktitle = {Proceedings of the 7th International Modelica Conference : Como, Italy, 20-22 September 2009 / Francesco Casella, ed.}, publisher = {The Modelica Association}, isbn = {978-91-7393-513-5}, pages = {490 -- 495}, year = {2009}, language = {en} } @inproceedings{GallAbelAhlbrinketal.2010, author = {Gall, J. and Abel, Dirk and Ahlbrink, N. and Pitz-Paal, R. and Andersson, J. and Diehl, M. and Teixeira Boura, Cristiano Jos{\´e} and Schmitz, M. and Hoffschmidt, Bernhard}, title = {Simulation and control of solar thermal power plants}, series = {International Conference on Renewable Energies and Power Quality : ICREPQ '10 : Granada 23rd - 25th March 2010}, booktitle = {International Conference on Renewable Energies and Power Quality : ICREPQ '10 : Granada 23rd - 25th March 2010}, pages = {1 -- 5}, year = {2010}, language = {en} } @article{RoethSlabuKolvenbachetal.2015, author = {R{\"o}th, A. and Slabu, I. and Kolvenbach, K. and Engelmann, Ulrich M. and Baumann, M. and Schmitz-Rode, T. and Trahms, L. and Neumann, U.}, title = {Aufnahmekinetik von magnetischen Nanopartikeln zur Tumortherapie in humanen Pankreaskarzinomzelllinien}, series = {Zeitschrift f{\"u}r Gastroenterologie}, volume = {53}, journal = {Zeitschrift f{\"u}r Gastroenterologie}, number = {8}, publisher = {Thieme}, address = {Stuttgart}, issn = {1439-7803}, doi = {10.1055/s-0035-1559529}, pages = {KC139}, year = {2015}, language = {de} } @article{RoethSlabuEngelmannetal.2017, author = {R{\"o}th, A.A. and Slabu, I. and Engelmann, Ulrich M. and Baumann, M. and Schmitz-Rode, T. and Neumann, U. P.}, title = {Targeting von gastroenterologischen Tumoren mittels magnetischer Nanopartikel zur hyperthermischen Therapie}, series = {Zeitschrift f{\"u}r Gastroenterologie}, volume = {55}, journal = {Zeitschrift f{\"u}r Gastroenterologie}, number = {8}, publisher = {Thieme}, address = {Stuttgart}, doi = {10.1055/s-0037-1605124}, pages = {KV-384}, year = {2017}, language = {de} } @article{SlabuRoethEngelmannetal.2019, author = {Slabu, Ioana and Roeth, Anjali A. and Engelmann, Ulrich M. and Wiekhorst, Frank and Buhl, Eva M. and Neumann, Ulf P. and Schmitz-Rode, Thomas}, title = {Modeling of magnetoliposome uptake in human pancreatic tumor cells in vitro}, series = {Nanotechnology}, volume = {30}, journal = {Nanotechnology}, number = {18}, issn = {1361-6528}, doi = {10.1088/1361-6528/ab033e}, pages = {184004}, year = {2019}, language = {en} } @article{SchmitzPischinger1997, author = {Schmitz, G{\"u}nter and Pischinger, M.}, title = {Mechatronische Simulation eines EMV- Aktuators}, series = {TransMechatronik : Entwicklung und Transfer von Entwicklungssystemen der Mechatronik / Paderborner Workshop TransMechatronik, 24. Juni 1997, Heinz-Nixdorf-MuseumsForum. [Hrsg. J{\"u}rgen Gausemeier]}, journal = {TransMechatronik : Entwicklung und Transfer von Entwicklungssystemen der Mechatronik / Paderborner Workshop TransMechatronik, 24. Juni 1997, Heinz-Nixdorf-MuseumsForum. [Hrsg. J{\"u}rgen Gausemeier]}, publisher = {Heinz-Nixdorf-Inst., Univ.-GH Paderborn}, address = {Paderborn}, isbn = {3-931466-22-1}, pages = {69 -- 83}, year = {1997}, language = {de} } @article{SchmitzBartzHilgeretal.1990, author = {Schmitz, G{\"u}nter and Bartz, R. and Hilger, U. and Siedentop, M.}, title = {Intelligent Alcohol Fuel Sensor}, year = {1990}, language = {en} } @article{SchmitzRoetertPischinger1988, author = {Schmitz, G{\"u}nter and Roetert, J. and Pischinger, M.}, title = {A Fast Intelligent VMEbus System for Combustion Analysis in Engines}, series = {19th [nineteenth] International Symposium on Automotive Technology \& [and] Automation : with particular reference to cell control and quality management systems for the manufacturing industries; Monte Carlo, 24. - 28. October 1988.}, journal = {19th [nineteenth] International Symposium on Automotive Technology \& [and] Automation : with particular reference to cell control and quality management systems for the manufacturing industries; Monte Carlo, 24. - 28. October 1988.}, publisher = {Automotive Automation Ltd}, address = {Croydon}, isbn = {0947719229}, pages = {381 -- 391}, year = {1988}, language = {en} } @article{TaylorSchmitzZiemonsetal.2000, author = {Taylor, J. G. and Schmitz, N. and Ziemons, Karl and Grosse-Ruyken, M.-L. and Gruber, O. and M{\"u}ller-G{\"a}rtner, H.-W. and Shah, N. J.}, title = {The network of brain areas involved in the motion aftereffect}, series = {Neuroimage}, volume = {11}, journal = {Neuroimage}, number = {4}, isbn = {1053-8119}, pages = {257 -- 270}, year = {2000}, abstract = {A network of brain areas is expected to be involved in supporting the motion aftereffect. The most active components of this network were determined by means of an fMRI study of nine subjects exposed to a visual stimulus of moving bars producing the effect. Across the subjects, common areas were identified during various stages of the effect, as well as networks of areas specific to a single stage. In addition to the well-known motion-sensitive area MT the prefrontal brain areas BA44 and 47 and the cingulate gyrus, as well as posterior sites such as BA37 and BA40, were important components during the period of the motion aftereffect experience. They appear to be involved in control circuitry for selecting which of a number of processing styles is appropriate. The experimental fMRI results of the activation levels and their time courses for the various areas are explored. Correlation analysis shows that there are effectively two separate and weakly coupled networks involved in the total process. Implications of the results for awareness of the effect itself are briefly considered in the final discussion.}, language = {en} } @inproceedings{ZiolkoSchmitzSattleretal.2010, author = {Ziolko, C. and Schmitz, M. and Sattler, Johannes, Christoph and Khedim, Ahmed and Hoffschmidt, Bernhard}, title = {AlSol - the open volumetric receiver technology moves to Africa}, series = {SolarPACES 2010 : the CSP Conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France}, booktitle = {SolarPACES 2010 : the CSP Conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France}, publisher = {Soc. OSC}, address = {Saint Maur}, pages = {93 -- 94}, year = {2010}, language = {en} } @inproceedings{AlexopoulosHoffschmidtRauetal.2010, author = {Alexopoulos, Spiros and Hoffschmidt, Bernhard and Rau, Christoph and Schmitz, M. and Schwarzb{\"o}zl, P. and Pomp, Stefan}, title = {Simulation results for a hybridized operation of a gas turbine or a burner for a small solar tower power plant}, series = {SolarPACES 2010 : the CSP Conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France}, booktitle = {SolarPACES 2010 : the CSP Conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France}, publisher = {Soc. OSC}, address = {Saint Maur}, pages = {82 -- 83}, year = {2010}, language = {en} } @article{SchmitzHirschBongaertsetal.2002, author = {Schmitz, M. and Hirsch, E. and Bongaerts, Johannes and Takors, Ralf}, title = {Pulse experiments as a prerequisite for the quantification of in vivo enzyme kinetics in aromatic amino acid pathway of Eschericia coli}, series = {Biotechnology progress}, volume = {Vol. 18}, journal = {Biotechnology progress}, number = {Iss. 5}, issn = {1520-6033 (E-Journal); 8756-7938 (Print)}, pages = {935 -- 941}, year = {2002}, language = {en} } @article{EngelmannRoethEberbecketal.2018, author = {Engelmann, Ulrich M. and Roeth, Anjali A.J. and Eberbeck, Dietmar and Buhl, Eva Miriam and Neumann, Ulf Peter and Schmitz-Rode, Thomas and Slabu, Ioana}, title = {Combining Bulk Temperature and Nanoheating Enables Advanced Magnetic Fluid Hyperthermia Efficacy on Pancreatic Tumor Cells}, series = {Scientific Reports}, volume = {8}, journal = {Scientific Reports}, number = {1}, publisher = {Springer Nature}, address = {Cham}, issn = {2045-2322}, doi = {10.1038/s41598-018-31553-9}, pages = {Article number 13210}, year = {2018}, abstract = {Many efforts are made worldwide to establish magnetic fluid hyperthermia (MFH) as a treatment for organ-confined tumors. However, translation to clinical application hardly succeeds as it still lacks of understanding the mechanisms determining MFH cytotoxic effects. Here, we investigate the intracellular MFH efficacy with respect to different parameters and assess the intracellular cytotoxic effects in detail. For this, MiaPaCa-2 human pancreatic tumor cells and L929 murine fibroblasts were loaded with iron-oxide magnetic nanoparticles (MNP) and exposed to MFH for either 30 min or 90 min. The resulting cytotoxic effects were assessed via clonogenic assay. Our results demonstrate that cell damage depends not only on the obvious parameters bulk temperature and duration of treatment, but most importantly on cell type and thermal energy deposited per cell during MFH treatment. Tumor cell death of 95\% was achieved by depositing an intracellular total thermal energy with about 50\% margin to damage of healthy cells. This is attributed to combined intracellular nanoheating and extracellular bulk heating. Tumor cell damage of up to 86\% was observed for MFH treatment without perceptible bulk temperature rise. Effective heating decreased by up to 65\% after MNP were internalized inside cells.}, language = {en} } @article{EngelmannBuhlDraacketal.2018, author = {Engelmann, Ulrich M. and Buhl, Eva Miriam and Draack, Sebastian and Viereck, Thilo and Frank, and Schmitz-Rode, Thomas and Slabu, Ioana}, title = {Magnetic relaxation of agglomerated and immobilized iron oxide nanoparticles for hyperthermia and imaging applications}, series = {IEEE Magnetic Letters}, volume = {9}, journal = {IEEE Magnetic Letters}, number = {Article number 8519617}, publisher = {IEEE}, address = {New York, NY}, issn = {1949-307X}, doi = {10.1109/LMAG.2018.2879034}, year = {2018}, abstract = {Magnetic nanoparticles (MNPs) are used as therapeutic and diagnostic agents for local delivery of heat and image contrast enhancement in diseased tissue. Besides magnetization, the most important parameter that determines their performance for these applications is their magnetic relaxation, which can be affected when MNPs immobilize and agglomerate inside tissues. In this letter, we investigate different MNP agglomeration states for their magnetic relaxation properties under excitation in alternating fields and relate this to their heating efficiency and imaging properties. With focus on magnetic fluid hyperthermia, two different trends in MNP heating efficiency are measured: an increase by up to 23\% for agglomerated MNP in suspension and a decrease by up to 28\% for mixed states of agglomerated and immobilized MNP, which indicates that immobilization is the dominant effect. The same comparatively moderate effects are obtained for the signal amplitude in magnetic particle spectroscopy.}, language = {en} } @article{EngelmannBuhlBaumannetal.2017, author = {Engelmann, Ulrich M. and Buhl, Eva Miriam and Baumann, Martin and Schmitz-Rode, Thomas and Slabu, Ioana}, title = {Agglomeration of magnetic nanoparticles and its effects on magnetic hyperthermia}, series = {Current Directions in Biomedical Engineering}, volume = {3}, journal = {Current Directions in Biomedical Engineering}, number = {2}, publisher = {De Gruyter}, address = {Berlin}, issn = {2364-5504}, doi = {10.1515/cdbme-2017-0096}, pages = {457 -- 460}, year = {2017}, language = {en} }