@inproceedings{BohrnStuetzFleischeretal.2012,
  author    = {Bohrn, U. and St{\"u}tz, E. and Fleischer, M. and Sch{\"o}ning, Michael Josef and Wagner, P.},
  title     = {Towards a paradigm change - mammalian cells as sensitive biosensor layers for the detection of unexpected toxic substances in air},
  series = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  booktitle = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  editor    = {Abdelghani, Adnane and Sch{\"o}ning, Michael Josef},
  pages     = {44 -- 44},
  year      = {2012},
  language  = {en}
}
@article{BaeckerRaueSchusseretal.2012,
  author    = {B{\"a}cker, Matthias and Raue, Markus and Schusser, Sebastian and Jeitner, C. and Breuer, L. and Wagner, P. and Poghossian, Arshak and F{\"o}rster, Arnold and Mang, Thomas and Sch{\"o}ning, Michael Josef},
  title     = {Microfluidic chip with integrated microvalves based on temperature- and pH-responsive hydrogel thin films},
  series = {Physica Status Solidi (a)},
  volume    = {209},
  journal   = {Physica Status Solidi (a)},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201100763},
  pages     = {839 -- 845},
  year      = {2012},
  abstract  = {Two types of microvalves based on temperature-responsive poly(N-isopropylacrylamide) (PNIPAAm) and pH-responsive poly(sodium acrylate) (PSA) hydrogel films have been developed and tested. The PNIPAAm and PSA hydrogel films were prepared by means of in situ photopolymerization directly inside the fluidic channel of a microfluidic chip fabricated by combining Si and SU-8 technologies. The swelling/shrinking properties and height changes of the PNIPAAm and PSA films inside the fluidic channel were studied at temperatures of deionized water from 14 to 36 °C and different pH values (pH 3-12) of Titrisol buffer, respectively. Additionally, in separate experiments, the lower critical solution temperature (LCST) of the PNIPAAm hydrogel was investigated by means of a differential scanning calorimetry (DSC) and a surface plasmon resonance (SPR) method. Mass-flow measurements have shown the feasibility of the prepared hydrogel films to work as an on-chip integrated temperature- or pH-responsive microvalve capable to switch the flow channel on/off.},
  language  = {en}
}
@article{WernerTakenagaTakietal.2013,
  author    = {Werner, Frederik and Takenaga, Shoko and Taki, Hidenori and Sawada, Kazuaki and Sch{\"o}ning, Michael Josef},
  title     = {Comparison of label-free ACh-imaging sensors based on CCD and LAPS},
  series = {Sensors and Actuators B: Chemical (2012)},
  volume    = {177},
  journal   = {Sensors and Actuators B: Chemical (2012)},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {0925-4005},
  pages     = {745 -- 752},
  year      = {2013},
  abstract  = {Semiconductor-based chemical imaging sensors, like the light-addressable potentiometric sensor (LAPS) or the pH-imaging sensor based on a charge-coupled device (CCD), are becoming a powerful tool for label-free imaging of biological phenomena. We have proposed a polyion-based enzymatic membrane to develop an acetylcholine (ACh) imaging sensor for neural cell-activity observations. In this study, a CCD-type ACh-imaging sensor and a LAPS-type ACh-imaging sensor were fabricated and the prospect of both sensors was clarified by making a comparison of their basic characteristics.},
  language  = {en}
}
@article{KirchnerOberlaenderSucoetal.2013,
  author    = {Kirchner, Patrick and Oberl{\"a}nder, Jan and Suco, Henri-Pierre and Rysstad, Gunnar and Sch{\"o}ning, Michael Josef},
  title     = {Monitoring the microbicidal effectiveness of gaseous hydrogen peroxide in sterilisation processes by means of a calorimetric gas sensor},
  series = {Food control},
  volume    = {31},
  journal   = {Food control},
  number    = {2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-7135},
  doi       = {10.1016/j.foodcont.2012.11.048},
  pages     = {530 -- 538},
  year      = {2013},
  abstract  = {In the present work, a novel method for monitoring sterilisation processes with gaseous H2O2 in combination with heat activation by means of a specially designed calorimetric gas sensor was evaluated. Therefore, the sterilisation process was extensively studied by using test specimens inoculated with Bacillus atrophaeus spores in order to identify the most influencing process factors on its microbicidal effectiveness. Besides the contact time of the test specimens with gaseous H2O2 varied between 0.2 and 0.5 s, the present H2O2 concentration in a range from 0 to 8\% v/v (volume percent) had a strong influence on the microbicidal effectiveness, whereas the change of the vaporiser temperature, gas flow and humidity were almost negligible. Furthermore, a calorimetric H2O2 gas sensor was characterised in the sterilisation process with gaseous H2O2 in a wide range of parameter settings, wherein the measurement signal has shown a linear response against the H2O2 concentration with a sensitivity of 4.75 °C/(\% v/v). In a final step, a correlation model by matching the measurement signal of the gas sensor with the microbial inactivation kinetics was established that demonstrates its suitability as an efficient method for validating the microbicidal effectiveness of sterilisation processes with gaseous H2O2.},
  language  = {en}
}
@article{PoghossianWeilCherstvyetal.2013,
  author    = {Poghossian, Arshak and Weil, M. and Cherstvy, A. G. and Sch{\"o}ning, Michael Josef},
  title     = {Electrical monitoring of polyelectrolyte multilayer formation by means of capacitive field-effect devices},
  series = {Analytical and bioanalytical chemistry},
  volume    = {405},
  journal   = {Analytical and bioanalytical chemistry},
  number    = {20},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1432-1130 ; 1618-2642},
  doi       = {10.1007/s00216-013-6951-9},
  pages     = {6425 -- 6436},
  year      = {2013},
  abstract  = {The semiconductor field-effect platform represents a powerful tool for detecting the adsorption and binding of charged macromolecules with direct electrical readout. In this work, a capacitive electrolyte-insulator-semiconductor (EIS) field-effect sensor consisting of an Al-p-Si-SiO2 structure has been applied for real-time in situ electrical monitoring of the layer-by-layer formation of polyelectrolyte (PE) multilayers (PEM). The PEMs were deposited directly onto the SiO2 surface without any precursor layer or drying procedures. Anionic poly(sodium 4-styrene sulfonate) and cationic weak polyelectrolyte poly(allylamine hydrochloride) have been chosen as a model system. The effect of the ionic strength of the solution, polyelectrolyte concentration, number and polarity of the PE layers on the characteristics of the PEM-modified EIS sensors have been studied by means of capacitance-voltage and constant-capacitance methods. In addition, the thickness, surface morphology, roughness and wettabilityof the PE mono- and multilayers have been characterised by ellipsometry, atomic force microscopy and water contact-angle methods, respectively. To explain potential oscillations on the gate surface and signal behaviour of the capacitive field-effect EIS sensor modified with a PEM, a simplified electrostatic model that takes into account the reduced electrostatic screening of PE charges by mobile ions within the PEM has been proposed and discussed.},
  language  = {en}
}
@article{SchusserLeinhosBaeckeretal.2013,
  author    = {Schusser, Sebastian and Leinhos, Marcel and B{\"a}cker, Matthias and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Impedance spectroscopy: A tool for real-time in situ monitoring of the degradation of biopolymers},
  series = {Physica Status Solidi (A)},
  volume    = {210},
  journal   = {Physica Status Solidi (A)},
  number    = {5},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1521-396X ; 0031-8965},
  doi       = {10.1002/pssa.201200941},
  pages     = {905 -- 910},
  year      = {2013},
  abstract  = {Investigation of the degradation kinetics of biodegradable polymers is essential for the development of implantable biomedical devices with predicted biodegradability. In this work, an impedimetric sensor has been applied for real-time and in situ monitoring of degradation processes of biopolymers. The sensor consists of two platinum thin-film electrodes covered by a polymer film to be studied. The benchmark biomedical polymer poly(D,L-lactic acid) (PDLLA) was used as a model system. PDLLA films were deposited on the sensor structure from a polymer solution by using the spin-coating method. The degradation kinetics of PDLLA films have been studied in alkaline solutions of pH 9 and 12 by means of an impedance spectroscopy (IS) method. Any changes in a polymer capacitance/resistance induced by water uptake and/or polymer degradation will modulate the global impedance of the polymer-covered sensor that can be used as an indicator of the polymer degradation. The degradation rate can be evaluated from the time-dependent impedance spectra. As expected, a faster degradation has been observed for PDLLA films exposed to pH 12 solution.},
  language  = {en}
}
@article{HuckSchiffelsHerreraetal.2013,
  author    = {Huck, Christina and Schiffels, Johannes and Herrera, Cony N. and Schelden, Maximilian and Selmer, Thorsten and Poghossian, Arshak and Baumann, Marcus and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Metabolic responses of Escherichia coli upon glucose pulses captured by a capacitive field-effect sensor},
  series = {Physica Status Solidi (A)},
  volume    = {210},
  journal   = {Physica Status Solidi (A)},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0031-8965},
  doi       = {10.1002/pssa.201200900},
  pages     = {926 -- 931},
  year      = {2013},
  abstract  = {Living cells are complex biological systems transforming metabolites taken up from the surrounding medium. Monitoring the responses of such cells to certain substrate concentrations is a challenging task and offers possibilities to gain insight into the vitality of a community influenced by the growth environment. Cell-based sensors represent a promising platform for monitoring the metabolic activity and thus, the "welfare" of relevant organisms. In the present study, metabolic responses of the model bacterium Escherichia coli in suspension, layered onto a capacitive field-effect structure, were examined to pulses of glucose in the concentration range between 0.05 and 2 mM. It was found that acidification of the surrounding medium takes place immediately after glucose addition and follows Michaelis-Menten kinetic behavior as a function of the glucose concentration. In future, the presented setup can, therefore, be used to study substrate specificities on the enzymatic level and may as well be used to perform investigations of more complex metabolic responses. Conclusions and perspectives highlighting this system are discussed.},
  language  = {en}
}
@article{MuribGrinsvenGrietenetal.2013,
  author    = {Murib, M. S. and Grinsven, B. van and Grieten, L. and Janssens, S. D. and Vermeeren, V. and Eersels, K. and Broeders, J. and Ameloot, M. and Michiels, L. and Ceuninck, W. De and Haenen, K. and Sch{\"o}ning, Michael Josef and Wagner, Patrick},
  title     = {Electronic monitoring of chemical DNA denaturation on nanocrystalline diamond electrodes with different molarities and flow rates},
  series = {Physica Status Solidi (A). Vol. 210 (2013), iss. 5},
  journal   = {Physica Status Solidi (A). Vol. 210 (2013), iss. 5},
  publisher = {Wiley-VCH},
  address   = {Berlin},
  issn      = {0031-8965},
  pages     = {911 -- 917},
  year      = {2013},
  language  = {en}
}
@article{SchusserMenzelBaeckeretal.2013,
  author    = {Schusser, Sebastian and Menzel, S. and B{\"a}cker, Matthias and Leinhos, Marcel and Poghossian, Arshak and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {Degradation of thin poly(lactic acid) films: characterization by capacitance-voltage, atomic force microscopy, scanning electron microscopy and contact-angle measurements},
  series = {Electrochimica Acta},
  volume    = {Vol. 113},
  journal   = {Electrochimica Acta},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-3859 (E-Journal); 0013-4686 (Print)},
  pages     = {779 -- 784},
  year      = {2013},
  language  = {en}
}
@article{SchoeningBrinkmannRolkaetal.2005,
  author    = {Sch{\"o}ning, Michael Josef and Brinkmann, D. and Rolka, David and Demuth, C. and Poghossian, Arshak},
  title     = {CIP (cleaning-in-place) suitable "non-glass" pH sensor based on a Ta2O5-gate EIS structure},
  series = {Sensors and Actuators B: Chemical. 111-112 (2005)},
  journal   = {Sensors and Actuators B: Chemical. 111-112 (2005)},
  isbn      = {0925-4005},
  pages     = {423 -- 429},
  year      = {2005},
  language  = {en}
}
@article{PoghossianAbouzarSakkarietal.2006,
  author    = {Poghossian, Arshak and Abouzar, Maryam H. and Sakkari, M. and Kassab, T. and Han, Y. and Ingebrandt, S. and Offenh{\"a}usser, A. and Sch{\"o}ning, Michael Josef},
  title     = {Field-effect sensors for monitoring the layer-by-layer adsorption of charged macromolecules},
  series = {Sensors and Actuators B: Chemical. 118 (2006), H. 1-2},
  journal   = {Sensors and Actuators B: Chemical. 118 (2006), H. 1-2},
  isbn      = {0925-4005},
  pages     = {163 -- 170},
  year      = {2006},
  language  = {en}
}
@article{KloockMorenoBratovetal.2006,
  author    = {Kloock, Joachim P. and Moreno, Lia and Bratov, A. and Huachupoma, S. and Xu, J. and Wagner, Torsten and Yoshinobu, T. and Ermolenko, Y. and Vlasov, Y. G. and Sch{\"o}ning, Michael Josef},
  title     = {PLD-prepared cadmium sensors based on chalcogenide glasses —ISFET, LAPS and \&\#956;ISE semiconductor structures},
  series = {Sensors and Actuators B: Chemical. 118 (2006), H. 1-2},
  journal   = {Sensors and Actuators B: Chemical. 118 (2006), H. 1-2},
  isbn      = {0925-4005},
  pages     = {149 -- 155},
  year      = {2006},
  language  = {en}
}
@article{WagnerRaoKloocketal.2006,
  author    = {Wagner, Torsten and Rao, C. and Kloock, Joachim P. and Yoshinobu, T. and Otto, R. and Keusgen, M. and Sch{\"o}ning, Michael Josef},
  title     = {"LAPS Card"—A novel chip card-based light-addressable potentiometric sensor (LAPS)},
  series = {Sensors and Actuators B: Chemical. 118 (2006), H. 1-2},
  journal   = {Sensors and Actuators B: Chemical. 118 (2006), H. 1-2},
  isbn      = {0925-4005},
  pages     = {33 -- 40},
  year      = {2006},
  language  = {en}
}
@article{PoghossianAbouzarAmbergeretal.2007,
  author    = {Poghossian, Arshak and Abouzar, Maryam H. and Amberger, F. and Mayer, D. and Han, Y. and Ingebrandt, S. and Offenh{\"a}usser, A. and Sch{\"o}ning, Michael Josef},
  title     = {Field-effect sensors with charged macromolecules: Characterisation by capacitance-voltage, constant-capacitance, impedance spectroscopy and atomic-force microscopy methods},
  series = {Biosensors and Bioelectronics. 22 (2007), H. 9-10},
  journal   = {Biosensors and Bioelectronics. 22 (2007), H. 9-10},
  isbn      = {0956-5663},
  pages     = {2100 -- 2107},
  year      = {2007},
  language  = {en}
}
@article{IngebrandtHanNakamuraetal.2007,
  author    = {Ingebrandt, S. and Han, Y. and Nakamura, F. and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Offenh{\"a}usser, A.},
  title     = {Label-free detection of single nucleotide polymorphisms utilizing the differential transfer function of field-effect transistors},
  series = {Biosensors and Bioelectronics. 22 (2007), H. 12},
  journal   = {Biosensors and Bioelectronics. 22 (2007), H. 12},
  isbn      = {0956-5663},
  pages     = {2834 -- 2840},
  year      = {2007},
  language  = {en}
}
@article{PoghossianIngebrandtAbouzaretal.2007,
  author    = {Poghossian, Arshak and Ingebrandt, S. and Abouzar, Maryam H. and Sch{\"o}ning, Michael Josef},
  title     = {Label-free detection of charged macromolecules by using a field-effect-based sensor platform: Experiments and possible mechanisms of signal generation},
  series = {Applied Physics A: Materials Science \& Processing. 87 (2007), H. 3},
  journal   = {Applied Physics A: Materials Science \& Processing. 87 (2007), H. 3},
  isbn      = {0947-8396},
  pages     = {517 -- 524},
  year      = {2007},
  language  = {en}
}
@article{SiqueiraWernerBaeckeretal.2009,
  author    = {Siqueira, Jose R. and Werner, Frederik and B{\"a}cker, Matthias and Poghossian, Arshak and Zucolotto, Valtencir and Oliveira, Osvaldo N. Jr. and Sch{\"o}ning, Michael Josef},
  title     = {Layer-by-Layer Assembly of Carbon Nanotubes Incorporated in Light-Addressable Potentiometric Sensors},
  series = {Journal of Physical Chemistry C. 113 (2009), H. 33},
  journal   = {Journal of Physical Chemistry C. 113 (2009), H. 33},
  publisher = {American Chemical Society},
  address   = {Washington, DC},
  isbn      = {1932-7455},
  pages     = {14765 -- 14770},
  year      = {2009},
  language  = {en}
}
@article{AridaTurekRolkaetal.2009,
  author    = {Arida, Hassan and Turek, Monika and Rolka, David and Sch{\"o}ning, Michael Josef},
  title     = {A Novel Thin-Film Copper Array Based on an Organic/Inorganic Sensor Hybrid: Microfabrication, Potentiometric Characterization, and Flow-Injection Analysis Application},
  series = {Electroanalysis. 21 (2009), H. 10},
  journal   = {Electroanalysis. 21 (2009), H. 10},
  publisher = {Wiley},
  address   = {Weinheim},
  isbn      = {1040-0397},
  pages     = {1145 -- 1151},
  year      = {2009},
  language  = {en}
}
@article{MiyamotoKuwabaraKanohetal.2009,
  author    = {Miyamoto, K. and Kuwabara, Yohei and Kanoh, Shin'ichiro and Yoshinobu, Tatsuo and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Chemical image scanner based on FDM-LAPS},
  series = {Sensors and Actuators B: Chemical. 137 (2009), H. 2},
  journal   = {Sensors and Actuators B: Chemical. 137 (2009), H. 2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {0925-4005},
  pages     = {533 -- 538},
  year      = {2009},
  language  = {en}
}
@article{PoghossianIngebrandtOffenhaeusseretal.2009,
  author    = {Poghossian, Arshak and Ingebrandt, S. and Offenh{\"a}usser, A. and Sch{\"o}ning, Michael Josef},
  title     = {Field-effect devices for detecting cellular signals},
  series = {Seminars in Cell \& Developmental Biology. 20 (2009), H. 1},
  journal   = {Seminars in Cell \& Developmental Biology. 20 (2009), H. 1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {1096-3634},
  pages     = {41 -- 48},
  year      = {2009},
  language  = {en}
}