@article{EngelmannShashaTeemanetal.2019,
  author    = {Engelmann, Ulrich M. and Shasha, Carolyn and Teeman, Eric and Slabu, Iona and Krishnan, Kannan M.},
  title     = {Predicting size-dependent heating efficiency of magnetic nanoparticles from experiment and stochastic N{\´e}el-Brown Langevin simulation},
  series = {Journal of Magnetism and Magnetic Materials},
  volume    = {471},
  journal   = {Journal of Magnetism and Magnetic Materials},
  number    = {1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0304-8853},
  doi       = {10.1016/j.jmmm.2018.09.041},
  pages     = {450 -- 456},
  year      = {2019},
  language  = {en}
}
@article{EngelmannSeifertMuesetal.2019,
  author    = {Engelmann, Ulrich M. and Seifert, Julian and Mues, Benedikt and Roitsch, Stefan and M{\´e}nager, Christine and Schmidt, Annette M. and Slabu, Ioana},
  title     = {Heating efficiency of magnetic nanoparticles decreases with gradual immobilization in hydrogels},
  series = {Journal of Magnetism and Magnetic Materials},
  volume    = {471},
  journal   = {Journal of Magnetism and Magnetic Materials},
  number    = {1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0304-8853},
  doi       = {10.1016/j.jmmm.2018.09.113},
  pages     = {486 -- 494},
  year      = {2019},
  language  = {en}
}
@article{EngelmannRoethEberbecketal.2018,
  author    = {Engelmann, Ulrich M. and Roeth, Anjali A.J. and Eberbeck, Dietmar and Buhl, Eva Miriam and Neumann, Ulf Peter and Schmitz-Rode, Thomas and Slabu, Ioana},
  title     = {Combining Bulk Temperature and Nanoheating Enables Advanced Magnetic Fluid Hyperthermia Efficacy on Pancreatic Tumor Cells},
  series = {Scientific Reports},
  volume    = {8},
  journal   = {Scientific Reports},
  number    = {1},
  publisher = {Springer Nature},
  address   = {Cham},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-018-31553-9},
  pages     = {Article number 13210},
  year      = {2018},
  abstract  = {Many efforts are made worldwide to establish magnetic fluid hyperthermia (MFH) as a treatment for organ-confined tumors. However, translation to clinical application hardly succeeds as it still lacks of understanding the mechanisms determining MFH cytotoxic effects. Here, we investigate the intracellular MFH efficacy with respect to different parameters and assess the intracellular cytotoxic effects in detail. For this, MiaPaCa-2 human pancreatic tumor cells and L929 murine fibroblasts were loaded with iron-oxide magnetic nanoparticles (MNP) and exposed to MFH for either 30 min or 90 min. The resulting cytotoxic effects were assessed via clonogenic assay. Our results demonstrate that cell damage depends not only on the obvious parameters bulk temperature and duration of treatment, but most importantly on cell type and thermal energy deposited per cell during MFH treatment. Tumor cell death of 95\% was achieved by depositing an intracellular total thermal energy with about 50\% margin to damage of healthy cells. This is attributed to combined intracellular nanoheating and extracellular bulk heating. Tumor cell damage of up to 86\% was observed for MFH treatment without perceptible bulk temperature rise. Effective heating decreased by up to 65\% after MNP were internalized inside cells.},
  language  = {en}
}
@article{EngelmannBuhlDraacketal.2018,
  author    = {Engelmann, Ulrich M. and Buhl, Eva Miriam and Draack, Sebastian and Viereck, Thilo and Frank, and Schmitz-Rode, Thomas and Slabu, Ioana},
  title     = {Magnetic relaxation of agglomerated and immobilized iron oxide nanoparticles for hyperthermia and imaging applications},
  series = {IEEE Magnetic Letters},
  volume    = {9},
  journal   = {IEEE Magnetic Letters},
  number    = {Article number 8519617},
  publisher = {IEEE},
  address   = {New York, NY},
  issn      = {1949-307X},
  doi       = {10.1109/LMAG.2018.2879034},
  year      = {2018},
  abstract  = {Magnetic nanoparticles (MNPs) are used as therapeutic and diagnostic agents for local delivery of heat and image contrast enhancement in diseased tissue. Besides magnetization, the most important parameter that determines their performance for these applications is their magnetic relaxation, which can be affected when MNPs immobilize and agglomerate inside tissues. In this letter, we investigate different MNP agglomeration states for their magnetic relaxation properties under excitation in alternating fields and relate this to their heating efficiency and imaging properties. With focus on magnetic fluid hyperthermia, two different trends in MNP heating efficiency are measured: an increase by up to 23\% for agglomerated MNP in suspension and a decrease by up to 28\% for mixed states of agglomerated and immobilized MNP, which indicates that immobilization is the dominant effect. The same comparatively moderate effects are obtained for the signal amplitude in magnetic particle spectroscopy.},
  language  = {en}
}
@article{EngelmannBuhlBaumannetal.2017,
  author    = {Engelmann, Ulrich M. and Buhl, Eva Miriam and Baumann, Martin and Schmitz-Rode, Thomas and Slabu, Ioana},
  title     = {Agglomeration of magnetic nanoparticles and its effects on magnetic hyperthermia},
  series = {Current Directions in Biomedical Engineering},
  volume    = {3},
  journal   = {Current Directions in Biomedical Engineering},
  number    = {2},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {2364-5504},
  doi       = {10.1515/cdbme-2017-0096},
  pages     = {457 -- 460},
  year      = {2017},
  language  = {en}
}
@article{ChenJostVolkeretal.2017,
  author    = {Chen, Chao and Jost, Peter and Volker, Hanno and Kaminski, Marvin and Wirtssohn, Matti R. and Engelmann, Ulrich M. and Kr{\"u}ger, K. and Schlich, Franziska F. and Schlockermann, Carl and Lobo, Ricardo P.S.M. and Wuttig, Matthias},
  title     = {Dielectric properties of amorphous phase-change materials},
  series = {Physical Review B},
  volume    = {95},
  journal   = {Physical Review B},
  number    = {9},
  issn      = {2469-9950},
  doi       = {10.1103/PhysRevB.95.094111},
  pages     = {Article number 094111},
  year      = {2017},
  language  = {en}
}
@article{RoethSlabuKolvenbachetal.2015,
  author    = {R{\"o}th, A. and Slabu, I. and Kolvenbach, K. and Engelmann, Ulrich M. and Baumann, M. and Schmitz-Rode, T. and Trahms, L. and Neumann, U.},
  title     = {Aufnahmekinetik von magnetischen Nanopartikeln zur Tumortherapie in humanen Pankreaskarzinomzelllinien},
  series = {Zeitschrift f{\"u}r Gastroenterologie},
  volume    = {53},
  journal   = {Zeitschrift f{\"u}r Gastroenterologie},
  number    = {8},
  publisher = {Thieme},
  address   = {Stuttgart},
  issn      = {1439-7803},
  doi       = {10.1055/s-0035-1559529},
  pages     = {KC139},
  year      = {2015},
  language  = {de}
}
@article{RoethSlabuEngelmannetal.2017,
  author    = {R{\"o}th, A.A. and Slabu, I. and Engelmann, Ulrich M. and Baumann, M. and Schmitz-Rode, T. and Neumann, U. P.},
  title     = {Targeting von gastroenterologischen Tumoren mittels magnetischer Nanopartikel zur hyperthermischen Therapie},
  series = {Zeitschrift f{\"u}r Gastroenterologie},
  volume    = {55},
  journal   = {Zeitschrift f{\"u}r Gastroenterologie},
  number    = {8},
  publisher = {Thieme},
  address   = {Stuttgart},
  doi       = {10.1055/s-0037-1605124},
  pages     = {KV-384},
  year      = {2017},
  language  = {de}
}
@phdthesis{Engelmann2019,
  author    = {Engelmann, Ulrich M.},
  title     = {Assessing magnetic fluid hyperthermia : magnetic relaxation simulation, modeling of nanoparticle uptake inside pancreatic tumor cells and in vitro efficacy},
  publisher = {Infinite Science Publishing},
  address   = {L{\"u}beck},
  isbn      = {978-3-945954-58-4},
  year      = {2019},
  language  = {en}
}
@misc{Engelmann2019,
  author    = {Engelmann, Ulrich M.},
  title     = {Gespr{\"a}chsf{\"u}hrungskompetenzen f{\"u}r Naturwissenschaftler und Ingenieure. Maßnahmen zur F{\"o}rderung und curricularen Verankerung von Gespr{\"a}chsf{\"u}hrungskompetenzen an Fachhochschulen},
  publisher = {Deutsche Gesellschaft f{\"u}r Sprechwissenschaft und Sprecherziehung (DGSS e.V.)},
  address   = {Aachen},
  doi       = {10.13140/RG.2.2.34026.98248},
  pages     = {121 Seiten},
  year      = {2019},
  language  = {de}
}
@article{RoethSlabuKessleretal.2019,
  author    = {Roeth, A.A. and Slabu, I. and Kessler, A. and Engelmann, Ulrich M.},
  title     = {Local treatment of pancreatic cancer with magnetic nanoparticles},
  series = {HPB},
  volume    = {21},
  journal   = {HPB},
  number    = {Supplement 3},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1365-182X},
  doi       = {10.1016/j.hpb.2019.10.959},
  pages     = {S868 -- S869},
  year      = {2019},
  language  = {en}
}
@article{GrundlachBaumannEngelmann2021,
  author    = {Grundlach, Michael and Baumann, Martin and Engelmann, Ulrich M.},
  title     = {How Multimodal Examinations Can Increase Sustainable Student Gain by Aligning Teaching and Assessment},
  series = {Current Directions in Biomedical Engineering},
  volume    = {7},
  journal   = {Current Directions in Biomedical Engineering},
  number    = {7/2},
  editor    = {D{\"o}ssel, Olaf},
  publisher = {De Gruyter},
  address   = {Berlin},
  isbn      = {2364-5504},
  doi       = {10.1515/cdbme-2021-2019},
  pages     = {73 -- 76},
  year      = {2021},
  abstract  = {Modern industry and multi-discipline projects require highly trained individuals with resilient science and engineering back-grounds. Graduates must be able to agilely apply excellent theoretical knowledge in their subject matter as well as essential practical "hands-on" knowledge of diverse working processes to solve complex problems. To meet these demands, university education follows the concept of Constructive Alignment and thus increasingly adopts the teaching of necessary practical skills to the actual industry requirements and assessment routines. However, a systematic approach to coherently align these three central teaching demands is strangely absent from current university curricula. We demonstrate the feasibility of implementing practical assessments in a regular theory-based examination, thus defining the term "blended assessment". We assessed a course for natural science and engineering students pursuing a career in biomedical engineering, and evaluated the benefit of blended assessment exams for students and lecturers. Our controlled study assessed the physiological background of electrocardiograms (ECGs), the practical measurement of ECG curves, and their interpretation of basic pathologic alterations. To study on long time effects, students have been assessed on the topic twice with a time lag of 6 months. Our findings suggest a significant improvement in student gain with respect to practical skills and theoretical knowledge. The results of the reassessments support these outcomes. From the lecturers' point of view, blended assessment complements practical training courses while keeping organizational effort manageable. We consider blended assessment a viable tool for providing an improved student gain, industry-ready education format that should be evaluated and established further to prepare university graduates optimally for their future careers.},
  language  = {en}
}
@book{Engelmann2022,
  author    = {Engelmann, Ulrich M.},
  title     = {Zielf{\"u}hrend moderieren},
  publisher = {UVK Verlag},
  address   = {Stuttgart},
  isbn      = {9783838556895},
  doi       = {10.36198/9783838556895},
  pages     = {438 S.},
  year      = {2022},
  abstract  = {In der Teamarbeit wird Moderation zum Erfolgsfaktor, der jedoch h{\"a}ufig untersch{\"a}tzt wird. Ausgehend vom pers{\"o}nlichen Kompetenzniveau verkn{\"u}pft dieses Buch Grundlagen und Methoden zu Wegen, um Ihre pers{\"o}nliche Entwicklung individuell zu begleiten: Neulinge finden hilfreiche Checklisten und Basistechniken f{\"u}r ihre ersten Moderationen, Fortgeschrittene wertvolle Praxistipps und Methoden f{\"u}r den Ausbau ihrer Moderationskompetenz. Profis schließlich genießen eine raffinierte Aussicht auf weniger bekannte Techniken und neue Anwendungen. Weiterf{\"u}hrende Exkurse zum Meeting-Management und zur Online-Moderation runden den Anwendungshorizont ab. Ob in Beruf, Studium oder Ehrenamt - derart ausgestattet gelingen Ihre eigene sowie die Entwicklung Ihres Teams durch zielf{\"u}hrende Moderationen.},
  language  = {de}
}
@incollection{EngelmannBaumann2023,
  author    = {Engelmann, Ulrich M. and Baumann, Martin},
  title     = {Moderationsexpertise f{\"u}r QMBs - Onlinemoderation},
  series = {Qualit{\"a}tsmanagement im Gesundheitswesen},
  booktitle = {Qualit{\"a}tsmanagement im Gesundheitswesen},
  editor    = {Herbig, Nicola and Poppelreuter, Stefan},
  publisher = {T{\"U}V-Verlag},
  address   = {K{\"o}ln},
  isbn      = {978-3-8249-0714-4},
  pages     = {Kapitel 10816},
  year      = {2023},
  abstract  = {Damit Sie auch in den immer h{\"a}ufiger werdenden Onlineveranstaltungen als Moderator gut bestehen, sollten Sie wissen, was bei der Onlinemoderation im Besonderen zu beachten ist. In diesem dritten Teil der Beitragsserie erfahren Sie, warum online anders als offline ist. Die technischen M{\"o}glichkeiten werden vorgestellt und auch wie diese zu nutzen sind. Schließlich erhalten Sie Tipps, die Sie beim Sprechen online beachten sollten.},
  language  = {de}
}
@incollection{Engelmann2023,
  author    = {Engelmann, Ulrich M.},
  title     = {Moderationsexpertise - Onlinemoderation},
  series = {IT-Servicemanagement},
  booktitle = {IT-Servicemanagement},
  editor    = {Lindinger, Markus and Bartsch, Oliver},
  publisher = {T{\"U}V-Verlag},
  address   = {K{\"o}ln},
  isbn      = {978-3-8249-1154-7},
  pages     = {Kapitel 05532},
  year      = {2023},
  abstract  = {Damit Sie auch in den immer h{\"a}ufiger werdenden Onlineveranstaltungen als Moderator gut bestehen, sollten Sie wissen, was bei der Onlinemoderation im Besonderen zu beachten ist. In diesem dritten Teil der Beitragsserie erfahren Sie, warum online anders als offline ist. Die technischen M{\"o}glichkeiten werden vorgestellt und auch wie diese zu nutzen sind. Schließlich erhalten Sie Tipps, die Sie beim Sprechen online beachten sollten.},
  language  = {de}
}
@incollection{EngelmannBaumann2022,
  author    = {Engelmann, Ulrich M. and Baumann, Martin},
  title     = {Moderationsexpertise f{\"u}r QMBs - das Mindset},
  series = {Qualit{\"a}tsmanagement im Gesundheitswesen},
  booktitle = {Qualit{\"a}tsmanagement im Gesundheitswesen},
  editor    = {Herbig, Nicola and Poppelreuter, Stefan},
  edition   = {59. Update},
  publisher = {T{\"U}V-Verlag},
  address   = {K{\"o}ln},
  isbn      = {978-3-8249-0714-4},
  pages     = {Kapitel 10814},
  year      = {2022},
  abstract  = {Teamsitzungen, Arbeitsgruppentreffen, Kickoffs und Meetings - sie alle werden mit dem Ziel durchgef{\"u}hrt, innerhalb einer vorgegebenen Zeitspanne ein gemeinsames Arbeitsziel zu erreichen. Damit die Zielerreichung auch bei komplexeren Arbeitsauftr{\"a}gen nicht vom Zufall abh{\"a}ngt, empfiehlt es sich, die Leitung des Ablaufs einem Moderator zu {\"u}bertragen. In diesem Beitrag einer mehrteiligen Serie wird beschrieben, {\"u}ber welches Mindset der Moderator verf{\"u}gen sollte, welche grunds{\"a}tzlichen Methoden hilfreich sind und was bei der Onlinemoderation im Besonderen zu beachten ist.},
  language  = {de}
}
@article{EngelmannPourshahidiShalabyetal.2022,
  author    = {Engelmann, Ulrich M. and Pourshahidi, Mohammad Ali and Shalaby, Ahmed and Krause, Hans-Joachim},
  title     = {Probing particle size dependency of frequency mixing magnetic detection with dynamic relaxation simulation},
  series = {Journal of Magnetism and Magnetic Materials},
  volume    = {563},
  journal   = {Journal of Magnetism and Magnetic Materials},
  number    = {In progress, Art. No. 169965},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0304-8853},
  doi       = {10.1016/j.jmmm.2022.169965},
  year      = {2022},
  abstract  = {Biomedical applications of magnetic nanoparticles (MNP) fundamentally rely on the particles' magnetic relaxation as a response to an alternating magnetic field. The magnetic relaxation complexly depends on the interplay of MNP magnetic and physical properties with the applied field parameters. It is commonly accepted that particle core size is a major contributor to signal generation in all the above applications, however, most MNP samples comprise broad distribution spanning nm and more. Therefore, precise knowledge of the exact contribution of individual core sizes to signal generation is desired for optimal MNP design generally for each application. Specifically, we present a magnetic relaxation simulation-driven analysis of experimental frequency mixing magnetic detection (FMMD) for biosensing to quantify the contributions of individual core size fractions towards signal generation. Applying our method to two different experimental MNP systems, we found the most dominant contributions from approx. 20 nm sized particles in the two independent MNP systems. Additional comparison between freely suspended and immobilized MNP also reveals insight in the MNP microstructure, allowing to use FMMD for MNP characterization, as well as to further fine-tune its applicability in biosensing.},
  language  = {en}
}
@article{EngelmannShalabyShashaetal.2021,
  author    = {Engelmann, Ulrich M. and Shalaby, Ahmed and Shasha, Carolyn and Krishnan, Kannan M. and Krause, Hans-Joachim},
  title     = {Comparative modeling of frequency mixing measurements of magnetic nanoparticles using micromagnetic simulations and Langevin theory},
  series = {Nanomaterials},
  volume    = {11},
  journal   = {Nanomaterials},
  number    = {5},
  publisher = {MDPI},
  address   = {Basel},
  isbn      = {2079-4991},
  doi       = {10.3390/nano11051257},
  pages     = {1 -- 16},
  year      = {2021},
  abstract  = {Dual frequency magnetic excitation of magnetic nanoparticles (MNP) enables enhanced biosensing applications. This was studied from an experimental and theoretical perspective: nonlinear sum-frequency components of MNP exposed to dual-frequency magnetic excitation were measured as a function of static magnetic offset field. The Langevin model in thermodynamic equilibrium was fitted to the experimental data to derive parameters of the lognormal core size distribution. These parameters were subsequently used as inputs for micromagnetic Monte-Carlo (MC)-simulations. From the hysteresis loops obtained from MC-simulations, sum-frequency components were numerically demodulated and compared with both experiment and Langevin model predictions. From the latter, we derived that approximately 90\% of the frequency mixing magnetic response signal is generated by the largest 10\% of MNP. We therefore suggest that small particles do not contribute to the frequency mixing signal, which is supported by MC-simulation results. Both theoretical approaches describe the experimental signal shapes well, but with notable differences between experiment and micromagnetic simulations. These deviations could result from Brownian relaxations which are, albeit experimentally inhibited, included in MC-simulation, or (yet unconsidered) cluster-effects of MNP, or inaccurately derived input for MC-simulations, because the largest particles dominate the experimental signal but concurrently do not fulfill the precondition of thermodynamic equilibrium required by Langevin theory.},
  language  = {en}
}
@inproceedings{SimsekKrauseEngelmann2024,
  author    = {Simsek, Beril and Krause, Hans-Joachim and Engelmann, Ulrich M.},
  title     = {Magnetic biosensing with magnetic nanoparticles: Simulative approach to predict signal intensity in frequency mixing magnetic detection},
  series = {YRA MedTech Symposium (2024)},
  booktitle = {YRA MedTech Symposium (2024)},
  editor    = {Digel, Ilya and Staat, Manfred and Trzewik, J{\"u}rgen and Sielemann, Stefanie and Erni, Daniel and Zylka, Waldemar},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-65-3},
  doi       = {10.17185/duepublico/81475},
  pages     = {27 -- 28},
  year      = {2024},
  abstract  = {Magnetic nanoparticles (MNP) are investigated with great interest for biomedical applications in diagnostics (e.g. imaging: magnetic particle imaging (MPI)), therapeutics (e.g. hyperthermia: magnetic fluid hyperthermia (MFH)) and multi-purpose biosensing (e.g. magnetic immunoassays (MIA)). What all of these applications have in common is that they are based on the unique magnetic relaxation mechanisms of MNP in an alternating magnetic field (AMF). While MFH and MPI are currently the most prominent examples of biomedical applications, here we present results on the relatively new biosensing application of frequency mixing magnetic detection (FMMD) from a simulation perspective. In general, we ask how the key parameters of MNP (core size and magnetic anisotropy) affect the FMMD signal: by varying the core size, we investigate the effect of the magnetic volume per MNP; and by changing the effective magnetic anisotropy, we study the MNPs' flexibility to leave its preferred magnetization direction. From this, we predict the most effective combination of MNP core size and magnetic anisotropy for maximum signal generation.},
  language  = {en}
}
@incollection{EngelmannBaumann2023,
  author    = {Engelmann, Ulrich M. and Baumann, Martin},
  title     = {Moderationsexpertise f{\"u}r QMBs - die Methoden},
  series = {Qualit{\"a}tsmanagement im Gesundheitswesen},
  booktitle = {Qualit{\"a}tsmanagement im Gesundheitswesen},
  editor    = {Herbig, Nicola and Poppelreuter, Stefan},
  edition   = {60. Update},
  publisher = {T{\"U}V-Verlag},
  address   = {K{\"o}ln},
  isbn      = {978-3-8249-0714-4},
  pages     = {Kapitel 10815},
  year      = {2023},
  abstract  = {Damit Sie als Moderator effektiv und professionell moderieren k{\"o}nnen, sollten Sie die entsprechenden Methoden kennen. Mit den richtigen Methoden k{\"o}nnen Sie Diskussionen leiten, Konflikte l{\"o}sen, die Teilnehmer motivieren und daf{\"u}r sorgen, dass die Ziele der Veranstaltung erreicht werden. Außerdem helfen sie Ihnen, eine positive Atmosph{\"a}re zu schaffen und das Interesse der Teilnehmer zu halten. In diesem zweiten Beitrag der mehrteiligen Serie lernen Sie die grunds{\"a}tzlichen Methoden kennen, um erfolgreiche Teamsitzungen, Arbeitsgruppentreffen, Kick-offs und Meetings durchzuf{\"u}hren.},
  language  = {de}
}