@incollection{WendorffEggertPohletal.2007, author = {Wendorff, Marion and Eggert, Thorsten and Pohl, Martina and Dresen, Carola and M{\"u}ller, Michael and Jaeger, Karl-Erich and Sprenger, Georg A. and Sch{\"u}rmann, Melanie and Sch{\"u}rmann, Martin and Johnen, Sandra and Sprenger, Gerda and Sahm, Hermann and Inoue, Tomoyuki and Sch{\"o}rken, Ulrich and Breittaupt, Holger and Fr{\"o}lich, Bettina and Heim, Petra and Iding, Hans and Juchem, Bettina and Siegert, Petra and Kula, Maria-Regina and Weckbecker, Andrea and Hummel, Werner and Fessner, Wolf-Dieter and Elling, Lothar and Wolberg, Michael and Bode, Silke and Feldmann, Ralf and Geilenkirchen, Petra and Schubert, Thomas and Walter, Lydia and D{\"u}nnwald, Thomas and Demir, Ayhan S. and Kolter-Jung, Doris and Nitsche, Adam and D{\"u}nkelmann, Pascal and Cosp, Annabel and Lingen, Bettina}, title = {Catalytic asymmetric synthesis : section 2.2}, series = {Asymmetric synthesis with chemical and biological methods / ed. by Dieter Enders ...}, booktitle = {Asymmetric synthesis with chemical and biological methods / ed. by Dieter Enders ...}, publisher = {Wiley-VCH}, address = {Weinheim}, isbn = {978-3-527-31473-7}, pages = {298 -- 413}, year = {2007}, language = {en} } @article{EschFunkeRoosenetal.2011, author = {Esch, Thomas and Funke, Harald and Roosen, Peter and Jarolimek, Ulrich}, title = {Biogene Automobilkraftstoffe in der allgemeinen Luftfahrt}, series = {Motortechnische Zeitschrift (MTZ).}, volume = {72}, journal = {Motortechnische Zeitschrift (MTZ).}, number = {1}, publisher = {Springer Nature}, address = {Basel}, isbn = {0024-8525}, doi = {10.1365/s35146-011-0013-7}, pages = {54 -- 59}, year = {2011}, language = {de} } @article{EschFunkeRoosenetal.2011, author = {Esch, Thomas and Funke, Harald and Roosen, Peter and Jarolimek, Ulrich}, title = {Biogenic Vehicle Fuels in General Aviation Aircrafts}, series = {MTZ worldwide. 72 (2011), H. 1}, journal = {MTZ worldwide. 72 (2011), H. 1}, publisher = {Springer Automotive Media}, address = {Wiesbaden}, pages = {38 -- 43}, year = {2011}, language = {en} } @article{JahnkeMenzelDusschotenetal.2009, author = {Jahnke, Siegfried and Menzel, Marion I. and Dusschoten, Dagmar van and Roeb, Gerhard W. and B{\"u}hler, Jonas and Minwuyelet, Senay and Bl{\"u}mler, Peter and Temperton, Vicky M. and Hombach, Thomas and Streun, Matthias and Beer, Simone and Khodaverdi, Maryam and Ziemons, Karl and Coenen, Heinz H. and Schurr, Ulrich}, title = {Combined MRI-PET dissects dynamic changes in plant structures and functions}, series = {The Plant Journal}, volume = {59}, journal = {The Plant Journal}, number = {4}, publisher = {Wiley}, address = {Weinheim}, isbn = {1365-313X}, pages = {634 -- 644}, year = {2009}, abstract = {Unravelling the factors determining the allocation of carbon to various plant organs is one of the great challenges of modern plant biology. Studying allocation under close to natural conditions requires non-invasive methods, which are now becoming available for measuring plants on a par with those developed for humans. By combining magnetic resonance imaging (MRI) and positron emission tomography (PET), we investigated three contrasting root/shoot systems growing in sand or soil, with respect to their structures, transport routes and the translocation dynamics of recently fixed photoassimilates labelled with the short-lived radioactive carbon isotope 11C. Storage organs of sugar beet (Beta vulgaris) and radish plants (Raphanus sativus) were assessed using MRI, providing images of the internal structures of the organs with high spatial resolution, and while species-specific transport sectoralities, properties of assimilate allocation and unloading characteristics were measured using PET. Growth and carbon allocation within complex root systems were monitored in maize plants (Zea mays), and the results may be used to identify factors affecting root growth in natural substrates or in competition with roots of other plants. MRI-PET co-registration opens the door for non-invasive analysis of plant structures and transport processes that may change in response to genomic, developmental or environmental challenges. It is our aim to make the methods applicable for quantitative analyses of plant traits in phenotyping as well as in understanding the dynamics of key processes that are essential to plant performance.}, language = {en} } @article{SteinseiferKashefiHormesetal.2009, author = {Steinseifer, Ulrich and Kashefi, Ali and Hormes, Marcus and Schoberer, Mark and Orlikowsky, Thorsten and Behbahani, Mehdi and Behr, Marek and Schmitz-Rode, Thomas}, title = {Miniaturization of ECMO Systems : Engineering Challenges and Methods}, series = {Artificial Organs. 33 (2009), H. 5}, journal = {Artificial Organs. 33 (2009), H. 5}, isbn = {1525-1594}, pages = {A55 -- A55}, year = {2009}, language = {en} } @article{JansenBehbahaniLaumenetal.2010, author = {Jansen, Sebastian and Behbahani, Mehdi and Laumen, Marco and Kaufmann, Tim and Hormes, Marcus and Schmitz-Rode, Thomas and Behr, Marek and Steinseifer, Ulrich}, title = {3D Stereo-PIV Validation for CFD-Simulation of Steady Flow through the Human Aorta using Rapid-Prototyping techniques}, year = {2010}, language = {en} } @article{ImmelGrothHuhnetal.2011, author = {Immel, Timo A. and Groth, Ulrich and Huhn, Thomas and {\"O}hlschl{\"a}ger, Peter}, title = {Titanium salan complexes displays strong antitumor properties in vitro and in vivo in mice}, series = {PLoS ONE}, volume = {6}, journal = {PLoS ONE}, number = {3}, publisher = {Plos}, address = {San Francisco, California, US}, doi = {10.1371/journal.pone.0017869}, pages = {e17869}, year = {2011}, abstract = {The anticancer activity of titanium complexes has been known since the groundbreaking studies of K{\"o}pf and K{\"o}pf-Maier on titanocen dichloride. Unfortunately, possibly due to their fast hydrolysis, derivatives of titanocen dichloride failed in clinical studies. Recently, the new family of titanium salan complexes containing tetradentate ONNO ligands with anti-cancer properties has been discovered. These salan complexes are much more stabile in aqueous media. In this study we describe the biological activity of two titanium salan complexes in a mouse model of cervical cancer. High efficiency of this promising complex family was demonstrated for the first time in vivo. From these data we conclude that titanium salan complexes display very strong antitumor properties exhibiting only minor side effects. Our results may influence the chemotherapy with metallo therapeutics in the future.}, language = {en} } @article{MartinHardtMeissburgeretal.1983, author = {Martin, Siegfried A. and Hardt, Arno and Meissburger, J{\"u}rgen and Berg, Georg P. A. and Hacker, Ulrich and H{\"u}rlimann, Werner and R{\"o}mer, Josef G. M. and Sagefka, Thomas and Retz, Adolf and Schult, Otto W. B.}, title = {The QQDDQ magnet spectrometer "BIG KARL"}, series = {Nuclear instruments and methods in physics research. Vol. 214, iss. 2-3}, journal = {Nuclear instruments and methods in physics research. Vol. 214, iss. 2-3}, issn = {0029-554x (E-Journal); 1872-9606 (E-Journal); 0167-5087 (Print)}, pages = {281 -- 303}, year = {1983}, language = {en} } @article{GosslaBoescheBrunner2007, author = {Gossla, Ulrich and B{\"o}sche, Thomas and Brunner, Andreas}, title = {Untersuchungen zur Verbesserung der Erkenntnisse {\"u}ber das Tragverhalten der Vorlandb{\"o}gen der Eisenbahn-Marienbr{\"u}cke Dresden / B{\"o}sche, Thomas ; Gossla, Ulrich ; Brunner, Andreas}, series = {4. Symposium Experimentelle Untersuchungen von Baukonstruktionen : 27. September 2007 / Technische Universit{\"a}t Dresden, Fakult{\"a}t Bauingenieurwesen. [Hrsg. dieses Bd. Manfred Curbach ...].}, journal = {4. Symposium Experimentelle Untersuchungen von Baukonstruktionen : 27. September 2007 / Technische Universit{\"a}t Dresden, Fakult{\"a}t Bauingenieurwesen. [Hrsg. dieses Bd. Manfred Curbach ...].}, publisher = {Techn. Univ., Fak. Bauingenieurwesen}, address = {Dresden}, pages = {103 -- 114}, year = {2007}, language = {de} } @book{AppelBraehlerDahlhausetal.2010, author = {Appel, Wolfgang and Br{\"a}hler, Hermann and Dahlhaus, Ulrich and Esch, Thomas and Kopp, Stephan and Rhein, Bernd}, title = {Nutzfahrzeugtechnik : Grundlagen, Systeme, Komponenten. 6., {\"u}berarb. Aufl.}, publisher = {Vieweg + Teubner}, address = {Wiesbaden}, isbn = {978-3-8348-9757-2}, pages = {XXVIII, 509 S. : Ill., graph. Darst.}, year = {2010}, language = {de} } @book{AppelBraehlerBreueretal.2013, author = {Appel, Wolfgang and Br{\"a}hler, Hermann and Breuer, Stefan and Dahlhaus, Ulrich and Esch, Thomas and Hoepke, Erich and Kopp, Stephan and Rhein, Bernd}, title = {Nutzfahrzeugtechnik : Grundlagen, Systeme, Komponenten. 7., {\"u}berarb. u. erw. Aufl.}, publisher = {Vieweg + Teubner}, address = {Wiesbaden}, isbn = {978-3-8348-2224-6}, pages = {XXXII, 620 S. : Ill., graph. Darst.}, year = {2013}, language = {de} } @article{DiltheySchleserHanischetal.2006, author = {Dilthey, Ulrich and Schleser, Markus and Hanisch, Vera and Gries, Thomas}, title = {Garnzugpr{\"u}fung polymergetr{\"a}nkter Textilien f{\"u}r die Bewehrung von Beton}, series = {Technische Textilien}, volume = {49}, journal = {Technische Textilien}, number = {1}, issn = {0323-3243}, pages = {48 -- 50}, year = {2006}, language = {de} } @inproceedings{KolkmannGriesSchleseretal.2005, author = {Kolkmann, Annette and Gries, Thomas and Schleser, Markus and Dilthey, Ulrich}, title = {Innovative yarn structures and coatings for textile reinforced concrete}, series = {All lectures / Techtextil Symposium : 6. - 9. 6.2005, Frankfurt am Main}, booktitle = {All lectures / Techtextil Symposium : 6. - 9. 6.2005, Frankfurt am Main}, address = {Frankfurt a.M.}, pages = {1 CD-ROM}, year = {2005}, language = {en} } @article{RiglingBiglerEilmannetal.2012, author = {Rigling, Andreas and Bigler, Christof and Eilmann, Britta and Feldmeyer-Christe, Elisabeth and Gimmi, Urs and Ginzler, Christian and Graf, Ulrich and Mayer, Phillip and Vacchiano, Giorgio and Weber, Pascal and Wohlgemuth, Thomas and zweifel, Roman and Dobbertin, Matthias}, title = {Driving factors of a vegetation shift from Scots pine to pubescent oak in dry Alpine forests}, series = {Global Change Biology}, volume = {19}, journal = {Global Change Biology}, number = {1}, publisher = {Wiley-Blackwell}, address = {Oxford}, issn = {1354-1013 (Print)}, doi = {10.1111/gcb.12038}, pages = {229 -- 240}, year = {2012}, abstract = {An increasing number of studies have reported on forest declines and vegetation shifts triggered by drought. In the Swiss Rhone valley (Valais), one of the driest inner-Alpine regions, the species composition in low elevation forests is changing: The sub-boreal Scots pine (Pinus sylvestris L.) dominating the dry forests is showing high mortality rates. Concurrently the sub-Mediterranean pubescent oak (Quercus pubescens Willd.) has locally increased in abundance. However, it remains unclear whether this local change in species composition is part of a larger-scale vegetation shift. To study variability in mortality and regeneration in these dry forests we analysed data from the Swiss national forest inventory (NFI) on a regular grid between 1983 and 2003, and combined it with annual mortality data from a monitoring site. Pine mortality was found to be highest at low elevation (below 1000 m a.s.l.). Annual variation in pine mortality was correlated with a drought index computed for the summer months prior to observed tree death. A generalized linear mixed-effects model indicated for the NFI data increased pine mortality on dryer sites with high stand competition, particularly for small-diameter trees. Pine regeneration was low in comparison to its occurrence in the overstorey, whereas oak regeneration was comparably abundant. Although both species regenerated well at dry sites, pine regeneration was favoured at cooler sites at higher altitude and oak regeneration was more frequent at warmer sites, indicating a higher adaptation potential of oaks under future warming. Our results thus suggest that an extended shift in species composition is actually occurring in the pine forests in the Valais. The main driving factors are found to be climatic variability, particularly drought, and variability in stand structure and topography. Thus, pine forests at low elevations are developing into oak forests with unknown consequences for these ecosystems and their goods and services.}, language = {en} } @article{ImmelGruetzkeSpaeteetal.2012, author = {Immel, Timo and Gr{\"u}tzke, Martin and Sp{\"a}te, Anne-Katrin and Groth, Ulrich and {\"O}hlschl{\"a}ger, Peter and Huhn, Thomas}, title = {Synthesis and X-ray structure analysis of a heptacoordinate titanium(IV)-bis-chelate with enhanced in vivo antitumor efficacy}, series = {Chemical Communications}, volume = {48}, journal = {Chemical Communications}, number = {46}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1364-548X}, doi = {10.1039/C2CC31624B}, pages = {5790 -- 5792}, year = {2012}, abstract = {Chelate stabilization of a titanium(IV)-salan alkoxide by ligand exchange with 2,6-pyridinedicarboxylic acid (dipic) resulted in heptacoordinate complex 3 which is not redox-active, stable on silica gel and has increased aqueous stability. 3 is highly toxic in HeLa S3 and Hep G2 and has enhanced antitumor efficacy in a mouse cervical-cancer model.}, language = {en} } @incollection{BurgerKirschMarcheretal.2014, author = {Burger, Ulrich and Kirsch, Ansgar and Marcher, Thomas and H{\"o}ser, Sebastian}, title = {Geologisch-geotechnischer Planungsprozess von Tunnelbauten mit Schwerpunkt tiefliegender Tunnel}, series = {Beton-Kalender ; Bd. 103: Unterirdisches Bauen, Grundbau, Eurocode 7}, booktitle = {Beton-Kalender ; Bd. 103: Unterirdisches Bauen, Grundbau, Eurocode 7}, publisher = {Ernst}, address = {Berlin}, isbn = {978-3-433-03051-6 ; 978-3-433-60335-2 ; 978-3-433-60508-0 ; 3-433-60508-4}, pages = {37 -- 62}, year = {2014}, language = {de} } @article{SlabuRoethEngelmannetal.2019, author = {Slabu, Ioana and Roeth, Anjali A. and Engelmann, Ulrich M. and Wiekhorst, Frank and Buhl, Eva M. and Neumann, Ulf P. and Schmitz-Rode, Thomas}, title = {Modeling of magnetoliposome uptake in human pancreatic tumor cells in vitro}, series = {Nanotechnology}, volume = {30}, journal = {Nanotechnology}, number = {18}, issn = {1361-6528}, doi = {10.1088/1361-6528/ab033e}, pages = {184004}, year = {2019}, language = {en} } @article{EngelmannRoethEberbecketal.2018, author = {Engelmann, Ulrich M. and Roeth, Anjali A.J. and Eberbeck, Dietmar and Buhl, Eva Miriam and Neumann, Ulf Peter and Schmitz-Rode, Thomas and Slabu, Ioana}, title = {Combining Bulk Temperature and Nanoheating Enables Advanced Magnetic Fluid Hyperthermia Efficacy on Pancreatic Tumor Cells}, series = {Scientific Reports}, volume = {8}, journal = {Scientific Reports}, number = {1}, publisher = {Springer Nature}, address = {Cham}, issn = {2045-2322}, doi = {10.1038/s41598-018-31553-9}, pages = {Article number 13210}, year = {2018}, abstract = {Many efforts are made worldwide to establish magnetic fluid hyperthermia (MFH) as a treatment for organ-confined tumors. However, translation to clinical application hardly succeeds as it still lacks of understanding the mechanisms determining MFH cytotoxic effects. Here, we investigate the intracellular MFH efficacy with respect to different parameters and assess the intracellular cytotoxic effects in detail. For this, MiaPaCa-2 human pancreatic tumor cells and L929 murine fibroblasts were loaded with iron-oxide magnetic nanoparticles (MNP) and exposed to MFH for either 30 min or 90 min. The resulting cytotoxic effects were assessed via clonogenic assay. Our results demonstrate that cell damage depends not only on the obvious parameters bulk temperature and duration of treatment, but most importantly on cell type and thermal energy deposited per cell during MFH treatment. Tumor cell death of 95\% was achieved by depositing an intracellular total thermal energy with about 50\% margin to damage of healthy cells. This is attributed to combined intracellular nanoheating and extracellular bulk heating. Tumor cell damage of up to 86\% was observed for MFH treatment without perceptible bulk temperature rise. Effective heating decreased by up to 65\% after MNP were internalized inside cells.}, language = {en} } @article{EngelmannBuhlDraacketal.2018, author = {Engelmann, Ulrich M. and Buhl, Eva Miriam and Draack, Sebastian and Viereck, Thilo and Frank, and Schmitz-Rode, Thomas and Slabu, Ioana}, title = {Magnetic relaxation of agglomerated and immobilized iron oxide nanoparticles for hyperthermia and imaging applications}, series = {IEEE Magnetic Letters}, volume = {9}, journal = {IEEE Magnetic Letters}, number = {Article number 8519617}, publisher = {IEEE}, address = {New York, NY}, issn = {1949-307X}, doi = {10.1109/LMAG.2018.2879034}, year = {2018}, abstract = {Magnetic nanoparticles (MNPs) are used as therapeutic and diagnostic agents for local delivery of heat and image contrast enhancement in diseased tissue. Besides magnetization, the most important parameter that determines their performance for these applications is their magnetic relaxation, which can be affected when MNPs immobilize and agglomerate inside tissues. In this letter, we investigate different MNP agglomeration states for their magnetic relaxation properties under excitation in alternating fields and relate this to their heating efficiency and imaging properties. With focus on magnetic fluid hyperthermia, two different trends in MNP heating efficiency are measured: an increase by up to 23\% for agglomerated MNP in suspension and a decrease by up to 28\% for mixed states of agglomerated and immobilized MNP, which indicates that immobilization is the dominant effect. The same comparatively moderate effects are obtained for the signal amplitude in magnetic particle spectroscopy.}, language = {en} } @article{EngelmannBuhlBaumannetal.2017, author = {Engelmann, Ulrich M. and Buhl, Eva Miriam and Baumann, Martin and Schmitz-Rode, Thomas and Slabu, Ioana}, title = {Agglomeration of magnetic nanoparticles and its effects on magnetic hyperthermia}, series = {Current Directions in Biomedical Engineering}, volume = {3}, journal = {Current Directions in Biomedical Engineering}, number = {2}, publisher = {De Gruyter}, address = {Berlin}, issn = {2364-5504}, doi = {10.1515/cdbme-2017-0096}, pages = {457 -- 460}, year = {2017}, language = {en} }