@article{KuehnHaugnerStaatetal.2004, author = {K{\"u}hn, Raoul-Roman and Haugner, Werner and Staat, Manfred and Sponagel, Stefan}, title = {A Two Phase Mixture Model based on Bone Observation}, year = {2004}, abstract = {An optimization method is developed to describe the mechanical behaviour of the human cancellous bone. The method is based on a mixture theory. A careful observation of the behaviour of the bone material leads to the hypothesis that the bone density is controlled by the principal stress trajectories (Wolff's law). The basic idea of the developed method is the coupling of a scalar value via an eigenvalue problem to the principal stress trajectories. On the one hand this theory will permit a prediction of the reaction of the biological bone structure after the implantation of a prosthesis, on the other hand it may be useful in engineering optimization problems. An analytical example shows its efficiency.}, subject = {Knochen}, language = {en} } @article{BaeckerBegingBisellietal.2009, author = {B{\"a}cker, Matthias and Beging, Stefan and Biselli, Manfred and Poghossian, Arshak and Wang, J. and Zang, Werner and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Concept for a solid-state multi-parameter sensor system for cell-culture monitoring}, series = {Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI}, journal = {Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {0013-4686}, pages = {6107 -- 6112}, year = {2009}, language = {en} } @article{WagnerBegingRotteretal.2007, author = {Wagner, Torsten and Beging, Stefan and Rotter, L. and Poghossian, Arshak and Biselli, Manfred and Zang, Werner and Sch{\"o}ning, Michael Josef}, title = {Online-Messsysteme f{\"u}r die automatisierte Charakterisierung von feldeffektbasierten Biosensoren}, series = {8. Dresdner Sensor-Symposium : Sensoren f{\"u}r Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme f{\"u}r die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung f{\"u}r die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.)}, journal = {8. Dresdner Sensor-Symposium : Sensoren f{\"u}r Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme f{\"u}r die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung f{\"u}r die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.)}, publisher = {TUDpress, Verl. der Wissenschaften}, address = {Dresden}, isbn = {978-3-940046-45-1}, pages = {257 -- 260}, year = {2007}, language = {de} } @article{WendlandtKochBritzetal.2023, author = {Wendlandt, Tim and Koch, Claudia and Britz, Beate and Liedek, Anke and Schmidt, Nora and Werner, Stefan and Gleba, Yuri and Vahidpour, Farnoosh and Welden, Melanie and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Facile Purification and Use of Tobamoviral Nanocarriers for Antibody-Mediated Display of a Two-Enzyme System}, series = {Viruses}, volume = {9}, journal = {Viruses}, number = {15}, publisher = {MDPI}, address = {Basel}, issn = {1999-4915}, doi = {doi.org/10.3390/v15091951}, pages = {Artikel 1951}, year = {2023}, abstract = {Immunosorbent turnip vein clearing virus (TVCV) particles displaying the IgG-binding domains D and E of Staphylococcus aureus protein A (PA) on every coat protein (CP) subunit (TVCVPA) were purified from plants via optimized and new protocols. The latter used polyethylene glycol (PEG) raw precipitates, from which virions were selectively re-solubilized in reverse PEG concentration gradients. This procedure improved the integrity of both TVCVPA and the wild-type subgroup 3 tobamovirus. TVCVPA could be loaded with more than 500 IgGs per virion, which mediated the immunocapture of fluorescent dyes, GFP, and active enzymes. Bi-enzyme ensembles of cooperating glucose oxidase and horseradish peroxidase were tethered together on the TVCVPA carriers via a single antibody type, with one enzyme conjugated chemically to its Fc region, and the other one bound as a target, yielding synthetic multi-enzyme complexes. In microtiter plates, the TVCVPA-displayed sugar-sensing system possessed a considerably increased reusability upon repeated testing, compared to the IgG-bound enzyme pair in the absence of the virus. A high coverage of the viral adapters was also achieved on Ta2O5 sensor chip surfaces coated with a polyelectrolyte interlayer, as a prerequisite for durable TVCVPA-assisted electrochemical biosensing via modularly IgG-assembled sensor enzymes.}, language = {en} } @incollection{HirtBleckBobzinetal.2011, author = {Hirt, Gerhard and Bleck, Wolfgang and Bobzin, Kirsten and Schleser, Markus and Brecher, Christian and B{\"u}hrig-Polazcek, Andreas and Haberstroh, Edmund and Klocke, Fritz and Loosen, Peter and Michaeli, Walter and Poprawe, Reinhart and Reisgen, Uwe and Arntz, Kristian and Bagcivan, Nazlim and Bambach, Markus and B{\"a}umler, Stephan and Beckemper, Stefan and Bergweiler, Georg and Breitbach, Tobias and Buchholz, Steffen and B{\"u}ltmann, Jan and Diettrich, J{\"o}rg and Do-Khac, Dennis and Eilbracht, Stephan and Emonts, Michael and Flock, Dustin and Gerhardt, Kai and Gillner, Arnold and G{\"o}ttmann, Alexander and Gr{\"o}nlund, Oliver and Hartmann, Claudia and Heinen, Daniel and Herfs, Werner and Hermani, Jan-Patrick and Holtkamp, Jens and Todor, Ivanov and Jakob, Matthias and Janssen, Andreas and Karlberger, Andreas and Klaiber, Fritz and Kutschmann, Pia and Neuß, Andreas and Prahl, Ulrich and Roderburg, Andreas and Rosen, Chris-J{\"o}rg and R{\"o}sner, Andreas and Saeed-Akbari, Alireza and Scharf, Micha and Scheik, Sven and Schleser, Markus and Sch{\"o}ngart, Maximilian and Stein, Lars and Steiners, Marius and Stollenwerk, Jochen and Araghi, Babak Taleb and Theiß, Sebastian and Wunderle, Johannes}, title = {Hybride Produktionssysteme}, series = {Integrative Produktionstechnik f{\"u}r Hochlohnl{\"a}nder / hrsg. von Christian Brecher}, booktitle = {Integrative Produktionstechnik f{\"u}r Hochlohnl{\"a}nder / hrsg. von Christian Brecher}, publisher = {Springer}, address = {Berlin [u.a.]}, isbn = {978-3-642-20692-4 (Print) ; 978-3-642-20693-1 (E-Book)}, doi = {10.1007/978-3-642-20693-1_5}, pages = {465 -- 745}, year = {2011}, abstract = {W{\"a}hrend die virtuelle Produktentstehungskette große Gestaltungsfreir{\"a}ume bietet, ist die reale Produktentstehungskette durch wesentlich mehr Randbedingungen gekennzeichnet, die nicht oder nur ansatzweise beeinflussbar sind. Die Realisierung des aus logistischer Sicht optimalen One-Piece-Flow bei gleichzeitiger Steigerung von Flexibilit{\"a}t und Produktivit{\"a}t sowie des Verschiebens der Grenze des technologisch Machbaren m{\"u}ssen in zuk{\"u}nftigen Forschungsans{\"a}tzen gleichermaßen betrachtet werden. Die Grenzverschiebung auf Basis der Integration von Technologien ist dabei ein viel versprechender Ansatz, der es in vielen F{\"a}llen erm{\"o}glicht, in allen genannten Zielrichtungen gleichermaßen Potentiale zu erschließen.}, language = {de} }