@book{KnepperPfeiffer1998, author = {Knepper, Ludger and Pfeiffer, Johann}, title = {Diplom-Ingenieur/Diplom-Ingenieurin (Fachhochschule) Maschinenbau Konstruktionstechnik}, publisher = {Bertelsmann}, address = {Bielefeld}, pages = {Loseblattausg.}, year = {1998}, language = {de} } @book{KnepperPfeiffer1999, author = {Knepper, Ludger and Pfeiffer, Johann}, title = {Diplom-Ingenieur / Diplom-Ingenieurin (Fachhochschule) Maschinenbau, Energie- und W{\"a}rmetechnik}, publisher = {Bertelsmann}, address = {Bielefeld}, pages = {Loseblattausg.}, year = {1999}, language = {de} } @article{KnoedlerRuehlEmontsetal.2019, author = {Kn{\"o}dler, Matthias and R{\"u}hl, Clemens and Emonts, Jessica and Buyel, Johannes Felix}, title = {Seasonal weather changes affect the yield and quality of recombinant proteins produced in transgenic tobacco plants in a greenhouse setting}, series = {Frontiers in Plant Science}, journal = {Frontiers in Plant Science}, number = {10}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {1664-462X (online-ressource)}, doi = {10.3389/fpls.2019.01245}, pages = {13 Seiten}, year = {2019}, abstract = {Transgenic plants have the potential to produce recombinant proteins on an agricultural scale, with yields of several tons per year. The cost-effectiveness of transgenic plants increases if simple cultivation facilities such as greenhouses can be used for production. In such a setting, we expressed a novel affinity ligand based on the fluorescent protein DsRed, which we used as a carrier for the linear epitope ELDKWA from the HIV-neutralizing antibody 2F5. The DsRed-2F5-epitope (DFE) fusion protein was produced in 12 consecutive batches of transgenic tobacco (Nicotiana tabacum) plants over the course of 2 years and was purified using a combination of blanching and immobilized metal-ion affinity chromatography (IMAC). The average purity after IMAC was 57 ± 26\% (n = 24) in terms of total soluble protein, but the average yield of pure DFE (12 mg kg-1) showed substantial variation (± 97 mg kg-1, n = 24) which correlated with seasonal changes. Specifically, we found that temperature peaks (>28°C) and intense illuminance (>45 klx h-1) were associated with lower DFE yields after purification, reflecting the loss of the epitope-containing C-terminus in up to 90\% of the product. Whereas the weather factors were of limited use to predict product yields of individual harvests conducted for each batch (spaced by 1 week), the average batch yields were well approximated by simple linear regression models using two independent variables for prediction (illuminance and plant age). Interestingly, accumulation levels determined by fluorescence analysis were not affected by weather conditions but positively correlated with plant age, suggesting that the product was still expressed at high levels, but the extreme conditions affected its stability, albeit still preserving the fluorophore function. The efficient production of intact recombinant proteins in plants may therefore require adequate climate control and shading in greenhouses or even cultivation in fully controlled indoor farms.}, language = {en} } @inproceedings{KolkmannGriesSchleseretal.2005, author = {Kolkmann, Annette and Gries, Thomas and Schleser, Markus and Dilthey, Ulrich}, title = {Innovative yarn structures and coatings for textile reinforced concrete}, series = {All lectures / Techtextil Symposium : 6. - 9. 6.2005, Frankfurt am Main}, booktitle = {All lectures / Techtextil Symposium : 6. - 9. 6.2005, Frankfurt am Main}, address = {Frankfurt a.M.}, pages = {1 CD-ROM}, year = {2005}, language = {en} } @article{KosterScheidweilerTieves2016, author = {Koster, Arie and Scheidweiler, Robert and Tieves, Martin}, title = {A flow based pruning scheme for enumerative equitable coloring algorithms}, series = {A flow based pruning scheme for enumerative equitable coloring algorithms}, journal = {A flow based pruning scheme for enumerative equitable coloring algorithms}, doi = {10.48550/arXiv.1607.08754}, pages = {1 -- 30}, year = {2016}, abstract = {An equitable graph coloring is a proper vertex coloring of a graph G where the sizes of the color classes differ by at most one. The equitable chromatic number is the smallest number k such that G admits such equitable k-coloring. We focus on enumerative algorithms for the computation of the equitable coloring number and propose a general scheme to derive pruning rules for them: We show how the extendability of a partial coloring into an equitable coloring can be modeled via network flows. Thus, we obtain pruning rules which can be checked via flow algorithms. Computational experiments show that the search tree of enumerative algorithms can be significantly reduced in size by these rules and, in most instances, such naive approach even yields a faster algorithm. Moreover, the stability, i.e., the number of solved instances within a given time limit, is greatly improved. Since the execution of flow algorithms at each node of a search tree is time consuming, we derive arithmetic pruning rules (generalized Hall-conditions) from the network model. Adding these rules to an enumerative algorithm yields an even larger runtime improvement.}, language = {en} } @article{KunkelGebhardtMpofuetal.2018, author = {Kunkel, Maximilian Hugo and Gebhardt, Andreas and Mpofu, Khumbaulani and Kallweit, Stephan}, title = {Statistical assessment of mechanical properties of selective laser melted specimens of stainless steel}, series = {The International Journal of Advanced Manufacturing Technology}, volume = {98}, journal = {The International Journal of Advanced Manufacturing Technology}, number = {5-8}, publisher = {Springer}, address = {London}, issn = {0268-3768}, doi = {10.1007/s00170-018-2040-8}, pages = {1409 -- 1431}, year = {2018}, abstract = {The rail business is challenged by long product life cycles and a broad spectrum of assembly groups and single parts. When spare part obsolescence occurs, quick solutions are needed. A reproduction of obsolete parts is often connected to long waiting times and minimum lot quantities that need to be purchased and stored. Spare part storage is therefore challenged by growing stocks, bound capital and issues of part ageing. A possible solution could be a virtual storage of spare parts which will be 3D printed through additive manufacturing technologies in case of sudden demand. As mechanical properties of additive manufactured parts are neither guaranteed by machine manufacturers nor by service providers, the utilization of this relatively young technology is impeded and research is required to address these issues. This paper presents an examination of mechanical properties of specimens manufactured from stainless steel through the selective laser melting (SLM) process. The specimens were produced in multiple batches. This paper interrogates the question if the test results follow a normal distribution pattern and if mechanical property predictions can be made. The results will be put opposite existing threshold values provided as the industrial standard. Furthermore, probability predictions will be made in order to examine the potential of the SLM process to maintain state-of-the-art mechanical property requirements.}, language = {en} } @article{KunkelGebhardtMpofuetal.2019, author = {Kunkel, Maximilian Hugo and Gebhardt, Andreas and Mpofu, Khumbulani and Kallweit, Stephan}, title = {Quality assurance in metal powder bed fusion via deep-learning-based image classification}, series = {Rapid Prototyping Journal}, volume = {26}, journal = {Rapid Prototyping Journal}, number = {2}, issn = {1355-2546}, doi = {10.1108/RPJ-03-2019-0066}, pages = {259 -- 266}, year = {2019}, language = {en} } @article{Kaemper1996, author = {K{\"a}mper, Klaus-Peter}, title = {Development of low-cost injection moulded micropumps. Entwicklung von kosteng{\"u}nstigen, mittels Spritzguß hergestellten Mikropumpen / D{\"o}pper, J. (u.a.)}, series = {Actuator 96 : Conference Proceedings ; 5th International Conference on New Actuators ; 26- 28 June, Bremen, Germany / Ed.: Hubert Borgmann. Publ. by: AXON Technology Consult GmbH}, journal = {Actuator 96 : Conference Proceedings ; 5th International Conference on New Actuators ; 26- 28 June, Bremen, Germany / Ed.: Hubert Borgmann. Publ. by: AXON Technology Consult GmbH}, address = {Bremen}, pages = {37 -- 40}, year = {1996}, language = {en} } @article{Kaemper2002, author = {K{\"a}mper, Klaus-Peter}, title = {Die Mikroaktorik wird erwachsen}, series = {INNO : innovative Technik - neue Anwendungen / Hrsg.: IVAM Fachverband f{\"u}r Mikrotechnik, Dortmund. Ausgabe 22 (2002)}, journal = {INNO : innovative Technik - neue Anwendungen / Hrsg.: IVAM Fachverband f{\"u}r Mikrotechnik, Dortmund. Ausgabe 22 (2002)}, pages = {4 -- 5}, year = {2002}, language = {de} } @article{Kaemper1996, author = {K{\"a}mper, Klaus-Peter}, title = {Mikromontage zur Fertigung hybrider Mikrosysteme. Nienhaus, M.; Berg, U.; Ehrfeld, W.; K{\"a}mper, K.-P.; Lehr, H.; Michel, F.}, series = {41. Internationales Wissenschaftliches Kolloquium, Wandel im Maschinenbau durch Feinwerktechik und Mikrosystemtechnik, Bd. 1, Ilmenau, DE, 23.-26. Sep, 1996}, journal = {41. Internationales Wissenschaftliches Kolloquium, Wandel im Maschinenbau durch Feinwerktechik und Mikrosystemtechnik, Bd. 1, Ilmenau, DE, 23.-26. Sep, 1996}, pages = {121 -- 126}, year = {1996}, language = {de} }