@article{HonarvarfardGamellaPoghossianetal.2017,
  author    = {Honarvarfard, Elham and Gamella, Maria and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Katz, Evgeny},
  title     = {An enzyme-based reversible Controlled NOT (CNOT) logic gate operating on a semiconductor transducer},
  series = {Applied Materials Today},
  volume    = {9},
  journal   = {Applied Materials Today},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2352-9407},
  doi       = {10.1016/j.apmt.2017.08.003},
  pages     = {266 -- 270},
  year      = {2017},
  abstract  = {An enzyme-based biocatalytic system mimicking operation of a logically reversible Controlled NOT (CNOT) gate has been interfaced with semiconductor electronic transducers. Electrolyte-insulator-semiconductor (EIS) structures have been used to transduce chemical changes produced by the enzyme system to an electronically readable capacitive output signal using field-effect features of the EIS device. Two enzymes, urease and esterase, were immobilized on the insulating interface of EIS structure producing local pH changes performing XOR logic operation controlled by various combinations of the input signals represented by urea and ethyl butyrate. Another EIS transducer was functionalized with esterase only, thus performing Identity (ID) logic operation for the ethyl butyrate input. Both semiconductor devices assembled in parallel operated as a logically reversible CNOT gate. The present system, despite its simplicity, demonstrated for the first time logically reversible function of the enzyme system transduced electronically with the semiconductor devices. The biomolecular realization of a CNOT gate interfaced with semiconductors is promising for integration into complex biomolecular networks and future biosensor/biomedical applications.},
  language  = {en}
}
@article{GossmannThomasHorvathetal.2020,
  author    = {Gossmann, Matthias and Thomas, Ulrich and Horv{\´a}th, Andr{\´a}s and Dragicevic, Elena and Stoelzle-Feix, Sonja and Jung, Alexander and Raman, Aravind Hariharan and Staat, Manfred and Linder, Peter},
  title     = {A higher-throughput approach to investigate cardiac contractility in vitro under physiological mechanical conditions},
  series = {Journal of Pharmacological and Toxicological Methods},
  volume    = {105},
  journal   = {Journal of Pharmacological and Toxicological Methods},
  number    = {Article 106843},
  publisher = {Elsevier},
  address   = {New York, NY},
  doi       = {10.1016/j.vascn.2020.106843},
  year      = {2020},
  language  = {en}
}
@article{LinderBecklerDoerretal.2019,
  author    = {Linder, Peter and Beckler, Matthias and Doerr, Leo and Stoelzle-Feix, Sonja and Fertig, Niels and Jung, Alexander and Staat, Manfred and Gossmann, Matthias},
  title     = {A new in vitro tool to investigate cardiac contractility under physiological mechanical conditions},
  series = {Journal of Pharmacological and Toxicological Methods},
  volume    = {99},
  journal   = {Journal of Pharmacological and Toxicological Methods},
  number    = {Article number 106595},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1056-8719},
  doi       = {10.1016/j.vascn.2019.05.162},
  year      = {2019},
  language  = {en}
}
@article{HuckJollyWagneretal.2011,
  author    = {Huck, Christina and Jolly, Christina and Wagner, Patrick and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {One-chip integrated dual amperometric/field-effect sensor for the detection of dissolved hydrogen},
  series = {Procedia Engineering. 25 (2011)},
  journal   = {Procedia Engineering. 25 (2011)},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {1877-7058},
  pages     = {1161 -- 1164},
  year      = {2011},
  language  = {en}
}
@article{OezsoyluKizildagSchoeningetal.2020,
  author    = {{\"O}zsoylu, Dua and Kizildag, Sefa and Sch{\"o}ning, Michael Josef and Wagner, Torsten},
  title     = {Differential chemical imaging of extracellular acidification within microfluidic channels using a plasma-functionalized light-addressable potentiometric sensor (LAPS)},
  series = {Physics in Medicine},
  volume    = {10},
  journal   = {Physics in Medicine},
  number    = {100030},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2352-4510},
  doi       = {10.1016/j.phmed.2020.100030},
  pages     = {8},
  year      = {2020},
  abstract  = {Extracellular acidification is a basic indicator for alterations in two vital metabolic pathways: glycolysis and cellular respiration. Measuring these alterations by monitoring extracellular acidification using cell-based biosensors such as LAPS plays an important role in studying these pathways whose disorders are associated with numerous diseases including cancer. However, the surface of the biosensors must be specially tailored to ensure high cell compatibility so that cells can represent more in vivo-like behavior, which is critical to gain more realistic in vitro results from the analyses, e.g., drug discovery experiments. In this work, O2 plasma patterning on the LAPS surface is studied to enhance surface features of the sensor chip, e.g., wettability and biofunctionality. The surface treated with O2 plasma for 30 s exhibits enhanced cytocompatibility for adherent CHO-K1 cells, which promotes cell spreading and proliferation. The plasma-modified LAPS chip is then integrated into a microfluidic system, which provides two identical channels to facilitate differential measurements of the extracellular acidification of CHO-K1 cells. To the best of our knowledge, it is the first time that extracellular acidification within microfluidic channels is quantitatively visualized as differential (bio-)chemical images.},
  language  = {en}
}
@article{EngelmannPourshahidiShalabyetal.2022,
  author    = {Engelmann, Ulrich M. and Pourshahidi, Mohammad Ali and Shalaby, Ahmed and Krause, Hans-Joachim},
  title     = {Probing particle size dependency of frequency mixing magnetic detection with dynamic relaxation simulation},
  series = {Journal of Magnetism and Magnetic Materials},
  volume    = {563},
  journal   = {Journal of Magnetism and Magnetic Materials},
  number    = {In progress, Art. No. 169965},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0304-8853},
  doi       = {10.1016/j.jmmm.2022.169965},
  year      = {2022},
  abstract  = {Biomedical applications of magnetic nanoparticles (MNP) fundamentally rely on the particles' magnetic relaxation as a response to an alternating magnetic field. The magnetic relaxation complexly depends on the interplay of MNP magnetic and physical properties with the applied field parameters. It is commonly accepted that particle core size is a major contributor to signal generation in all the above applications, however, most MNP samples comprise broad distribution spanning nm and more. Therefore, precise knowledge of the exact contribution of individual core sizes to signal generation is desired for optimal MNP design generally for each application. Specifically, we present a magnetic relaxation simulation-driven analysis of experimental frequency mixing magnetic detection (FMMD) for biosensing to quantify the contributions of individual core size fractions towards signal generation. Applying our method to two different experimental MNP systems, we found the most dominant contributions from approx. 20 nm sized particles in the two independent MNP systems. Additional comparison between freely suspended and immobilized MNP also reveals insight in the MNP microstructure, allowing to use FMMD for MNP characterization, as well as to further fine-tune its applicability in biosensing.},
  language  = {en}
}
@article{ZhenLiangStaatetal.2024,
  author    = {Zhen, Manghao and Liang, Yunpei and Staat, Manfred and Li, Quanqui and Li, Jianbo},
  title     = {Discontinuous fracture behaviors and constitutive model of sandstone specimens containing non-parallel prefabricated fissures under uniaxial compression},
  series = {Theoretical and Applied Fracture Mechanics},
  volume    = {131},
  journal   = {Theoretical and Applied Fracture Mechanics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0167-8442},
  doi       = {10.1016/j.tafmec.2024.104373},
  pages     = {Artikel 104373},
  year      = {2024},
  abstract  = {The deformation and damage laws of non-homogeneous irregular structural planes in rocks are the basis for studying the stability of rock engineering. To investigate the damage characteristics of rock containing non-parallel fissures, uniaxial compression tests and numerical simulations were conducted on sandstone specimens containing three non-parallel fissures inclined at 0°, 45° and 90° in this study. The characteristics of crack initiation and crack evolution of fissures with different inclinations were analyzed. A constitutive model for the discontinuous fractures of fissured sandstone was proposed. The results show that the fracture behaviors of fissured sandstone specimens are discontinuous. The stress-strain curves are non-smooth and can be divided into nonlinear crack closure stage, linear elastic stage, plastic stage and brittle failure stage, of which the plastic stage contains discontinuous stress drops. During the uniaxial compression test, the middle or ends of 0° fissures were the first to crack compared to 45° and 90° fissures. The end with small distance between 0° and 45° fissures cracked first, and the end with large distance cracked later. After the final failure, 0° fissures in all specimens were fractured, while 45° and 90° fissures were not necessarily fractured. Numerical simulation results show that the concentration of compressive stress at the tips of 0°, 45° and 90° fissures, as well as the concentration of tensile stress on both sides, decreased with the increase of the inclination angle. A constitutive model for the discontinuous fractures of fissured sandstone specimens was derived by combining the logistic model and damage mechanic theory. This model can well describe the discontinuous drops of stress and agrees well with the whole processes of the stress-strain curves of the fissured sandstone specimens.},
  language  = {en}
}
@article{DiktaReisselHarlass2016,
  author    = {Dikta, Gerhard and Reißel, Martin and Harlaß, Carsten},
  title     = {Semi-parametric survival function estimators deduced from an identifying Volterra type integral equation},
  series = {Journal of multivariate analysis},
  journal   = {Journal of multivariate analysis},
  number    = {147},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.jmva.2016.02.008},
  pages     = {273 -- 284},
  year      = {2016},
  abstract  = {Based on an identifying Volterra type integral equation for randomly right censored observations from a lifetime distribution function F, we solve the corresponding estimating equation by an explicit and implicit Euler scheme. While the first approach results in some known estimators, the second one produces new semi-parametric and pre-smoothed Kaplan-Meier estimators which are real distribution functions rather than sub-distribution functions as the former ones are. This property of the new estimators is particular useful if one wants to estimate the expected lifetime restricted to the support of the observation time. Specifically, we focus on estimation under the semi-parametric random censorship model (SRCM), that is, a random censorship model where the conditional expectation of the censoring indicator given the observation belongs to a parametric family. We show that some estimated linear functionals which are based on the new semi-parametric estimator are strong consistent, asymptotically normal, and efficient under SRCM. In a small simulation study, the performance of the new estimator is illustrated under moderate sample sizes. Finally, we apply the new estimator to a well-known real dataset.},
  language  = {en}
}
@article{MichaelMayerWeberetal.2017,
  author    = {Michael, Hackl and Mayer, Katharina and Weber, Mareike and Staat, Manfred and van Riet, Roger and Burkhart, Klau Josef and M{\"u}ller, Lars Peter and Wegmann, Kilian},
  title     = {Plate osteosynthesis of proximal ulna fractures : a biomechanical micromotion analysis},
  series = {The journal of hand surgery},
  volume    = {42},
  journal   = {The journal of hand surgery},
  number    = {10},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0363-5023},
  doi       = {10.1016/j.jhsa.2017.05.014},
  pages     = {834.e1 -- 834.e7},
  year      = {2017},
  language  = {en}
}
@article{RhodenBallGrajewskietal.2023,
  author    = {Rhoden, Imke and Ball, Christopher Stephen and Grajewski, Matthias and Kuckshinrich, Wilhelm},
  title     = {Reverse engineering of stakeholder preferences - A multi-criteria assessment of the German passenger car sector},
  series = {Renewable and Sustainable Energy Reviews},
  volume    = {181},
  journal   = {Renewable and Sustainable Energy Reviews},
  number    = {July 2023},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1364-0321},
  doi       = {10.1016/j.rser.2023.113352},
  pages     = {Article number: 113352},
  year      = {2023},
  abstract  = {Germany is a frontrunner in setting frameworks for the transition to a low-carbon system. The mobility sector plays a significant role in this shift, affecting different people and groups on multiple levels. Without acceptance from these stakeholders, emission targets are out of reach. This research analyzes how the heterogeneous preferences of various stakeholders align with the transformation of the mobility sector, looking at the extent to which the German transformation paths are supported and where stakeholders are located. Under the research objective of comparing stakeholders' preferences to identify which car segments require additional support for a successful climate transition, a status quo of stakeholders and car performance criteria is the foundation for the analysis. Stakeholders' hidden preferences hinder the derivation of criteria weightings from stakeholders; therefore, a ranking from observed preferences is used. This study's inverse multi-criteria decision analysis means that weightings can be predicted and used together with a recalibrated performance matrix to explore future preferences toward car segments. Results show that stakeholders prefer medium-sized cars, with the trend pointing towards the increased potential for alternative propulsion technologies and electrified vehicles. These insights can guide the improved targeting of policy supporting the energy and mobility transformation. Additionally, the method proposed in this work can fully handle subjective approaches while incorporating a priori information. A software implementation of the proposed method completes this work and is made publicly available.},
  language  = {en}
}
@article{Gaigall2020,
  author    = {Gaigall, Daniel},
  title     = {Rothman-Woodroofe symmetry test statistic revisited},
  series = {Computational Statistics \& Data Analysis},
  volume    = {2020},
  journal   = {Computational Statistics \& Data Analysis},
  number    = {142},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0167-9473},
  doi       = {10.1016/j.csda.2019.106837},
  pages     = {Artikel 106837},
  year      = {2020},
  abstract  = {The Rothman-Woodroofe symmetry test statistic is revisited on the basis of independent but not necessarily identically distributed random variables. The distribution-freeness if the underlying distributions are all symmetric and continuous is obtained. The results are applied for testing symmetry in a meta-analysis random effects model. The consistency of the procedure is discussed in this situation as well. A comparison with an alternative proposal from the literature is conducted via simulations. Real data are analyzed to demonstrate how the new approach works in practice.},
  language  = {en}
}
@article{FrotscherMuanghongDursunetal.2016,
  author    = {Frotscher, Ralf and Muanghong, Danita and Dursun, G{\"o}zde and Goßmann, Matthias and Temiz Artmann, Ayseg{\"u}l and Staat, Manfred},
  title     = {Sample-specific adaption of an improved electro-mechanical model of in vitro cardiac tissue},
  series = {Journal of Biomechanics},
  volume    = {49},
  journal   = {Journal of Biomechanics},
  number    = {12},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0021-9290 (Print)},
  doi       = {10.1016/j.jbiomech.2016.01.039},
  pages     = {2428 -- 2435},
  year      = {2016},
  abstract  = {We present an electromechanically coupled computational model for the investigation of a thin cardiac tissue construct consisting of human-induced pluripotent stem cell-derived atrial, ventricular and sinoatrial cardiomyocytes. The mechanical and electrophysiological parts of the finite element model, as well as their coupling are explained in detail. The model is implemented in the open source finite element code Code_Aster and is employed for the simulation of a thin circular membrane deflected by a monolayer of autonomously beating, circular, thin cardiac tissue. Two cardio-active drugs, S-Bay K8644 and veratridine, are applied in experiments and simulations and are investigated with respect to their chronotropic effects on the tissue. These results demonstrate the potential of coupled micro- and macroscopic electromechanical models of cardiac tissue to be adapted to experimental results at the cellular level. Further model improvements are discussed taking into account experimentally measurable quantities that can easily be extracted from the obtained experimental results. The goal is to estimate the potential to adapt the presented model to sample specific cell cultures.},
  language  = {en}
}
@article{JungMuellerStaat2019,
  author    = {Jung, Alexander and M{\"u}ller, Wolfram and Staat, Manfred},
  title     = {Optimization of the flight technique in ski jumping: the influence of wind},
  number    = {Early view},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.jbiomech.2019.03.023},
  year      = {2019},
  language  = {en}
}
@article{HorbachDuongStaat2017,
  author    = {Horbach, Andreas and Duong, Minh Tuan and Staat, Manfred},
  title     = {Modelling of compressible and orthotropic surgical mesh implants based on optical deformation measurement},
  series = {Journal of the mechanical behavior of biomedical materials},
  volume    = {74},
  journal   = {Journal of the mechanical behavior of biomedical materials},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1751-6161},
  doi       = {10.1016/j.jmbbm.2017.06.012},
  pages     = {400 -- 410},
  year      = {2017},
  language  = {en}
}
@article{GrajewskiKoesterTurek2010,
  author    = {Grajewski, Matthias and K{\"o}ster, Michael and Turek, Stefam},
  title     = {Numerical analysis and implementational aspects of a new multilevel grid deformation method},
  series = {Applied Numerical Mathematics},
  volume    = {60},
  journal   = {Applied Numerical Mathematics},
  number    = {8},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0168-9274},
  doi       = {10.1016/j.apnum.2010.03.017},
  pages     = {767 -- 781},
  year      = {2010},
  abstract  = {Recently, we introduced and mathematically analysed a new method for grid deformation (Grajewski et al., 2009) [15] we call basic deformation method (BDM) here. It generalises the method proposed by Liao et al. (Bochev et al., 1996; Cai et al., 2004; Liao and Anderson, 1992) [4], [6], [20]. In this article, we employ the BDM as core of a new multilevel deformation method (MDM) which leads to vast improvements regarding robustness, accuracy and speed. We achieve this by splitting up the deformation process in a sequence of easier subproblems and by exploiting grid hierarchy. Being of optimal asymptotic complexity, we experience speed-ups up to a factor of 15 in our test cases compared to the BDM. This gives our MDM the potential for tackling large grids and time-dependent problems, where possibly the grid must be dynamically deformed once per time step according to the user's needs. Moreover, we elaborate on implementational aspects, in particular efficient grid searching, which is a key ingredient of the BDM.},
  language  = {en}
}
@article{StaatVu2012,
  author    = {Staat, Manfred and Vu, Duc Khoi},
  title     = {Limit analysis of flaws in pressurized pipes and cylindrical vessels Part II: Circumferential defects},
  series = {Engineering Fracture Mechanics ; 97(2013), H. 1},
  volume    = {97},
  journal   = {Engineering Fracture Mechanics ; 97(2013), H. 1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0013-7944},
  doi       = {10.1016/j.engfracmech.2012.05.017},
  pages     = {314 -- 333},
  year      = {2012},
  abstract  = {Upper and lower bound theorems of limit analyses have been presented in part I of the paper. Part II starts with the finite element discretization of these theorems and demonstrates how both can be combined in a primal-dual optimization problem. This recently proposed numerical method is used to guide the development of a new class of closed-form limit loads for circumferential defects, which show that only large defects contribute to plastic collapse with a rapid loss of strength with increasing crack sizes. The formulae are compared with primal-dual FEM limit analyses and with burst tests. Even closer predictions are obtained with iterative limit load solutions for the von Mises yield function and for the Tresca yield function. Pressure loading of the faces of interior cracks in thick pipes reduces the collapse load of circumferential defects more than for axial flaws. Axial defects have been treated in part I of the paper.},
  language  = {en}
}
@article{PourshahidiEngelmannOffenhaeusseretal.2022,
  author    = {Pourshahidi, Ali Mohammad and Engelmann, Ulrich M. and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim},
  title     = {Resolving ambiguities in core size determination of magnetic nanoparticles from magnetic frequency mixing data},
  series = {Journal of Magnetism and Magnetic Materials},
  volume    = {563},
  journal   = {Journal of Magnetism and Magnetic Materials},
  number    = {In progress, Art. No. 169969},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0304-8853},
  doi       = {10.1016/j.jmmm.2022.169969},
  year      = {2022},
  abstract  = {Frequency mixing magnetic detection (FMMD) has been widely utilized as a measurement technique in magnetic immunoassays. It can also be used for the characterization and distinction (also known as "colourization") of different types of magnetic nanoparticles (MNPs) based on their core sizes. In a previous work, it was shown that the large particles contribute most of the FMMD signal. This leads to ambiguities in core size determination from fitting since the contribution of the small-sized particles is almost undetectable among the strong responses from the large ones. In this work, we report on how this ambiguity can be overcome by modelling the signal intensity using the Langevin model in thermodynamic equilibrium including a lognormal core size distribution fL(dc,d0,σ) fitted to experimentally measured FMMD data of immobilized MNPs. For each given median diameter d0, an ambiguous amount of best-fitting pairs of parameters distribution width σ and number of particles Np with R2 > 0.99 are extracted. By determining the samples' total iron mass, mFe, with inductively coupled plasma optical emission spectrometry (ICP-OES), we are then able to identify the one specific best-fitting pair (σ, Np) one uniquely. With this additional externally measured parameter, we resolved the ambiguity in core size distribution and determined the parameters (d0, σ, Np) directly from FMMD measurements, allowing precise MNPs sample characterization.},
  language  = {en}
}
@article{AchtsnichtSchoenenbornOffenhaeusseretal.2019,
  author    = {Achtsnicht, Stefan and Sch{\"o}nenborn, Kristina and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim},
  title     = {Measurement of the magnetophoretic velocity of different superparamagnetic beads},
  series = {Journal of Magnetism and Magnetic Materials},
  volume    = {477},
  journal   = {Journal of Magnetism and Magnetic Materials},
  number    = {1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0304-8853},
  doi       = {10.1016/j.jmmm.2018.10.066},
  pages     = {244 -- 248},
  year      = {2019},
  abstract  = {The movement of magnetic beads due to a magnetic field gradient is of great interest in different application fields. In this report we present a technique based on a magnetic tweezers setup to measure the velocity factor of magnetically actuated individual superparamagnetic beads in a fluidic environment. Several beads can be tracked simultaneously in order to gain and improve statistics. Furthermore we show our results for different beads with hydrodynamic diameters between 200 and 1000 nm from diverse manufacturers. These measurement data can, for example, be used to determine design parameters for a magnetic separation system, like maximum flow rate and minimum separation time, or to select suitable beads for fixed experimental requirements.},
  language  = {en}
}
@article{BaringhausGaigall2015,
  author    = {Baringhaus, Ludwig and Gaigall, Daniel},
  title     = {On an independence test approach to the goodness-of-fit problem},
  series = {Journal of Multivariate Analysis},
  volume    = {2015},
  journal   = {Journal of Multivariate Analysis},
  number    = {140},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0047-259X},
  doi       = {10.1016/j.jmva.2015.05.013},
  pages     = {193 -- 208},
  year      = {2015},
  abstract  = {Let X₁,…,Xₙ be independent and identically distributed random variables with distribution F. Assuming that there are measurable functions f:R²→R and g:R²→R characterizing a family F of distributions on the Borel sets of R in the way that the random variables f(X₁,X₂),g(X₁,X₂) are independent, if and only if F∈F, we propose to treat the testing problem H:F∈F,K:F∉F by applying a consistent nonparametric independence test to the bivariate sample variables (f(Xᵢ,Xⱼ),g(Xᵢ,Xⱼ)),1⩽i,j⩽n,i≠j. A parametric bootstrap procedure needed to get critical values is shown to work. The consistency of the test is discussed. The power performance of the procedure is compared with that of the classical tests of Kolmogorov-Smirnov and Cram{\´e}r-von Mises in the special cases where F is the family of gamma distributions or the family of inverse Gaussian distributions.},
  language  = {en}
}
@article{AkimbekovDigelTastambeketal.2024,
  author    = {Akimbekov, Nuraly S. and Digel, Ilya and Tastambek, Kuanysh T. and Kozhahmetova, Marzhan and Sherelkhan, Dinara K. and Tauanov, Zhandos},
  title     = {Hydrogenotrophic methanogenesis in coal-bearing environments: Methane production, carbon sequestration, and hydrogen availability},
  series = {International Journal of Hydrogen Energy},
  volume    = {52},
  journal   = {International Journal of Hydrogen Energy},
  number    = {Part D},
  publisher = {Elsevier},
  address   = {New York},
  issn      = {1879-3487 (online)},
  doi       = {10.1016/j.ijhydene.2023.09.223},
  pages     = {1264 -- 1277},
  year      = {2024},
  abstract  = {Methane is a valuable energy source helping to mitigate the growing energy demand worldwide. However, as a potent greenhouse gas, it has also gained additional attention due to its environmental impacts. The biological production of methane is performed primarily hydrogenotrophically from H2 and CO2 by methanogenic archaea. Hydrogenotrophic methanogenesis also represents a great interest with respect to carbon re-cycling and H2 storage. The most significant carbon source, extremely rich in complex organic matter for microbial degradation and biogenic methane production, is coal. Although interest in enhanced microbial coalbed methane production is continuously increasing globally, limited knowledge exists regarding the exact origins of the coalbed methane and the associated microbial communities, including hydrogenotrophic methanogens. Here, we give an overview of hydrogenotrophic methanogens in coal beds and related environments in terms of their energy production mechanisms, unique metabolic pathways, and associated ecological functions.},
  language  = {en}
}
@article{PoghossianJablonskiKochetal.2018,
  author    = {Poghossian, Arshak and Jablonski, Melanie and Koch, Claudia and Bronder, Thomas and Rolka, David and Wege, Christina and Sch{\"o}ning, Michael Josef},
  title     = {Field-effect biosensor using virus particles as scaffolds for enzyme immobilization},
  series = {Biosensors and Bioelectronics},
  volume    = {110},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2018.03.036},
  pages     = {168 -- 174},
  year      = {2018},
  abstract  = {A field-effect biosensor employing tobacco mosaic virus (TMV) particles as scaffolds for enzyme immobilization is presented. Nanotubular TMV scaffolds allow a dense immobilization of precisely positioned enzymes with retained activity. To demonstrate feasibility of this new strategy, a penicillin sensor has been developed by coupling a penicillinase with virus particles as a model system. The developed field-effect penicillin biosensor consists of an Al-p-Si-SiO₂-Ta₂O₅-TMV structure and has been electrochemically characterized in buffer solutions containing different concentrations of penicillin G. In addition, the morphology of the biosensor surface with virus particles was characterized by scanning electron microscopy and atomic force microscopy methods. The sensors possessed a high penicillin sensitivity of ~ 92 mV/dec in a nearly-linear range from 0.1 mM to 10 mM, and a low detection limit of about 50 µM. The long-term stability of the penicillin biosensor was periodically tested over a time period of about one year without any significant loss of sensitivity. The biosensor has also been successfully applied for penicillin detection in bovine milk samples.},
  language  = {en}
}
@article{IkenAhlbornGerlachetal.2013,
  author    = {Iken, Heiko and Ahlborn, Kristina and Gerlach, Frank and Vonau, Winfried and Zander, Wilhelm and Schubert, J{\"u}rgen P. and Sch{\"o}ning, Michael Josef},
  title     = {Development of redox glasses and subsequent processing by means of pulsed laser deposition for realizing silicon-based thin-film sensors},
  series = {Electrochimica acta},
  journal   = {Electrochimica acta},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-3859 (E-Journal); 0013-4686 (Print)},
  pages     = {Available online 30.8.2013},
  year      = {2013},
  language  = {en}
}
@article{BaringhausGaigall2017,
  author    = {Baringhaus, Ludwig and Gaigall, Daniel},
  title     = {Hotelling's T² tests in paired and independent survey samples: An efficiency comparison},
  series = {Journal of Multivariate Analysis},
  volume    = {2017},
  journal   = {Journal of Multivariate Analysis},
  number    = {154},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0047-259X},
  doi       = {10.1016/j.jmva.2016.11.004},
  pages     = {177 -- 198},
  year      = {2017},
  abstract  = {Hotelling's T² tests in paired and independent survey samples are compared using the traditional asymptotic efficiency concepts of Hodges-Lehmann, Bahadur and Pitman, as well as through criteria based on the volumes of corresponding confidence regions. Conditions characterizing the superiority of a procedure are given in terms of population canonical correlation type coefficients. Statistical tests for checking these conditions are developed. Test statistics based on the eigenvalues of a symmetrized sample cross-covariance matrix are suggested, as well as test statistics based on sample canonical correlation type coefficients.},
  language  = {en}
}
@article{MuribYeapEurlingsetal.2016,
  author    = {Murib, M. S. and Yeap, W. S. and Eurlings, Y. and Grinsven, B. van and Boyen, H.-G. and Conings, B. and Michiels, L. and Ameloot, Marcel and Carleer, R. and Warmer, J. and Kaul, P. and Haenen, K. and Sch{\"o}ning, Michael Josef and Ceuninck, W. de and Wagner, P.},
  title     = {Heat-transfer based characterization of DNA on synthetic sapphire chips},
  series = {Sensors and Actuators B: Chemical},
  volume    = {230},
  journal   = {Sensors and Actuators B: Chemical},
  number    = {230},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2016.02.027},
  pages     = {260 -- 271},
  year      = {2016},
  abstract  = {In this study, we show that synthetic sapphire (Al₂O₃), an established implant material, can also serve as a platform material for biosensors comparable to nanocrystalline diamond. Sapphire chips, beads, and powder were first modified with (3-aminopropyl) triethoxysilane (APTES), followed by succinic anhydride (SA), and finally single-stranded probe DNA was EDC coupled to the functionalized layer. The presence of the APTES-SA layer on sapphire powders was confirmed by thermogravimetric analyis and Fourier-transform infrared spectroscopy. Using planar sapphire chips as substrates and X-ray photoelectron spectroscopy (XPS) as surface-sensitive tool, the sequence of individual layers was analyzed with respect to their chemical state, enabling the quantification of areal densities of the involved molecular units. Fluorescence microscopy was used to demonstrate the hybridization of fluorescently tagged target DNA to the probe DNA, including denaturation- and re-hybridization experiments. Due to its high thermal conductivity, synthetic sapphire is especially suitable as a chip material for the heat-transfer method, which was employed to distinguish complementary- and non-complementary DNA duplexes containing single-nucleotide polymorphisms. These results indicate that it is possible to detect mutations electronically with a chemically resilient and electrically insulating chip material.},
  language  = {en}
}