@inproceedings{MuellerVeggianNeskakisLiederetal.1978,
  author    = {M{\"u}ller-Veggian, Mattea and Neskakis, A. and Lieder, R. M. and Beuscher, H.},
  title     = {Study of rotational aligned bands in ¹⁹⁰,¹⁹²,¹⁹⁴ Au},
  series = {Nuclear interactions : International Conference on Nuclear Interactions held in Canberra, 28 Aug. - 1 Sept. 1978 / ed. by Brian Albert Robson. - (Lecture notes in physics ; 92)},
  booktitle = {Nuclear interactions : International Conference on Nuclear Interactions held in Canberra, 28 Aug. - 1 Sept. 1978 / ed. by Brian Albert Robson. - (Lecture notes in physics ; 92)},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {978-3-540-09102-8},
  pages     = {428},
  year      = {1978},
  language  = {en}
}
@article{Dikta2006,
  author    = {Dikta, Gerhard},
  title     = {Time series methods to forecast patent filings},
  series = {Forecasting innovations : methods for predicting numbers of patent filings ; with 71 tables / Peter Hingley ; Marc Nicolas (ed.),},
  journal   = {Forecasting innovations : methods for predicting numbers of patent filings ; with 71 tables / Peter Hingley ; Marc Nicolas (ed.),},
  publisher = {Springer},
  address   = {Berlin [u.a.]},
  isbn      = {978-3-540-35991-3},
  doi       = {10.1007/3-540-35992-3_6},
  pages     = {95 -- 124},
  year      = {2006},
  language  = {en}
}
@article{PawelkeButzer1968,
  author    = {Pawelke, Siegfried and Butzer, Paul L.},
  title     = {Semi-groups and resolvent operators},
  series = {Archive for Rational Mechanics and Analysis},
  volume    = {30},
  journal   = {Archive for Rational Mechanics and Analysis},
  number    = {2},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0003-9527},
  doi       = {10.1007/BF00250941},
  pages     = {127 -- 147},
  year      = {1968},
  language  = {en}
}
@incollection{MuellerVeggianKopsQuinetal.2007,
  author    = {M{\"u}ller-Veggian, Mattea and Kops, Elena Rota and Quin, Peng and Herzog, Hans},
  title     = {MRI Based Attenuation Correction for Brain PET Images},
  series = {Advances in medical engineering / [3rd RPT - Remagener Physiktage together with the Second Scientific Workshop of Medical Robotics, Navigation and Visualization ... Remagen ... 7.-9. M{\"a}rz 2007]. Thorsten M. Buzug (ed.) Part 1.},
  booktitle = {Advances in medical engineering / [3rd RPT - Remagener Physiktage together with the Second Scientific Workshop of Medical Robotics, Navigation and Visualization ... Remagen ... 7.-9. M{\"a}rz 2007]. Thorsten M. Buzug (ed.) Part 1.},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {978-3-540-68763-4},
  doi       = {10.1007/978-3-540-68764-1_15},
  pages     = {93 -- 97},
  year      = {2007},
  abstract  = {This work describes a procedure to yield attenuation maps from MR images which are used for the absorption correction (AC) of brain PET data. Such an approach could be mandatory for future combined PET and MRI scanners, which probably do not include a transmission facility. T1-weighted MR images were segmented into brain tissue, bone, soft tissue, and sinus; attenuation coefficients corresponding to elemental composition and density as well as to 511 keV photon energy were respectively assigned. Attenuation maps containing up to four compartments were created and forward projected into sinograms with attenuation factors which then were used for AC during reconstruction of FDG-PET data. The commonly used AC based on a radioactive (68Ge) transmission scan served as reference. The reconstructed radioactivity values obtained with the MRI-based AC were about 20\% lower than those obtained with PET-based AC if the skull was not taken into account. Considering the skull the difference was still about 10\%. Our investigations demonstrate the feasibility of a MRI-based AC, but revealed also the necessity of a satisfying delineation of bone thickness which tends to be underestimated in our first approach of T1-weighted MR image segmentation.},
  language  = {en}
}
@article{Stulpe2009,
  author    = {Stulpe, Werner},
  title     = {Density Operator},
  series = {Compendium of Quantum Physics : concepts, experiments, history and philosophy / Daniel Greenberger ... ed.},
  journal   = {Compendium of Quantum Physics : concepts, experiments, history and philosophy / Daniel Greenberger ... ed.},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {978-3-540-70622-9},
  pages     = {166 -- 169},
  year      = {2009},
  language  = {en}
}
@article{DoorschodtSchreinemachersBehbahanietal.2011,
  author    = {Doorschodt, B. M. and Schreinemachers, M. C. J. M. and Behbahani, Mehdi and Florquin, S. and Weis, J. and Staat, Manfred and Tolba, R. H.},
  title     = {Hypothermic machine perfusion of kidney grafts: which pressure is preferred},
  series = {Annals of Biomedical Engineering. 39 (2011), H. 3},
  journal   = {Annals of Biomedical Engineering. 39 (2011), H. 3},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {1573-9686},
  pages     = {1051 -- 1059},
  year      = {2011},
  language  = {en}
}
@article{PaczkowskiWeissbeckerSchoeningetal.2011,
  author    = {Paczkowski, Sebastian and Weißbecker, Bernhard and Sch{\"o}ning, Michael Josef and Sch{\"u}tz, Stefan},
  title     = {Biosensors on the Basis of Insect Olfaction},
  series = {Insect biotechnology / Andreas Vilcinskas, ed.},
  journal   = {Insect biotechnology / Andreas Vilcinskas, ed.},
  publisher = {Springer},
  address   = {Dordrecht [u.a.]},
  isbn      = {978-90-481-9640-1},
  pages     = {225 -- 240},
  year      = {2011},
  language  = {en}
}
@article{KurulganDemirciDemirciTrzewiketal.2011,
  author    = {Kurulgan Demirci, Eylem and Demirci, T. and Trzewik, J{\"u}rgen and Linder, Peter and Karakulah, G. and Artmann, Gerhard and Sakizli, M. and Temiz Artmann, Ayseg{\"u}l},
  title     = {Genome-Wide Gene Expression Analysis of NIH 3T3 Cell Line Under Mechanical Stimulation},
  series = {Cellular and molecular bioengineering. 4 (2011), H. 1},
  journal   = {Cellular and molecular bioengineering. 4 (2011), H. 1},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {1865-5025},
  pages     = {46 -- 55},
  year      = {2011},
  language  = {en}
}
@article{BehnamBeckerWeber2011,
  author    = {Behnam, S. and Becker, A. and Weber, Hans-Joachim},
  title     = {Clinical benefit and cost-efficiency of minimized perfusion circuits for extracorporeal circulation during cardiac surgery},
  series = {Zeitschrift f{\"u}r Herz-, Thorax- und Gef{\"a}ßchirurgie},
  volume    = {25},
  journal   = {Zeitschrift f{\"u}r Herz-, Thorax- und Gef{\"a}ßchirurgie},
  number    = {5},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0930-9225},
  pages     = {305 -- 306},
  year      = {2011},
  language  = {en}
}
@article{BerretzSkorupaSanderetal.2011,
  author    = {Berretz, Frank and Skorupa, Sasche and Sander, Volker and Belloum, Adam and Bubak, Marian},
  title     = {Actor-Driven Workflow Execution in Distributed Environments},
  series = {Euro-Par 2010 Parallel Processing Workshops : HeteroPAR, HPCC, HiBB, CoreGrid, UCHPC, HPCF, PROPER, CCPI, VHPC ; Ischia, Italy, August 31 - September 3, 2010 ; revised selected papers / Mario R. Guarracino ... (eds.)},
  journal   = {Euro-Par 2010 Parallel Processing Workshops : HeteroPAR, HPCC, HiBB, CoreGrid, UCHPC, HPCF, PROPER, CCPI, VHPC ; Ischia, Italy, August 31 - September 3, 2010 ; revised selected papers / Mario R. Guarracino ... (eds.)},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {978-3-642-21877-4},
  pages     = {287 -- 294},
  year      = {2011},
  language  = {en}
}
@article{Digel2011,
  author    = {Digel, Ilya},
  title     = {Primary thermosensory events in cells},
  series = {Transient receptor potential channels / Md. Shahidul Islam, ed.},
  journal   = {Transient receptor potential channels / Md. Shahidul Islam, ed.},
  publisher = {Springer},
  address   = {Dordrecht [u.a.]},
  isbn      = {978-94-007-0264-6},
  pages     = {451 -- 468},
  year      = {2011},
  language  = {en}
}
@article{DigelTemizArtmann2011,
  author    = {Digel, Ilya and Temiz Artmann, Ayseg{\"u}l},
  title     = {The emperor's new body : seeking for a blueprint of limb regeneration in humans},
  series = {Stem cell engineering : principles and applications / Gerhard M. Artmann ... eds.},
  journal   = {Stem cell engineering : principles and applications / Gerhard M. Artmann ... eds.},
  publisher = {Springer},
  address   = {Berlin [u.a.]},
  isbn      = {978-3-642-11864-7},
  pages     = {3 -- 37},
  year      = {2011},
  language  = {en}
}
@article{DashevskyLanzlKotliar2011,
  author    = {Dashevsky, Alexey V. and Lanzl, Ines M. and Kotliar, Konstantin},
  title     = {Non-penetrating intracanalicular partial trabeculectomy via the ostia of Schlemm's canal},
  series = {Graefe's Archive for Clinical and Experimental Ophthalmology},
  volume    = {249},
  journal   = {Graefe's Archive for Clinical and Experimental Ophthalmology},
  number    = {4},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0721-832x},
  pages     = {565 -- 573},
  year      = {2011},
  language  = {en}
}
@article{SeidovaKotliarFoergeretal.2009,
  author    = {Seidova, Seid-Fatima and Kotliar, Konstantin and Foerger, Frauke and Klopfer, Matthias and Lanzl, Ines},
  title     = {Functional retinal changes in Gaucher disease},
  series = {Documenta Ophthalmologica},
  volume    = {118},
  journal   = {Documenta Ophthalmologica},
  number    = {2},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {1573-2622},
  pages     = {151 -- 154},
  year      = {2009},
  language  = {en}
}
@article{PhamStaat2013,
  author    = {Pham, Phu Tinh and Staat, Manfred},
  title     = {An Upper Bound Algorithm for Limit and Shakedown Analysis of Bounded Linearly Kinematic Hardening Structures},
  series = {Limit State of Materials and Structures : Direct Methods 2. Saxc{\´e}, G{\´e}ry de (Hrsg.)},
  journal   = {Limit State of Materials and Structures : Direct Methods 2. Saxc{\´e}, G{\´e}ry de (Hrsg.)},
  publisher = {Springer},
  address   = {Dordrecht},
  isbn      = {978-94-007-5424-9},
  pages     = {71 -- 87},
  year      = {2013},
  language  = {en}
}
@article{TranStaat2013,
  author    = {Tran, Thanh Ngoc and Staat, Manfred},
  title     = {An Edge-Based Smoothed Finite Element Method for Primal-Dual Shakedown Analysis of Structures Under Uncertainties},
  series = {Limit State of Materials and Structures : Direct Methods 2. Saxc{\´e}, G{\´e}ry de (Hrsg.)},
  journal   = {Limit State of Materials and Structures : Direct Methods 2. Saxc{\´e}, G{\´e}ry de (Hrsg.)},
  publisher = {Springer},
  address   = {Dordrecht},
  isbn      = {978-94-007-5424-9},
  pages     = {89 -- 102},
  year      = {2013},
  language  = {en}
}
@article{NomdedeuWillenSchiefferetal.2012,
  author    = {Nomdedeu, Mar Monsonis and Willen, Christine and Schieffer, Andre and Arndt, Hartmut},
  title     = {Temperature-dependent ranges of coexistence in a model of a two-prey-one-predator microbial food web},
  series = {Marine Biology},
  volume    = {159},
  journal   = {Marine Biology},
  number    = {11},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1432-1793},
  doi       = {10.1007/s00227-012-1966-x},
  pages     = {2423 -- 2430},
  year      = {2012},
  abstract  = {The objective of our study was to analyze the effects of temperature on the population dynamics of a three-species food web consisting of two prey bacteria (Pedobacter sp. and Acinetobacter johnsonii) and a protozoan predator (Tetrahymena pyriformis) as model organisms. We assessed the effects of temperature on the growth rates of all three species with the objective of developing a model with four differential equations based on the experimental data. The following hypotheses were tested at a theoretical level: Firstly, temperature changes can affect the dynamic behavior of a system by temperature-dependent parameters and interactions and secondly, food web response to temperature cannot be derived from the single species temperature response. The main outcome of the study is that temperature changes affect the parameter range where coexistence is possible within all three species. This has significant consequences on our ideas regarding the evaluation of effects of global warming.},
  language  = {en}
}
@incollection{Weber1998,
  author    = {Weber, Hans-Joachim},
  title     = {Applied physics of compressible and incompressible fluids},
  series = {Critical care nephrology / [Hrsg.:] Claudio Ronco and Rinaldo Bellomo},
  booktitle = {Critical care nephrology / [Hrsg.:] Claudio Ronco and Rinaldo Bellomo},
  publisher = {Springer},
  address   = {Dordrecht},
  isbn      = {978-94-010-6306-7},
  pages     = {63 -- 84},
  year      = {1998},
  language  = {en}
}
@incollection{Dikta1998,
  author    = {Dikta, Gerhard},
  title     = {Fundamentals of applied probability and basic statistics},
  series = {Critical care nephrology / [Hrsg.:] Claudio Ronco and Rinaldo Bellomo},
  booktitle = {Critical care nephrology / [Hrsg.:] Claudio Ronco and Rinaldo Bellomo},
  publisher = {Springer},
  address   = {Dordrecht},
  isbn      = {978-94-010-6306-7},
  pages     = {51 -- 61},
  year      = {1998},
  language  = {en}
}
@article{DietzelWeberPorschenetal.1976,
  author    = {Dietzel, F. and Weber, Hans-Joachim and Porschen, W. and Feinendegen, L. E.},
  title     = {Zur W{\"a}rmeempfindlichkeit von oxischen und hypoxischen Zellen in einem Tumor},
  series = {Naturwissenschaften},
  volume    = {63},
  journal   = {Naturwissenschaften},
  number    = {12},
  publisher = {Springer},
  address   = {Heidelberg},
  issn      = {0028-1042},
  doi       = {10.1007/BF00622808},
  pages     = {585 -- 586},
  year      = {1976},
  language  = {de}
}
@incollection{TranStaat2014,
  author    = {Tran, Thanh Ngoc and Staat, Manfred},
  title     = {Shakedown analysis of Reissner-Mindlin plates using the edge-based smoothed finite element method},
  series = {Direct methods for limit states in structures and materials / Dieter Weichert ; Alan Ponter, ed.},
  booktitle = {Direct methods for limit states in structures and materials / Dieter Weichert ; Alan Ponter, ed.},
  publisher = {Springer},
  address   = {Dordrecht [u.a.]},
  isbn      = {978-94-007-6826-0 (Print) 978-94-007-6827-7 (Online)},
  doi       = {10.1007/978-94-007-6827-7_5},
  pages     = {101 -- 117},
  year      = {2014},
  abstract  = {This paper concerns the development of a primal-dual algorithm for limit and shakedown analysis of Reissner-Mindlin plates made of von Mises material. At each optimization iteration, the lower bound of the shakedown load multiplier is calculated simultaneously with the upper bound using the duality theory. An edge-based smoothed finite element method (ES-FEM) combined with the discrete shear gap (DSG) technique is used to improve the accuracy of the solutions and to avoid the transverse shear locking behaviour. The method not only possesses all inherent features of convergence and accuracy from ES-FEM, but also ensures that the total number of variables in the optimization problem is kept to a minimum compared with the standard finite element formulation. Numerical examples are presented to demonstrate the effectiveness of the present method.},
  language  = {en}
}
@article{KhaydukovaZadorozhnayaKirsanovetal.2014,
  author    = {Khaydukova, M. M. and Zadorozhnaya, O. A. and Kirsanov, D. O. and Iken, Heiko and Rolka, David and Sch{\"o}ning, Michael Josef and Babain, V. A. and Vlasov, Yu. G. and Legin, A. V.},
  title     = {Multivariate processing of atomic-force microscopy images for detection of the response of plasticized polymeric membranes},
  series = {Russian journal of applied chemistry},
  volume    = {87},
  journal   = {Russian journal of applied chemistry},
  number    = {3},
  publisher = {Springer},
  address   = {Dordrecht},
  issn      = {1608-3296 (E-Journal); 1070-4272 (Print)},
  doi       = {10.1134/S1070427214030112},
  pages     = {307 -- 314},
  year      = {2014},
  abstract  = {The possibility of using the atomic-force microscopy as a method for detection of the analytical signal from plasticized polymeric sensor membranes was analyzed. The surfaces of cadmium-selective membranes based on two polymeric matrices were examined. The digital images were processed with multivariate image analysis techniques. A correlation was found between the surface profile of an ion-selective membrane and the concentration of the ion in solution.},
  language  = {en}
}
@incollection{KnottSofroniaGerressenetal.2014,
  author    = {Knott, Thomas C. and Sofronia, Raluca E. and Gerressen, Marcus and Law, Yuen and Davidescu, Arjana and Savii, George G. and Gatzweiler, Karl-Heinz and Staat, Manfred and Kuhlen, Torsten W.},
  title     = {Preliminary bone sawing model for a virtual reality-based training simulator of bilateral sagittal split osteotomy},
  series = {Biomedical simulation : 6th International Symposium, ISBMS 2014, Strasbourg, France, October 16-17, 2014 : proceedings (Lecture notes in computer science : vol. 8789)},
  booktitle = {Biomedical simulation : 6th International Symposium, ISBMS 2014, Strasbourg, France, October 16-17, 2014 : proceedings (Lecture notes in computer science : vol. 8789)},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-12057-7 (Online)},
  doi       = {10.1007/978-3-319-12057-7_1},
  pages     = {1 -- 10},
  year      = {2014},
  abstract  = {Successful bone sawing requires a high level of skill and experience, which could be gained by the use of Virtual Reality-based simulators. A key aspect of these medical simulators is realistic force feedback. The aim of this paper is to model the bone sawing process in order to develop a valid training simulator for the bilateral sagittal split osteotomy, the most often applied corrective surgery in case of a malposition of the mandible. Bone samples from a human cadaveric mandible were tested using a designed experimental system. Image processing and statistical analysis were used for the selection of four models for the bone sawing process. The results revealed a polynomial dependency between the material removal rate and the applied force. Differences between the three segments of the osteotomy line and between the cortical and cancellous bone were highlighted.},
  language  = {en}
}
@incollection{FrotscherGossmannRaatschenetal.2015,
  author    = {Frotscher, Ralf and Goßmann, Matthias and Raatschen, Hans-J{\"u}rgen and Temiz Artmann, Ayseg{\"u}l and Staat, Manfred},
  title     = {Simulation of cardiac cell-seeded membranes using the edge-based smoothed FEM},
  series = {Shell and membrane theories in mechanics and biology. (Advanced structured materials ; 45)},
  booktitle = {Shell and membrane theories in mechanics and biology. (Advanced structured materials ; 45)},
  publisher = {Springer},
  address   = {Heidelberg},
  isbn      = {978-3-319-02534-6 ; 978-3-319-02535-3},
  pages     = {187 -- 212},
  year      = {2015},
  abstract  = {We present an electromechanically coupled Finite Element model for cardiac tissue. It bases on the mechanical model for cardiac tissue of Hunter et al. that we couple to the McAllister-Noble-Tsien electrophysiological model of purkinje fibre cells. The corresponding system of ordinary differential equations is implemented on the level of the constitutive equations in a geometrically and physically nonlinear version of the so-called edge-based smoothed FEM for plates. Mechanical material parameters are determined from our own pressure-deflection experimental setup. The main purpose of the model is to further examine the experimental results not only on mechanical but also on electrophysiological level down to ion channel gates. Moreover, we present first drug treatment simulations and validate the model with respect to the experiments.},
  language  = {en}
}
@incollection{TranStaat2015,
  author    = {Tran, Thanh Ngoc and Staat, Manfred},
  title     = {Uncertainty multimode failure and shakedown analysis of shells},
  series = {Direct methods for limit and shakedown analysis of structures / eds. Paolo Fuschi ...},
  booktitle = {Direct methods for limit and shakedown analysis of structures / eds. Paolo Fuschi ...},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-12927-3 (print) ; 978-3-319-12928-0 (online)},
  doi       = {10.1007/978-3-319-12928-0_14},
  pages     = {279 -- 298},
  year      = {2015},
  abstract  = {This paper presents a numerical procedure for reliability analysis of thin plates and shells with respect to plastic collapse or to inadaptation. The procedure involves a deterministic shakedown analysis for each probabilistic iteration, which is based on the upper bound approach and the use of the exact Ilyushin yield surface. Probabilistic shakedown analysis deals with uncertainties originated from the loads, material strength and thickness of the shell. Based on a direct definition of the limit state function, the calculation of the failure probability may be efficiently solved by using the First and Second Order Reliability Methods (FORM and SORM). The problem of reliability of structural systems (series systems) is handled by the application of a special technique which permits to find all the design points corresponding to all the failure modes. Studies show, in this case, that it improves considerably the FORM and SORM results.},
  language  = {en}
}
@article{HafnerDemetzWeickertetal.2014,
  author    = {Hafner, David and Demetz, Oliver and Weickert, Joachim and Reißel, Martin},
  title     = {Mathematical Foundations and Generalisations of the Census Transform for Robust Optic Flow Computation},
  series = {Journal of Mathematical Imaging and Vision},
  journal   = {Journal of Mathematical Imaging and Vision},
  publisher = {Springer},
  address   = {New York},
  issn      = {1573-7683 (Online)},
  doi       = {10.1007/s10851-014-0529-9},
  year      = {2014},
  language  = {en}
}
@article{DuongNguyenStaat2015,
  author    = {Duong, Minh Tuan and Nguyen, Nhu Huynh and Staat, Manfred},
  title     = {Physical response of hyperelastic models for composite materials and soft tissues},
  series = {Asia pacific journal on computational engineering},
  volume    = {2},
  journal   = {Asia pacific journal on computational engineering},
  number    = {3 (December 2015)},
  issn      = {2196-1166},
  doi       = {10.1186/s40540-015-0015-x},
  pages     = {1 -- 18},
  year      = {2015},
  language  = {en}
}
@article{FischerSelverGezeretal.2015,
  author    = {Fischer, Felix and Selver, M. Alper and Gezer, Sinem and Dicle, Oguz and Hillen, Walter},
  title     = {Systematic Parameterization, Storage, and Representation of Volumetric DICOM Data},
  series = {Journal of Medical and Biological Engineering},
  volume    = {35},
  journal   = {Journal of Medical and Biological Engineering},
  number    = {6},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {2199-4757},
  doi       = {10.1007/s40846-015-0097-5},
  pages     = {709 -- 723},
  year      = {2015},
  language  = {en}
}
@article{HacklMuellerStaatetal.2016,
  author    = {Hackl, Michael and M{\"u}ller, Lars-Peter and Staat, Manfred and Kahmann, Stephanie Lucina and Wegmann, Kilian},
  title     = {Proximal phalangeal neck fractures of the hand — a biomechanical comparison of three fixation techniques},
  series = {Knee surgery, sports traumatology, arthroscopy},
  volume    = {Volume 24},
  journal   = {Knee surgery, sports traumatology, arthroscopy},
  number    = {Supplement 1},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0942-2056},
  doi       = {10.1007/s00167-016-4080-7},
  pages     = {148 -- 149},
  year      = {2016},
  abstract  = {Plate osteosynthesis of displaced proximal phalangeal neck fractures of the hand allows early mobilization due to a stable internal fixation. Nevertheless, joint stiffness—because of soft tissue irritation—represents a common complication leading to high complication rates. Del Pinal et al. recently reported promising clinical results for a new, minimally invasive fixation technique with a cannulated headless intramedullary compression screw. Hence, the aim of this study was to compare plate fixation of proximal phalangeal neck fractures to less two less invasive techniques: Crossed k-wire fixation and intramedullary screw fixation. We hypothesized that these fixation techniques provide inferior stability when compared to plate osteosynthesis.},
  language  = {en}
}
@article{HacklKahmannWegmannetal.2016,
  author    = {Hackl, Michael and Kahmann, Stephanie Lucina and Wegmann, Kilian and Ries, Christian and Staat, Manfred and M{\"u}ller, Lars-Peter},
  title     = {Shortening osteotomy of the proximal radius — a treatment option for isolated osteoarthritis of the lateral column of the elbow joint?},
  series = {Knee surgery, sports traumatology, arthroscopy},
  volume    = {Volume 24},
  journal   = {Knee surgery, sports traumatology, arthroscopy},
  number    = {Supplement 1},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0942-2056},
  doi       = {10.1007/s00167-016-4080-7},
  pages     = {128 -- 129},
  year      = {2016},
  abstract  = {Treatment of posttraumatic osteoarthritis of the radial column of the elbow joint remains a challenging yet common issue. While partial joint replacement leads to high revision rates, radial head excision has shown to severely increase joint instability. Shortening osteotomy of the radius could be an option to decrease the contact pressure of the radiohumeral joint and thereby pain levels without causing valgus instability. Hence, the aim of this biomechanical study was to evaluate the effects of radial shortening on axial load distribution and valgus stability of the elbow joint.},
  language  = {en}
}
@article{HacklLeschingerStaatetal.2016,
  author    = {Hackl, Michael and Leschinger, T. and Staat, Manfred and M{\"u}ller, Lars-Peter and Wegmann, Kilian},
  title     = {Reconstruction of the interosseous membrane in the Essex Lopresti lesion — a biomechanical evaluation},
  series = {Knee surgery, sports traumatology, arthroscopy},
  volume    = {Volume 24},
  journal   = {Knee surgery, sports traumatology, arthroscopy},
  number    = {Supplement 1},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0942-2056},
  doi       = {10.1007/s00167-016-4080-7},
  pages     = {130 -- 131},
  year      = {2016},
  abstract  = {Surgical reconstruction of the interosseous membrane (IOM) could restore longitudinal forearm stability to avoid persisting disability due to capituloradial and ulnocarpal impingement in Essex Lopresti lesions. This biomechanical study aimed to assess longitudinal forearm stability of intact specimens, after sectioning of the IOM and after reconstruction with a TightRope construct using either a single or double bundle technique.},
  language  = {en}
}
@article{WegmannHacklStaatetal.2016,
  author    = {Wegmann, Kilian and Hackl, Michael and Staat, Manfred and Mayer, Katharina and M{\"u}ller, Lars-Peter},
  title     = {Double plate osteosynthesis of proximal ulna fractures: biomechanical and clinical results},
  series = {Knee surgery, sports traumatology, arthroscopy},
  volume    = {Volume 24},
  journal   = {Knee surgery, sports traumatology, arthroscopy},
  number    = {Supplement 1},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0942-2056},
  doi       = {10.1007/s00167-016-4079-0},
  pages     = {58 -- 59},
  year      = {2016},
  abstract  = {While plate fixation of proximal ulna fractures might lead to superior clinical results compared to tension band wiring, regular plates represent an established risk factor for wound complications. The olecranon double plates (Medartis, Basel, CH) might decrease complications related to the osteosynthesis because of their low profile and better anatomical fit. This study aimed to evaluate the biomechanical performance and clinical results of the olecranon double plates.},
  language  = {en}
}
@article{KotliarLanzl2016,
  author    = {Kotliar, Konstantin and Lanzl, I. M.},
  title     = {Mit Statistik gemeistert: perfekte Augentropfen und idealer Screeningtest : M{\"o}glichkeiten und Grenzen statistischer Methoden beim Glaukom},
  series = {Der Ophthalmologe: Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft},
  journal   = {Der Ophthalmologe: Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft},
  number    = {113},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0941-293X},
  doi       = {10.1007/s00347-016-0312-y},
  pages     = {838 -- 843},
  year      = {2016},
  abstract  = {Hintergrund Die Anwendung und das Verst{\"a}ndnis von Statistik sind sehr wichtig f{\"u}r die biomedizinische Forschung und f{\"u}r die klinische Praxis. Dies gilt insbesondere auch zur Absch{\"a}tzung der M{\"o}glichkeiten unterschiedlichster Diagnostik- und Therapieoptionen beim Glaukom. Die scheinbare Komplexit{\"a}t der Statistik, die zum Teil dem „gesunden Menschenverstand" zu widersprechen scheint, zusammen mit der nur vorsichtigen Akzeptanz der Statistik bei vielen Medizinern k{\"o}nnen zu bewussten und unbewussten Manipulationen bei der Datendarstellung und -interpretation f{\"u}hren. Ziel der Arbeit Ziel ist die verst{\"a}ndliche Darstellung einiger typischer Fehler in der medizinisch-statistischen Datenbehandlung. Material und Methoden Anhand hypothetischer Beispiele aus der Glaukomdiagnostik erfolgen die Darstellung der Wirkung eines hypotensiven Medikamentes sowie die Beurteilung der Ergebnisse eines diagnostischen Tests. Es werden die typischsten statistischen Einsatzbereiche und Irrtumsquellen ausf{\"u}hrlich und verst{\"a}ndlich analysiert Ergebnisse Mechanismen von Datenmanipulation und falscher Dateninterpretation werden aufgekl{\"a}rt. Typische Irrtumsquellen bei der statistischen Auswertung und Datendarstellung werden dabei erl{\"a}utert. Schlussfolgerungen Die erl{\"a}uterten praktischen Beispiele zeigen die Notwendigkeit, die Grundlagen der Statistik zu verstehen und korrekt anwenden zu k{\"o}nnen. Fehlendes Grundlagenwissen und Halbwissen der medizinischen Statistik k{\"o}nnen zu folgenschweren Missverst{\"a}ndnissen und falschen Entscheidungen in der medizinischen Forschung, aber auch in der klinischen Praxis f{\"u}hren.},
  language  = {de}
}
@article{KnobeGiesenPlateetal.2016,
  author    = {Knobe, M. and Giesen, M. and Plate, S. and Gradl-Dietsch, G. and Buecking, B. and Eschbach, D. and Laack, Walter van and Pape, H.-C.},
  title     = {The Aachen mobility and balance index to measure physiological falls risk: a comparison with the Tinetti POMA scale},
  series = {European Journal Of Trauma And Emergency Surgery},
  volume    = {42},
  journal   = {European Journal Of Trauma And Emergency Surgery},
  number    = {5},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1863-9941},
  doi       = {10.1007/s00068-016-0693-2},
  pages     = {537 -- 545},
  year      = {2016},
  abstract  = {Purpose The most commonly used mobility assessments for screening risk of falls among older adults are rating scales such as the Tinetti performance oriented mobility assessment (POMA). However, its correlation with falls is not always predictable and disadvantages of the scale include difficulty to assess many of the items on a 3-point scale and poor specificity. The purpose of this study was to describe the ability of the new Aachen Mobility and Balance Index (AMBI) to discriminate between subjects with a fall history and subjects without such events in comparison to the Tinetti POMA Scale. Methods For this prospective cohort study, 24 participants in the study group and 10 in the control group were selected from a population of patients in our hospital who had met the stringent inclusion criteria. Both groups completed the Tinetti POMA Scale (gait and balance component) and the AMBI (tandem stance, tandem walk, ten-meter-walk-test, sit-to-stand with five repetitions, 360° turns, timed-up-and-go-test and measurement of the dominant hand grip strength). A history of falls and hospitalization in the past year were evaluated retrospectively. The relationships among the mobility tests were examined with Bland-Altmananalysis. Receiver-operated characteristics curves, sensitivity and specificity were calculated. Results The study showed a strong negative correlation between the AMBI (17 points max., highest fall risk) and Tinetti POMA Scale (28 points max., lowest fall risk; r = -0.78, p < 0.001) with an excellent discrimination between community-dwelling older people and a younger control group. However, there were no differences in any of the mobility and balance measurements between participants with and without a fall history with equal characteristics in test comparison (AMBI vs. Tinetti POMA Scale: AUC 0.570 vs. 0.598; p = 0.762). The Tinetti POMA Scale (cut-off <20 points) showed a sensitivity of 0.45 and a specificity of 0.69, the AMBI a sensitivity of 0.64 and a specificity of 0.46 (cut-off >5 points). Conclusion The AMBI comprises mobility and balance tasks with increasing difficulty as well as a measurement of the dominant hand-grip strength. Its ability to identify fallers was comparable to the Tinetti POMA Scale. However, both measurement sets showed shortcomings in discrimination between fallers and non-fallers based on a self-reported retrospective falls-status.},
  language  = {en}
}
@article{BelavyAlbrachtBruggemannetal.2016,
  author    = {Belavy, Daniel L. and Albracht, Kirsten and Bruggemann, Gert-Peter and Vergroesen, Pieter-Paul A. and Dieen, Jaap H. van},
  title     = {Can exercise positively influence the intervertebral disc?},
  series = {Sports Medicine},
  volume    = {46},
  journal   = {Sports Medicine},
  number    = {4},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1179-2035},
  doi       = {10.1007/s40279-015-0444-2},
  pages     = {473 -- 485},
  year      = {2016},
  abstract  = {To better understand what kinds of sports and exercise could be beneficial for the intervertebral disc (IVD), we performed a review to synthesise the literature on IVD adaptation with loading and exercise. The state of the literature did not permit a systematic review; therefore, we performed a narrative review. The majority of the available data come from cell or whole-disc loading models and animal exercise models. However, some studies have examined the impact of specific sports on IVD degeneration in humans and acute exercise on disc size. Based on the data available in the literature, loading types that are likely beneficial to the IVD are dynamic, axial, at slow to moderate movement speeds, and of a magnitude experienced in walking and jogging. Static loading, torsional loading, flexion with compression, rapid loading, high-impact loading and explosive tasks are likely detrimental for the IVD. Reduced physical activity and disuse appear to be detrimental for the IVD. We also consider the impact of genetics and the likelihood of a 'critical period' for the effect of exercise in IVD development. The current review summarises the literature to increase awareness amongst exercise, rehabilitation and ergonomic professionals regarding IVD health and provides recommendations on future directions in research.},
  language  = {en}
}
@article{AlbrachtArampatzis2013,
  author    = {Albracht, Kirsten and Arampatzis, Adamantios},
  title     = {Exercise-induced changes in triceps surae tendon stiffness and muscle strength affect running economy in humans},
  series = {European Journal of Applied Physiology},
  volume    = {113},
  journal   = {European Journal of Applied Physiology},
  number    = {6},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1439-6327},
  doi       = {10.1007/s00421-012-2585-4},
  pages     = {1605 -- 1615},
  year      = {2013},
  language  = {en}
}
@article{KatzPoghossianSchoening2017,
  author    = {Katz, Evgeny and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Enzyme-based logic gates and circuits - analytical applications and interfacing with electronics},
  series = {Analytical and Bioanalytical Chemistry},
  volume    = {409},
  journal   = {Analytical and Bioanalytical Chemistry},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1618-2650},
  doi       = {10.1007/s00216-016-0079-7},
  pages     = {81 -- 94},
  year      = {2017},
  abstract  = {The paper is an overview of enzyme-based logic gates and their short circuits, with specific examples of Boolean AND and OR gates, and concatenated logic gates composed of multi-step enzyme-biocatalyzed reactions. Noise formation in the biocatalytic reactions and its decrease by adding a "filter" system, converting convex to sigmoid response function, are discussed. Despite the fact that the enzyme-based logic gates are primarily considered as components of future biomolecular computing systems, their biosensing applications are promising for immediate practical use. Analytical use of the enzyme logic systems in biomedical and forensic applications is discussed and exemplified with the logic analysis of biomarkers of various injuries, e.g., liver injury, and with analysis of biomarkers characteristic of different ethnicity found in blood samples on a crime scene. Interfacing of enzyme logic systems with modified electrodes and semiconductor devices is discussed, giving particular attention to the interfaces functionalized with signal-responsive materials. Future perspectives in the design of the biomolecular logic systems and their applications are discussed in the conclusion.},
  language  = {en}
}
@article{HacklWegmannKahmannetal.2017,
  author    = {Hackl, Michael and Wegmann, Kilian and Kahmann, Stephanie Lucina and Heinze, Nicolai and Staat, Manfred and Neiss, Wolfram F. and Scaal, Martin and M{\"u}ller, Lars P.},
  title     = {Radial shortening osteotomy reduces radiocapitellar contact pressures while preserving valgus stability of the elbow},
  series = {Knee Surgery, Sports Traumatology, Arthroscopy},
  volume    = {25},
  journal   = {Knee Surgery, Sports Traumatology, Arthroscopy},
  number    = {7},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1433-7347},
  doi       = {10.1007/s00167-017-4468-z},
  pages     = {2280 -- 2288},
  year      = {2017},
  language  = {en}
}
@article{MoraisGomesSilvaetal.2017,
  author    = {Morais, Paulo V. and Gomes, Vanderley F., Jr. and Silva, Anielle C. A. and Dantas, Noelio O. and Sch{\"o}ning, Michael Josef and Siqueira, Jos{\´e} R., Jr.},
  title     = {Nanofilm of ZnO nanocrystals/carbon nanotubes as biocompatible layer for enzymatic biosensors in capacitive field-effect devices},
  series = {Journal of Materials Science},
  volume    = {52},
  journal   = {Journal of Materials Science},
  number    = {20},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1573-4803},
  doi       = {10.1007/s10853-017-1369-y},
  pages     = {12314 -- 12325},
  year      = {2017},
  abstract  = {The incorporation of nanomaterials that are biocompatible with different types of biological compounds has allowed the development of a new generation of biosensors applied especially in the biomedical field. In particular, the integration of film-based nanomaterials employed in field-effect devices can be interesting to develop biosensors with enhanced properties. In this paper, we studied the fabrication of sensitive nanofilms combining ZnO nanocrystals and carbon nanotubes (CNTs), prepared by means of the layer-by-layer (LbL) technique, in a capacitive electrolyte-insulator-semiconductor (EIS) structure for detecting glucose and urea. The ZnO nanocrystals were incorporated in a polymeric matrix of poly(allylamine) hydrochloride (PAH), and arranged with multi-walled CNTs in a LbL PAH-ZnO/CNTs film architecture onto EIS chips. The electrochemical characterizations were performed by capacitance-voltage and constant capacitance measurements, while the morphology of the films was characterized by atomic force microscopy. The enzymes glucose oxidase and urease were immobilized on film's surface for detection of glucose and urea, respectively. In order to obtain glucose and urea biosensors with optimized amount of sensitive films, we investigated the ideal number of bilayers for each detection system. The glucose biosensor showed better sensitivity and output signal for an LbL PAH-ZnO/CNTs nanofilm with 10 bilayers. On the other hand, the urea biosensor presented enhanced properties even for the first bilayer, exhibiting high sensitivity and output signal. The presence of the LbL PAH-ZnO/CNTs films led to biosensors with better sensitivity and enhanced response signal, demonstrating that the adequate use of nanostructured films is feasible for proof-of-concept biosensors with improved properties that may be employed for biomedical applications.},
  language  = {en}
}
@incollection{PoghossianSchoening2017,
  author    = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Nanomaterial-Modified Capacitive Field-Effect Biosensors},
  series = {Springer Series on Chemical Sensors and Biosensors (Methods and Applications)},
  booktitle = {Springer Series on Chemical Sensors and Biosensors (Methods and Applications)},
  publisher = {Springer},
  address   = {Berlin, Heidelberg},
  doi       = {10.1007/5346_2017_2},
  pages     = {1 -- 25},
  year      = {2017},
  abstract  = {The coupling of charged molecules, nanoparticles, and more generally, inorganic/organic nanohybrids with semiconductor field-effect devices based on an electrolyte-insulator-semiconductor (EIS) system represents a very promising strategy for the active tuning of electrochemical properties of these devices and, thus, opening new opportunities for label-free biosensing by the intrinsic charge of molecules. The simplest field-effect sensor is a capacitive EIS sensor, which represents a (bio-)chemically sensitive capacitor. In this chapter, selected examples of recent developments in the field of label-free biosensing using nanomaterial-modified capacitive EIS sensors are summarized. In the first part, we present applications of EIS sensors modified with negatively charged gold nanoparticles for the label-free electrostatic detection of positively charged small proteins and macromolecules, for monitoring the layer-by-layer formation of oppositely charged polyelectrolyte (PE) multilayers as well as for the development of an enzyme-based biomolecular logic gate. In the second part, examples of a label-free detection by means of EIS sensors modified with a positively charged weak PE layer are demonstrated. These include electrical detection of on-chip and in-solution hybridized DNA (deoxyribonucleic acid) as well as an EIS sensor with pH-responsive weak PE/enzyme multilayers for enhanced field-effect biosensing.},
  language  = {en}
}
@incollection{TranTranMatthiesetal.2017,
  author    = {Tran, N. T. and Tran, Thanh Ngoc and Matthies, M. G. and Stavroulakis, G. E. and Staat, Manfred},
  title     = {Shakedown Analysis Under Stochastic Uncertainty by Chance Constrained Programming},
  series = {Advances in Direct Methods for Materials and Structures},
  booktitle = {Advances in Direct Methods for Materials and Structures},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-59810-9},
  doi       = {10.1007/978-3-319-59810-9_6},
  pages     = {85 -- 103},
  year      = {2017},
  abstract  = {In this paper we propose a stochastic programming method to analyse limit and shakedown of structures under uncertainty condition of strength. Based on the duality theory, the shakedown load multiplier formulated by the kinematic theorem is proved actually to be the dual form of the shakedown load multiplier formulated by static theorem. In this investigation a dual chance constrained programming algorithm is developed to calculate simultaneously both the upper and lower bounds of the plastic collapse limit and the shakedown limit. The edge-based smoothed finite element method (ES-FEM) with three-node linear triangular elements is used for structural analysis.},
  language  = {en}
}
@article{RoehlenPilasSchoeningetal.2017,
  author    = {R{\"o}hlen, Desiree and Pilas, Johanna and Sch{\"o}ning, Michael Josef and Selmer, Thorsten},
  title     = {Development of an amperometric biosensor platform for the combined determination of l-Malic, Fumaric, and l-Aspartic acid},
  series = {Applied Biochemistry and Biotechnology},
  volume    = {183},
  journal   = {Applied Biochemistry and Biotechnology},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1559-0291},
  doi       = {10.1007/s12010-017-2578-1},
  pages     = {566 -- 581},
  year      = {2017},
  abstract  = {Three amperometric biosensors have been developed for the detection of L-malic acid, fumaric acid, and L -aspartic acid, all based on the combination of a malate-specific dehydrogenase (MDH, EC 1.1.1.37) and diaphorase (DIA, EC 1.8.1.4). The stepwise expansion of the malate platform with the enzymes fumarate hydratase (FH, EC 4.2.1.2) and aspartate ammonia-lyase (ASPA, EC 4.3.1.1) resulted in multi-enzyme reaction cascades and, thus, augmentation of the substrate spectrum of the sensors. Electrochemical measurements were carried out in presence of the cofactor β-nicotinamide adenine dinucleotide (NAD+) and the redox mediator hexacyanoferrate (III) (HCFIII). The amperometric detection is mediated by oxidation of hexacyanoferrate (II) (HCFII) at an applied potential of + 0.3 V vs. Ag/AgCl. For each biosensor, optimum working conditions were defined by adjustment of cofactor concentrations, buffer pH, and immobilization procedure. Under these improved conditions, amperometric responses were linear up to 3.0 mM for L-malate and fumarate, respectively, with a corresponding sensitivity of 0.7 μA mM-1 (L-malate biosensor) and 0.4 μA mM-1 (fumarate biosensor). The L-aspartate detection system displayed a linear range of 1.0-10.0 mM with a sensitivity of 0.09 μA mM-1. The sensor characteristics suggest that the developed platform provides a promising method for the detection and differentiation of the three substrates.},
  language  = {en}
}
@article{GaribaldiBegingCaneseetal.2017,
  author    = {Garibaldi, F. and Beging, Stefan and Canese, R. and Carpinelli, G. and Clinthorne, N. and Colilli, S. and Cosentino, L. and Finocchiaro, P. and Giuliani, F. and Gricia, M. and Lucentini, M. and Majewski, S. and Monno, E. and Musico, P. and Santavenere, F. and T{\"o}dter, J. and Wegener, Hans-Peter and Ziemons, Karl},
  title     = {A novel TOF-PET MRI detector for diagnosis and follow up of the prostate cancer},
  series = {European Physical Journal Plus},
  volume    = {132},
  journal   = {European Physical Journal Plus},
  number    = {9},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {2190-5444},
  doi       = {10.1140/epjp/i2017-11662-x},
  year      = {2017},
  language  = {en}
}
@incollection{BhattaraiFrotscherStaat2018,
  author    = {Bhattarai, Aroj and Frotscher, Ralf and Staat, Manfred},
  title     = {Computational Analysis of Pelvic Floor Dysfunction},
  series = {Women's Health and Biomechanics},
  booktitle = {Women's Health and Biomechanics},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-71574-2},
  doi       = {10.1007/978-3-319-71574-2_17},
  pages     = {217 -- 230},
  year      = {2018},
  abstract  = {Pelvic floor dysfunction (PFD) is characterized by the failure of the levator ani (LA) muscle to maintain the pelvic hiatus, resulting in the descent of the pelvic organs below the pubococcygeal line. This chapter adopts the modified Humphrey material model to consider the effect of the muscle fiber on passive stretching of the LA muscle. The deformation of the LA muscle subjected to intra-abdominal pressure during Valsalva maneuver is compared with the magnetic resonance imaging (MRI) examination of a nulliparous female. Numerical result shows that the fiber-based Humphrey model simulates the muscle behavior better than isotropic constitutive models. Greater posterior movement of the LA muscle widens the levator hiatus due to lack of support from the anococcygeal ligament and the perineal structure as a consequence of birth-related injury and aging. Old and multiparous females with uncontrolled urogenital and rectal hiatus tend to develop PFDs such as prolapse and incontinence.},
  language  = {en}
}
@incollection{BhattaraiStaat2018,
  author    = {Bhattarai, Aroj and Staat, Manfred},
  title     = {Mechanics of soft tissue reactions to textile mesh implants},
  series = {Biological, Physical and Technical Basics of Cell Engineering},
  booktitle = {Biological, Physical and Technical Basics of Cell Engineering},
  editor    = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya},
  publisher = {Springer},
  address   = {Singapore},
  isbn      = {978-981-10-7904-7},
  doi       = {10.1007/978-981-10-7904-7_11},
  pages     = {251 -- 275},
  year      = {2018},
  abstract  = {For pelvic floor disorders that cannot be treated with non-surgical procedures, minimally invasive surgery has become a more frequent and safer repair procedure. More than 20 million prosthetic meshes are implanted each year worldwide. The simple selection of a single synthetic mesh construction for any level and type of pelvic floor dysfunctions without adopting the design to specific requirements increase the risks for mesh related complications. Adverse events are closely related to chronic foreign body reaction, with enhanced formation of scar tissue around the surgical meshes, manifested as pain, mesh erosion in adjacent structures (with organ tissue cut), mesh shrinkage, mesh rejection and eventually recurrence. Such events, especially scar formation depend on effective porosity of the mesh, which decreases discontinuously at a critical stretch when pore areas decrease making the surgical reconstruction ineffective that further augments the re-operation costs. The extent of fibrotic reaction is increased with higher amount of foreign body material, larger surface, small pore size or with inadequate textile elasticity. Standardized studies of different meshes are essential to evaluate influencing factors for the failure and success of the reconstruction. Measurements of elasticity and tensile strength have to consider the mesh anisotropy as result of the textile structure. An appropriate mesh then should show some integration with limited scar reaction and preserved pores that are filled with local fat tissue. This chapter reviews various tissue reactions to different monofilament mesh implants that are used for incontinence and hernia repairs and study their mechanical behavior. This helps to predict the functional and biological outcomes after tissue reinforcement with meshes and permits further optimization of the meshes for the specific indications to improve the success of the surgical treatment.},
  language  = {en}
}
@incollection{DuongSeifarthTemizArtmannetal.2018,
  author    = {Duong, Minh Tuan and Seifarth, Volker and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard and Staat, Manfred},
  title     = {Growth Modelling Promoting Mechanical Stimulation of Smooth Muscle Cells of Porcine Tubular Organs in a Fibrin-PVDF Scaffold},
  series = {Biological, Physical and Technical Basics of Cell Engineering},
  booktitle = {Biological, Physical and Technical Basics of Cell Engineering},
  editor    = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya},
  publisher = {Springer},
  address   = {Singapore},
  isbn      = {978-981-10-7904-7},
  doi       = {10.1007/978-981-10-7904-7_9},
  pages     = {209 -- 232},
  year      = {2018},
  abstract  = {Reconstructive surgery and tissue replacements like ureters or bladders reconstruction have been recently studied, taking into account growth and remodelling of cells since living cells are capable of growing, adapting, remodelling or degrading and restoring in order to deform and respond to stimuli. Hence, shapes of ureters or bladders and their microstructure change during growth and these changes strongly depend on external stimuli such as training. We present the mechanical stimulation of smooth muscle cells in a tubular fibrin-PVDFA scaffold and the modelling of the growth of tissue by stimuli. To this end, mechanotransduction was performed with a kyphoplasty balloon catheter that was guided through the lumen of the tubular structure. The bursting pressure was examined to compare the stability of the incubated tissue constructs. The results showed the significant changes on tissues with training by increasing the burst pressure as a characteristic mechanical property and the smooth muscle cells were more oriented with uniformly higher density. Besides, the computational growth models also exhibited the accurate tendencies of growth of the cells under different external stimuli. Such models may lead to design standards for the better layered tissue structure in reconstructing of tubular organs characterized as composite materials such as intestines, ureters and arteries.},
  language  = {en}
}
@incollection{FrotscherStaat2018,
  author    = {Frotscher, Ralf and Staat, Manfred},
  title     = {Towards Patient-Specific Computational Modeling of hiPS-Derived Cardiomyocyte Function and Drug Action},
  series = {Biological, Physical and Technical Basics of Cell Engineering},
  booktitle = {Biological, Physical and Technical Basics of Cell Engineering},
  editor    = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya},
  publisher = {Springer},
  address   = {Singapore},
  isbn      = {978-981-10-7904-7},
  doi       = {10.1007/978-981-10-7904-7_10},
  pages     = {233 -- 250},
  year      = {2018},
  abstract  = {Human-induced pluripotent stem cell-derived cardiomyocytes (hiPS-CM) today are widely used for the investigation of normal electromechanical cardiac function, of cardiac medication and of mutations. Computational models are thus established that simulate the behavior of this kind of cells. This section first motivates the modeling of hiPS-CM and then presents and discusses several modeling approaches of microscopic and macroscopic constituents of human-induced pluripotent stem cell-derived and mature human cardiac tissue. The focus is led on the mapping of the computational results one can achieve with these models onto mature human cardiomyocyte models, the latter being the real matter of interest. Model adaptivity is the key feature that is discussed because it opens the way for modeling various biological effects like biological variability, medication, mutation and phenotypical expression. We compare the computational with experimental results with respect to normal cardiac function and with respect to inotropic and chronotropic drug effects. The section closes with a discussion on the status quo of the specificity of computational models and on what challenges have to be solved to reach patient-specificity.},
  language  = {en}
}
@incollection{DigelAkimbekovKistaubayevaetal.2018,
  author    = {Digel, Ilya and Akimbekov, Nuraly Sh. and Kistaubayeva, Aida and Zhubanova, Azhar A.},
  title     = {Microbial Sampling from Dry Surfaces: Current Challenges and Solutions},
  series = {Biological, Physical and Technical Basics of Cell Engineering},
  booktitle = {Biological, Physical and Technical Basics of Cell Engineering},
  editor    = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya},
  publisher = {Springer},
  address   = {Singapore},
  isbn      = {978-981-10-7904-7},
  doi       = {10.1007/978-981-10-7904-7_19},
  pages     = {421 -- 456},
  year      = {2018},
  abstract  = {Sampling of dry surfaces for microorganisms is a main component of microbiological safety and is of critical importance in many fields including epidemiology, astrobiology as well as numerous branches of medical and food manufacturing. Aspects of biofilm formation, analysis and removal in aqueous solutions have been thoroughly discussed in literature. In contrast, microbial communities on air-exposed (dry) surfaces have received significantly less attention. Diverse surface sampling methods have been developed in order to address various surfaces and microbial groups, but they notoriously show poor repeatability, low recovery rates and suffer from lack of mutual consistency. Quantitative sampling for viable microorganisms represents a particular challenge, especially on porous and irregular surfaces. Therefore, it is essential to examine in depth the factors involved in microorganisms' recovery efficiency and accuracy depending on the sampling technique used. Microbial colonization, retention and community composition on different dry surfaces are very complex and rely on numerous physicochemical and biological factors. This study is devoted to analyze and review the (a) physical phenomena and intermolecular forces relevant for microbiological surface sampling; (b) challenges and problems faced by existing sampling methods for viable microorganisms and (c) current directions of engineering and research aimed at improvement of quality and efficiency of microbiological surface sampling.},
  language  = {en}
}
@article{Dikta2017,
  author    = {Dikta, Gerhard},
  title     = {Semi-parametric random censorship models},
  series = {From Statistics to Mathematical Finance : Festschrift in Honour of Winfried Stute},
  journal   = {From Statistics to Mathematical Finance : Festschrift in Honour of Winfried Stute},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {978-3-319-50986-0},
  doi       = {10.1007/978-3-319-50986-0_3},
  pages     = {43 -- 56},
  year      = {2017},
  language  = {en}
}
@incollection{YoshinobuKrauseMiyamotoetal.2018,
  author    = {Yoshinobu, Tatsuo and Krause, Steffi and Miyamoto, Ko-ichiro and Werner, Frederik and Poghossian, Arshak and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {(Bio-)chemical Sensing and Imaging by LAPS and SPIM},
  series = {Label-free biosensing: advanced materials, devices and applications},
  booktitle = {Label-free biosensing: advanced materials, devices and applications},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-75219-8},
  pages     = {103 -- 132},
  year      = {2018},
  abstract  = {The light-addressable potentiometric sensor (LAPS) and scanning photo-induced impedance microscopy (SPIM) are two closely related methods to visualise the distributions of chemical species and impedance, respectively, at the interface between the sensing surface and the sample solution. They both have the same field-effect structure based on a semiconductor, which allows spatially resolved and label-free measurement of chemical species and impedance in the form of a photocurrent signal generated by a scanning light beam. In this article, the principles and various operation modes of LAPS and SPIM, functionalisation of the sensing surface for measuring various species, LAPS-based chemical imaging and high-resolution sensors based on silicon-on-sapphire substrates are described and discussed, focusing on their technical details and prospective applications.},
  language  = {en}
}