@article{WeiheAnsgarRoethetal.2013,
  author    = {Weihe, Stefan and Ansgar, Ernst and R{\"o}th, Thilo and Proksch, Johannes},
  title     = {Leichtmetall-Stahl-Verbundguss im Nutzfahrzeugbau},
  series = {Lightweight Design},
  volume    = {6},
  journal   = {Lightweight Design},
  number    = {2},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {2192-8738 (Online)},
  pages     = {38 -- 43},
  year      = {2013},
  abstract  = {In modernen Fahrzeugkarosserien der Großserie kommen zunehmend Materialmischbauweisen zur Anwendung. In Zusammenarbeit der Daimler AG, der Tower Automotive Holding GmbH, der Imperia GmbH sowie der Partnerunternehmen KSM Castings GmbH und Schaufler Tooling GmbH \& Co. KG wird das Leichtbaupotenzial von Stahlblech-AluminiumverbundgussHybriden am Beispiel des vorderen Dachquertr{\"a}gers des Mercedes-Benz Viano/Vito ausf{\"u}hrlich untersucht.},
  language  = {de}
}
@inproceedings{SchuhGottschalkHoehneetal.2008,
  author    = {Schuh, G{\"u}nther and Gottschalk, Sebastian and H{\"o}hne, Tim and Attig, Philipp},
  title     = {Further Potentials of Smart Logistics},
  series = {Manufacturing Systems and Technologies for the New Frontier},
  booktitle = {Manufacturing Systems and Technologies for the New Frontier},
  editor    = {Mitsuishi, M.},
  publisher = {Springer},
  address   = {London},
  isbn      = {978-1-84800-267-8},
  doi       = {10.1007/978-1-84800-267-8_18},
  pages     = {93 -- 96},
  year      = {2008},
  language  = {en}
}
@incollection{TippkoetterMoehringRothetal.2019,
  author    = {Tippk{\"o}tter, Nils and M{\"o}hring, Sophie and Roth, Jasmine and Wulfhorst, Helene},
  title     = {Logistics of lignocellulosic feedstocks: preprocessing as a preferable option},
  series = {Biorefineries},
  booktitle = {Biorefineries},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-97117-9},
  doi       = {10.1007/10_2017_58},
  pages     = {43 -- 68},
  year      = {2019},
  abstract  = {In comparison to crude oil, biorefinery raw materials are challenging in concerns of transport and storage. The plant raw materials are more voluminous, so that shredding and compacting usually are necessary before transport. These mechanical processes can have a negative influence on the subsequent biotechnological processing and shelf life of the raw materials. Various approaches and their effects on renewable raw materials are shown. In addition, aspects of decentralized pretreatment steps are discussed. Another important aspect of pretreatment is the varying composition of the raw materials depending on the growth conditions. This problem can be solved with advanced on-site spectrometric analysis of the material.},
  language  = {en}
}
@incollection{DuweTippkoetterUlber2018,
  author    = {Duwe, A. and Tippk{\"o}tter, Nils and Ulber, R.},
  title     = {Lignocellulose-Biorefinery: Ethanol-Focused},
  series = {Biorefineries},
  booktitle = {Biorefineries},
  publisher = {Springer},
  address   = {Cham},
  doi       = {10.1007/10_2016_72},
  pages     = {177 -- 215},
  year      = {2018},
  abstract  = {The development prospects of the world markets for petroleum and other liquid fuels are diverse and partly contradictory. However, comprehensive changes for the energy supply of the future are essential. Notwithstanding the fact that there are still very large deposits of energy resources from a geological point of view, the finite nature of conventional oil reserves is indisputable. To reduce our dependence on oil, the EU, the USA, and other major economic zones rely on energy diversification. For this purpose, alternative materials and technologies are being sought, and is most obvious in the transport sector. The objective is to progressively replace fossil fuels with renewable and more sustainable fuels. In this respect, biofuels have a pre-eminent position in terms of their capability of blending with fossil fuels and being usable in existing cars without substantial modification. Ethanol can be considered as the primary renewable liquid fuel. In this chapter enzymes, micro-organisms, and processes for ethanol production based on renewable resources are described.},
  language  = {en}
}
@article{BeckerDelfmannDietrichetal.2016,
  author    = {Becker, J{\"o}rg and Delfmann, Patrick and Dietrich, Hanns-Alexander and Steinhorst, Matthias and Eggert, Mathias},
  title     = {Business Process Compliance Checking — Applying and Evaluating a Generic Pattern Matching Approach for Conceptual Models in the Financial Sector},
  series = {Information Systems Frontiers},
  volume    = {18},
  journal   = {Information Systems Frontiers},
  number    = {2},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1572-9419},
  doi       = {10.1007/s10796-014-9529-y},
  pages     = {359 -- 405},
  year      = {2016},
  abstract  = {Given the strong increase in regulatory requirements for business processes the management of business process compliance becomes a more and more regarded field in IS research. Several methods have been developed to support compliance checking of conceptual models. However, their focus on distinct modeling languages and mostly linear (i.e., predecessor-successor related) compliance rules may hinder widespread adoption and application in practice. Furthermore, hardly any of them has been evaluated in a real-world setting. We address this issue by applying a generic pattern matching approach for conceptual models to business process compliance checking in the financial sector. It consists of a model query language, a search algorithm and a corresponding modelling tool prototype. It is (1) applicable for all graph-based conceptual modeling languages and (2) for different kinds of compliance rules. Furthermore, based on an applicability check, we (3) evaluate the approach in a financial industry project setting against its relevance for decision support of audit and compliance management tasks.},
  language  = {en}
}
@article{BeckerDelfmannEggertetal.2012,
  author    = {Becker, J{\"o}rg and Delfmann, Patrick and Eggert, Mathias and Schwittay, Sebastian},
  title     = {Generalizability and Applicability of Model-Based Business Process Compliance-Checking Approaches — A State-of-the-Art Analysis and Research Roadmap},
  series = {Business Research : BuR},
  volume    = {5},
  journal   = {Business Research : BuR},
  number    = {2},
  publisher = {Springer},
  address   = {Heidelberg},
  issn      = {1866-8658},
  doi       = {10.1007/BF03342739},
  pages     = {221 -- 247},
  year      = {2012},
  abstract  = {With a steady increase of regulatory requirements for business processes, automation support of compliance management is a field garnering increasing attention in Information Systems research. Several approaches have been developed to support compliance checking of process models. One major challenge for such approaches is their ability to handle different modeling techniques and compliance rules in order to enable widespread adoption and application. Applying a structured literature search strategy, we reflect and discuss compliance-checking approaches in order to provide an insight into their generalizability and evaluation. The results imply that current approaches mainly focus on special modeling techniques and/or a restricted set of types of compliance rules. Most approaches abstain from real-world evaluation which raises the question of their practical applicability. Referring to the search results, we propose a roadmap for further research in model-based business process compliance checking.},
  language  = {en}
}
@incollection{YoshinobuKrauseMiyamotoetal.2018,
  author    = {Yoshinobu, Tatsuo and Krause, Steffi and Miyamoto, Ko-ichiro and Werner, Frederik and Poghossian, Arshak and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {(Bio-)chemical Sensing and Imaging by LAPS and SPIM},
  series = {Label-free biosensing: advanced materials, devices and applications},
  booktitle = {Label-free biosensing: advanced materials, devices and applications},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-75219-8},
  pages     = {103 -- 132},
  year      = {2018},
  abstract  = {The light-addressable potentiometric sensor (LAPS) and scanning photo-induced impedance microscopy (SPIM) are two closely related methods to visualise the distributions of chemical species and impedance, respectively, at the interface between the sensing surface and the sample solution. They both have the same field-effect structure based on a semiconductor, which allows spatially resolved and label-free measurement of chemical species and impedance in the form of a photocurrent signal generated by a scanning light beam. In this article, the principles and various operation modes of LAPS and SPIM, functionalisation of the sensing surface for measuring various species, LAPS-based chemical imaging and high-resolution sensors based on silicon-on-sapphire substrates are described and discussed, focusing on their technical details and prospective applications.},
  language  = {en}
}
@article{SchneiderTran2015,
  author    = {Schneider, Felix and Tran, Duc Hung},
  title     = {On the relation between the fair value option and bid-ask spreads: descriptive evidence on the recognition of credit risk changes under IFRS},
  series = {Journal of Business Economics},
  volume    = {85},
  journal   = {Journal of Business Economics},
  number    = {9},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1861-8928},
  doi       = {10.1007/s11573-015-0776-2},
  pages     = {1049 -- 1081},
  year      = {2015},
  language  = {en}
}
@article{Tran2011,
  author    = {Tran, Duc Hung},
  title     = {Corporate Governance und Eigenkapitalkosten - Bestandsaufnahme des Schrifttums unter besonderer Ber{\"u}cksichtigung des Informationsaspektes und Forschungsperspektiven},
  series = {Zeitschrift f{\"u}r Betriebswirtschaft},
  volume    = {81},
  journal   = {Zeitschrift f{\"u}r Betriebswirtschaft},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1861-8928},
  doi       = {10.1007/s11573-011-0461-z},
  pages     = {551 -- 585},
  year      = {2011},
  language  = {de}
}
@article{FingerBraunBil2018,
  author    = {Finger, Felix and Braun, Carsten and Bil, Cees},
  title     = {Impact of electric propulsion technology and mission requirements on the performance of VTOL UAVs},
  series = {CEAS Aeronautical Journal},
  volume    = {10},
  journal   = {CEAS Aeronautical Journal},
  number    = {3},
  publisher = {Springer},
  issn      = {1869-5582 print},
  doi       = {10.1007/s13272-018-0352-x},
  pages     = {843},
  year      = {2018},
  abstract  = {One of the engineering challenges in aviation is the design of transitioning vertical take-off and landing (VTOL) aircraft. Thrust-borne flight implies a higher mass fraction of the propulsion system, as well as much increased energy consumption in the take-off and landing phases. This mass increase is typically higher for aircraft with a separate lift propulsion system than for aircraft that use the cruise propulsion system to support a dedicated lift system. However, for a cost-benefit trade study, it is necessary to quantify the impact the VTOL requirement and propulsion configuration has on aircraft mass and size. For this reason, sizing studies are conducted. This paper explores the impact of considering a supplemental electric propulsion system for achieving hovering flight. Key variables in this study, apart from the lift system configuration, are the rotor disk loading and hover flight time, as well as the electrical systems technology level for both batteries and motors. Payload and endurance are typically used as the measures of merit for unmanned aircraft that carry electro-optical sensors, and therefore the analysis focuses on these particular parameters.},
  language  = {en}
}
@article{BergSchleserDelidovichetal.2018,
  author    = {Berg, Alexander-Karl and Schleser, Markus and Delidovich, Artem and Houben, Alexander},
  title     = {Ultraschallunterst{\"u}tzter Schmelzklebstoffauftrag},
  series = {adh{\"a}sion KLEBEN \& DICHTEN},
  volume    = {Volume 62},
  journal   = {adh{\"a}sion KLEBEN \& DICHTEN},
  number    = {Issue 12},
  publisher = {Springer},
  doi       = {10.1007/s35145-018-0089-z},
  pages     = {32 -- 37},
  year      = {2018},
  language  = {de}
}
@article{ViethEisenbeiss2011,
  author    = {Vieth, Matthias and Eisenbeiß, Maik},
  title     = {Die Geld-zur{\"u}ck-Garantie - Mehr als nur ein Qualit{\"a}tsindikator?},
  series = {Zeitschrift f{\"u}r Betriebswirtschaft},
  volume    = {81},
  journal   = {Zeitschrift f{\"u}r Betriebswirtschaft},
  number    = {12},
  publisher = {Springer},
  address   = {Berlin},
  doi       = {10.1007/s11573-011-0521-4},
  pages     = {1285 -- 1323},
  year      = {2011},
  abstract  = {Geld-zur{\"u}ck-Garantien erlangen in der Unternehmenspraxis eine immer gr{\"o}ßere Bedeutung, vor allem weil sie als probates Mittel zur Signalisierung hochwertiger Qualit{\"a}t angesehen werden - eine Annahme, die bislang wissenschaftlich ungepr{\"u}ft geblieben ist. Vor diesem Hintergrund wird im vorliegenden Beitrag eine umfassende empirische Untersuchung der kaufverhaltensrelevanten Wirkungen dieses Marketinginstrumentes vorgenommen. Die Ergebnisse verdeutlichen zum einen, dass eine Geld-zur{\"u}ck-Garantie nur unter bestimmten Bedingungen als Qualit{\"a}tssignal wirkt. Dies h{\"a}ngt neben der Art des Produktes (Erfahrungs- vs. Suchgut) insbesondere von der Auspr{\"a}gung des f{\"u}r die Qualit{\"a}tsbeurteilung besonders diagnostischen Merkmals Marke sowie von der Produktkenntnis der Konsumenten ab. Zum anderen zeigt sich aber auch, dass eine Geld-zur{\"u}ck-Garantie affektive Konsumentenreaktionen ausl{\"o}st, die die Kaufabsicht von Konsumenten zus{\"a}tzlich erh{\"o}hen k{\"o}nnen. Zusammenfassend stellen wir fest, dass eine Geld-zur{\"u}ck-Garantie - entgegen bisheriger Erwartungen aus der Praxis - nicht zwingend ein Qualit{\"a}tsindikator ist, stattdessen entfaltet sie aber bisher unbeachtete affektive Wirkungen, die insbesondere auf ihre absichernde Funktion von etwaigen Fehlentscheidungen beim Kauf zur{\"u}ckzuf{\"u}hren sind.},
  language  = {de}
}
@article{KramerValeroChansonetal.2019,
  author    = {Kramer, Matthias and Valero, Daniel and Chanson, Hubert and Bung, Daniel B.},
  title     = {Towards reliable turbulence estimations with phase-detection probes: an adaptive window cross-correlation technique},
  series = {Experiments in Fluids},
  volume    = {60},
  journal   = {Experiments in Fluids},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1432-1114},
  doi       = {10.1007/s00348-018-2650-9},
  year      = {2019},
  language  = {en}
}
@article{WilsonDickieSchreiteretal.2018,
  author    = {Wilson, C. E. and Dickie, A. P. and Schreiter, K. and Wehr, R. and Wilson, E. M. and Bial, J. and Scheer, Nico and Wilson, I. D. and Riley, R. J.},
  title     = {The pharmacokinetics and metabolism of diclofenac in chimeric humanized and murinized FRG mice},
  series = {Archives of Toxicology},
  volume    = {92},
  journal   = {Archives of Toxicology},
  number    = {6},
  publisher = {Springer},
  issn      = {1432-0738},
  doi       = {10.1007/s00204-018-2212-1},
  pages     = {1953 -- 1967},
  year      = {2018},
  abstract  = {The pharmacokinetics of diclofenac were investigated following single oral doses of 10 mg/kg to chimeric liver humanized and murinized FRG and C57BL/6 mice. In addition, the metabolism and excretion were investigated in chimeric liver humanized and murinized FRG mice. Diclofenac reached maximum blood concentrations of 2.43 ± 0.9 µg/mL (n = 3) at 0.25 h post-dose with an AUCinf of 3.67 µg h/mL and an effective half-life of 0.86 h (n = 2). In the murinized animals, maximum blood concentrations were determined as 3.86 ± 2.31 µg/mL at 0.25 h post-dose with an AUCinf of 4.94 ± 2.93 µg h/mL and a half-life of 0.52 ± 0.03 h (n = 3). In C57BL/6J mice, mean peak blood concentrations of 2.31 ± 0.53 µg/mL were seen 0.25 h post-dose with a mean AUCinf of 2.10 ± 0.49 µg h/mL and a half-life of 0.51 ± 0.49 h (n = 3). Analysis of blood indicated only trace quantities of drug-related material in chimeric humanized and murinized FRG mice. Metabolic profiling of urine, bile and faecal extracts revealed a complex pattern of metabolites for both humanized and murinized animals with, in addition to unchanged parent drug, a variety of hydroxylated and conjugated metabolites detected. The profiles in humanized mice were different to those of both murinized and wild-type animals, e.g., a higher proportion of the dose was detected in the form of acyl glucuronide metabolites and much reduced amounts as taurine conjugates. Comparison of the metabolic profiles obtained from the present study with previously published data from C57BL/6J mice and humans revealed a greater, though not complete, match between chimeric humanized mice and humans, such that the liver humanized FRG model may represent a model for assessing the biotransformation of such compounds in humans.},
  language  = {en}
}
@article{RauppSchmittWalzetal.2018,
  author    = {Raupp, Sebastian M. and Schmitt, Marcel and Walz, Anna-Lena and Diehm, Ralf and Hummel, Helga and Scharfer, Philip and Schabel, Wilhelm},
  title     = {Slot die stripe coating of low viscous fluids},
  series = {Journal of Coatings Technology and Research},
  volume    = {15},
  journal   = {Journal of Coatings Technology and Research},
  number    = {5},
  publisher = {Springer},
  issn      = {1935-3804},
  doi       = {10.1007/s11998-017-0039-y},
  pages     = {899 -- 911},
  year      = {2018},
  abstract  = {Slot die coating is applied to deposit thin and homogenous films in roll-to-roll and sheet-to-sheet applications. The critical step in operation is to choose suitable process parameters within the process window. In this work, we investigate an upper limit for stripe coatings. This maximum film thickness is characterized by stripe merging which needs to be avoided in a stable process. It is shown that the upper limit reduces the process window for stripe coatings to a major extent. As a result, stripe coatings at large coating gaps and low viscosities are only possible for relatively thick films. Explaining the upper limit, a theory of balancing the side pressure in the gap region in the cross-web direction has been developed.},
  language  = {en}
}
@incollection{DrummLemckeOberle2007,
  author    = {Drumm, Christian and Lemcke, Jens and Oberle, Daniel},
  title     = {Business Process Management And Semantic Technologies},
  series = {The Semantic Web},
  booktitle = {The Semantic Web},
  publisher = {Springer},
  address   = {Boston, MA},
  isbn      = {978-0-387-48531-7},
  doi       = {10.1007/978-0-387-48531-7_10},
  pages     = {207 -- 239},
  year      = {2007},
  language  = {en}
}
@incollection{MeskourisButenwegHinzenetal.2019,
  author    = {Meskouris, Konstantin and Butenweg, Christoph and Hinzen, Klaus-G. and H{\"o}ffer, R{\"u}diger},
  title     = {Stochasticity of Wind Processes and Spectral Analysis of Structural Gust Response},
  series = {Structural Dynamics with Applications in Earthquake and Wind Engineering},
  booktitle = {Structural Dynamics with Applications in Earthquake and Wind Engineering},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {978-3-662-57550-5 (Online)},
  doi       = {10.1007/978-3-662-57550-5_3},
  pages     = {153 -- 196},
  year      = {2019},
  abstract  = {Wind loads have great impact on many engineering structures. Wind storms often cause irreparable damage to the buildings which are exposed to it. Along with the earthquakes, wind represents one of the most common environmental load on structures and is relevant for limit state design. Modern wind codes indicate calculation procedures allowing engineers to deal with structural systems, which are susceptible to conduct wind-excited oscillations. In the codes approximate formulas for wind buffeting are specified which relate the dynamic problem to rather abstract parameter functions. The complete theory behind is not visible in order to simplify the applicability of the procedures. This chapter derives the underlying basic relations of the spectral method for wind buffeting and explains the main important applications of it in order to elucidate part of the theoretical background of computations after the new codes. The stochasticity of the wind processes is addressed, and the analysis of analytical as well as measurement based power spectra is outlined. Short MATLAB codes are added to the Appendix 3 which carry out the computation of a single sided auto-spectrum from a statistically stationary, discrete stochastic process. Two examples are presented.},
  language  = {en}
}
@incollection{DachwaldOhndorf2019,
  author    = {Dachwald, Bernd and Ohndorf, Andreas},
  title     = {Global optimization of continuous-thrust trajectories using evolutionary neurocontrol},
  series = {Modeling and Optimization in Space Engineering},
  booktitle = {Modeling and Optimization in Space Engineering},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-10501-3},
  doi       = {10.1007/978-3-030-10501-3_2},
  pages     = {33 -- 57},
  year      = {2019},
  abstract  = {Searching optimal continuous-thrust trajectories is usually a difficult and time-consuming task. The solution quality of traditional optimal-control methods depends strongly on an adequate initial guess because the solution is typically close to the initial guess, which may be far from the (unknown) global optimum. Evolutionary neurocontrol attacks continuous-thrust optimization problems from the perspective of artificial intelligence and machine learning, combining artificial neural networks and evolutionary algorithms. This chapter describes the method and shows some example results for single- and multi-phase continuous-thrust trajectory optimization problems to assess its performance. Evolutionary neurocontrol can explore the trajectory search space more exhaustively than a human expert can do with traditional optimal-control methods. Especially for difficult problems, it usually finds solutions that are closer to the global optimum. Another fundamental advantage is that continuous-thrust trajectories can be optimized without an initial guess and without expert supervision.},
  language  = {en}
}
@article{VoegeleRuebbelkeGovorukhaetal.2019,
  author    = {V{\"o}gele, Stefan and R{\"u}bbelke, Dirk and Govorukha, Kristina and Grajewski, Matthias},
  title     = {Socio-technical scenarios for energy-intensive industries: the future of steel production in Germany},
  series = {Climatic Change},
  journal   = {Climatic Change},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0165-0009},
  doi       = {10.1007/s10584-019-02366-0},
  pages     = {1 -- 16},
  year      = {2019},
  language  = {en}
}
@incollection{Eggert2019,
  author    = {Eggert, Mathias},
  title     = {Big Data Research - How to Structure the Changes of the Past Decade?},
  series = {The Art of Structuring},
  booktitle = {The Art of Structuring},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-06234-7},
  doi       = {10.1007/978-3-030-06234-7_26},
  pages     = {271 -- 281},
  year      = {2019},
  abstract  = {In the past decade, many IS researchers focused on researching the phenomenon of Big Data. At the same time, the relevance of data protection gets more attention than ever before. In particular, since the enactment of the European General Data Protection Regulation in May 2018 Information Systems research should provide answers for protecting personal data. The article at hand presents a structuring framework for Big Data research outcome and the consideration of data protection. IS Researchers might use the framework in order to structure Big Data literature and to identify research gaps that should be addressed in the future.},
  language  = {en}
}
@incollection{FranzenSteckenPfaffetal.2019,
  author    = {Franzen, Julian and Stecken, Jannis and Pfaff, Raphael and Kuhlenk{\"o}tter, Bernd},
  title     = {Using the Digital Shadow for a Prescriptive Optimization of Maintenance and Operation : The Locomotive in the Context of the Cyber-Physical System},
  series = {Advances in Production, Logistics and Traffic},
  booktitle = {Advances in Production, Logistics and Traffic},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-13535-5},
  doi       = {10.1007/978-3-030-13535-5_19},
  pages     = {265 -- 276},
  year      = {2019},
  abstract  = {In competition with other modes of transport, rail freight transport is looking for solutions to become more attractive. Short-term success can be achieved through the data-driven optimization of operations and maintenance as well as the application of novel strategies such as prescriptive maintenance. After introducing the concept of prescriptive maintenance, this paper aims to prove that vehicle-focused applications of this approach indeed have the potential to increase attractiveness. However, even greater advantages can be activated if data from the horizontal network of the vehicle is available. Drawing on the state of the art in research and technology in the field of cyber-physical systems (CPS) as well as digital twins and shadows, our work serves to design a system of systems for the horizontal interconnection of a rail vehicle and to conceptualize a draft for a digital twin of a locomotive.},
  language  = {en}
}
@article{SchildtBraunMarzocca2019,
  author    = {Schildt, Ph. and Braun, Carsten and Marzocca, P.},
  title     = {Metric evaluating potentials of condition-monitoring approaches for hybrid electric aircraft propulsion systems},
  series = {CEAS Aeronautical Journal},
  journal   = {CEAS Aeronautical Journal},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1869-5590},
  doi       = {10.1007/s13272-019-00411-3},
  pages     = {1 -- 14},
  year      = {2019},
  language  = {en}
}
@incollection{RaoPathroseHueningetal.2019,
  author    = {Rao, Deepak and Pathrose, Plato and H{\"u}ning, Felix and Sid, Jithin},
  title     = {An Approach for Validating Safety of Perception Software in Autonomous Driving Systems},
  series = {Model-Based Safety and Assessment: 6th International Symposium, IMBSA 2019, Thessaloniki, Greece, October 16-18, 2019, Proceedings},
  booktitle = {Model-Based Safety and Assessment: 6th International Symposium, IMBSA 2019, Thessaloniki, Greece, October 16-18, 2019, Proceedings},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-32872-6},
  doi       = {10.1007/978-3-030-32872-6_20},
  pages     = {303 -- 316},
  year      = {2019},
  abstract  = {The increasing complexity of Advanced Driver Assistance Systems (ADAS) presents a challenging task to validate safe and reliable performance of these systems under varied conditions. The test and validation of ADAS/AD with real test drives, although important, involves huge costs and time. Simulation tools provide an alternative with the added advantage of reproducibility but often use ideal sensors, which do not reflect real sensor output accurately. This paper presents a new validation methodology using fault injection, as recommended by the ISO 26262 standard, to test software and system robustness. In our work, we investigated and developed a tool capable of inserting faults at different software and system levels to verify its robustness. The scope of this paper is to cover the fault injection test for the Visteon's DriveCore™ system, a centralized domain controller for Autonomous driving which is sensor agnostic and SoC agnostic. With this new approach, the validation of safety monitoring functionality and its behavior can be tested using real-world data instead of synthetic data from simulation tools resulting in having better confidence in system performance before proceeding with in-vehicle testing.},
  language  = {en}
}
@article{Stulpe2019,
  author    = {Stulpe, Werner},
  title     = {Aspects of the Quantum-Classical Connection Based on Statistical Maps},
  series = {Foundations of Physics},
  volume    = {49},
  journal   = {Foundations of Physics},
  number    = {6},
  publisher = {Springer},
  address   = {Berlin},
  doi       = {10.1007/s10701-019-00269-9},
  pages     = {677 -- 692},
  year      = {2019},
  language  = {en}
}
@article{KromeHoeftSander2019,
  author    = {Krome, Cornelia and H{\"o}ft, Jan and Sander, Volker},
  title     = {Clustering time series applied to energy markets},
  series = {Energy Informatics},
  volume    = {2},
  journal   = {Energy Informatics},
  number    = {Article numer 17},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {2520-8942},
  doi       = {10.1186/s42162-019-0076-0},
  pages     = {1 -- 20},
  year      = {2019},
  language  = {en}
}
@article{GronsfeldJoachimMalecha2019,
  author    = {Gronsfeld, Richard and Joachim, Klubert and Malecha, Hartmut},
  title     = {3-D-Visualisierung von vorhandenen Staubauwerken zur holistischen Planung und {\"U}berwachung},
  series = {Wasserwirtschaft},
  volume    = {109},
  journal   = {Wasserwirtschaft},
  number    = {5},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {2192-8762},
  doi       = {10.1007/s35147-019-0075-x},
  pages     = {82 -- 85},
  year      = {2019},
  language  = {de}
}
@article{OrzadaFiedlerBitzetal.2020,
  author    = {Orzada, Stephan and Fiedler, Thomas M. and Bitz, Andreas and Ladd, Mark E. and Quick, Harald H.},
  title     = {Local SAR compression with overestimation control to reduce maximum relative SAR overestimation and improve multi-channel RF array performance},
  series = {Magnetic Resonance Materials in Physics, Biology and Medicine},
  journal   = {Magnetic Resonance Materials in Physics, Biology and Medicine},
  number    = {34 (2021)},
  publisher = {Springer},
  address   = {Heidelberg},
  isbn      = {1352-8661},
  doi       = {10.1007/s10334-020-00890-0},
  pages     = {153 -- 164},
  year      = {2020},
  abstract  = {Objective In local SAR compression algorithms, the overestimation is generally not linearly dependent on actual local SAR. This can lead to large relative overestimation at low actual SAR values, unnecessarily constraining transmit array performance. Method Two strategies are proposed to reduce maximum relative overestimation for a given number of VOPs. The first strategy uses an overestimation matrix that roughly approximates actual local SAR; the second strategy uses a small set of pre-calculated VOPs as the overestimation term for the compression. Result Comparison with a previous method shows that for a given maximum relative overestimation the number of VOPs can be reduced by around 20\% at the cost of a higher absolute overestimation at high actual local SAR values. Conclusion The proposed strategies outperform a previously published strategy and can improve the SAR compression where maximum relative overestimation constrains the performance of parallel transmission.},
  language  = {en}
}
@article{MayerHentschkeHageretal.2017,
  author    = {Mayer, Jan and Hentschke, Reinhard and Hager, Jonathan and Hojdis, Nils and Karimi-Varnaneh, Hossein Ali},
  title     = {A Nano-Mechanical Instability as Primary Contribution to Rolling Resistance},
  series = {Scientific Reports},
  volume    = {7},
  journal   = {Scientific Reports},
  number    = {Article number 11275},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {2045-2322},
  year      = {2017},
  language  = {en}
}
@article{HarishWriggersJungketal.2016,
  author    = {Harish, Ajay B. and Wriggers, Peter and Jungk, Juliane and Hojdis, Nils and Recker, Carla},
  title     = {Mesoscale Constitutive Modeling of Non-Crystallizing Filled Elastomers},
  series = {Computational Mechanics},
  volume    = {57},
  journal   = {Computational Mechanics},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1432-0924},
  doi       = {10.1007/s00466-015-1251-1},
  pages     = {653 -- 677},
  year      = {2016},
  abstract  = {Elastomers are exceptional materials owing to their ability to undergo large deformations before failure. However, due to their very low stiffness, they are not always suitable for industrial applications. Addition of filler particles provides reinforcing effects and thus enhances the material properties that render them more versatile for applications like tyres etc. However, deformation behavior of filled polymers is accompanied by several nonlinear effects like Mullins and Payne effect. To this day, the physical and chemical changes resulting in such nonlinear effect remain an active area of research. In this work, we develop a heterogeneous (or multiphase) constitutive model at the mesoscale explicitly considering filler particle aggregates, elastomeric matrix and their mechanical interaction through an approximate interface layer. The developed constitutive model is used to demonstrate cluster breakage, also, as one of the possible sources for Mullins effect observed in non-crystallizing filled elastomers.},
  language  = {en}
}
@inproceedings{LorenzAltherrPelz2020,
  author    = {Lorenz, Imke-Sophie and Altherr, Lena and Pelz, Peter F.},
  title     = {Assessing and Optimizing the Resilience of Water Distribution Systems Using Graph-Theoretical Metrics},
  series = {Operations Research Proceedings 2019},
  booktitle = {Operations Research Proceedings 2019},
  editor    = {Neufeld, Janis S. and Buscher, Udo and Lasch, Rainer and M{\"o}st, Dominik and Sch{\"o}nberger, J{\"o}rn},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-48439-2},
  doi       = {10.1007/978-3-030-48439-2_63},
  pages     = {521 -- 527},
  year      = {2020},
  abstract  = {Water distribution systems are an essential supply infrastructure for cities. Given that climatic and demographic influences will pose further challenges for these infrastructures in the future, the resilience of water supply systems, i.e. their ability to withstand and recover from disruptions, has recently become a subject of research. To assess the resilience of a WDS, different graph-theoretical approaches exist. Next to general metrics characterizing the network topology, also hydraulic and technical restrictions have to be taken into account. In this work, the resilience of an exemplary water distribution network of a major German city is assessed, and a Mixed-Integer Program is presented which allows to assess the impact of capacity adaptations on its resilience.},
  language  = {en}
}
@inproceedings{LeiseSimonAltherr2020,
  author    = {Leise, Philipp and Simon, Nicolai and Altherr, Lena},
  title     = {Comparison of Piecewise Linearization Techniques to Model Electric Motor Efficiency Maps: A Computational Study},
  series = {Operations Research Proceedings 2019},
  booktitle = {Operations Research Proceedings 2019},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-48439-2},
  doi       = {10.1007/978-3-030-48439-2_55},
  pages     = {457 -- 463},
  year      = {2020},
  abstract  = {To maximize the travel distances of battery electric vehicles such as cars or buses for a given amount of stored energy, their powertrains are optimized energetically. One key part within optimization models for electric powertrains is the efficiency map of the electric motor. The underlying function is usually highly nonlinear and nonconvex and leads to major challenges within a global optimization process. To enable faster solution times, one possibility is the usage of piecewise linearization techniques to approximate the nonlinear efficiency map with linear constraints. Therefore, we evaluate the influence of different piecewise linearization modeling techniques on the overall solution process and compare the solution time and accuracy for methods with and without explicitly used binary variables.},
  language  = {en}
}
@incollection{AltherrEdererLorenzetal.2016,
  author    = {Altherr, Lena and Ederer, Thorsten and Lorenz, Ulf and Pelz, Peter F. and P{\"o}ttgen, Philipp},
  title     = {Designing a feedback control system via mixed-integer programming},
  series = {Operations Research Proceedings 2014: Selected Papers of the Annual International Conference of the German Operations Research},
  booktitle = {Operations Research Proceedings 2014: Selected Papers of the Annual International Conference of the German Operations Research},
  editor    = {L{\"u}bbecke, Marco E. and Koster, Arie and Letmathe, Peter and Madlener, Reihard and Preis, Britta and Walther, Grit},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-28695-2},
  doi       = {10.1007/978-3-319-28697-6_18},
  pages     = {121 -- 127},
  year      = {2016},
  abstract  = {Pure analytical or experimental methods can only find a control strategy for technical systems with a fixed setup. In former contributions we presented an approach that simultaneously finds the optimal topology and the optimal open-loop control of a system via Mixed Integer Linear Programming (MILP). In order to extend this approach by a closed-loop control we present a Mixed Integer Program for a time discretized tank level control. This model is the basis for an extension by combinatorial decisions and thus for the variation of the network topology. Furthermore, one is able to appraise feasible solutions using the global optimality gap.},
  language  = {en}
}
@incollection{Kotliar2021,
  author    = {Kotliar, Konstantin},
  title     = {Ocular rigidity: clinical approach},
  series = {Ocular Rigidity, Biomechanics and Hydrodynamics of the Eye},
  booktitle = {Ocular Rigidity, Biomechanics and Hydrodynamics of the Eye},
  editor    = {Pallikaris, I. and Tsilimbaris, M. K. and Dastiridou, A. I.},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-64422-2},
  doi       = {10.1007/978-3-030-64422-2_2},
  pages     = {15 -- 43},
  year      = {2021},
  abstract  = {The term ocular rigidity is widely used in clinical ophthalmology. Generally it is assumed as a resistance of the whole eyeball to mechanical deformation and relates to biomechanical properties of the eye and its tissues. Basic principles and formulas for clinical tonometry, tonography and pulsatile ocular blood flow measurements are based on the concept of ocular rigidity. There is evidence for altered ocular rigidity in aging, in several eye diseases and after eye surgery. Unfortunately, there is no consensual view on ocular rigidity: it used to make a quite different sense for different people but still the same name. Foremost there is no clear consent between biomechanical engineers and ophthalmologists on the concept. Moreover ocular rigidity is occasionally characterized using various parameters with their different physical dimensions. In contrast to engineering approach, clinical approach to ocular rigidity claims to characterize the total mechanical response of the eyeball to its deformation without any detailed considerations on eye morphology or material properties of its tissues. Further to the previous chapter this section aims to describe clinical approach to ocular rigidity from the perspective of an engineer in an attempt to straighten out this concept, to show its advantages, disadvantages and various applications.},
  language  = {en}
}
@article{KuertenKotliarFuestetal.2021,
  author    = {Kuerten, David and Kotliar, Konstantin and Fuest, Matthias and Walter, Peter and Hollstein, Muriel and Plange, Niklas},
  title     = {Does hemispheric vascular regulation differ significantly in glaucoma patients with altitudinal visual field asymmetry? A single-center, prospective study},
  series = {International Ophthalmology},
  volume    = {41},
  journal   = {International Ophthalmology},
  number    = {41},
  editor    = {Neri, Piergiorgio},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {1573-2630},
  doi       = {10.1007/s10792-021-01876-0},
  pages     = {3109 -- 3119},
  year      = {2021},
  abstract  = {Purpose Vascular risk factors and ocular perfusion are heatedly discussed in the pathogenesis of glaucoma. The retinal vessel analyzer (RVA, IMEDOS Systems, Germany) allows noninvasive measurement of retinal vessel regulation. Significant differences especially in the veins between healthy subjects and patients suffering from glaucoma were previously reported. In this pilot-study we investigated if localized vascular regulation is altered in glaucoma patients with altitudinal visual field defect asymmetry. Methods 15 eyes of 12 glaucoma patients with advanced altitudinal visual field defect asymmetry were included. The mean defect was calculated for each hemisphere separately (-20.99 ± 10.49 pro- found hemispheric visual field defect vs -7.36 ± 3.97 dB less profound hemisphere). After pupil dilation, RVA measurements of retinal arteries and veins were conducted using the standard protocol. The superior and inferior retinal vessel reactivity were measured consecutively in each eye. Results Significant differences were recorded in venous vessel constriction after flicker light stimulation and overall amplitude of the reaction (p \ 0.04 and p \ 0.02 respectively) in-between the hemispheres spheres. Vessel reaction was higher in the hemisphere corresponding to the more advanced visual field defect. Arterial diameters reacted similarly, failing to reach statistical significance. Conclusion Localized retinal vessel regulation is significantly altered in glaucoma patients with asymmetri altitudinal visual field defects. Veins supplying the hemisphere concordant to a less profound visual field defect show diminished diameter changes. Vascular dysregulation might be particularly important in early glaucoma stages prior to a significant visual field defect.},
  language  = {en}
}
@incollection{PfetschAbeleAltherretal.2021,
  author    = {Pfetsch, Marc E. and Abele, Eberhard and Altherr, Lena and B{\"o}lling, Christian and Br{\"o}tz, Nicolas and Dietrich, Ingo and Gally, Tristan and Geßner, Felix and Groche, Peter and Hoppe, Florian and Kirchner, Eckhard and Kloberdanz, Hermann and Knoll, Maximilian and Kolvenbach, Philip and Kuttich-Meinlschmidt, Anja and Leise, Philipp and Lorenz, Ulf and Matei, Alexander and Molitor, Dirk A. and Niessen, Pia and Pelz, Peter F. and Rexer, Manuel and Schmitt, Andreas and Schmitt, Johann M. and Schulte, Fiona and Ulbrich, Stefan and Weigold, Matthias},
  title     = {Strategies for mastering uncertainty},
  series = {Mastering uncertainty in mechanical engineering},
  booktitle = {Mastering uncertainty in mechanical engineering},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-78353-2},
  doi       = {10.1007/978-3-030-78354-9_6},
  pages     = {365 -- 456},
  year      = {2021},
  abstract  = {This chapter describes three general strategies to master uncertainty in technical systems: robustness, flexibility and resilience. It builds on the previous chapters about methods to analyse and identify uncertainty and may rely on the availability of technologies for particular systems, such as active components. Robustness aims for the design of technical systems that are insensitive to anticipated uncertainties. Flexibility increases the ability of a system to work under different situations. Resilience extends this characteristic by requiring a given minimal functional performance, even after disturbances or failure of system components, and it may incorporate recovery. The three strategies are described and discussed in turn. Moreover, they are demonstrated on specific technical systems.},
  language  = {en}
}
@inproceedings{MuellerSchmittLeiseetal.2021,
  author    = {M{\"u}ller, Tim M. and Schmitt, Andreas and Leise, Philipp and Meck, Tobias and Altherr, Lena and Pelz, Peter F. and Pfetsch, Marc E.},
  title     = {Validation of an optimized resilient water supply system},
  series = {Uncertainty in Mechanical Engineering},
  booktitle = {Uncertainty in Mechanical Engineering},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-77255-0},
  doi       = {10.1007/978-3-030-77256-7_7},
  pages     = {70 -- 80},
  year      = {2021},
  abstract  = {Component failures within water supply systems can lead to significant performance losses. One way to address these losses is the explicit anticipation of failures within the design process. We consider a water supply system for high-rise buildings, where pump failures are the most likely failure scenarios. We explicitly consider these failures within an early design stage which leads to a more resilient system, i.e., a system which is able to operate under a predefined number of arbitrary pump failures. We use a mathematical optimization approach to compute such a resilient design. This is based on a multi-stage model for topology optimization, which can be described by a system of nonlinear inequalities and integrality constraints. Such a model has to be both computationally tractable and to represent the real-world system accurately. We therefore validate the algorithmic solutions using experiments on a scaled test rig for high-rise buildings. The test rig allows for an arbitrary connection of pumps to reproduce scaled versions of booster station designs for high-rise buildings. We experimentally verify the applicability of the presented optimization model and that the proposed resilience properties are also fulfilled in real systems.},
  language  = {en}
}
@incollection{LeiseAltherrSimonetal.2019,
  author    = {Leise, Philipp and Altherr, Lena and Simon, Nicolai and Pelz, Peter F.},
  title     = {Finding global-optimal gearbox designs for battery electric vehicles},
  series = {Optimization of complex systems - theory, models, algorithms and applications : WCGO 2019},
  booktitle = {Optimization of complex systems - theory, models, algorithms and applications : WCGO 2019},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-21802-7},
  doi       = {10.1007/978-3-030-21803-4_91},
  pages     = {916 -- 925},
  year      = {2019},
  abstract  = {In order to maximize the possible travel distance of battery electric vehicles with one battery charge, it is mandatory to adjust all components of the powertrain carefully to each other. While current vehicle designs mostly simplify the powertrain rigorously and use an electric motor in combination with a gearbox with only one fixed transmission ratio, the use of multi-gear systems has great potential. First, a multi-speed system is able to improve the overall energy efficiency. Secondly, it is able to reduce the maximum momentum and therefore to reduce the maximum current provided by the traction battery, which results in a longer battery lifetime. In this paper, we present a systematic way to generate multi-gear gearbox designs that—combined with a certain electric motor—lead to the most efficient fulfillment of predefined load scenarios and are at the same time robust to uncertainties in the load. Therefore, we model the electric motor and the gearbox within a Mixed-Integer Nonlinear Program, and optimize the efficiency of the mechanical parts of the powertrain. By combining this mathematical optimization program with an unsupervised machine learning algorithm, we are able to derive global-optimal gearbox designs for practically relevant momentum and speed requirements.},
  language  = {en}
}
@incollection{StengerAltherrAbel2019,
  author    = {Stenger, David and Altherr, Lena and Abel, Dirk},
  title     = {Machine learning and metaheuristics for black-box optimization of product families: a case-study investigating solution quality vs. computational overhead},
  series = {Operations Research Proceedings 2018},
  booktitle = {Operations Research Proceedings 2018},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-18499-5 (Print)},
  doi       = {10.1007/978-3-030-18500-8_47},
  pages     = {379 -- 385},
  year      = {2019},
  abstract  = {In product development, numerous design decisions have to be made. Multi-domain virtual prototyping provides a variety of tools to assess technical feasibility of design options, however often requires substantial computational effort for just a single evaluation. A special challenge is therefore the optimal design of product families, which consist of a group of products derived from a common platform. Finding an optimal platform configuration (stating what is shared and what is individually designed for each product) and an optimal design of all products simultaneously leads to a mixed-integer nonlinear black-box optimization model. We present an optimization approach based on metamodels and a metaheuristic. To increase computational efficiency and solution quality, we compare different types of Gaussian process regression metamodels adapted from the domain of machine learning, and combine them with a genetic algorithm. We illustrate our approach on the example of a product family of electrical drives, and investigate the trade-off between solution quality and computational overhead.},
  language  = {en}
}
@incollection{MuellerAltherrAholaetal.2018,
  author    = {M{\"u}ller, Tim M. and Altherr, Lena and Ahola, Marja and Schabel, Samuel and Pelz, Peter F.},
  title     = {Optimizing pressure screen systems in paper recycling: optimal system layout, component selection and operation},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-18499-5},
  doi       = {10.1007/978-3-030-18500-8_44},
  pages     = {355 -- 361},
  year      = {2018},
  abstract  = {Around 60\% of the paper worldwide is made from recovered paper. Especially adhesive contaminants, so called stickies, reduce paper quality. To remove stickies but at the same time keep as many valuable fibers as possible, multi-stage screening systems with several interconnected pressure screens are used. When planning such systems, suitable screens have to be selected and their interconnection as well as operational parameters have to be defined considering multiple conflicting objectives. In this contribution, we present a Mixed-Integer Nonlinear Program to optimize system layout, component selection and operation to find a suitable trade-off between output quality and yield.},
  language  = {en}
}
@inproceedings{MeckMuellerAltherretal.2020,
  author    = {Meck, Marvin M. and M{\"u}ller, Tim M. and Altherr, Lena and Pelz, Peter F.},
  title     = {Improving an industrial cooling system using MINLP, considering capital and operating costs},
  series = {Operations Research Proceedings 2019},
  booktitle = {Operations Research Proceedings 2019},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-48438-5 (Print)},
  doi       = {10.1007/978-3-030-48439-2_61},
  pages     = {505 -- 512},
  year      = {2020},
  abstract  = {The chemical industry is one of the most important industrial sectors in Germany in terms of manufacturing revenue. While thermodynamic boundary conditions often restrict the scope for reducing the energy consumption of core processes, secondary processes such as cooling offer scope for energy optimisation. In this contribution, we therefore model and optimise an existing cooling system. The technical boundary conditions of the model are provided by the operators, the German chemical company BASF SE. In order to systematically evaluate different degrees of freedom in topology and operation, we formulate and solve a Mixed-Integer Nonlinear Program (MINLP), and compare our optimisation results with the existing system.},
  language  = {en}
}
@article{MuellerLeiseLorenzetal.2020,
  author    = {M{\"u}ller, Tim M. and Leise, Philipp and Lorenz, Imke-Sophie and Altherr, Lena and Pelz, Peter F.},
  title     = {Optimization and validation of pumping system design and operation for water supply in high-rise buildings},
  series = {Optimization and Engineering},
  volume    = {2021},
  journal   = {Optimization and Engineering},
  number    = {22},
  publisher = {Springer},
  issn      = {1573-2924},
  doi       = {10.1007/s11081-020-09553-4},
  pages     = {643 -- 686},
  year      = {2020},
  abstract  = {The application of mathematical optimization methods for water supply system design and operation provides the capacity to increase the energy efficiency and to lower the investment costs considerably. We present a system approach for the optimal design and operation of pumping systems in real-world high-rise buildings that is based on the usage of mixed-integer nonlinear and mixed-integer linear modeling approaches. In addition, we consider different booster station topologies, i.e. parallel and series-parallel central booster stations as well as decentral booster stations. To confirm the validity of the underlying optimization models with real-world system behavior, we additionally present validation results based on experiments conducted on a modularly constructed pumping test rig. Within the models we consider layout and control decisions for different load scenarios, leading to a Deterministic Equivalent of a two-stage stochastic optimization program. We use a piecewise linearization as well as a piecewise relaxation of the pumps' characteristics to derive mixed-integer linear models. Besides the solution with off-the-shelf solvers, we present a problem specific exact solving algorithm to improve the computation time. Focusing on the efficient exploration of the solution space, we divide the problem into smaller subproblems, which partly can be cut off in the solution process. Furthermore, we discuss the performance and applicability of the solution approaches for real buildings and analyze the technical aspects of the solutions from an engineer's point of view, keeping in mind the economically important trade-off between investment and operation costs.},
  language  = {en}
}
@incollection{StengerAltherrMuelleretal.2018,
  author    = {Stenger, David and Altherr, Lena and M{\"u}ller, Tankred and Pelz, Peter F.},
  title     = {Product family design optimization using model-based engineering techniques},
  series = {Operations Research Proceedings 2017},
  booktitle = {Operations Research Proceedings 2017},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-89919-0},
  doi       = {10.1007/978-3-319-89920-6_66},
  pages     = {495 -- 502},
  year      = {2018},
  abstract  = {Highly competitive markets paired with tremendous production volumes demand particularly cost efficient products. The usage of common parts and modules across product families can potentially reduce production costs. Yet, increasing commonality typically results in overdesign of individual products. Multi domain virtual prototyping enables designers to evaluate costs and technical feasibility of different single product designs at reasonable computational effort in early design phases. However, savings by platform commonality are hard to quantify and require detailed knowledge of e.g. the production process and the supply chain. Therefore, we present and evaluate a multi-objective metamodel-based optimization algorithm which enables designers to explore the trade-off between high commonality and cost optimal design of single products.},
  language  = {en}
}
@incollection{AltherrDoerigEdereretal.2017,
  author    = {Altherr, Lena and D{\"o}rig, Bastian and Ederer, Thorsten and Pelz, Peter Franz and Pfetsch, Marc and Wolf, Jan},
  title     = {A mixed-integer nonlinear program for the design of gearboxes},
  series = {Operations Research Proceedings 2016},
  booktitle = {Operations Research Proceedings 2016},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-55701-4},
  doi       = {10.1007/978-3-319-55702-1_31},
  pages     = {227 -- 233},
  year      = {2017},
  abstract  = {Gearboxes are mechanical transmission systems that provide speed and torque conversions from a rotating power source. Being a central element of the drive train, they are relevant for the efficiency and durability of motor vehicles. In this work, we present a new approach for gearbox design: Modeling the design problem as a mixed-integer nonlinear program (MINLP) allows us to create gearbox designs from scratch for arbitrary requirements and—given enough time—to compute provably globally optimal designs for a given objective. We show how different degrees of freedom influence the runtime and present an exemplary solution.},
  language  = {en}
}
@incollection{LeiseAltherrPelz2018,
  author    = {Leise, Philipp and Altherr, Lena and Pelz, Peter F.},
  title     = {Energy-Efficient design of a water supply system for skyscrapers by mixed-integer nonlinear programming},
  series = {Operations Research Proceedings 2017},
  booktitle = {Operations Research Proceedings 2017},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-89919-0},
  doi       = {10.1007/978-3-319-89920-6_63},
  year      = {2018},
  abstract  = {The energy-efficiency of technical systems can be improved by a systematic design approach. Technical Operations Research (TOR) employs methods known from Operations Research to find a global optimal layout and operation strategy of technical systems. We show the practical usage of this approach by the systematic design of a decentralized water supply system for skyscrapers. All possible network options and operation strategies are modeled by a Mixed-Integer Nonlinear Program. We present the optimal system found by our approach and highlight the energy savings compared to a conventional system design.},
  language  = {en}
}
@inproceedings{RauschFriesenAltherretal.2018,
  author    = {Rausch, Lea and Friesen, John and Altherr, Lena and Pelz, Peter F.},
  title     = {Using mixed-integer programming for the optimal design of water supply networks for slums},
  series = {Operations Research Proceedings 2017},
  booktitle = {Operations Research Proceedings 2017},
  editor    = {Kliewer, Natalia and Ehmke, Jan Fabian and Bornd{\"o}rfer, Ralf},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-89919-0 (Print)},
  doi       = {10.1007/978-3-319-89920-6_68},
  pages     = {509 -- 516},
  year      = {2018},
  abstract  = {The UN sets the goal to ensure access to water and sanitation for all people by 2030. To address this goal, we present a multidisciplinary approach for designing water supply networks for slums in large cities by applying mathematical optimization. The problem is modeled as a mixed-integer linear problem (MILP) aiming to find a network describing the optimal supply infrastructure. To illustrate the approach, we apply it on a small slum cluster in Dhaka, Bangladesh.},
  language  = {en}
}
@article{LenzKahmannBehbahanietal.2022,
  author    = {Lenz, Maximilian and Kahmann, Stephanie Lucina and Behbahani, Mehdi and Pennig, Lenhard and Hackl, Michael and Leschinger, Tim and M{\"u}ller, Lars Peter and Wegmann, Kilian},
  title     = {Influence of rotator cuff preload on fracture configuration in proximal humerus fractures: a proof of concept for fracture simulation},
  series = {Archives of Orthopaedic and Trauma Surgery},
  journal   = {Archives of Orthopaedic and Trauma Surgery},
  publisher = {Springer},
  address   = {Berlin, Heidelberg},
  issn      = {1434-3916},
  doi       = {10.1007/s00402-022-04471-9},
  year      = {2022},
  abstract  = {Introduction In regard of surgical training, the reproducible simulation of life-like proximal humerus fractures in human cadaveric specimens is desirable. The aim of the present study was to develop a technique that allows simulation of realistic proximal humerus fractures and to analyse the influence of rotator cuff preload on the generated lesions in regards of fracture configuration. Materials and methods Ten cadaveric specimens (6 left, 4 right) were fractured using a custom-made drop-test bench, in two groups. Five specimens were fractured without rotator cuff preload, while the other five were fractured with the tendons of the rotator cuff preloaded with 2 kg each. The humeral shaft and the shortened scapula were potted. The humerus was positioned at 90° of abduction and 10° of internal rotation to simulate a fall on the elevated arm. In two specimens of each group, the emergence of the fractures was documented with high-speed video imaging. Pre-fracture radiographs were taken to evaluate the deltoid-tuberosity index as a measure of bone density. Post-fracture X-rays and CT scans were performed to define the exact fracture configurations. Neer's classification was used to analyse the fractures. Results In all ten cadaveric specimens life-like proximal humerus fractures were achieved. Two III-part and three IV-part fractures resulted in each group. The preloading of the rotator cuff muscles had no further influence on the fracture configuration. High-speed videos of the fracture simulation revealed identical fracture mechanisms for both groups. We observed a two-step fracture mechanism, with initial impaction of the head segment against the glenoid followed by fracturing of the head and the tuberosities and then with further impaction of the shaft against the acromion, which lead to separation of the tuberosities. Conclusion A high energetic axial impulse can reliably induce realistic proximal humerus fractures in cadaveric specimens. The preload of the rotator cuff muscles had no influence on initial fracture configuration. Therefore, fracture simulation in the proximal humerus is less elaborate. Using the presented technique, pre-fractured specimens are available for real-life surgical education.},
  language  = {en}
}
@article{SchneiderSchwabedalBialonski2022,
  author    = {Schneider, Jules and Schwabedal, Justus T. C. and Bialonski, Stephan},
  title     = {Schlafspindeln - Funktion, Detektion und Nutzung als Biomarker f{\"u}r die psychiatrische Diagnostik},
  series = {Der Nervenarzt},
  journal   = {Der Nervenarzt},
  publisher = {Springer},
  address   = {Berlin, Heidelberg},
  issn      = {1433-0407},
  doi       = {10.1007/s00115-022-01340-z},
  pages     = {1 -- 8},
  year      = {2022},
  abstract  = {Hintergrund: Die Schlafspindel ist ein Graphoelement des Elektroenzephalogramms (EEG), das im Leicht- und Tiefschlaf beobachtet werden kann. Ver{\"a}nderungen der Spindelaktivit{\"a}t wurden f{\"u}r verschiedene psychiatrische Erkrankungen beschrieben. Schlafspindeln zeigen aufgrund ihrer relativ konstanten Eigenschaften Potenzial als Biomarker in der psychiatrischen Diagnostik. Methode: Dieser Beitrag liefert einen {\"U}berblick {\"u}ber den Stand der Wissenschaft zu Eigenschaften und Funktionen der Schlafspindeln sowie {\"u}ber beschriebene Ver{\"a}nderungen der Spindelaktivit{\"a}t bei psychiatrischen Erkrankungen. Verschiedene methodische Ans{\"a}tze und Ausblicke zur Spindeldetektion werden hinsichtlich deren Anwendungspotenzial in der psychiatrischen Diagnostik erl{\"a}utert. Ergebnisse und Schlussfolgerung: W{\"a}hrend Ver{\"a}nderungen der Spindelaktivit{\"a}t bei psychiatrischen Erkrankungen beschrieben wurden, ist deren exaktes Potenzial f{\"u}r die psychiatrische Diagnostik noch nicht ausreichend erforscht. Diesbez{\"u}glicher Erkenntnisgewinn wird in der Forschung gegenw{\"a}rtig durch ressourcenintensive und fehleranf{\"a}llige Methoden zur manuellen oder automatisierten Spindeldetektion ausgebremst. Neuere Detektionsans{\"a}tze, die auf Deep-Learning-Verfahren basieren, k{\"o}nnten die Schwierigkeiten bisheriger Detektionsmethoden {\"u}berwinden und damit neue M{\"o}glichkeiten f{\"u}r die praktisch},
  language  = {de}
}
@incollection{LeichtScholtenSteuerDankert2020,
  author    = {Leicht-Scholten, Carmen and Steuer-Dankert, Linda},
  title     = {Educating engineers for socially responsible solutions through design thinking},
  series = {Design thinking in higher education: interdisciplinary encounters},
  booktitle = {Design thinking in higher education: interdisciplinary encounters},
  publisher = {Springer},
  address   = {Singapore},
  isbn      = {978-981-15-5780-4},
  doi       = {10.1007/978-981-15-5780-4},
  pages     = {229 -- 246},
  year      = {2020},
  abstract  = {There is a broad international discussion about rethinking engineering education in order to educate engineers to cope with future challenges, and particularly the sustainable development goals. In this context, there is a consensus about the need to shift from a mostly technical paradigm to a more holistic problem-based approach, which can address the social embeddedness of technology in society. Among the strategies suggested to address this social embeddedness, design thinking has been proposed as an essential complement to engineering precisely for this purpose. This chapter describes the requirements for integrating the design thinking approach in engineering education. We exemplify the requirements and challenges by presenting our approach based on our course experiences at RWTH Aachen University. The chapter first describes the development of our approach of integrating design thinking in engineering curricula, how we combine it with the Sustainable Development Goals (SDG) as well as the role of sustainability and social responsibility in engineering. Secondly, we present the course "Expanding Engineering Limits: Culture, Diversity, and Gender" at RWTH Aachen University. We describe the necessity to theoretically embed the method in social and cultural context, giving students the opportunity to reflect on cultural, national, or individual "engineering limits," and to be able to overcome them using design thinking as a next step for collaborative project work. The paper will suggest that the successful implementation of design thinking as a method in engineering education needs to be framed and contextualized within Science and Technology Studies (STS).},
  language  = {en}
}
@incollection{BraunerVervierBrillowskietal.2022,
  author    = {Brauner, Philipp and Vervier, Luisa and Brillowski, Florian and Dammers, Hannah and Steuer-Dankert, Linda and Schneider, Sebastian and Baier, Ralph and Ziefle, Martina and Gries, Thomas and Leicht-Scholten, Carmen and Mertens, Alexander and Nagel, Saskia K.},
  title     = {Organization Routines in Next Generation Manufacturing},
  series = {Forecasting Next Generation Manufacturing},
  booktitle = {Forecasting Next Generation Manufacturing},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-031-07734-0},
  doi       = {10.1007/978-3-031-07734-0_5},
  pages     = {75 -- 94},
  year      = {2022},
  abstract  = {Next Generation Manufacturing promises significant improvements in performance, productivity, and value creation. In addition to the desired and projected improvements regarding the planning, production, and usage cycles of products, this digital transformation will have a huge impact on work, workers, and workplace design. Given the high uncertainty in the likelihood of occurrence and the technical, economic, and societal impacts of these changes, we conducted a technology foresight study, in the form of a real-time Delphi analysis, to derive reliable future scenarios featuring the next generation of manufacturing systems. This chapter presents the organization dimension and describes each projection in detail, offering current case study examples and discussing related research, as well as implications for policy makers and firms. Specifically, we highlight seven areas in which the digital transformation of production will change how we work, how we organize the work within a company, how we evaluate these changes, and how employment and labor rights will be affected across company boundaries. The experts are unsure whether the use of collaborative robots in factories will replace traditional robots by 2030. They believe that the use of hybrid intelligence will supplement human decision-making processes in production environments. Furthermore, they predict that artificial intelligence will lead to changes in management processes, leadership, and the elimination of hierarchies. However, to ensure that social and normative aspects are incorporated into the AI algorithms, restricting measurement of individual performance will be necessary. Additionally, AI-based decision support can significantly contribute toward new, socially accepted modes of leadership. Finally, the experts believe that there will be a reduction in the workforce by the year 2030.},
  language  = {en}
}
@incollection{HinkeVervierBrauneretal.2022,
  author    = {Hinke, Christian and Vervier, Luisa and Brauner, Philipp and Schneider, Sebastian and Steuer-Dankert, Linda and Ziefle, Martina and Leicht-Scholten, Carmen},
  title     = {Capability configuration in next generation manufacturing},
  series = {Forecasting next generation manufacturing : digital shadows, human-machine collaboration, and data-driven business models},
  booktitle = {Forecasting next generation manufacturing : digital shadows, human-machine collaboration, and data-driven business models},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-031-07733-3},
  doi       = {10.1007/978-3-031-07734-0_6},
  pages     = {95 -- 106},
  year      = {2022},
  abstract  = {Industrial production systems are facing radical change in multiple dimensions. This change is caused by technological developments and the digital transformation of production, as well as the call for political and social change to facilitate a transformation toward sustainability. These changes affect both the capabilities of production systems and companies and the design of higher education and educational programs. Given the high uncertainty in the likelihood of occurrence and the technical, economic, and societal impacts of these concepts, we conducted a technology foresight study, in the form of a real-time Delphi analysis, to derive reliable future scenarios featuring the next generation of manufacturing systems. This chapter presents the capabilities dimension and describes each projection in detail, offering current case study examples and discussing related research, as well as implications for policy makers and firms. Specifically, we discuss the benefits of capturing expert knowledge and making it accessible to newcomers, especially in highly specialized industries. The experts argue that in order to cope with the challenges and circumstances of today's world, students must already during their education at university learn how to work with AI and other technologies. This means that study programs must change and that universities must adapt their structural aspects to meet the needs of the students.},
  language  = {en}
}