@article{AlKaidyDuweHusteretal.2015, author = {Al-Kaidy, Huschyar and Duwe, Anna and Huster, Manuel and Muffler, Kai and Schlegel, Christin and Tim, Sieker and Stadtm{\"u}ller, Ralf and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Biotechnology and bioprocess engineering - from the first ullmann's article to recent trends}, series = {ChemBioEng Reviews}, volume = {2}, journal = {ChemBioEng Reviews}, number = {3}, publisher = {Wiley}, address = {Weinheim}, doi = {10.1002/cben.201500008}, pages = {175 -- 184}, year = {2015}, abstract = {For several thousand years, biotechnology and its associated technical processes have had a great impact on the development of mankind. Based on empirical methods, in particular for the production of foodstuffs and daily commodities, these disciplines have become one of the most innovative future issues. Due to the increasing detailed understanding of cellular processes, production strains can now be optimized. In combination with modern bioprocesses, a variety of bulk and fine chemicals as well as pharmaceuticals can be produced efficiently. In this article, some of the current trends in biotechnology are discussed.}, language = {en} } @article{AlexopoulosHoffschmidt2017, author = {Alexopoulos, Spiros and Hoffschmidt, Bernhard}, title = {Advances in solar tower technology}, series = {Wiley interdisciplinary reviews : Energy and Environment : WIREs}, volume = {6}, journal = {Wiley interdisciplinary reviews : Energy and Environment : WIREs}, number = {1}, publisher = {Wiley}, address = {Weinheim}, issn = {2041-840X}, doi = {10.1002/wene.217}, pages = {1 -- 19}, year = {2017}, language = {en} } @article{AlexyukBogoyavlenskiyAlexyuketal.2021, author = {Alexyuk, Madina and Bogoyavlenskiy, Andrey and Alexyuk, Pavel and Moldakhanov, Yergali and Berezin, Vladimir and Digel, Ilya}, title = {Epipelagic microbiome of the Small Aral Sea: Metagenomic structure and ecological diversity}, series = {MicrobiologyOpen}, volume = {10}, journal = {MicrobiologyOpen}, number = {1}, publisher = {Wiley}, address = {Weinheim}, issn = {2045-8827}, doi = {10.1002/mbo3.1142}, pages = {1 -- 10}, year = {2021}, abstract = {Microbial diversity studies regarding the aquatic communities that experienced or are experiencing environmental problems are essential for the comprehension of the remediation dynamics. In this pilot study, we present data on the phylogenetic and ecological structure of microorganisms from epipelagic water samples collected in the Small Aral Sea (SAS). The raw data were generated by massive parallel sequencing using the shotgun approach. As expected, most of the identified DNA sequences belonged to Terrabacteria and Actinobacteria (40\% and 37\% of the total reads, respectively). The occurrence of Deinococcus-Thermus, Armatimonadetes, Chloroflexi in the epipelagic SAS waters was less anticipated. Surprising was also the detection of sequences, which are characteristic for strict anaerobes—Ignavibacteria, hydrogen-oxidizing bacteria, and archaeal methanogenic species. We suppose that the observed very broad range of phylogenetic and ecological features displayed by the SAS reads demonstrates a more intensive mixing of water masses originating from diverse ecological niches of the Aral-Syr Darya River basin than presumed before.}, language = {en} } @article{AngermannGuenthnerHanssenetal.2022, author = {Angermann, Susanne and G{\"u}nthner, Roman and Hanssen, Henner and Lorenz, Georg and Braunisch, Matthias C. and Steubl, Dominik and Matschkal, Julia and Kemmner, Stephan and Hausinger, Renate and Block, Zenonas and Haller, Bernhard and Heemann, Uwe and Kotliar, Konstantin and Grimmer, Timo and Schmaderer, Christoph}, title = {Cognitive impairment and microvascular function in end-stage renal disease}, series = {International Journal of Methods in Psychiatric Research (MPR)}, volume = {31}, journal = {International Journal of Methods in Psychiatric Research (MPR)}, number = {2}, publisher = {Wiley}, issn = {1049-8931 (Print)}, doi = {10.1002/mpr.1909}, pages = {1 -- 10}, year = {2022}, abstract = {Objective Hemodialysis patients show an approximately threefold higher prevalence of cognitive impairment compared to the age-matched general population. Impaired microcirculatory function is one of the assumed causes. Dynamic retinal vessel analysis is a quantitative method for measuring neurovascular coupling and microvascular endothelial function. We hypothesize that cognitive impairment is associated with altered microcirculation of retinal vessels. Methods 152 chronic hemodialysis patients underwent cognitive testing using the Montreal Cognitive Assessment. Retinal microcirculation was assessed by Dynamic Retinal Vessel Analysis, which carries out an examination recording retinal vessels' reaction to a flicker light stimulus under standardized conditions. Results In unadjusted as well as in adjusted linear regression analyses a significant association between the visuospatial executive function domain score of the Montreal Cognitive Assessment and the maximum arteriolar dilation as response of retinal arterioles to the flicker light stimulation was obtained. Conclusion This is the first study determining retinal microvascular function as surrogate for cerebral microvascular function and cognition in hemodialysis patients. The relationship between impairment in executive function and reduced arteriolar reaction to flicker light stimulation supports the involvement of cerebral small vessel disease as contributing factor for the development of cognitive impairment in this patient population and might be a target for noninvasive disease monitoring and therapeutic intervention.}, language = {en} } @article{AridaTurekRolkaetal.2009, author = {Arida, Hassan and Turek, Monika and Rolka, David and Sch{\"o}ning, Michael Josef}, title = {A Novel Thin-Film Copper Array Based on an Organic/Inorganic Sensor Hybrid: Microfabrication, Potentiometric Characterization, and Flow-Injection Analysis Application}, series = {Electroanalysis. 21 (2009), H. 10}, journal = {Electroanalysis. 21 (2009), H. 10}, publisher = {Wiley}, address = {Weinheim}, isbn = {1040-0397}, pages = {1145 -- 1151}, year = {2009}, language = {en} } @article{BankOrzadaSmitsetal.2015, author = {Bank, Bart L. van de and Orzada, Stephan and Smits, Frits and Lagemaat, Miriam W. and Rodgers, Christopher T. and Bitz, Andreas and Scheenen, Tom W. J.}, title = {Optimized (31) P MRS in the human brain at 7 T with a dedicated RF coil setup}, series = {NMR in Biomedicine}, volume = {28}, journal = {NMR in Biomedicine}, number = {11}, publisher = {Wiley}, address = {Weinheim}, issn = {1099-1492}, doi = {10.1002/nbm.3422}, pages = {1570 -- 1578}, year = {2015}, language = {en} } @article{BegingLeinhosJablonskietal.2015, author = {Beging, Stefan and Leinhos, Marcel and Jablonski, Melanie and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Studying the spatially resolved immobilisation of enzymes on a capacitive field-effect structure by means of nano-spotting}, series = {Physica status solidi (a)}, volume = {212}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201431891}, pages = {1353 -- 1358}, year = {2015}, language = {en} } @article{BlankeRegerDoeringetal.2021, author = {Blanke, Tobias and Reger, Vitali and D{\"o}ring, Bernd and G{\"o}ttsche, Joachim and Kuhnhenne, Markus}, title = {Koaxiale Stahlenergiepf{\"a}hle}, series = {Stahlbau}, volume = {90. 2021}, journal = {Stahlbau}, number = {6}, publisher = {Wiley}, address = {Weinheim}, pages = {417 -- 424}, year = {2021}, abstract = {Ein entscheidender Teil der Energiewende ist die W{\"a}rmewende im Geb{\"a}udesektor. Ein Schl{\"u}sselelement sind hier W{\"a}rmepumpen. Diese ben{\"o}tigen eine W{\"a}rmequelle, der sie Energie entziehen k{\"o}nnen, um sie auf ein h{\"o}heres Temperaturniveau zu transformieren. Diese W{\"a}rmequelle kann bspw. das Erdreich sein, dessen W{\"a}rme durch Erdsonden erschlossen werden kann. In diesem Beitrag werden in Stahlpf{\"a}hle integrierte Koaxialsonden mit dem Stand der Technik von Erdsonden gleichen Durchmessers bez{\"u}glich ihrer thermischen Leistungsmerkmale verglichen. Die Stahlenergiepf{\"a}hle bieten neben der W{\"a}rmegewinnung weitere Vorteile, da sie auch eine statische Funktion {\"u}bernehmen und r{\"u}ckstandsfrei zur{\"u}ckgebaut werden k{\"o}nnen. Es werden analytische und numerische Berechnungen vorgestellt, um die thermischen Potenziale beider Systeme zu vergleichen. Außerdem wird ein Testaufbau gezeigt, bei dem Stahlenergiepf{\"a}hle in zwei verschiedenen L{\"a}ngen mit vorhandenen g{\"a}ngigen Erdsonden verglichen werden k{\"o}nnen. Die Berechnungen zeigen einen deutlichen thermischen Mehrertrag zwischen 26 \% und 148 \% der Stahlenergiepf{\"a}hle gegen{\"u}ber dem Stand der Technik abh{\"a}ngig vom Erdreich. Die Messergebnisse zeigen einen thermischen Mehrertrag von {\"u}ber 100 \%. Es l{\"a}sst sich also signifikante Erdsondenl{\"a}nge einsparen. Dabei ist zu beachten, dass sich damit der thermisch genutzte Bereich des Erdreichs reduziert, wodurch die thermische Regeneration und/oder das Langzeitverhalten des Erdreichs an Bedeutung gewinnt.}, language = {de} } @article{BohrnStuetzFleischeretal.2011, author = {Bohrn, Ulrich and St{\"u}tz, Evamaria and Fleischer, Maximilian and Sch{\"o}ning, Michael Josef and Wagner, Patrick}, title = {Eukaryotic cell lines as a sensitive layer for direct monitoring of carbon monoxide}, series = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6}, journal = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6}, publisher = {Wiley}, address = {Weinheim}, isbn = {1862-6319}, pages = {1345 -- 1350}, year = {2011}, language = {en} } @article{BongaertsEsserLorbachetal.2011, author = {Bongaerts, Johannes and Esser, Simon and Lorbach, Volker and Al-Momani, L{\´o}ay and M{\"u}ller, Michael A. and Franke, Dirk and Grondal, Christoph and Kurutsch, Anja and Bujnicki, Robert and Takors, Ralf and Raeven, Leon and Wubbolts, Marcel and Bovenberg, Roel and Nieger, Martin and Sch{\"u}rmann, Melanie and Trachtmann, Natalie and Kozak, Stefan and Sprenger, Georg A. and M{\"u}ller, Michael}, title = {Diversity-oriented production of metabolites derived from chorismate and their use in organic synthesis}, series = {Angewandte Chemie International Edition}, volume = {Vol. 50}, journal = {Angewandte Chemie International Edition}, number = {Iss. 34}, publisher = {Wiley}, address = {Weinheim}, issn = {1521-3773 (E-Journal); 0570-0833 (Print); 1433-7851 (Print)}, pages = {7781 -- 7786}, year = {2011}, language = {en} } @article{BreuerRaueKirschbaumetal.2015, author = {Breuer, Lars and Raue, Markus and Kirschbaum, M. and Mang, Thomas and Sch{\"o}ning, Michael Josef and Thoelen, R. and Wagner, Torsten}, title = {Light-controllable polymeric material based on temperature-sensitive hydrogels with incorporated graphene oxide}, series = {Physica status solidi (a)}, volume = {212}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201431944}, pages = {1368 -- 1374}, year = {2015}, abstract = {Poly(N-isopropylacrylamide) (PNIPAAm) hydrogel films with incorporated graphene oxide (GO) were developed and tested as light-stimulated actuators. GO dispersions were synthesized via Hummers method and characterized toward their optical properties and photothermal energy conversion. The hydrogels were prepared by means of photopolymerization. In addition, the influence of GO within the hydrogel network on the lower critical solution temperature (LCST) was investigated by differential scanning calorimetry (DSC). The optical absorbance and the response to illumination were determined as a function of GO concentration for thin hydrogel films. A proof of principle for the stimulation with light was performed.}, language = {en} } @article{BrockhausBehbahaniMurisetal.2021, author = {Brockhaus, Moritz K. and Behbahani, Mehdi and Muris, Farina and Jansen, Sebastian V. and Schmitz- Rode, Thomas and Steinseifer, Ulrich and Clauser, Johanna C.}, title = {In vitro thrombogenicity testing of pulsatile mechanical circulatory support systems: Design and proof-of-concept}, series = {Artificial Organs}, volume = {45}, journal = {Artificial Organs}, number = {12}, publisher = {Wiley}, address = {Weinheim}, issn = {1525-1594}, doi = {10.1111/aor.14046}, pages = {1513 -- 1521}, year = {2021}, abstract = {Thrombogenic complications are a main issue in mechanical circulatory support (MCS). There is no validated in vitro method available to quantitatively assess the thrombogenic performance of pulsatile MCS devices under realistic hemodynamic conditions. The aim of this study is to propose a method to evaluate the thrombogenic potential of new designs without the use of complex in-vivo trials. This study presents a novel in vitro method for reproducible thrombogenicity testing of pulsatile MCS systems using low molecular weight heparinized porcine blood. Blood parameters are continuously measured with full blood thromboelastometry (ROTEM; EXTEM, FIBTEM and a custom-made analysis HEPNATEM). Thrombus formation is optically observed after four hours of testing. The results of three experiments are presented each with two parallel loops. The area of thrombus formation inside the MCS device was reproducible. The implantation of a filter inside the loop catches embolizing thrombi without a measurable increase of platelet activation, allowing conclusions of the place of origin of thrombi inside the device. EXTEM and FIBTEM parameters such as clotting velocity (α) and maximum clot firmness (MCF) show a total decrease by around 6\% with a characteristic kink after 180 minutes. HEPNATEM α and MCF rise within the first 180 minutes indicate a continuously increasing activation level of coagulation. After 180 minutes, the consumption of clotting factors prevails, resulting in a decrease of α and MCF. With the designed mock loop and the presented protocol we are able to identify thrombogenic hot spots inside a pulsatile pump and characterize their thrombogenic potential.}, language = {en} } @article{ButenwegFehling2012, author = {Butenweg, Christoph and Fehling, Ekkehard}, title = {Hintergrund f{\"u}r die vereinfachten Regeln bei Mauerwerksgeb{\"a}uden im Erdbebenfall}, series = {Mauerwerk : European journal of masonry}, volume = {Volume 16}, journal = {Mauerwerk : European journal of masonry}, number = {Issue 3}, publisher = {Wiley}, address = {Weinheim}, issn = {1437-1022 (E-Journal); 1432-3427 (Print)}, doi = {10.1002/dama.201200537}, pages = {127 -- 137}, year = {2012}, abstract = {Bei der Ausarbeitung des nationalen Anwendungsdokumentes zur DIN EN 1998-1 waren die in der ENV-Fassung enthaltenen vereinfachten Regeln im Lichte aktueller Forschungsergebnisse zu {\"u}berpr{\"u}fen und zu {\"u}berarbeiten. Die gleiche Aufgabe stellte sich auch f{\"u}r die Neufassung der DIN 4149. In beiden F{\"a}llen sind neben konstruktiven Regeln f{\"u}r die Art und Anordnung der zur Geb{\"a}udeaussteifung heranzuziehenden W{\"a}nde im Grundriss Tabellen enthalten, die unter bestimmten Bedingungen den Entfall eines rechnerischen Nachweises der Tragw{\"a}nde im Erdbebenfall erm{\"o}glichen. Dies ist f{\"u}r Schwachbebengebiete, wie sie in Deutschland und anderen L{\"a}ndern Mitteleuropas anzutreffen sind, sinnvoll, um unn{\"o}tigen Rechenaufwand sowie Probleme mit der F{\"u}hrbarkeit von Nachweisen so weit wie m{\"o}glich auszuschalten. Im vorliegenden Beitrag werden die Hintergr{\"u}nde der vereinfachten Regeln diskutiert und die Ergebnisse der Anwendung mit verschiedenen Rechenverfahren verglichen und bewertet.}, language = {de} } @article{ButenwegGellert2012, author = {Butenweg, Christoph and Gellert, Christoph}, title = {Integrale Geb{\"a}udeplanung am Beispiel eines Geschossbaus in Ziegelmauerwerk}, series = {Mauerwerk : European journal of masonry}, volume = {Volume 16}, journal = {Mauerwerk : European journal of masonry}, number = {5}, publisher = {Wiley}, address = {Weinheim}, issn = {1437-1022 (E-Journal); 1432-3427 (Print)}, doi = {10.1002/dama.201200550}, pages = {247 -- 254}, year = {2012}, abstract = {Moderne Mauerwerksbauten m{\"u}ssen nach heutigen Anforderungen architektonisch, statisch, energetisch sowie schall- und brandschutztechnisch optimal ausgelegt sein. Aufgrund der Komplexit{\"a}t und engen Verzahnung der einzelnen Anforderungen ist eine integrale Geb{\"a}udeplanung zur Erzielung einer qualitativ hochwertigen Bauwerksl{\"o}sung unbedingt notwendig. Diese erfordert von den Fachplanern vertieftes Spezialwissen in den verschiedenen Bereichen, um insbesondere die Schnittstellen und Bauwerksdetails korrekt zu planen und auszuf{\"u}hren. Der Beitrag stellt die integrale Geb{\"a}udeplanung am Beispiel eines Geschossbaus in Ziegelbauweise mit L{\"o}sungen f{\"u}r wesentliche Detailpunkte vor}, language = {de} } @article{ButenwegGellert2013, author = {Butenweg, Christoph and Gellert, Christoph}, title = {Nichtlinearer Nachweis von Mauerwerksbauten}, series = {Mauerwerk : European journal of masonry}, volume = {Volume 17}, journal = {Mauerwerk : European journal of masonry}, number = {Issue 3}, publisher = {Wiley}, address = {Weinheim}, issn = {1437-1022 (E-Journal); 1432-3427 (Print)}, doi = {10.1002/dama.201300575}, pages = {166 -- 171}, year = {2013}, language = {de} } @article{ButenwegRosin2020, author = {Butenweg, Christoph and Rosin, Julia}, title = {Seismischer Nachweis von Mauerwerksbauten in deutschen Erdbebengebieten}, series = {Mauerwerk}, volume = {24}, journal = {Mauerwerk}, number = {2}, publisher = {Wiley}, address = {Weinheim}, issn = {1437-1022}, doi = {10.1002/dama.202000006}, pages = {108 -- 113}, year = {2020}, abstract = {Mit finanzieller Unterst{\"u}tzung der Deutschen Gesellschaft f{\"u}r Mauerwerks- und Wohnungsbau e.V. (DGfM) und des Deutschen Instituts f{\"u}r Bautechnik in Berlin (DIBt) wurden zwei aufeinander aufbauende Forschungsvorhaben zur Verbesserung der seismischen Nachweise von Mauerwerksbauten in deutschen Erdbebengebieten durchgef{\"u}hrt. Zun{\"a}chst wurde das seismische Verhalten von drei modernen unbewehrten Mauerwerksgeb{\"a}uden in der Region Emilia Romagna in Italien w{\"a}hrend der Erdbebenserie im Jahr 2012 in Kooperation mit der Universit{\"a}t Pavia eingehend untersucht. Aufbauend auf den Erkenntnissen dieser Untersuchungen wurde ein verbessertes seismisches Bemessungskonzept f{\"u}r unbewehrte Mauerwerksbauten erarbeitet. Der Beitrag stellt die wesentlichen Ergebnisse dieser Forschungsarbeiten und deren Eingang in die Normung vor.}, language = {de} } @article{BaeckerPouyeshmanSchnitzleretal.2011, author = {B{\"a}cker, Matthias and Pouyeshman, S. and Schnitzler, Thomas and Poghossian, Arshak and Wagner, Patrick and Biselli, Manfred and Sch{\"o}ning, Michael Josef}, title = {A silicon-based multi-sensor chip for monitoring of fermentation processes}, series = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6}, journal = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6}, publisher = {Wiley}, address = {Weinheim}, isbn = {1862-6319}, pages = {1364 -- 1369}, year = {2011}, language = {en} } @article{BaeckerSchusserPoghossianetal.2014, author = {B{\"a}cker, Matthias and Schusser, Sebastian and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Multi-Parametererfassung mit siliziumbasiertem Sensorchip: Aus Drei mach Eins}, series = {GIT Labor-Fachzeitschrift}, journal = {GIT Labor-Fachzeitschrift}, number = {2}, publisher = {Wiley}, issn = {0016-3538}, pages = {28 -- 30}, year = {2014}, language = {de} } @article{CampenKowalskiLyonsetal.2019, author = {Campen, R. and Kowalski, Julia and Lyons, W.B. and Tulaczyk, S. and Dachwald, Bernd and Pettit, E. and Welch, K. A. and Mikucki, J.A.}, title = {Microbial diversity of an Antarctic subglacial community and high-resolution replicate sampling inform hydrological connectivity in a polar desert}, series = {Environmental Microbiology}, journal = {Environmental Microbiology}, number = {accepted article}, publisher = {Wiley}, address = {Weinheim}, issn = {1462-2920}, doi = {10.1111/1462-2920.14607}, year = {2019}, language = {en} } @article{CheenakulaPaulsenOttetal.2023, author = {Cheenakula, Dheeraja and Paulsen, Svea and Ott, Fabian and Gr{\"o}mping, Markus}, title = {Operational window of a deammonifying sludge for mainstream application in a municipal wastewater treatment plant}, series = {Water and Environment Journal}, volume = {38}, journal = {Water and Environment Journal}, number = {1}, publisher = {Wiley}, address = {Chichester}, issn = {1747-6593}, doi = {10.1111/wej.12898}, pages = {59 -- 70}, year = {2023}, abstract = {The present work aimed to study the mainstream feasibility of the deammonifying sludge of side stream of municipal wastewater treatment plant (MWWTP) in Kaster, Germany. For this purpose, the deammonifying sludge available at the side stream was investigated for nitrogen (N) removal with respect to the operational factors temperature (15-30°C), pH value (6.0-8.0) and chemical oxygen demand (COD)/N ratio (≤1.5-6.0). The highest and lowest N-removal rates of 0.13 and 0.045 kg/(m³ d) are achieved at 30 and 15°C, respectively. Different conditions of pH and COD/N ratios in the SBRs of Partial nitritation/anammox (PN/A) significantly influenced both the metabolic processes and associated N-removal rates. The scientific insights gained from the current work signifies the possibility of mainstream PN/A at WWTPs. The current study forms a solid basis of operational window for the upcoming semi-technical trails to be conducted prior to the full-scale mainstream PN/A at WWTP Kaster and WWTPs globally.}, language = {en} }