@incollection{ReimerBraunWellmeretal.2010, author = {Reimer, Lars and Braun, Carsten and Wellmer, Georg and Behr, Marek and Ballmann, Josef}, title = {Development of a modular method for computational aero-structural analysis of aircraft}, series = {Summary of flow modulation and fluid-structure interaction findings. Results of the Collaborative Research Center SFB 401 at the RWTH Aachen University, Aachen, Germany, 1997-2008 / ed.: Wolfgang Schr{\"o}der. Notes on numerical fluid mechanics and multidisciplinary design. Vol. 109}, booktitle = {Summary of flow modulation and fluid-structure interaction findings. Results of the Collaborative Research Center SFB 401 at the RWTH Aachen University, Aachen, Germany, 1997-2008 / ed.: Wolfgang Schr{\"o}der. Notes on numerical fluid mechanics and multidisciplinary design. Vol. 109}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-642-04087-0}, pages = {205 -- 238}, year = {2010}, language = {en} } @incollection{BrittenBraunHesseetal.2003, author = {Britten, G. and Braun, Carsten and Hesse, M. and Ballmann, Josef}, title = {Computational aeroelasticity with reduced structural models}, series = {Flow modulation and fluid-structure interaction at airplane wings : research results of the Collaborative Research Center SFB 401 at RWTH Aachen, University of Technology, Aachen, Germany / Josef Ballmann (Ed.) Notes on numerical fluid mechanics and multidisciplinary design. Vol. 84}, booktitle = {Flow modulation and fluid-structure interaction at airplane wings : research results of the Collaborative Research Center SFB 401 at RWTH Aachen, University of Technology, Aachen, Germany / Josef Ballmann (Ed.) Notes on numerical fluid mechanics and multidisciplinary design. Vol. 84}, publisher = {Springer}, address = {Berlin}, isbn = {3-540-40209-8}, pages = {275 -- 299}, year = {2003}, language = {en} } @incollection{EngelmannBaumann2022, author = {Engelmann, Ulrich M. and Baumann, Martin}, title = {Moderationsexpertise f{\"u}r QMBs - das Mindset}, series = {Qualit{\"a}tsmanagement im Gesundheitswesen}, booktitle = {Qualit{\"a}tsmanagement im Gesundheitswesen}, editor = {Herbig, Nicola and Poppelreuter, Stefan}, edition = {59. Update}, publisher = {T{\"U}V-Verlag}, address = {K{\"o}ln}, isbn = {978-3-8249-0714-4}, pages = {Kapitel 10814}, year = {2022}, abstract = {Teamsitzungen, Arbeitsgruppentreffen, Kickoffs und Meetings - sie alle werden mit dem Ziel durchgef{\"u}hrt, innerhalb einer vorgegebenen Zeitspanne ein gemeinsames Arbeitsziel zu erreichen. Damit die Zielerreichung auch bei komplexeren Arbeitsauftr{\"a}gen nicht vom Zufall abh{\"a}ngt, empfiehlt es sich, die Leitung des Ablaufs einem Moderator zu {\"u}bertragen. In diesem Beitrag einer mehrteiligen Serie wird beschrieben, {\"u}ber welches Mindset der Moderator verf{\"u}gen sollte, welche grunds{\"a}tzlichen Methoden hilfreich sind und was bei der Onlinemoderation im Besonderen zu beachten ist.}, language = {de} } @incollection{ButenwegKlinkel2014, author = {Butenweg, Christoph and Klinkel, Sven}, title = {Dynamisches Verhalten von Stahlbetonplatten unter Impact-Belastungen}, series = {Massivbau im Wandel : Festschrift zum 60. Geburtstag von Josef Hegger}, booktitle = {Massivbau im Wandel : Festschrift zum 60. Geburtstag von Josef Hegger}, publisher = {Ernst}, address = {Berlin}, isbn = {3-939051-20-9}, pages = {369 -- 380}, year = {2014}, language = {de} } @incollection{MeskourisGellertButenweg2010, author = {Meskouris, Konstantin and Gellert, Christoph and Butenweg, Christoph}, title = {Neuer Ansatz f{\"u}r die Bemessung von Mauerwerksbauten}, series = {Innovationen im konstruktiven Ingenieurbau : Methoden - Materialien - Bauwerke ; Festschrift Professor Hirschfeld / hrsg. von Karl Beucke}, booktitle = {Innovationen im konstruktiven Ingenieurbau : Methoden - Materialien - Bauwerke ; Festschrift Professor Hirschfeld / hrsg. von Karl Beucke}, publisher = {Bauhaus-Univ. Weimar}, address = {Weimar}, pages = {217 -- 224}, year = {2010}, language = {de} } @incollection{AltayTaddeiButenwegetal.2014, author = {Altay, Okyay and Taddei, Francesca and Butenweg, Christoph and Klinkel, Sven}, title = {Vibration mitigation of wind turbine towers with tuned mass dampers}, series = {Wind turbine control and monitoring. (Advances in industrial control)}, booktitle = {Wind turbine control and monitoring. (Advances in industrial control)}, publisher = {Springer}, address = {Cham ; Heidelberg ; New York ; Dordrecht ; London}, isbn = {978-3-319-08412-1 (Print) ; 978-3-319-08413-8 (E-Book)}, doi = {10.1007/978-3-319-08413-8_12}, pages = {337 -- 373}, year = {2014}, abstract = {Because of its minor environmental impact, electricity generation using wind power is getting remarkable. The further growth of the wind industry depends on technological solutions to the challenges in production and construction of the turbines. Wind turbine tower vibrations, which limit power generation efficiency and cause fatigue problems with high maintenance costs, count as one of the main structural difficulties in the wind energy sector. To mitigate tower vibrations auxiliary measures are necessary. The effectiveness of tuned mass damper is verified by means of a numeric study on a 5 MW onshore reference wind turbine. Hereby, also seismic-induced vibrations and soil-structure interaction are considered. Acquired results show that tuned mass damper can effectively reduce resonant tower vibrations and improve the fatigue life of wind turbines. This chapter is also concerned with tuned liquid column damper and a semiactive application of it. Due to its geometric versatility and low prime costs, tuned liquid column dampers are a good alternative to other damping measures, in particular for slender structures like wind turbines.}, language = {en} } @incollection{ButenwegNorda2014, author = {Butenweg, Christoph and Norda, H.}, title = {Erdbebenberechnung von Mauerwerksbauten nach DIN EN 1998-1:2010-12}, series = {Mauerwerksbau-Praxis nach Eurocode / Schubert, Schneider, Schoch (Hrsg.). - 3., vollst{\"a}ndig {\"u}berarbeitete Auflage}, booktitle = {Mauerwerksbau-Praxis nach Eurocode / Schubert, Schneider, Schoch (Hrsg.). - 3., vollst{\"a}ndig {\"u}berarbeitete Auflage}, publisher = {Beuth}, address = {Berlin, Wien, Z{\"u}rich}, isbn = {978-3-410-22739-7}, pages = {367 -- 412}, year = {2014}, language = {de} } @incollection{Eggert2019, author = {Eggert, Mathias}, title = {Big Data Research - How to Structure the Changes of the Past Decade?}, series = {The Art of Structuring}, booktitle = {The Art of Structuring}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-06234-7}, doi = {10.1007/978-3-030-06234-7_26}, pages = {271 -- 281}, year = {2019}, abstract = {In the past decade, many IS researchers focused on researching the phenomenon of Big Data. At the same time, the relevance of data protection gets more attention than ever before. In particular, since the enactment of the European General Data Protection Regulation in May 2018 Information Systems research should provide answers for protecting personal data. The article at hand presents a structuring framework for Big Data research outcome and the consideration of data protection. IS Researchers might use the framework in order to structure Big Data literature and to identify research gaps that should be addressed in the future.}, language = {en} } @incollection{KuhlmannButenwegMeskourisetal.2012, author = {Kuhlmann, Wolfram and Butenweg, Christoph and Meskouris, Konstantin and Kempen, Thomas}, title = {Simulation des Tragverhaltens des Aachener Doms im Erdbebenfall}, series = {Die karolingische Pfalzkapelle in Aachen : Material, Bautechnik, Restaurierung. (Arbeitshefte der rheinischen Denkmalpflege ; 78)}, booktitle = {Die karolingische Pfalzkapelle in Aachen : Material, Bautechnik, Restaurierung. (Arbeitshefte der rheinischen Denkmalpflege ; 78)}, publisher = {Wernersche Verlags-Gesellschaft}, address = {Worms}, isbn = {978-3-88462-325-1}, pages = {237 -- 248}, year = {2012}, language = {de} } @incollection{ButenwegRoeser2016, author = {Butenweg, Christoph and Roeser, W.}, title = {Auslegung von Bauwerken gegen Erdbeben - Rechenbeispiele}, series = {Stahlbetonbau aktuell 2016 : Praxishandbuch / herausgegeben von: Prof. Dr.-Ing. Josef Hegger, Prof. Dr.-Ing. habil. Peter Mark}, booktitle = {Stahlbetonbau aktuell 2016 : Praxishandbuch / herausgegeben von: Prof. Dr.-Ing. Josef Hegger, Prof. Dr.-Ing. habil. Peter Mark}, publisher = {Beuth Verlag GmbH}, address = {Berlin ; Wien ; Z{\"u}rich}, isbn = {978-3-410-25202-3 (Print) ; 978-3-410-25203-0 (E-Book)}, year = {2016}, language = {de} } @incollection{ButenwegGellertMeyer2010, author = {Butenweg, Christoph and Gellert, Christoph and Meyer, Udo}, title = {Erdbebenbemessung bei Mauerwerksbauten}, series = {Mauerwerk-Kalender 2010: Normen f{\"u}r Bemessung und Ausf{\"u}hrung}, booktitle = {Mauerwerk-Kalender 2010: Normen f{\"u}r Bemessung und Ausf{\"u}hrung}, publisher = {Ernst \& Sohn}, address = {Berlin}, isbn = {3-433-60040-6 ; 978-3-433-60040-5}, doi = {10.1002/9783433600405.ch7}, pages = {141 -- 167}, year = {2010}, language = {de} } @incollection{ButenwegRoeser2012, author = {Butenweg, Christoph and Roeser, W.}, title = {Erdbebenbemessung von Stahlbetontragwerken nach DIN EN 1998-1}, series = {Stahlbetonbau aktuell : Praxishandbuch}, booktitle = {Stahlbetonbau aktuell : Praxishandbuch}, publisher = {Beuth}, address = {Berlin}, isbn = {978-3-410-21932-3 (Print) ; 978-341-02193-3-0 (E-Book)}, pages = {A.1 -- A.43}, year = {2012}, language = {de} } @incollection{ButenwegGellertMeyer2021, author = {Butenweg, Christoph and Gellert, Christoph and Meyer, Udo}, title = {Erdbebenbemessung bei Mauerwerksbauten}, series = {Mauerwerk Kalender 2021: Kunststoffverankerungen Digitalisierung im Mauerwerksbau}, booktitle = {Mauerwerk Kalender 2021: Kunststoffverankerungen Digitalisierung im Mauerwerksbau}, publisher = {Ernst \& Sohn}, address = {Berlin}, isbn = {9783433032930}, doi = {10.1002/9783433610732.ch12}, pages = {329 -- 355}, year = {2021}, abstract = {Der vorliegende Beitrag stellt den seismischen Nachweis von Mauerwerksbauten in Deutschland auf Grundlage der DIN EN 1998-1/NA vor, wobei auch die wesentlichen {\"A}nderungen zu der Norm DIN 4149 vergleichend erl{\"a}utert werden. Vorgestellt werden die Definition der Erdbebeneinwirkung, das seismische Verhalten von Mauerwerksbauten und die Erl{\"a}uterung der Rechenverfahren. Darauf aufbauend wird die Anwendung an drei Praxisbeispielen demonstriert.}, language = {de} } @incollection{Dachwald2017, author = {Dachwald, Bernd}, title = {Light propulsion systems for spacecraft}, series = {Optical nano and micro actuator technology}, booktitle = {Optical nano and micro actuator technology}, editor = {Knopf, George K. and Otani, Yukitoshi}, publisher = {CRC Press}, address = {Boca Raton}, isbn = {9781315217628 (eBook)}, pages = {577 -- 598}, year = {2017}, language = {en} } @incollection{AkimbekovZhanadilovnaUalievaetal.2020, author = {Akimbekov, Nuraly S. and Zhanadilovna, Abdieva G. and Ualieva, Perizat S. and Abaihanovna, Zhusipova D. and Digel, Ilya and Savitskaya, Irina S. and Zhubanova, Azhar Achmet}, title = {Functionalization of Carbon Based Wound Dressings with Antimicrobial Phytoextracts for Bioactive Treatment of Septic Wounds}, series = {Carbon Nanomaterials in Biomedicine and the Environment}, booktitle = {Carbon Nanomaterials in Biomedicine and the Environment}, publisher = {Jenny Stanford Publishing}, address = {Singapore}, isbn = {978-981-4800-27-3}, doi = {10.1201/9780429428647-11}, pages = {211 -- 228}, year = {2020}, abstract = {The treatment of septic wounds with curative dressings based on biocomposites containing sage and marigold phytoextracts was effective in in vitro and in vivo experiments. These dressings caused the purification of the wound surface from purulent-necrotic masses three days earlier than in the other experimental groups. The consequence of an increase in incidents of severe course of the wound and the observed tendency to increase the number of adverse effects is the development of long-term recurrent wound processes. To treat purulent wounds, the following tactics were used: The purulent wounds of animals were covered with the examined wound dressing, and then the next day samples were taken, the procedure was performed once in 2 days. To obtain the active nanostructured sorbents such as carbonized rice husks, they are functionalized with biologically active components possessing antimicrobial, anti-inflammatory, antitoxic, immunomodulating, antiallergic and other types of properties.}, language = {en} } @incollection{SavitskayaKistaubayevaAkimbekovetal.2020, author = {Savitskaya, Irina S. and Kistaubayeva, Aida S. and Akimbekov, Nuraly S. and Digel, Ilya and Shokatayeva, Dina and Zhubanova, Azhar Achmet}, title = {Prospective Use of Probiotics Immobilized on Sorbents with Nanostructured Surfaces}, series = {Carbon Nanomaterials in Biomedicine and the Environment}, booktitle = {Carbon Nanomaterials in Biomedicine and the Environment}, publisher = {Jenny Stanford Publishing}, address = {Singapore}, isbn = {978-981-4800-27-3}, doi = {10.1201/9780429428647-12}, pages = {229 -- 267}, year = {2020}, abstract = {Activated carbons are known as excellent adsorbents. Their applications include the adsorptive removal of color, odor, taste, undesirable organic and inorganic pollutants from drinking and waste water; air purification in inhabited spaces; purification of many chemicals, pharmaceutical products and many others. This chapter elucidates the role of normal microflora in the maintenance of human health and presents materials on possible clinical displays of microecological infringements and ways of their correction. It presents new developments concerning new probiotics with immobilized Lactobacillus and Bacillus. The chapter considers the mechanisms of the intestine disbacteriosis correction by sorbed probiotics. It demonstrates the advantages and creation prospects of immobilized probiotics developed on the basis of carbonized rice husk. There are great prospects for the development of medical biotechnology due to use of carbon sorbents with a nanostructured surface. Microbial communities form a biocenosis of the biotope and together with the host organism create permanent or temporary ecosystems.}, language = {en} } @incollection{DiekmannEggert2021, author = {Diekmann, Julian and Eggert, Mathias}, title = {Is a Progressive Web App an Alternative for Native App Development?}, series = {3. Wissenschaftsforum: Digitale Transformation (WiFo21) (Lecture Notes in Informatics ; P-319)}, booktitle = {3. Wissenschaftsforum: Digitale Transformation (WiFo21) (Lecture Notes in Informatics ; P-319)}, publisher = {Gesellschaft f{\"u}r Informatik}, address = {Darmstadt}, isbn = {978-3-88579-713-5}, pages = {35 -- 48}, year = {2021}, abstract = {The existence of several mobile operating systems, such as Android and iOS, is a challenge for developers because the individual platforms are not compatible with each other and require separate app developments. For this reason, cross-platform approaches have become popular but lack in cloning the native behavior of the different operating systems. Out of the plenty cross-platform approaches, the progressive web app (PWA) approach is perceived as promising but needs further investigation. Therefore, the paper at hand aims at investigating whether PWAs are a suitable alternative for native apps by developing a PWA clone of an existing app. Two surveys are conducted in which potential users test and evaluate the PWA prototype with regard to its usability. The survey results indicate that PWAs have great potential, but cannot be treated as a general alternative to native apps. For guiding developers when and how to use PWAs, four design guidelines for the development of PWA-based apps are derived based on the results.}, language = {en} } @incollection{Dachwald2010, author = {Dachwald, Bernd}, title = {Solar sail dynamics and control}, series = {Encyclopedia of Aerospace Engineering}, booktitle = {Encyclopedia of Aerospace Engineering}, publisher = {Wiley}, address = {Hoboken}, doi = {10.1002/9780470686652.eae292}, year = {2010}, abstract = {Solar sails are large and lightweight reflective structures that are propelled by solar radiation pressure. This chapter covers their orbital and attitude dynamics and control. First, the advantages and limitations of solar sails are discussed and their history and development status is outlined. Because the dynamics of solar sails is governed by the (thermo-)optical properties of the sail film, the basic solar radiation pressure force models have to be described and compared before parameters to measure solar sail performance can be defined. The next part covers the orbital dynamics of solar sails for heliocentric motion, planetocentric motion, and motion at Lagrangian equilibrium points. Afterwards, some advanced solar radiation pressure force models are described, which allow to quantify the thrust force on solar sails of arbitrary shape, the effects of temperature, of light incidence angle, of surface roughness, and the effects of optical degradation of the sail film in the space environment. The orbital motion of a solar sail is strongly coupled to its rotational motion, so that the attitude control of these soft and flexible structures is very challenging, especially for planetocentric orbits that require fast attitude maneuvers. Finally, some potential attitude control methods are sketched and selection criteria are given.}, language = {en} } @incollection{ZhubanovaMansurovDigel2020, author = {Zhubanova, Azhar A. and Mansurov, Zulkhair A. and Digel, Ilya}, title = {Use of Advanced Nanomaterials for Bioremediation of Contaminated Ecosystems}, series = {Carbon Nanomaterials in Biomedicine and the Environment}, booktitle = {Carbon Nanomaterials in Biomedicine and the Environment}, publisher = {Jenny Stanford Publishing}, address = {Singapore}, isbn = {978-981-4800-27-3}, doi = {10.1201/9780429428647-18}, pages = {353 -- 378}, year = {2020}, abstract = {This chapter shows that nanomaterials obtained by high-temperature carbonization of inexpensive plant raw material such as rice husk, grape seeds, and walnut shells can serve as a basis for the production of highly efficient microbial drugs, biodestructors, biosorbents, and biocatalysts, which are promising for the remediation of the ecosystem contaminated with heavy and radioactive metals, oil and oil products. A strong interest in engineering zymology is dictated by the necessity to address the issues of monitoring enzymatic processes, treatment, and diagnosis of a number of common human diseases, environmental pollution, quality control of pharmaceuticals and food. Nanomaterials obtained by high-temperature carbonization of cheap plant raw material such as-rice husks, grape seeds and walnut shells, can serve as a basis for creating of highly effective microbial preparations-biodestructors, biosorbents and biocatalysts, which are promising for the use of contaminated ecosystems, and for restoration of human intestine microecology.}, language = {en} } @incollection{AkimbekovDigelRazzaque2022, author = {Akimbekov, Nuraly S. and Digel, Ilya and Razzaque, Mohammed S.}, title = {Role of vitamins in maintaining structure and function of intestinal microbiome}, series = {Comprehensive Gut Microbiota}, booktitle = {Comprehensive Gut Microbiota}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {978-0-12-822036-8}, doi = {10.1016/B978-0-12-819265-8.00043-7}, pages = {320 -- 334}, year = {2022}, abstract = {The recent advances in microbiology have shed light on understanding the role of vitamins beyond the nutritional range. Vitamins are critical in contributing to healthy biodiversity and maintaining the proper function of gut microbiota. The sharing of vitamins among bacterial populations promotes stability in community composition and diversity; however, this balance becomes disturbed in various pathologies. Here, we overview and analyze the ability of different vitamins to selectively and specifically induce changes in the intestinal microbial community. Some schemes and regularities become visible, which may provide new insights and avenues for therapeutic management and functional optimization of the gut microbiota.}, language = {en} } @incollection{GkatzogiasVeljkovivPohorylesetal.2022, author = {Gkatzogias, Konstantinos and Veljkoviv, Ana and Pohoryles, Daniel A. and Tsionis, Georgios and Bournas, Dionysios A. and Crowley, Helen and Norl{\´e}n, Hedvig and Butenweg, Christoph and Gervasio, Helena and Manfredi, Vincenzo and Masi, Angelo and Zaharieva, Roumiana}, title = {Policy practice and regional impact assessment for building renovation}, series = {REEBUILD Integrated Techniques for the Seismic Strengthening \& Energy Efficiency of Existing Buildings}, booktitle = {REEBUILD Integrated Techniques for the Seismic Strengthening \& Energy Efficiency of Existing Buildings}, editor = {Gkatzogias, Konstantinos and Tsionis, Georgios}, publisher = {Publications Office of the European Union}, address = {Luxembourg}, isbn = {978-92-76-60454-9}, issn = {1831-9424}, doi = {10.2760/883122}, pages = {1 -- 68}, year = {2022}, abstract = {The work presented in this report provides scientific support to building renovation policies in the EU by promoting a holistic point of view on the topic. Integrated renovation can be seen as a nexus between European policies on disaster resilience, energy efficiency and circularity in the building sector. An overview of policy measures for the seismic and energy upgrading of buildings across EU Member States identified only a few available measures for combined upgrading. Regulatory framework, financial instruments and digital tools similar to those for energy renovation, together with awareness and training may promote integrated renovation. A framework for regional prioritisation of building renovation was put forward, considering seismic risk, energy efficiency, and socioeconomic vulnerability independently and in an integrated way. Results indicate that prioritisation of building renovation is a multidimensional problem. Depending on priorities, different integrated indicators should be used to inform policies and accomplish the highest relative or most spread impact across different sectors. The framework was further extended to assess the impact of renovation scenarios across the EU with a focus on priority regions. Integrated renovation can provide a risk-proofed, sustainable, and inclusive built environment, presenting an economic benefit in the order of magnitude of the highest benefit among the separate interventions. Furthermore, it presents the unique capability of reducing fatalities and energy consumption at the same time and, depending on the scenario, to a greater extent.}, language = {en} } @incollection{WeberBomholtButenweg2022, author = {Weber, Felix and Bomholt, Frederik and Butenweg, Christoph}, title = {Erdbeben- und Schwingungsschutz von Bauwerken}, series = {2023 BetonKalender: Wasserundurchl{\"a}ssiger Beton, Br{\"u}ckenbau}, booktitle = {2023 BetonKalender: Wasserundurchl{\"a}ssiger Beton, Br{\"u}ckenbau}, editor = {Bergmeister, Konrad and Fingerloos, Frank and W{\"o}rner, Johann-Dietrich}, publisher = {Ernst \& Sohn}, address = {Berlin}, isbn = {9783433611180}, doi = {10.1002/9783433611180.ch16}, pages = {779 -- 859}, year = {2022}, abstract = {Dieser Beitrag beschreibt die herk{\"o}mmlichen Maßnahmen wie die Kapazit{\"a}tsbemessung der Tragwerksstruktur, die Isolation des Bauwerks mittels Basisisolatoren, die D{\"a}mpfungserh{\"o}hung der Struktur mittels Inter-Story-D{\"a}mpfern und die Schwingungsreduktion mittels Schwingungstilgern gegen Einwirkungen durch Erdbeben, Wind, Verkehr und Personen auf die Bauwerke. Erg{\"a}nzend wird die erdbebengerechte Auslegung und Isolation von nichttragenden Bauteilen behandelt. F{\"u}r die betrachteten Systeme werden die Bewegungsdifferenzialgleichungen unter Ber{\"u}cksichtigung der wesentlichen Nichtlinearit{\"a}ten angegeben. Die vorgestellten Weiterentwicklungen in den Bereichen der Basisisolatoren, D{\"a}mpfern und Schwingungstilgern zeigen, dass das modellbasierte Design mittels Simulation ein sehr effektives, {\"o}konomisches und dank der heutigen Computerleistung auch zeiteffizientes Werkzeug darstellt.}, language = {de} } @incollection{ButenwegThierauf1999, author = {Butenweg, Christoph and Thierauf, G.}, title = {Automatic design of reinforced concrete structures with parallel computing}, series = {Innovative computational methods for structural mechanics}, booktitle = {Innovative computational methods for structural mechanics}, editor = {Papadrakakis, M. and Topping, B.H.V.}, publisher = {Saxe-Coburg Publication}, address = {Edinburgh}, isbn = {1-874672-05-9}, doi = {10.4203/csets.1.14}, pages = {305 -- 318}, year = {1999}, abstract = {A concept for the analysis and optimal design of reinforced concrete structures is described. It is based on a nonlinear optimization algorithm and a finite element program for linear and nonlinear analysis of structures. With the aim of minimal cost design a two stage optimization using efficient gradient algorithm is developed. The optimization problems on global (structural) and local (crosssectional) level are formulated. A parallelization concept for solving the two stage optimization problem in minimal time is presented. Examples are included to illustrate the practical use and the effectively of the parallelization in the area of engineering design.}, language = {en} } @incollection{MeskourisButenwegKalkeretal.2007, author = {Meskouris, Konstantin and Butenweg, Christoph and Kalker, Ines and Mistler, Michael}, title = {Numerical simulation of historic masonry buildings}, series = {Antike Erdbeben im alpinen und zirkumalpinen Raum : Befunde und Probleme in arch{\"a}ologischer, historischer und seismologischer Sicht ; Beitr{\"a}ge des Interdisziplin{\"a}ren Workshops Schloss Hohenkammer, 14./15. Mai 2004 = Earthquakes in antiquity in the alpine and circum-alpine region / Gerhard H. Waldherr ; Anselm Smolka (Hrsg.) (Geographica Historica ; 24)}, booktitle = {Antike Erdbeben im alpinen und zirkumalpinen Raum : Befunde und Probleme in arch{\"a}ologischer, historischer und seismologischer Sicht ; Beitr{\"a}ge des Interdisziplin{\"a}ren Workshops Schloss Hohenkammer, 14./15. Mai 2004 = Earthquakes in antiquity in the alpine and circum-alpine region / Gerhard H. Waldherr ; Anselm Smolka (Hrsg.) (Geographica Historica ; 24)}, publisher = {Franz Steiner Verlag}, address = {Stuttgart}, isbn = {978-3-515-09030-8 ; 3-515-09030-4}, pages = {171 -- 189}, year = {2007}, language = {en} } @incollection{MeskourisButenweg2008, author = {Meskouris, Konstantin and Butenweg, Christoph}, title = {Erdbebensichere Auslegung von Bauwerken nach DIN 4149:2005}, series = {Betonkalender 2008: Konstruktiver Wasserbau, erdbebensicheres Bauen. Band 2}, booktitle = {Betonkalender 2008: Konstruktiver Wasserbau, erdbebensicheres Bauen. Band 2}, publisher = {Ernst \& Sohn}, address = {Berlin}, isbn = {978-3-433-01839-2 (Print) ; 978-3-433-01854-5 (E-Book)}, doi = {10.1002/9783433600702.ch5}, pages = {1 -- 54}, year = {2008}, language = {de} } @incollection{ButenwegGellert2007, author = {Butenweg, Christoph and Gellert, Christoph}, title = {Berechnung und Bemessung von durch Erdbeben beanspruchten Mauerwerksbauten nach DIN 4149 (04.2005)}, series = {Mauerwerksbau-Praxis / Schubert ; Schneider ; Schoch (Hrsg.)}, booktitle = {Mauerwerksbau-Praxis / Schubert ; Schneider ; Schoch (Hrsg.)}, publisher = {Werner Verlag}, address = {Berlin}, isbn = {3-9343-6938-3 ; 978-3-9343-6938-2}, pages = {363 -- 393}, year = {2007}, language = {de} } @incollection{ButenwegEbenau1996, author = {Butenweg, Christoph and Ebenau, C.}, title = {Entwicklung eines objekt-orientierten FE-Programms}, series = {Forum Bauinformatik - Junge Wissenschaftler forschen, Cottbus '96}, booktitle = {Forum Bauinformatik - Junge Wissenschaftler forschen, Cottbus '96}, publisher = {VDI-Verlag}, address = {D{\"u}sseldorf}, isbn = {978-3-18-313504-2}, pages = {60 -- 65}, year = {1996}, language = {de} } @incollection{AkimbekovDigelSherelkhanetal.2022, author = {Akimbekov, Nuraly S. and Digel, Ilya and Sherelkhan, Dinara K. and Razzaque, Mohammed S.}, title = {Vitamin D and Phosphate Interactions in Health and Disease}, series = {Phosphate Metabolism}, booktitle = {Phosphate Metabolism}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-91621-3}, doi = {10.1007/978-3-030-91623-7_5}, pages = {37 -- 46}, year = {2022}, abstract = {Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis, maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as calcitriol (1,25(OH)2D), not only increases intestinal calcium and phosphate absorption but also facilitates their renal reabsorption, leading to elevated serum calcium and phosphate levels. The interaction of 1,25(OH)2D with its receptor (VDR) increases the efficiency of intestinal absorption of calcium to 30-40\% and phosphate to nearly 80\%. Serum phosphate levels can also influence 1,25 (OH)2D and fibroblast growth factor 23 (FGF23) levels, i.e., higher phosphate concentrations suppress vitamin D activation and stimulate parathyroid hormone (PTH) release, while a high FGF23 serum level leads to reduced vitamin D synthesis. In the vitamin D-deficient state, the intestinal calcium absorption decreases and the secretion of PTH increases, which in turn causes the stimulation of 1,25(OH)2D production, resulting in excessive urinary phosphate loss. Maintenance of phosphate homeostasis is essential as hyperphosphatemia is a risk factor of cardiovascular calcification, chronic kidney diseases (CKD), and premature aging, while hypophosphatemia is usually associated with rickets and osteomalacia. This chapter elaborates on the possible interactions between vitamin D and phosphate in health and disease.}, language = {en} } @incollection{Alexopoulos2013, author = {Alexopoulos, Spiros}, title = {Biomass technology and bio-fuels: Heating/cooling and power}, series = {Renewable energy systems : theory, innovations, and intelligent applications / eds.: Socrates Kaplanis and Eleni Kaplani}, booktitle = {Renewable energy systems : theory, innovations, and intelligent applications / eds.: Socrates Kaplanis and Eleni Kaplani}, publisher = {Nova Science Publ.}, address = {Hauppauge, NY}, isbn = {9781624177415}, pages = {501 -- 523}, year = {2013}, language = {en} } @incollection{DigelMansurovBiisenbaevetal.2012, author = {Digel, Ilya and Mansurov, Zulkhair and Biisenbaev, Makhmut and Savitskaya, Irina and Kistaubaeva, Aida and Akimbekov, Nuraly S. and Zhubanova, Azhar}, title = {Heterogeneous Composites on the Basis of Microbial Cells and Nanostructured Carbonized Sorbents}, series = {Composites and Their Applications}, booktitle = {Composites and Their Applications}, editor = {Hu, Ning}, publisher = {Intech}, address = {London}, isbn = {978-953-51-0706-4}, doi = {10.5772/47796}, pages = {249 -- 272}, year = {2012}, abstract = {The fact that microorganisms prefer to grow on liquid/solid phase surfaces rather than in the surrounding aqueous phase was noticed long time ago [1]. Virtually any surface - animal, mineral, or vegetable - is a subject for microbial colonization and subsequent biofilm formation. It would be adequate to name just a few notorious examples on microbial colonization of contact lenses, ship hulls, petroleum pipelines, rocks in streams and all kinds of biomedical implants. The propensity of microorganisms to become surface-bound is so profound and ubiquitous that it vindicates the advantages for attached forms over their free-ranging counterparts [2]. Indeed, from ecological and evolutionary standpoints, for many microorganisms the surface-bound state means dwelling in nutritionally favorable, non-hostile environments [3]. Therefore, in most of natural and artificial ecosystems surface-associated microorganisms vastly outnumber organisms in suspension and often organize into complex communities with features that differ dramatically from those of free cells [4].}, language = {en} } @incollection{DigelSadykovTemizArtmannetal.2015, author = {Digel, Ilya and Sadykov, R. and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard}, title = {Changes in intestinal microflora in rats induced by oral exposure to low lead (II) concentrations}, series = {Lead Exposure and Poisoning: Clinical Symptoms, Medical Management and Preventive Strategies}, booktitle = {Lead Exposure and Poisoning: Clinical Symptoms, Medical Management and Preventive Strategies}, publisher = {Nova Science Publ.}, isbn = {9781634826990}, pages = {75 -- 99}, year = {2015}, language = {en} } @incollection{DachwaldUlamecKowalskietal.2023, author = {Dachwald, Bernd and Ulamec, Stephan and Kowalski, Julia and Boxberg, Marc S. and Baader, Fabian and Biele, Jens and K{\"o}mle, Norbert}, title = {Ice melting probes}, series = {Handbook of Space Resources}, booktitle = {Handbook of Space Resources}, editor = {Badescu, Viorel and Zacny, Kris and Bar-Cohen, Yoseph}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-97912-6 (Print)}, doi = {10.1007/978-3-030-97913-3_29}, pages = {955 -- 996}, year = {2023}, abstract = {The exploration of icy environments in the solar system, such as the poles of Mars and the icy moons (a.k.a. ocean worlds), is a key aspect for understanding their astrobiological potential as well as for extraterrestrial resource inspection. On these worlds, ice melting probes are considered to be well suited for the robotic clean execution of such missions. In this chapter, we describe ice melting probes and their applications, the physics of ice melting and how the melting behavior can be modeled and simulated numerically, the challenges for ice melting, and the required key technologies to deal with those challenges. We also give an overview of existing ice melting probes and report some results and lessons learned from laboratory and field tests.}, language = {en} } @incollection{LuczakWolfSchlicketal.1999, author = {Luczak, Holger and Wolf, Martin R. and Schlick, Christopher and Springer, J. and Foltz, Christian}, title = {Personenorientierte Arbeitsprozesse und Kommunikationsforrnen}, series = {Integration von Entwicklungssystemen in Ingenieuranwendungen : substantielle Verbesserung der Entwicklungsprozesse}, booktitle = {Integration von Entwicklungssystemen in Ingenieuranwendungen : substantielle Verbesserung der Entwicklungsprozesse}, editor = {Nagl, Walter}, publisher = {Springer}, address = {Berlin}, isbn = {3-540-63920-9}, pages = {403 -- 422}, year = {1999}, language = {de} } @incollection{MansurovJandosovChenchiketal.2020, author = {Mansurov, Zulkhair A. and Jandosov, Jakpar and Chenchik, D. and Azat, Seitkhan and Savitskaya, Irina S. and Kistaubaeva, Aida and Akimbekov, Nuraly S. and Digel, Ilya and Zhubanova, Azhar Achmet}, title = {Biocomposite Materials Based on Carbonized Rice Husk in Biomedicine and Environmental Applications}, series = {Carbon Nanomaterials in Biomedicine and the Environment}, booktitle = {Carbon Nanomaterials in Biomedicine and the Environment}, publisher = {Jenny Stanford Publishing Pte. Ltd.}, address = {Singapore}, isbn = {978-981-4800-27-3}, doi = {10.1201/9780429428647-2}, pages = {3 -- 32}, year = {2020}, abstract = {This chapter describes the prospects for biomedical and environmental engineering applications of heterogeneous materials based on nanostructured carbonized rice husk. Efforts in engineering enzymology are focused on the following directions: development and optimization of immobilization methods leading to novel biotechnological and biomedical applications; construction of biocomposite materials based on individual enzymes, multi-enzyme complexes and whole cells, targeted on realization of specific industrial processes. Molecular biological and biochemical studies on cell adhesion focus predominantly on identification, isolation and structural analysis of attachment-responsible biological molecules and their genetic determinants. The chapter provides a short overview of applications of the biocomposite materials based of nanostructured carbonized adsorbents. It emphasizes that further studies and better understanding of the interactions between CNS and microbial cells are necessary. The future use of living cells as biocatalysts, especially in the environmental field, needs more systematic investigations of the microbial adsorption phenomenon.}, language = {en} } @incollection{ButenwegHoltschoppen2019, author = {Butenweg, Christoph and Holtschoppen, Britta}, title = {Seismic design of structures and components in industrial units}, series = {Structural Dynamics with Applications in Earthquake and Wind Engineering}, booktitle = {Structural Dynamics with Applications in Earthquake and Wind Engineering}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-57550-5}, doi = {10.1007/978-3-662-57550-5_5}, pages = {359 -- 481}, year = {2019}, abstract = {Industrial units consist of the primary load-carrying structure and various process engineering components, the latter being by far the most important in financial terms. In addition, supply structures such as free-standing tanks and silos are usually required for each plant to ensure the supply of material and product storage. Thus, for the earthquake-proof design of industrial plants, design and construction rules are required for the primary structures, the secondary structures and the supply structures. Within the framework of these rules, possible interactions of primary and secondary structures must also be taken into account. Importance factors are used in seismic design in order to take into account the usually higher risk potential of an industrial unit compared to conventional building structures. Industrial facilities must be able to withstand seismic actions because of possibly wide-ranging damage consequences in addition to losses due to production standstill and the destruction of valuable equipment. The chapter presents an integrated concept for the seismic design of industrial units based on current seismic standards and the latest research results. Special attention is devoted to the seismic design of steel thin-walled silos and tank structures.}, language = {en} } @incollection{IbanezSanchezWolf2020, author = {Ibanez-Sanchez, Gema and Wolf, Martin R.}, title = {Interactive Process Mining-Induced Change Management Methodology for Healthcare}, series = {Interactive Process Mining in Healthcare}, booktitle = {Interactive Process Mining in Healthcare}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-53993-1 (Online)}, doi = {10.1007/978-3-030-53993-1_16}, pages = {267 -- 293}, year = {2020}, abstract = {The adoption of the Digital Health Transformation is a tremendous paradigm change in health organizations, which is not a trivial process in reality. For that reason, in this chapter, it is proposed a methodology with the objective to generate a changing culture in healthcare organisations. Such a change culture is essential for the successful implementation of any supporting methods like Interactive Process Mining. It needs to incorporate (mostly) new ways of team-based and evidence-based approaches for solving structural problems in a digital healthcare environment.}, language = {en} } @incollection{ButenwegKubalskiMarinkovicetal.2016, author = {Butenweg, Christoph and Kubalski, Thomas and Marinkovic, Marko and Pfetzing, Thomas and Ismail, Mohammed and Fehling, Ekkehard}, title = {Ausfachungen aus Ziegelmauerwerk}, series = {Mauerwerk-Kalender 2016: Baustoffe, Sanierung, Eurocode-Praxis}, booktitle = {Mauerwerk-Kalender 2016: Baustoffe, Sanierung, Eurocode-Praxis}, publisher = {Ernst \& Sohn}, address = {Berlin}, isbn = {978-3-433-03131-5}, year = {2016}, language = {de} } @incollection{Butenweg2017, author = {Butenweg, Christoph}, title = {Passt, wackelt und hat Luft: Mauerwerksbauten aus Leichtbeton in Erdbebengebieten}, series = {Beton-Bauteile, 65. Ausgabe (2017): Entwerfen - Planen - Ausf{\"u}hren}, booktitle = {Beton-Bauteile, 65. Ausgabe (2017): Entwerfen - Planen - Ausf{\"u}hren}, publisher = {Bauverl.}, address = {G{\"u}tersloh}, isbn = {978-3-7625-3676-5}, pages = {136 -- 140}, year = {2017}, language = {de} } @incollection{BorggrafeOhndorfDachwaldetal.2012, author = {Borggrafe, Andreas and Ohndorf, Andreas and Dachwald, Bernd and Seboldt, Wolfgang}, title = {Analysis of interplanetary solar sail trajectories with attitude dynamics}, series = {Dynamics and Control of Space Systems 2012}, booktitle = {Dynamics and Control of Space Systems 2012}, publisher = {Univelt Inc}, address = {San Diego}, isbn = {978-0-87703-587-9}, pages = {1553 -- 1569}, year = {2012}, abstract = {We present a new approach to the problem of optimal control of solar sails for low-thrust trajectory optimization. The objective was to find the required control torque magnitudes in order to steer a solar sail in interplanetary space. A new steering strategy, controlling the solar sail with generic torques applied about the spacecraft body axes, is integrated into the existing low-thrust trajectory optimization software InTrance. This software combines artificial neural networks and evolutionary algorithms to find steering strategies close to the global optimum without an initial guess. Furthermore, we implement a three rotational degree-of-freedom rigid-body attitude dynamics model to represent the solar sail in space. Two interplanetary transfers to Mars and Neptune are chosen to represent typical future solar sail mission scenarios. The results found with the new steering strategy are compared to the existing reference trajectories without attitude dynamics. The resulting control torques required to accomplish the missions are investigated, as they pose the primary requirements to a real on-board attitude control system.}, language = {en} } @incollection{WolfFoltzLuczak2003, author = {Wolf, Martin R. and Foltz, Christian and Luczak, Holger}, title = {Gestaltung und Evaluation eines Groupware-Konzepts}, series = {Modelle, Werkzeuge und Infrastrukturen zur Unterst{\"u}tzung von Entwicklungsprozessen}, booktitle = {Modelle, Werkzeuge und Infrastrukturen zur Unterst{\"u}tzung von Entwicklungsprozessen}, editor = {Nagl, Manfred}, publisher = {Wiley-VCH}, address = {Weinheim}, isbn = {3-527-27769-2}, pages = {359 -- 360}, year = {2003}, language = {de} } @incollection{LuczakWolfMuehlfelder2001, author = {Luczak, Holger and Wolf, Martin R. and M{\"u}hlfelder, M.}, title = {Arbeitswissenschaft}, series = {CSCW-Kompendium : Lehr- und Handbuch zum computerunterst{\"u}tzten kooperativen Arbeiten ; mit 9 Tabellen}, booktitle = {CSCW-Kompendium : Lehr- und Handbuch zum computerunterst{\"u}tzten kooperativen Arbeiten ; mit 9 Tabellen}, editor = {Schwabe, Gerhard}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-540-67552-5}, doi = {10.1007/978-3-642-56848-0_2}, pages = {7 -- 14}, year = {2001}, abstract = {Unter Arbeit wird das T{\"a}tigsein des Menschen verstanden, bei dem dieser mit anderen Menschen und (technischen) Hilfsmitteln in Interaktion tritt, um unter wirtschaftlichen Zielsetzungen G{\"u}ter und Dienstleistungen zu erstellen (Luczak, 1998a). Arbeit dient direkt oder indirekt der Erhaltung der eigenen Existenz und der Existenz der Gesellschaft. Arbeit ist deshalb eine besondere Form des T{\"a}tigseins neben anderen wie Spiel, Sport, Lemen usw.}, language = {de} } @incollection{PieperWaehlisch2017, author = {Pieper, Martin and W{\"a}hlisch, Georg}, title = {Mehrwert von E-Learning durch f{\"a}cher{\"u}bergreifenden Einsatz}, series = {Teaching is Touching the Future \& ePS 2016 - Kompetenzorientiertes Lehren, Lernen und Pr{\"u}fen}, booktitle = {Teaching is Touching the Future \& ePS 2016 - Kompetenzorientiertes Lehren, Lernen und Pr{\"u}fen}, publisher = {UVW Universit{\"a}tsverlag Webler}, address = {Bielefeld}, isbn = {978-3-946017-05-9}, pages = {193 -- 196}, year = {2017}, language = {de} } @incollection{NiemuellerReuterEwertetal.2015, author = {Niemueller, Tim and Reuter, Sebastian and Ewert, Daniel and Ferrein, Alexander and Jeschke, Sabina and Lakemeyer, Gerhard}, title = {Decisive Factors for the Success of the Carologistics RoboCup Team in the RoboCup Logistics League 2014}, series = {RoboCup 2014: Robot World Cup XVIII}, booktitle = {RoboCup 2014: Robot World Cup XVIII}, publisher = {Springer}, isbn = {978-3-319-18615-3}, pages = {155 -- 167}, year = {2015}, language = {en} } @incollection{BergenerDelfmannEggertetal.2010, author = {Bergener, Philipp and Delfmann, Patrick and Eggert, Mathias and Fritz, Fleur and Heddier, Marcel and Herring, Eva-Maria and Hofmann, Sara and Knackstedt, Ralf and Meil{\"a}nder, Dominique and Meyer, Eric and R{\"a}ckers, Michael and Seiler, Julia}, title = {Forschungsperspektiven im Kontext Informationstechnik und Recht}, series = {IT-Risiken: Ursachen, Methoden, Forschungsperspektiven, Arbeitsberichte des Instituts f{\"u}r Wirtschaftsinformatik}, booktitle = {IT-Risiken: Ursachen, Methoden, Forschungsperspektiven, Arbeitsberichte des Instituts f{\"u}r Wirtschaftsinformatik}, number = {128}, editor = {Becker, J{\"o}rg and Bergener, Philipp and Eggert, Mathias and Heddier, Marcel and Hofmann, Sara and Knackstedt, Ralf and R{\"a}ckers, Michael}, publisher = {Institut f{\"u}r Wirtschaftsinformatik}, address = {M{\"u}nster}, issn = {1438-3985}, pages = {115 -- 147}, year = {2010}, language = {de} } @incollection{DachwaldOhndorf2019, author = {Dachwald, Bernd and Ohndorf, Andreas}, title = {Global optimization of continuous-thrust trajectories using evolutionary neurocontrol}, series = {Modeling and Optimization in Space Engineering}, booktitle = {Modeling and Optimization in Space Engineering}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-10501-3}, doi = {10.1007/978-3-030-10501-3_2}, pages = {33 -- 57}, year = {2019}, abstract = {Searching optimal continuous-thrust trajectories is usually a difficult and time-consuming task. The solution quality of traditional optimal-control methods depends strongly on an adequate initial guess because the solution is typically close to the initial guess, which may be far from the (unknown) global optimum. Evolutionary neurocontrol attacks continuous-thrust optimization problems from the perspective of artificial intelligence and machine learning, combining artificial neural networks and evolutionary algorithms. This chapter describes the method and shows some example results for single- and multi-phase continuous-thrust trajectory optimization problems to assess its performance. Evolutionary neurocontrol can explore the trajectory search space more exhaustively than a human expert can do with traditional optimal-control methods. Especially for difficult problems, it usually finds solutions that are closer to the global optimum. Another fundamental advantage is that continuous-thrust trajectories can be optimized without an initial guess and without expert supervision.}, language = {en} } @incollection{NiemuellerLakemeyerReuteretal.2017, author = {Niemueller, T. and Lakemeyer, G. and Reuter, S. and Jeschke, S. and Ferrein, Alexander}, title = {Benchmarking of Cyber-Physical Systems in Industrial Robotics: The RoboCup Logistics League as a CPS Benchmark Blueprint}, series = {Cyber-Physical Systems: Foundations, Principles and Applications}, booktitle = {Cyber-Physical Systems: Foundations, Principles and Applications}, publisher = {Academic Press}, address = {London}, doi = {10.1016/B978-0-12-803801-7.00013-4}, pages = {193 -- 207}, year = {2017}, abstract = {In the future, we expect manufacturing companies to follow a new paradigm that mandates more automation and autonomy in production processes. Such smart factories will offer a variety of production technologies as services that can be combined ad hoc to produce a large number of different product types and variants cost-effectively even in small lot sizes. This is enabled by cyber-physical systems that feature flexible automated planning methods for production scheduling, execution control, and in-factory logistics. During development, testbeds are required to determine the applicability of integrated systems in such scenarios. Furthermore, benchmarks are needed to quantify and compare system performance in these industry-inspired scenarios at a comprehensible and manageable size which is, at the same time, complex enough to yield meaningful results. In this chapter, based on our experience in the RoboCup Logistics League (RCLL) as a specific example, we derive a generic blueprint for how a holistic benchmark can be developed, which combines a specific scenario with a set of key performance indicators as metrics to evaluate the overall integrated system and its components.}, language = {de} } @incollection{RebelHueningScholletal.2015, author = {Rebel, S{\"o}ren and H{\"u}ning, Felix and Scholl, Ingrid and Ferrein, Alexander}, title = {MQOne: Low-cost design for a rugged-terrain robot platform}, series = {Intelligent robotics and applications : 8th International Conference, ICIRA 2015, Portsmouth, UK, August 24-27, 2015, Proceedings, Part II (Lecture notes in computer science : vol. 9245)}, booktitle = {Intelligent robotics and applications : 8th International Conference, ICIRA 2015, Portsmouth, UK, August 24-27, 2015, Proceedings, Part II (Lecture notes in computer science : vol. 9245)}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-22875-4 (print) ; 978-3-319-22876-1 (E-Book)}, doi = {10.1007/978-3-319-22876-1_19}, pages = {209 -- 221}, year = {2015}, abstract = {Rugged terrain robot designs are important for field robotics missions. A number of commercial platforms are available, however, at an impressive price. In this paper, we describe the hardware and software component of a low-cost wheeled rugged-terrain robot. The robot is based on an electric children quad bike and is modified to be driven by wire. In terms of climbing properties, operation time and payload it can compete with some of the commercially available platforms, but at a far lower price.}, language = {en} } @incollection{ArtmannMeruvuKizildagetal.2018, author = {Artmann, Gerhard and Meruvu, Haritha and Kizildag, Sefa and Temiz Artmann, Ayseg{\"u}l}, title = {Functional Toxicology and Pharmacology Test of Cell Induced Mechanical Tensile Stress in 2D and 3D Tissue Cultures}, series = {Biological, Physical and Technical Basics of Cell Engineering}, booktitle = {Biological, Physical and Technical Basics of Cell Engineering}, editor = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya}, publisher = {Springer}, address = {Singapore}, isbn = {978-981-10-7904-7}, doi = {10.1007/978-981-10-7904-7_7}, pages = {157 -- 192}, year = {2018}, abstract = {Mechanical forces/tensile stresses are critical determinants of cellular growth, differentiation and migration patterns in health and disease. The innovative "CellDrum technology" was designed for measuring mechanical tensile stress of cultured cell monolayers/thin tissue constructs routinely. These are cultivated on very thin silicone membranes in the so-called CellDrum. The cell layers adhere firmly to the membrane and thus transmit the cell forces generated. A CellDrum consists of a cylinder which is sealed from below with a 4 μm thick, biocompatible, functionalized silicone membrane. The weight of cell culture medium bulbs the membrane out downwards. Membrane indentation is measured. When cells contract due to drug action, membrane, cells and medium are lifted upwards. The induced indentation changes allow for lateral drug induced mechanical tension quantification of the micro-tissues. With hiPS-induced (human) Cardiomyocytes (CM) the CellDrum opens new perspectives of individualized cardiac drug testing. Here, monolayers of self-beating hiPS-CMs were grown in CellDrums. Rhythmic contractions of the hiPS-cells induce membrane up-and-down deflections. The recorded cycles allow for single beat amplitude, single beat duration, integration of the single beat amplitude over the beat time and frequency analysis. Dose effects of agonists and antagonists acting on Ca2+ channels were sensitively and highly reproducibly observed. Data were consistent with published reference data as far as they were available. The combination of the CellDrum technology with hiPS-Cardiomyocytes offers a fast, facile and precise system for pharmacological and toxicological studies. It allows new preclinical basic as well as applied research in pharmacolgy and toxicology.}, language = {en} } @incollection{FrotscherGossmannRaatschenetal.2015, author = {Frotscher, Ralf and Goßmann, Matthias and Raatschen, Hans-J{\"u}rgen and Temiz Artmann, Ayseg{\"u}l and Staat, Manfred}, title = {Simulation of cardiac cell-seeded membranes using the edge-based smoothed FEM}, series = {Shell and membrane theories in mechanics and biology. (Advanced structured materials ; 45)}, booktitle = {Shell and membrane theories in mechanics and biology. (Advanced structured materials ; 45)}, publisher = {Springer}, address = {Heidelberg}, isbn = {978-3-319-02534-6 ; 978-3-319-02535-3}, pages = {187 -- 212}, year = {2015}, abstract = {We present an electromechanically coupled Finite Element model for cardiac tissue. It bases on the mechanical model for cardiac tissue of Hunter et al. that we couple to the McAllister-Noble-Tsien electrophysiological model of purkinje fibre cells. The corresponding system of ordinary differential equations is implemented on the level of the constitutive equations in a geometrically and physically nonlinear version of the so-called edge-based smoothed FEM for plates. Mechanical material parameters are determined from our own pressure-deflection experimental setup. The main purpose of the model is to further examine the experimental results not only on mechanical but also on electrophysiological level down to ion channel gates. Moreover, we present first drug treatment simulations and validate the model with respect to the experiments.}, language = {en} } @incollection{BhattaraiFrotscherStaat2018, author = {Bhattarai, Aroj and Frotscher, Ralf and Staat, Manfred}, title = {Computational Analysis of Pelvic Floor Dysfunction}, series = {Women's Health and Biomechanics}, booktitle = {Women's Health and Biomechanics}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-71574-2}, doi = {10.1007/978-3-319-71574-2_17}, pages = {217 -- 230}, year = {2018}, abstract = {Pelvic floor dysfunction (PFD) is characterized by the failure of the levator ani (LA) muscle to maintain the pelvic hiatus, resulting in the descent of the pelvic organs below the pubococcygeal line. This chapter adopts the modified Humphrey material model to consider the effect of the muscle fiber on passive stretching of the LA muscle. The deformation of the LA muscle subjected to intra-abdominal pressure during Valsalva maneuver is compared with the magnetic resonance imaging (MRI) examination of a nulliparous female. Numerical result shows that the fiber-based Humphrey model simulates the muscle behavior better than isotropic constitutive models. Greater posterior movement of the LA muscle widens the levator hiatus due to lack of support from the anococcygeal ligament and the perineal structure as a consequence of birth-related injury and aging. Old and multiparous females with uncontrolled urogenital and rectal hiatus tend to develop PFDs such as prolapse and incontinence.}, language = {en} }