@incollection{CzarneckiHongSchmitzetal.2021, author = {Czarnecki, Christian and Hong, Chin-Gi and Schmitz, Manfred and Dietze, Christian}, title = {Enabling digital transformation through cognitive robotic process automation at Deutsche Telekom Services Europe}, series = {Digitalization Cases Vol. 2 : Mastering digital transformation for global business}, booktitle = {Digitalization Cases Vol. 2 : Mastering digital transformation for global business}, editor = {Urbach, Nils and R{\"o}glinger, Maximilian and Kautz, Karlheinz and Alias, Rose Alinda and Saunders, Carol and Wiener, Martin}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-80002-4 (Print)}, doi = {10.1007/978-3-030-80003-1}, pages = {123 -- 138}, year = {2021}, abstract = {Subject of this case is Deutsche Telekom Services Europe (DTSE), a service center for administrative processes. Due to the high volume of repetitive tasks (e.g., 100k manual uploads of offer documents into SAP per year), automation was identified as an important strategic target with a high management attention and commitment. DTSE has to work with various backend application systems without any possibility to change those systems. Furthermore, the complexity of administrative processes differed. When it comes to the transfer of unstructured data (e.g., offer documents) to structured data (e.g., MS Excel files), further cognitive technologies were needed.}, language = {en} } @incollection{CzarneckiFettke2021, author = {Czarnecki, Christian and Fettke, Peter}, title = {Robotic process automation : Positioning, structuring, and framing the work}, series = {Robotic process automation : Management, technology, applications}, booktitle = {Robotic process automation : Management, technology, applications}, editor = {Czarnecki, Christian and Fettke, Peter}, publisher = {De Gruyter}, address = {Oldenbourg}, isbn = {978-3-11-067668-6 (Print)}, doi = {10.1515/9783110676693-202}, pages = {3 -- 24}, year = {2021}, abstract = {Robotic process automation (RPA) has attracted increasing attention in research and practice. This chapter positions, structures, and frames the topic as an introduction to this book. RPA is understood as a broad concept that comprises a variety of concrete solutions. From a management perspective RPA offers an innovative approach for realizing automation potentials, whereas from a technical perspective the implementation based on software products and the impact of artificial intelligence (AI) and machine learning (ML) are relevant. RPA is industry-independent and can be used, for example, in finance, telecommunications, and the public sector. With respect to RPA this chapter discusses definitions, related approaches, a structuring framework, a research framework, and an inside as well as outside architectural view. Furthermore, it provides an overview of the book combined with short summaries of each chapter.}, language = {en} } @incollection{Fissabre2022, author = {Fissabre, Anke}, title = {Die Bauten des j{\"u}dischen Friedhofs an der L{\"u}tticher Straße}, series = {Der J{\"u}dische Friedhof Aachen}, booktitle = {Der J{\"u}dische Friedhof Aachen}, editor = {Dux, Holger A.}, publisher = {Mayersche Buchhandlung Aachen GmbH}, address = {Aachen}, isbn = {978-3-87519-266-7}, pages = {51 -- 69}, year = {2022}, language = {de} } @incollection{Fissabre2022, author = {Fissabre, Anke}, title = {Ein Entwurf f{\"u}r die Umnutzung der Bauten des j{\"u}dischen Friedhofs an der L{\"u}tticher Straße}, series = {Der j{\"u}dische Friedhof Aachen L{\"u}tticher Straße Aachen}, booktitle = {Der j{\"u}dische Friedhof Aachen L{\"u}tticher Straße Aachen}, editor = {Dux, Holger A.}, publisher = {Mayersche Buchhandlung Aachen GmbH}, address = {Aachen}, isbn = {978-3-87519-266-7}, pages = {71 -- 74}, year = {2022}, language = {de} } @incollection{CzarneckiBensberg2019, author = {Czarnecki, Christian and Bensberg, Frank}, title = {Telekommunikationsunternehmen, Anwendungssysteme f{\"u}r}, series = {Enzyklop{\"a}die der Wirtschaftsinformatik}, booktitle = {Enzyklop{\"a}die der Wirtschaftsinformatik}, publisher = {Gito}, address = {Berlin}, pages = {1 -- 3}, year = {2019}, language = {de} } @incollection{Czarnecki2019, author = {Czarnecki, Christian}, title = {Robotergesteuerte Prozessautomatisierung}, series = {Enzyklop{\"a}die der Wirtschaftsinformatik}, booktitle = {Enzyklop{\"a}die der Wirtschaftsinformatik}, publisher = {Gito}, address = {Berlin}, pages = {1 -- 3}, year = {2019}, language = {de} } @incollection{Fissabre2022, author = {Fissabre, Anke}, title = {kirchen-bauhaus? - Die Kunstgewerbeschule in Aachen unter Rudolf Schwarz}, series = {Zwischen den Zeiten - Besatzung und Aufbruch in Aachen, 1919-1932}, booktitle = {Zwischen den Zeiten - Besatzung und Aufbruch in Aachen, 1919-1932}, editor = {Soldwisch, Ines and Schmitz, Stefan}, publisher = {Aachener Karnevalsverein (AKV)}, address = {Aachen}, isbn = {978-3-9825016-0-4}, pages = {54 -- 65}, year = {2022}, language = {de} } @incollection{BensbergAuthCzarnecki2021, author = {Bensberg, Frank and Auth, Gunnar and Czarnecki, Christian}, title = {Finding the perfect RPA match : a criteria-based selection method for RPA solutions}, series = {Robotic process automation : Management, technology, applications}, booktitle = {Robotic process automation : Management, technology, applications}, editor = {Czarnecki, Christian and Fettke, Peter}, publisher = {De Gruyter}, address = {Oldenbourg}, isbn = {978-3-11-067677-8}, doi = {10.1515/9783110676693-201}, pages = {47 -- 75}, year = {2021}, abstract = {The benefits of robotic process automation (RPA) are highly related to the usage of commercial off-the-shelf (COTS) software products that can be easily implemented and customized by business units. But, how to find the best fitting RPA product for a specific situation that creates the expected benefits? This question is related to the general area of software evaluation and selection. In the face of more than 75 RPA products currently on the market, guidance considering those specifics is required. Therefore, this chapter proposes a criteria-based selection method specifically for RPA. The method includes a quantitative evaluation of costs and benefits as well as a qualitative utility analysis based on functional criteria. By using the visualization of financial implications (VOFI) method, an application-oriented structure is provided that opposes the total cost of ownership to the time savings times salary (TSTS). For the utility analysis a detailed list of functional criteria for RPA is offered. The whole method is based on a multi-vocal review of scientific and non-scholarly literature including publications by business practitioners, consultants, and vendors. The application of the method is illustrated by a concrete RPA example. The illustrated structures, templates, and criteria can be directly utilized by practitioners in their real-life RPA implementations. In addition, a normative decision process for selecting RPA alternatives is proposed before the chapter closes with a discussion and outlook.}, language = {en} } @incollection{CroonCzarnecki2021, author = {Croon, Philipp and Czarnecki, Christian}, title = {Liability for loss or damages caused by RPA}, series = {Robotic process automation : Management, technology, applications}, booktitle = {Robotic process automation : Management, technology, applications}, editor = {Czarnecki, Christian and Fettke, Peter}, publisher = {De Gruyter}, address = {Oldenbourg}, isbn = {9783110676778}, doi = {10.1515/9783110676693-202}, pages = {135 -- 151}, year = {2021}, abstract = {Intelligent autonomous software robots replacing human activities and performing administrative processes are reality in today's corporate world. This includes, for example, decisions about invoice payments, identification of customers for a marketing campaign, and answering customer complaints. What happens if such a software robot causes a damage? Due to the complete absence of human activities, the question is not trivial. It could even happen that no one is liable for a damage towards a third party, which could create an uncalculatable legal risk for business partners. Furthermore, the implementation and operation of those software robots involves various stakeholders, which result in the unsolvable endeavor of identifying the originator of a damage. Overall it is advisable to all involved parties to carefully consider the legal situation. This chapter discusses the liability of software robots from an interdisciplinary perspective. Based on different technical scenarios the legal aspects of liability are discussed.}, language = {en} } @incollection{SchneiderWisselinkNoelleetal.2021, author = {Schneider, Dominik and Wisselink, Frank and N{\"o}lle, Nikolai and Czarnecki, Christian}, title = {Einfluss von K{\"u}nstlicher Intelligenz auf Customer Journeys am Beispiel von intelligentem Parken}, series = {K{\"u}nstliche Intelligenz in der Anwendung : Rechtliche Aspekte, Anwendungspotenziale und Einsatzszenarien}, booktitle = {K{\"u}nstliche Intelligenz in der Anwendung : Rechtliche Aspekte, Anwendungspotenziale und Einsatzszenarien}, editor = {Barton, Thomas and M{\"u}ller, Christian}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-30935-0 (Print)}, doi = {10.1007/978-3-658-30936-7_7}, pages = {99 -- 122}, year = {2021}, abstract = {Im Konsumentenmarkt entstehen vermehrt neue Anwendungen von K{\"u}nstlicher Intelligenz (KI). Zunehmend dr{\"a}ngen auch Ger{\"a}te und Dienste in den Markt, die eigenst{\"a}ndig {\"u}ber das Internet kommunizieren. Dadurch k{\"o}nnen diese Ger{\"a}te und Dienste mit neuartigen KI-basierten Diensten verbessert werden. Solche Dienste k{\"o}nnen die Art und Weise beeinflussen, wie Kunden kommerzielle Entscheidungen treffen und somit das Kundenerlebnis maßgeblich ver{\"a}ndern. Der Einfluss von KI auf kommerzielle Interaktionen wurde bisher noch nicht umfassend untersucht. Basierend auf einem Framework, welches einen ersten {\"U}berblick {\"u}ber die Effekte von KI auf kommerzielle Interaktionen gibt, wird in diesem Kapitel der Einfluss von KI auf Customer Journeys am konkreten Anwendungsfall des intelligenten Parkens analysiert. Die daraus gewonnenen Erkenntnisse k{\"o}nnen in der Praxis als Grundlage genutzt werden, um das Potenzial von KI zu verstehen und bei der Gestaltung eigener Customer Journeys umzusetzen.}, language = {de} } @incollection{SchneiderWisselinkNoelleetal.2020, author = {Schneider, Dominik and Wisselink, Frank and N{\"o}lle, Nikolai and Czarnecki, Christian}, title = {Influence of artificial intelligence on commercial interactions in the consumer market}, series = {Automatisierung und Personalisierung von Dienstleistungen : Methoden - Potenziale - Einsatzfelder}, booktitle = {Automatisierung und Personalisierung von Dienstleistungen : Methoden - Potenziale - Einsatzfelder}, editor = {Bruhn, Manfred and Hadwich, Karsten}, publisher = {Springer Gabler}, address = {Wiesbaden}, isbn = {978-3-658-30167-5 (Print)}, doi = {10.1007/978-3-658-30168-2_7}, pages = {183 -- 205}, year = {2020}, abstract = {Recently, novel AI-based services have emerged in the consumer market. AI-based services can affect the way consumers take commercial decisions. Research on the influence of AI on commercial interactions is in its infancy. In this chapter, a framework creating a first overview of the influence of AI on commercial interactions is introduced. This framework summarizes the findings of comparing numerous customer journeys of novel AI-based services with corresponding non-AI equivalents.}, language = {en} } @incollection{AuthCzarneckiBensbergetal.2019, author = {Auth, Gunnar and Czarnecki, Christian and Bensberg, Frank and Thor, Andreas}, title = {Digitalisierung des Forschungsprozesses aus Sicht von Forschenden - durch Serviceintegration zum pers{\"o}nlichen Forschungsinformationssystem}, series = {Hochschulen in Zeiten der Digitalisierung : Lehre, Forschung und Organisation}, booktitle = {Hochschulen in Zeiten der Digitalisierung : Lehre, Forschung und Organisation}, editor = {Barton, Thomas and M{\"u}ller, Christian and Seel, Christian}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-26617-2 (Print)}, doi = {10.1007/978-3-658-26618-9_17}, pages = {287 -- 307}, year = {2019}, abstract = {In der Diskussion {\"u}ber die Digitalisierung der Forschung spielt die Frage nach der optimalen IT-Unterst{\"u}tzung f{\"u}r Forschende eine wichtige Rolle. Forschende k{\"o}nnen heute an ihren Hochschulen bzw. Wissenschaftseinrichtungen auf ein breites Angebot interner IT-Dienstleistungen zur{\"u}ckgreifen, das auch kooperative IT-Dienste umfasst, die von mehreren Institutionen in Zusammenarbeit bereitgestellt werden. Außerhalb der eigenen Organisation und des weiteren Verbunds hat sich im Internet zudem ein breites externes Angebot an innovativen, h{\"a}ufig kostenlos nutzbaren Onlinediensten entwickelt. Neben horizontalen Onlinediensten, die sich prinzipiell an jeden Internetnutzer richten (bspw. Dropbox, Twitter, WhatsApp), nimmt auch die Zahl von vertikalen Diensten f{\"u}r wissenschaftliche bzw. Forschungszwecke immer weiter zu (bspw. GoogleScholar, ResearchGate, figshare). F{\"u}r Forschende er{\"o}ffnen sich damit vielf{\"a}ltige neue M{\"o}glichkeiten, ihren individuellen Forschungsprozess durch digitale Werkzeuge zu verbessern. Aufgrund rechtlicher, technischer und personeller Restriktionen k{\"o}nnen jedoch interne Dienstleister bei der Identifizierung, Auswahl und Nutzung externer Onlinedienste nur wenig Unterst{\"u}tzung leisten. Aus einer serviceorientierten Perspektive stehen Forschende zunehmend vor dem Problem, wie sich heterogene IT-Dienste interner und externer Anbieter in den eigenen Forschungsprozess integrieren lassen. Als L{\"o}sungsansatz skizziert das Kapitel das Konzept eines pers{\"o}nlichen Forschungsinformationssystems nach Gesichtspunkten eines digitalen Servicesystems.}, language = {de} } @incollection{BensbergBuscherCzarnecki2019, author = {Bensberg, Frank and Buscher, Gandalf and Czarnecki, Christian}, title = {Digital transformation and IT topics in the consulting industry: a labor market perspective}, series = {Advances in consulting research : recent findings and practical cases}, booktitle = {Advances in consulting research : recent findings and practical cases}, editor = {Nissen, Volker}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-95998-6}, doi = {10.1007/978-3-319-95999-3_16}, pages = {341 -- 357}, year = {2019}, abstract = {Information technologies, such as big data analytics, cloud computing, cyber physical systems, robotic process automation, and the internet of things, provide a sustainable impetus for the structural development of business sectors as well as the digitalization of markets, enterprises, and processes. Within the consulting industry, the proliferation of these technologies opened up the new segment of digital transformation, which focuses on setting up, controlling, and implementing projects for enterprises from a broad range of sectors. These recent developments raise the question, which requirements evolve for IT consultants as important success factors of those digital transformation projects. Therefore, this empirical contribution provides indications regarding the qualifications and competences necessary for IT consultants in the era of digital transformation from a labor market perspective. On the one hand, this knowledge base is interesting for the academic education of consultants, since it supports a market-oriented design of adequate training measures. On the other hand, insights into the competence requirements for consultants are considered relevant for skill and talent management processes in consulting practice. Assuming that consulting companies pursue a strategic human resource management approach, labor market information may also be useful to discover strategic behavioral patterns.}, language = {en} } @incollection{SchmitzDietzeCzarnecki2019, author = {Schmitz, Manfred and Dietze, Christian and Czarnecki, Christian}, title = {Enabling digital transformation through robotic process automation at Deutsche Telekom}, series = {Enabling digital transformation through robotic process automation at Deutsche Telekom}, booktitle = {Enabling digital transformation through robotic process automation at Deutsche Telekom}, editor = {Urbach, Nils and R{\"o}glinger, Maximilian}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-95272-7}, doi = {10.1007/978-3-319-95273-4_2}, pages = {15 -- 33}, year = {2019}, abstract = {Due to the high number of customer contacts, fault clearances, installations, and product provisioning per year, the automation level of operational processes has a significant impact on financial results, quality, and customer experience. Therefore, the telecommunications operator Deutsche Telekom (DT) has defined a digital strategy with the objectives of zero complexity and zero complaint, one touch, agility in service, and disruptive thinking. In this context, Robotic Process Automation (RPA) was identified as an enabling technology to formulate and realize DT's digital strategy through automation of rule-based, routine, and predictable tasks in combination with structured and stable data.}, language = {en} } @incollection{BensbergCzarneckiGrob2022, author = {Bensberg, Frank and Czarnecki, Christian and Grob, Heinz Lothar}, title = {Wirtschaftlichkeitsbewertung von Smart Services mit vollst{\"a}ndigen Finanzpl{\"a}nen}, series = {Smart Services: Band 1: Konzepte - Methoden - Prozesse}, booktitle = {Smart Services: Band 1: Konzepte - Methoden - Prozesse}, editor = {Bruhn, Manfred and Hadwich, Karsten}, publisher = {Springer Gabler}, address = {Wiesbaden}, isbn = {978-3-658-37344-3 (Online)}, doi = {10.1007/978-3-658-37344-3_6}, pages = {225 -- 251}, year = {2022}, abstract = {Dieser Beitrag stellt einen Bewertungsrahmen f{\"u}r Smart Services vor, der auf dem Konzept vollst{\"a}ndiger Finanzpl{\"a}ne (VOFI) basiert. Zun{\"a}chst wird eine IoT-Architektur f{\"u}r Smart Services eingef{\"u}hrt, die die Grundlage f{\"u}r deren Betrachtung aus Sicht der Unternehmensplanung liefert. Hierauf aufbauend wird ein Bewertungsrahmen f{\"u}r die finanzplanorientierte Wirtschaftlichkeitsbewertung von Smart Services geschaffen, mit dem die relevanten Zahlungsfolgen differenziert erfasst werden. Mithilfe des entwickelten VOFI-Systems wird anschließend aufgezeigt, wie mithilfe einer Risikoanalyse die Unsicherheit von Modellparametern ber{\"u}cksichtigt werden kann.}, language = {de} } @incollection{WeberBomholtButenweg2022, author = {Weber, Felix and Bomholt, Frederik and Butenweg, Christoph}, title = {Erdbeben- und Schwingungsschutz von Bauwerken}, series = {2023 BetonKalender: Wasserundurchl{\"a}ssiger Beton, Br{\"u}ckenbau}, booktitle = {2023 BetonKalender: Wasserundurchl{\"a}ssiger Beton, Br{\"u}ckenbau}, editor = {Bergmeister, Konrad and Fingerloos, Frank and W{\"o}rner, Johann-Dietrich}, publisher = {Ernst \& Sohn}, address = {Berlin}, isbn = {9783433611180}, doi = {10.1002/9783433611180.ch16}, pages = {779 -- 859}, year = {2022}, abstract = {Dieser Beitrag beschreibt die herk{\"o}mmlichen Maßnahmen wie die Kapazit{\"a}tsbemessung der Tragwerksstruktur, die Isolation des Bauwerks mittels Basisisolatoren, die D{\"a}mpfungserh{\"o}hung der Struktur mittels Inter-Story-D{\"a}mpfern und die Schwingungsreduktion mittels Schwingungstilgern gegen Einwirkungen durch Erdbeben, Wind, Verkehr und Personen auf die Bauwerke. Erg{\"a}nzend wird die erdbebengerechte Auslegung und Isolation von nichttragenden Bauteilen behandelt. F{\"u}r die betrachteten Systeme werden die Bewegungsdifferenzialgleichungen unter Ber{\"u}cksichtigung der wesentlichen Nichtlinearit{\"a}ten angegeben. Die vorgestellten Weiterentwicklungen in den Bereichen der Basisisolatoren, D{\"a}mpfern und Schwingungstilgern zeigen, dass das modellbasierte Design mittels Simulation ein sehr effektives, {\"o}konomisches und dank der heutigen Computerleistung auch zeiteffizientes Werkzeug darstellt.}, language = {de} } @incollection{GkatzogiasVeljkovivPohorylesetal.2022, author = {Gkatzogias, Konstantinos and Veljkoviv, Ana and Pohoryles, Daniel A. and Tsionis, Georgios and Bournas, Dionysios A. and Crowley, Helen and Norl{\´e}n, Hedvig and Butenweg, Christoph and Gervasio, Helena and Manfredi, Vincenzo and Masi, Angelo and Zaharieva, Roumiana}, title = {Policy practice and regional impact assessment for building renovation}, series = {REEBUILD Integrated Techniques for the Seismic Strengthening \& Energy Efficiency of Existing Buildings}, booktitle = {REEBUILD Integrated Techniques for the Seismic Strengthening \& Energy Efficiency of Existing Buildings}, editor = {Gkatzogias, Konstantinos and Tsionis, Georgios}, publisher = {Publications Office of the European Union}, address = {Luxembourg}, isbn = {978-92-76-60454-9}, issn = {1831-9424}, doi = {10.2760/883122}, pages = {1 -- 68}, year = {2022}, abstract = {The work presented in this report provides scientific support to building renovation policies in the EU by promoting a holistic point of view on the topic. Integrated renovation can be seen as a nexus between European policies on disaster resilience, energy efficiency and circularity in the building sector. An overview of policy measures for the seismic and energy upgrading of buildings across EU Member States identified only a few available measures for combined upgrading. Regulatory framework, financial instruments and digital tools similar to those for energy renovation, together with awareness and training may promote integrated renovation. A framework for regional prioritisation of building renovation was put forward, considering seismic risk, energy efficiency, and socioeconomic vulnerability independently and in an integrated way. Results indicate that prioritisation of building renovation is a multidimensional problem. Depending on priorities, different integrated indicators should be used to inform policies and accomplish the highest relative or most spread impact across different sectors. The framework was further extended to assess the impact of renovation scenarios across the EU with a focus on priority regions. Integrated renovation can provide a risk-proofed, sustainable, and inclusive built environment, presenting an economic benefit in the order of magnitude of the highest benefit among the separate interventions. Furthermore, it presents the unique capability of reducing fatalities and energy consumption at the same time and, depending on the scenario, to a greater extent.}, language = {en} } @incollection{Czarnecki2018, author = {Czarnecki, Christian}, title = {Establishment of a central process governance organization combined with operational process improvements : Insights from a BPM Project at a leading telecommunications operator in the Middle East}, series = {Business process management cases : digital innovation and business transformation in practice}, booktitle = {Business process management cases : digital innovation and business transformation in practice}, editor = {vom Brocke, Jan and Mendling, Jan}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-58306-8}, doi = {10.1007/978-3-319-58307-5}, pages = {57 -- 76}, year = {2018}, abstract = {Because of customer churn, strong competition, and operational inefficiencies, the telecommunications operator ME Telco (fictitious name due to confidentiality) launched a strategic transformation program that included a Business Process Management (BPM) project. Major problems were silo-oriented process management and missing cross-functional transparency. Process improvements were not consistently planned and aligned with corporate targets. Measurable inefficiencies were observed on an operational level, e.g., high lead times and reassignment rates of the incident management process.}, language = {en} } @incollection{PoghossianSchoening2017, author = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Nanomaterial-Modified Capacitive Field-Effect Biosensors}, series = {Springer Series on Chemical Sensors and Biosensors (Methods and Applications)}, booktitle = {Springer Series on Chemical Sensors and Biosensors (Methods and Applications)}, publisher = {Springer}, address = {Berlin, Heidelberg}, doi = {10.1007/5346_2017_2}, pages = {1 -- 25}, year = {2017}, abstract = {The coupling of charged molecules, nanoparticles, and more generally, inorganic/organic nanohybrids with semiconductor field-effect devices based on an electrolyte-insulator-semiconductor (EIS) system represents a very promising strategy for the active tuning of electrochemical properties of these devices and, thus, opening new opportunities for label-free biosensing by the intrinsic charge of molecules. The simplest field-effect sensor is a capacitive EIS sensor, which represents a (bio-)chemically sensitive capacitor. In this chapter, selected examples of recent developments in the field of label-free biosensing using nanomaterial-modified capacitive EIS sensors are summarized. In the first part, we present applications of EIS sensors modified with negatively charged gold nanoparticles for the label-free electrostatic detection of positively charged small proteins and macromolecules, for monitoring the layer-by-layer formation of oppositely charged polyelectrolyte (PE) multilayers as well as for the development of an enzyme-based biomolecular logic gate. In the second part, examples of a label-free detection by means of EIS sensors modified with a positively charged weak PE layer are demonstrated. These include electrical detection of on-chip and in-solution hybridized DNA (deoxyribonucleic acid) as well as an EIS sensor with pH-responsive weak PE/enzyme multilayers for enhanced field-effect biosensing.}, language = {en} } @incollection{TranTranMatthiesetal.2017, author = {Tran, N. T. and Tran, Thanh Ngoc and Matthies, M. G. and Stavroulakis, G. E. and Staat, Manfred}, title = {Shakedown Analysis Under Stochastic Uncertainty by Chance Constrained Programming}, series = {Advances in Direct Methods for Materials and Structures}, booktitle = {Advances in Direct Methods for Materials and Structures}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-59810-9}, doi = {10.1007/978-3-319-59810-9_6}, pages = {85 -- 103}, year = {2017}, abstract = {In this paper we propose a stochastic programming method to analyse limit and shakedown of structures under uncertainty condition of strength. Based on the duality theory, the shakedown load multiplier formulated by the kinematic theorem is proved actually to be the dual form of the shakedown load multiplier formulated by static theorem. In this investigation a dual chance constrained programming algorithm is developed to calculate simultaneously both the upper and lower bounds of the plastic collapse limit and the shakedown limit. The edge-based smoothed finite element method (ES-FEM) with three-node linear triangular elements is used for structural analysis.}, language = {en} } @incollection{NiemuellerZwillingLakemeyeretal.2017, author = {Niemueller, Tim and Zwilling, Frederik and Lakemeyer, Gerhard and L{\"o}bach, Matthias and Reuter, Sebastian and Jeschke, Sabina and Ferrein, Alexander}, title = {Cyber-Physical System Intelligence}, series = {Industrial Internet of Things}, booktitle = {Industrial Internet of Things}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-42559-7}, doi = {10.1007/978-3-319-42559-7_17}, pages = {447 -- 472}, year = {2017}, abstract = {Cyber-physical systems are ever more common in manufacturing industries. Increasing their autonomy has been declared an explicit goal, for example, as part of the Industry 4.0 vision. To achieve this system intelligence, principled and software-driven methods are required to analyze sensing data, make goal-directed decisions, and eventually execute and monitor chosen tasks. In this chapter, we present a number of knowledge-based approaches to these problems and case studies with in-depth evaluation results of several different implementations for groups of autonomous mobile robots performing in-house logistics in a smart factory. We focus on knowledge-based systems because besides providing expressive languages and capable reasoning techniques, they also allow for explaining how a particular sequence of actions came about, for example, in the case of a failure.}, language = {en} } @incollection{NiemuellerLakemeyerReuteretal.2017, author = {Niemueller, T. and Lakemeyer, G. and Reuter, S. and Jeschke, S. and Ferrein, Alexander}, title = {Benchmarking of Cyber-Physical Systems in Industrial Robotics: The RoboCup Logistics League as a CPS Benchmark Blueprint}, series = {Cyber-Physical Systems: Foundations, Principles and Applications}, booktitle = {Cyber-Physical Systems: Foundations, Principles and Applications}, publisher = {Academic Press}, address = {London}, doi = {10.1016/B978-0-12-803801-7.00013-4}, pages = {193 -- 207}, year = {2017}, abstract = {In the future, we expect manufacturing companies to follow a new paradigm that mandates more automation and autonomy in production processes. Such smart factories will offer a variety of production technologies as services that can be combined ad hoc to produce a large number of different product types and variants cost-effectively even in small lot sizes. This is enabled by cyber-physical systems that feature flexible automated planning methods for production scheduling, execution control, and in-factory logistics. During development, testbeds are required to determine the applicability of integrated systems in such scenarios. Furthermore, benchmarks are needed to quantify and compare system performance in these industry-inspired scenarios at a comprehensible and manageable size which is, at the same time, complex enough to yield meaningful results. In this chapter, based on our experience in the RoboCup Logistics League (RCLL) as a specific example, we derive a generic blueprint for how a holistic benchmark can be developed, which combines a specific scenario with a set of key performance indicators as metrics to evaluate the overall integrated system and its components.}, language = {de} } @incollection{Fissabre2018, author = {Fissabre, Anke}, title = {Vom Schiff an Land oder von der Muschel zur Rocaille}, series = {Schwimmender Barock : Das Schiff als Repr{\"a}sentationsobjekt}, booktitle = {Schwimmender Barock : Das Schiff als Repr{\"a}sentationsobjekt}, editor = {Priesterjahn, Maike}, publisher = {Bebra Verlag}, address = {Berlin}, isbn = {978-3-89809-153-4}, pages = {59 -- 65}, year = {2018}, language = {de} } @incollection{YoshinobuKrauseMiyamotoetal.2018, author = {Yoshinobu, Tatsuo and Krause, Steffi and Miyamoto, Ko-ichiro and Werner, Frederik and Poghossian, Arshak and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {(Bio-)chemical Sensing and Imaging by LAPS and SPIM}, series = {Label-free biosensing: advanced materials, devices and applications}, booktitle = {Label-free biosensing: advanced materials, devices and applications}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-75219-8}, pages = {103 -- 132}, year = {2018}, abstract = {The light-addressable potentiometric sensor (LAPS) and scanning photo-induced impedance microscopy (SPIM) are two closely related methods to visualise the distributions of chemical species and impedance, respectively, at the interface between the sensing surface and the sample solution. They both have the same field-effect structure based on a semiconductor, which allows spatially resolved and label-free measurement of chemical species and impedance in the form of a photocurrent signal generated by a scanning light beam. In this article, the principles and various operation modes of LAPS and SPIM, functionalisation of the sensing surface for measuring various species, LAPS-based chemical imaging and high-resolution sensors based on silicon-on-sapphire substrates are described and discussed, focusing on their technical details and prospective applications.}, language = {en} } @incollection{SaldenFischerBarnat2016, author = {Salden, Peter and Fischer, Kathrin and Barnat, Miriam}, title = {Didaktische Studiengangentwicklung: Rahmenkonzepte und Praxisbeispiel}, series = {P{\"a}dagogische Hochschulentwicklung. Von der Programmierung zur Implementierung}, booktitle = {P{\"a}dagogische Hochschulentwicklung. Von der Programmierung zur Implementierung}, publisher = {Springer VS}, address = {Wiesbaden}, isbn = {978-3-658-12067-2}, doi = {10.1007/978-3-658-12067-2_9}, pages = {133 -- 149}, year = {2016}, abstract = {Die Studiengangentwicklung ist ein komplexer Prozess, in dem strukturelle Vorgaben beachtet, viele unterschiedliche Akteure/-innen einbezogen und nicht zuletzt angemessene didaktische L{\"o}sungen zum Erreichen der angestrebten Lernergebnisse gefunden werden m{\"u}ssen. Der vorliegende Text nimmt besonders den letzten Punkt in den Blick: Er zeigt, wie Studiengangentwicklung zu einem Thema der (Hochschul-)Didaktik geworden ist und wie sich der didaktische Ansatz von struktur- und prozessorientierten Ans{\"a}tzen unterscheidet, aber auch, wie er mit diesen zusammenh{\"a}ngt. An einem Beispiel aus dem Wirtschaftsingenieurwesen wird veranschaulicht, was didaktische Studiengangentwicklung in der Praxis ausmacht und wie eine konkrete Implementierung verlaufen kann. Auf dieser Grundlage wird abschließend ein erweitertes Modell der didaktischen Studiengangentwicklung vorgeschlagen.}, language = {de} } @incollection{Barnat2007, author = {Barnat, Miriam}, title = {Organisationale Lernprozesse und Machtquellen. Eine Fallstudie}, series = {Beratung, Macht und organisationales Lernen}, booktitle = {Beratung, Macht und organisationales Lernen}, publisher = {VS Verlag f{\"u}r Sozialwissenschaften}, address = {Wiesbaden}, isbn = {978-3-531-90752-9}, doi = {10.1007/978-3-531-90752-9_7}, pages = {97 -- 110}, year = {2007}, language = {de} } @incollection{BosseBarnat2019, author = {Bosse, Elke and Barnat, Miriam}, title = {Kombination qualitativer und quantitativer Methoden zur Untersuchung der Studieneinstiegsphase}, series = {Hochschulbildungsforschung : Theoretische, methodologische und methodische Denkanst{\"o}ße f{\"u}r die Hochschuldidaktik}, booktitle = {Hochschulbildungsforschung : Theoretische, methodologische und methodische Denkanst{\"o}ße f{\"u}r die Hochschuldidaktik}, publisher = {Springer VS}, address = {Wiesbaden}, isbn = {978-3-658-20309-2}, doi = {10.1007/978-3-658-20309-2_10}, pages = {169 -- 184}, year = {2019}, abstract = {Mit Hilfe der Kombination von qualitativen und quantitativen Verfahren zielen Mixed-Methods Ans{\"a}tze darauf ab, einen vertieften Einblick in komplexe Gegenst{\"a}nde zu gewinnen. In der Hochschulbildungsforschung finden sie zunehmend Anklang, da sie besonders geeignet erscheinen, das vielschichtige Wirkungsgef{\"u}ge zu erfassen, das das Lehren und Lernen an Hochschulen auszeichnet. Der Beitrag geht den Potenzialen von Mixed-Methods Ans{\"a}tzen am Beispiel einer Studie zur Studieneingangsphase nach, die den Wirkungszusammenhang zwischen der Nutzung von Angeboten f{\"u}r den Studieneinstieg und der Entwicklung von Studierf{\"a}higkeit untersucht. Der Beitrag veranschaulicht die Integration von Methoden und Ergebnissen, um Chancen und Grenzen von Mixed-Methods Studien f{\"u}r die Hochschulbildungsforschung zu diskutieren.}, language = {de} } @incollection{KirschBassen2013, author = {Kirsch, Hans-J{\"u}rgen and Bassen, Yasmine}, title = {IGW RS HFA 21 : konzeptionelle L{\"o}sung oder Einzelfall? ; Erfolg bei Spenden sammelnden Organisationen ; eine bilanztheoretische Untersuchung}, series = {Jahrbuch f{\"u}r Controlling und Rechnungswesen. Vol. 29}, booktitle = {Jahrbuch f{\"u}r Controlling und Rechnungswesen. Vol. 29}, publisher = {LexisNexis, ARD Orac}, address = {Wien}, pages = {355 -- 369}, year = {2013}, language = {de} } @incollection{SchoeningWagnerPoghossianetal.2018, author = {Sch{\"o}ning, Michael Josef and Wagner, Torsten and Poghossian, Arshak and Miyamoto, K.I. and Werner, C.F. and Krause, S. and Yoshinobu, T.}, title = {Light-addressable potentiometric sensors for (bio-)chemical sensing and imaging}, series = {Encyclopedia of Interfacial Chemistry: Surface Science and Electrochemistry. Vol. 7}, booktitle = {Encyclopedia of Interfacial Chemistry: Surface Science and Electrochemistry. Vol. 7}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {9780128097397}, pages = {295 -- 308}, year = {2018}, language = {en} } @incollection{Martin2019, author = {Martin, Joachim}, title = {Bemessung von Baukonstruktionen}, series = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, booktitle = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-23127-9}, doi = {10.1007/978-3-658-23127-9_1}, pages = {1 -- 11}, year = {2019}, language = {de} } @incollection{Sparla2019, author = {Sparla, Peter}, title = {Vermessung}, series = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, booktitle = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-23127-9}, doi = {10.1007/978-3-658-23127-9_2}, pages = {13 -- 61}, year = {2019}, language = {de} } @incollection{Ulke2019, author = {Ulke, Bernd}, title = {Der baurechtliche Vertrag}, series = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, booktitle = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-23127-9}, pages = {63 -- 87}, year = {2019}, abstract = {Anhand von kurzen theoretischen Einf{\"u}hrungen werden anhand von Beispielen die wesentlichen Aspekte des baurechtlichen Vertrages erl{\"a}utert. Nach einer Einf{\"u}hrung {\"u}ber das Zustandekommen von (Bau-) Vertr{\"a}gen wird die f{\"u}r Streitf{\"a}lle unerl{\"a}ssliche Dokumentation auf Baustellen erl{\"a}utert. Hierbei werden Hinweise zur Erstellung von Protokollen, zum E-Mail bei Großprojekten und zur Dokumentation von Stundenlohnarbeiten gegeben. Des Weiteren wird eine Schriftverkehrsliste vorgestellt, die zur Nachverfolgung des Schriftverkehrs bei Großprojekten unerl{\"a}sslich ist. Anschließend werden die typischen Vertragsarten vorgestellt, die bei der Abwicklung von Großprojekten zu beachten sind und die Unterschiede werden durch Fallbeispiele erl{\"a}utert. Einen Schwerpunkt des Kapitels bilden auftragsnehmerseitige Verz{\"u}ge sowie mangelbehaftete Leistungen. Hier werden Hinweise gegeben, wie in den entsprechenden Situationen zu reagieren ist.}, language = {de} } @incollection{Ulke2019, author = {Ulke, Bernd}, title = {Baukosten und Finanzierung}, series = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, booktitle = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-23127-9}, doi = {10.1007/978-3-658-23127-9_4}, pages = {89 -- 100}, year = {2019}, language = {de} } @incollection{Krause2019, author = {Krause, Thomas}, title = {Bauabrechnung und Mengenermittlung}, series = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, booktitle = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-23127-9}, doi = {10.1007/978-3-658-23127-9_5}, pages = {101 -- 116}, year = {2019}, language = {de} } @incollection{Ulke2019, author = {Ulke, Bernd}, title = {Arbeitsvorbereitung und Ablaufplanung}, series = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, booktitle = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-23127-9}, doi = {10.1007/978-3-658-23127-9_6}, pages = {117 -- 154}, year = {2019}, language = {de} } @incollection{Krause2019, author = {Krause, Thomas}, title = {Baumaschinen}, series = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, booktitle = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-23127-9}, doi = {10.1007/978-3-658-23127-9_7}, pages = {155 -- 163}, year = {2019}, language = {de} } @incollection{Ulke2019, author = {Ulke, Bernd}, title = {Boden, Baugrube, Verbau}, series = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, booktitle = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-23127-9 (Online)}, doi = {10.1007/978-3-658-23127-9_8}, pages = {165 -- 239}, year = {2019}, abstract = {Im folgenden Kapitel werden die wichtigsten geotechnischen Nachweise sowie praxisnahe Beispiele f{\"u}r den Baubetrieb aufgef{\"u}hrt. Es wird im Wesentlichen auf die Bodenbeschreibung und Klassifikation nach DIN 18196 sowie nach DIN 18300 eingegangen, welche sowohl f{\"u}r die weiteren Berechnungen als auch f{\"u}r die Kalkulation von großer Bedeutung sind. Die aus der Praxis aufgef{\"u}hrten Beispiele verdeutlichen verschiedene Untersuchungs- und Auswertungsmethoden f{\"u}r direkte und indirekte Aufschl{\"u}sse, diese enthalten Labor- und Feldversuche, mit denen man die Verdichtbarkeit von B{\"o}den auswertet und quantifiziert, sowie viele andere Themenbereiche wie Erddruckberechnungen sowie Spannungs- und Setzungsberechnungen. Dar{\"u}ber hinaus werden exemplarisch bestimmte Verbauarten bez{\"u}glich ihrer Bemessung erl{\"a}utert. Es wird ebenfalls auf das Thema Wasserhaltung eingegangen und die erforderlichen Maßnahmen beschrieben, um bestimmte Versagensmechanismen - wie z.B. den hydraulischen Grundbruch - zu verhindern.}, language = {de} } @incollection{Krause2019, author = {Krause, Thomas}, title = {Schalung und Ger{\"u}ste}, series = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, booktitle = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-23127-9 (Online)}, doi = {10.1007/978-3-658-23127-9_9}, pages = {241 -- 253}, year = {2019}, abstract = {Die grunds{\"a}tzliche Planung von Schalungsaufgaben wird heute in der Regel im Rahmen der Arbeitsvorbereitung von den entsprechenden Stabsabteilungen oder als Serviceleistung von den Schalungsherstellern mit Anwendung von spezieller Software und den technischen Unterlagen f{\"u}r die jeweiligen Schalungsger{\"a}te durchgef{\"u}hrt. Diese Programme und technischen Unterlagen stehen in der Regel auch den Mitarbeitern in der Bauleitung zur Verf{\"u}gung, werden dort aber eher seltener genutzt. Zur Anwendung auf der Baustelle stellen die Schalungshersteller neben den technischen Unterlagen Bemessungstabellen zur Verf{\"u}gung, welche die Auswahl und Dimensionierung einzelner Schalungen wesentlich erleichtern. Die nachfolgend aufgef{\"u}hrten Beispiele aus dem Bereich Schalung und Ger{\"u}ste beschreiben Aufgaben, die im Baustellenbetrieb auf die Bauleitung zu kommen k{\"o}nnen und auch ohne Unterst{\"u}tzung einer Stabsabteilung gel{\"o}st werden k{\"o}nnen.}, language = {de} } @incollection{Martin2019, author = {Martin, Joachim}, title = {Betriebsorganisation}, series = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, booktitle = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-23127-9}, doi = {10.1007/978-3-658-23127-9_10}, pages = {255 -- 272}, year = {2019}, language = {de} } @incollection{Streit2019, author = {Streit, Wilfried}, title = {Kalkulation}, series = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, booktitle = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-23127-9}, doi = {10.1007/978-3-658-23127-9_11}, pages = {273 -- 334}, year = {2019}, language = {de} } @incollection{Lemke2019, author = {Lemke, J{\"o}rg}, title = {Arbeitssicherheit}, series = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, booktitle = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-23127-9}, doi = {10.1007/978-3-658-23127-9_12}, pages = {335 -- 344}, year = {2019}, language = {de} } @incollection{Laack2020, author = {Laack, Walter van}, title = {Twee Kanten van {\´e}{\´e}n Medaille}, series = {Het Geheim van Elysion : 45 Jaar Studies naar Nabij-de-Dood-Ervaringen over Bewustzijn in Liefde zonder Waarheen}, booktitle = {Het Geheim van Elysion : 45 Jaar Studies naar Nabij-de-Dood-Ervaringen over Bewustzijn in Liefde zonder Waarheen}, publisher = {Van Warven}, address = {Kampen}, isbn = {978-94-93175-44-0}, pages = {97 -- 105}, year = {2020}, language = {nl} } @incollection{DiekmannEggert2021, author = {Diekmann, Julian and Eggert, Mathias}, title = {Is a Progressive Web App an Alternative for Native App Development?}, series = {3. Wissenschaftsforum: Digitale Transformation (WiFo21) (Lecture Notes in Informatics ; P-319)}, booktitle = {3. Wissenschaftsforum: Digitale Transformation (WiFo21) (Lecture Notes in Informatics ; P-319)}, publisher = {Gesellschaft f{\"u}r Informatik}, address = {Darmstadt}, isbn = {978-3-88579-713-5}, pages = {35 -- 48}, year = {2021}, abstract = {The existence of several mobile operating systems, such as Android and iOS, is a challenge for developers because the individual platforms are not compatible with each other and require separate app developments. For this reason, cross-platform approaches have become popular but lack in cloning the native behavior of the different operating systems. Out of the plenty cross-platform approaches, the progressive web app (PWA) approach is perceived as promising but needs further investigation. Therefore, the paper at hand aims at investigating whether PWAs are a suitable alternative for native apps by developing a PWA clone of an existing app. Two surveys are conducted in which potential users test and evaluate the PWA prototype with regard to its usability. The survey results indicate that PWAs have great potential, but cannot be treated as a general alternative to native apps. For guiding developers when and how to use PWAs, four design guidelines for the development of PWA-based apps are derived based on the results.}, language = {en} } @incollection{Dachwald2010, author = {Dachwald, Bernd}, title = {Solar sail dynamics and control}, series = {Encyclopedia of Aerospace Engineering}, booktitle = {Encyclopedia of Aerospace Engineering}, publisher = {Wiley}, address = {Hoboken}, doi = {10.1002/9780470686652.eae292}, year = {2010}, abstract = {Solar sails are large and lightweight reflective structures that are propelled by solar radiation pressure. This chapter covers their orbital and attitude dynamics and control. First, the advantages and limitations of solar sails are discussed and their history and development status is outlined. Because the dynamics of solar sails is governed by the (thermo-)optical properties of the sail film, the basic solar radiation pressure force models have to be described and compared before parameters to measure solar sail performance can be defined. The next part covers the orbital dynamics of solar sails for heliocentric motion, planetocentric motion, and motion at Lagrangian equilibrium points. Afterwards, some advanced solar radiation pressure force models are described, which allow to quantify the thrust force on solar sails of arbitrary shape, the effects of temperature, of light incidence angle, of surface roughness, and the effects of optical degradation of the sail film in the space environment. The orbital motion of a solar sail is strongly coupled to its rotational motion, so that the attitude control of these soft and flexible structures is very challenging, especially for planetocentric orbits that require fast attitude maneuvers. Finally, some potential attitude control methods are sketched and selection criteria are given.}, language = {en} } @incollection{AkimbekovDigelSherelkhanetal.2022, author = {Akimbekov, Nuraly S. and Digel, Ilya and Sherelkhan, Dinara K. and Razzaque, Mohammed S.}, title = {Vitamin D and Phosphate Interactions in Health and Disease}, series = {Phosphate Metabolism}, booktitle = {Phosphate Metabolism}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-91621-3}, doi = {10.1007/978-3-030-91623-7_5}, pages = {37 -- 46}, year = {2022}, abstract = {Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis, maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as calcitriol (1,25(OH)2D), not only increases intestinal calcium and phosphate absorption but also facilitates their renal reabsorption, leading to elevated serum calcium and phosphate levels. The interaction of 1,25(OH)2D with its receptor (VDR) increases the efficiency of intestinal absorption of calcium to 30-40\% and phosphate to nearly 80\%. Serum phosphate levels can also influence 1,25 (OH)2D and fibroblast growth factor 23 (FGF23) levels, i.e., higher phosphate concentrations suppress vitamin D activation and stimulate parathyroid hormone (PTH) release, while a high FGF23 serum level leads to reduced vitamin D synthesis. In the vitamin D-deficient state, the intestinal calcium absorption decreases and the secretion of PTH increases, which in turn causes the stimulation of 1,25(OH)2D production, resulting in excessive urinary phosphate loss. Maintenance of phosphate homeostasis is essential as hyperphosphatemia is a risk factor of cardiovascular calcification, chronic kidney diseases (CKD), and premature aging, while hypophosphatemia is usually associated with rickets and osteomalacia. This chapter elaborates on the possible interactions between vitamin D and phosphate in health and disease.}, language = {en} } @incollection{EngelmannShashaSlabu2021, author = {Engelmann, Ulrich M. and Shasha, Carolyn and Slabu, Ioana}, title = {Magnetic nanoparticle relaxation in biomedical application: focus on simulating nanoparticle heating}, series = {Magnetic nanoparticles in human health and medicine}, booktitle = {Magnetic nanoparticles in human health and medicine}, publisher = {Wiley-Blackwell}, address = {Hoboken, New Jeersey}, isbn = {978-1-119-75467-1}, pages = {327 -- 354}, year = {2021}, language = {en} } @incollection{HoffschmidtAlexopoulosRauetal.2021, author = {Hoffschmidt, Bernhard and Alexopoulos, Spiros and Rau, Christoph and Sattler, Johannes, Christoph and Anthrakidis, Anette and Teixeira Boura, Cristiano Jos{\´e} and O'Connor, B. and Caminos, R.A. Chico and Rend{\´o}n, C. and Hilger, P.}, title = {Concentrating Solar Power}, series = {Earth systems and environmental sciences}, booktitle = {Earth systems and environmental sciences}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {978-0-12-409548-9}, doi = {10.1016/B978-0-12-819727-1.00089-3}, year = {2021}, abstract = {The focus of this chapter is the production of power and the use of the heat produced from concentrated solar thermal power (CSP) systems. The chapter starts with the general theoretical principles of concentrating systems including the description of the concentration ratio, the energy and mass balance. The power conversion systems is the main part where solar-only operation and the increase in operational hours. Solar-only operation include the use of steam turbines, gas turbines, organic Rankine cycles and solar dishes. The operational hours can be increased with hybridization and with storage. Another important topic is the cogeneration where solar cooling, desalination and of heat usage is described. Many examples of commercial CSP power plants as well as research facilities from the past as well as current installed and in operation are described in detail. The chapter closes with economic and environmental aspects and with the future potential of the development of CSP around the world.}, language = {en} } @incollection{LeiseAltherrSimonetal.2019, author = {Leise, Philipp and Altherr, Lena and Simon, Nicolai and Pelz, Peter F.}, title = {Finding global-optimal gearbox designs for battery electric vehicles}, series = {Optimization of complex systems - theory, models, algorithms and applications : WCGO 2019}, booktitle = {Optimization of complex systems - theory, models, algorithms and applications : WCGO 2019}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-21802-7}, doi = {10.1007/978-3-030-21803-4_91}, pages = {916 -- 925}, year = {2019}, abstract = {In order to maximize the possible travel distance of battery electric vehicles with one battery charge, it is mandatory to adjust all components of the powertrain carefully to each other. While current vehicle designs mostly simplify the powertrain rigorously and use an electric motor in combination with a gearbox with only one fixed transmission ratio, the use of multi-gear systems has great potential. First, a multi-speed system is able to improve the overall energy efficiency. Secondly, it is able to reduce the maximum momentum and therefore to reduce the maximum current provided by the traction battery, which results in a longer battery lifetime. In this paper, we present a systematic way to generate multi-gear gearbox designs that—combined with a certain electric motor—lead to the most efficient fulfillment of predefined load scenarios and are at the same time robust to uncertainties in the load. Therefore, we model the electric motor and the gearbox within a Mixed-Integer Nonlinear Program, and optimize the efficiency of the mechanical parts of the powertrain. By combining this mathematical optimization program with an unsupervised machine learning algorithm, we are able to derive global-optimal gearbox designs for practically relevant momentum and speed requirements.}, language = {en} } @incollection{StengerAltherrAbel2019, author = {Stenger, David and Altherr, Lena and Abel, Dirk}, title = {Machine learning and metaheuristics for black-box optimization of product families: a case-study investigating solution quality vs. computational overhead}, series = {Operations Research Proceedings 2018}, booktitle = {Operations Research Proceedings 2018}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-18499-5 (Print)}, doi = {10.1007/978-3-030-18500-8_47}, pages = {379 -- 385}, year = {2019}, abstract = {In product development, numerous design decisions have to be made. Multi-domain virtual prototyping provides a variety of tools to assess technical feasibility of design options, however often requires substantial computational effort for just a single evaluation. A special challenge is therefore the optimal design of product families, which consist of a group of products derived from a common platform. Finding an optimal platform configuration (stating what is shared and what is individually designed for each product) and an optimal design of all products simultaneously leads to a mixed-integer nonlinear black-box optimization model. We present an optimization approach based on metamodels and a metaheuristic. To increase computational efficiency and solution quality, we compare different types of Gaussian process regression metamodels adapted from the domain of machine learning, and combine them with a genetic algorithm. We illustrate our approach on the example of a product family of electrical drives, and investigate the trade-off between solution quality and computational overhead.}, language = {en} } @incollection{PfetschAbeleAltherretal.2021, author = {Pfetsch, Marc E. and Abele, Eberhard and Altherr, Lena and B{\"o}lling, Christian and Br{\"o}tz, Nicolas and Dietrich, Ingo and Gally, Tristan and Geßner, Felix and Groche, Peter and Hoppe, Florian and Kirchner, Eckhard and Kloberdanz, Hermann and Knoll, Maximilian and Kolvenbach, Philip and Kuttich-Meinlschmidt, Anja and Leise, Philipp and Lorenz, Ulf and Matei, Alexander and Molitor, Dirk A. and Niessen, Pia and Pelz, Peter F. and Rexer, Manuel and Schmitt, Andreas and Schmitt, Johann M. and Schulte, Fiona and Ulbrich, Stefan and Weigold, Matthias}, title = {Strategies for mastering uncertainty}, series = {Mastering uncertainty in mechanical engineering}, booktitle = {Mastering uncertainty in mechanical engineering}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-78353-2}, doi = {10.1007/978-3-030-78354-9_6}, pages = {365 -- 456}, year = {2021}, abstract = {This chapter describes three general strategies to master uncertainty in technical systems: robustness, flexibility and resilience. It builds on the previous chapters about methods to analyse and identify uncertainty and may rely on the availability of technologies for particular systems, such as active components. Robustness aims for the design of technical systems that are insensitive to anticipated uncertainties. Flexibility increases the ability of a system to work under different situations. Resilience extends this characteristic by requiring a given minimal functional performance, even after disturbances or failure of system components, and it may incorporate recovery. The three strategies are described and discussed in turn. Moreover, they are demonstrated on specific technical systems.}, language = {en} }