@article{SchoeningMourzinaSchubertetal.2000,
  author    = {Sch{\"o}ning, Michael Josef and Mourzina, Y. G. and Schubert, J. and Zander, W. and Legin, A. and Vlasov, Y. G. and L{\"u}th, H.},
  title     = {Can pulsed laser deposition serve as an advanced technique in fabricating chemical sensors?},
  series = {Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...]},
  journal   = {Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...]},
  publisher = {MIC, Mikroelektronik Centret},
  address   = {Lyngby, Denmark},
  isbn      = {87-89935-50-0},
  pages     = {615 -- 618},
  year      = {2000},
  language  = {en}
}
@article{RibitschKarlBirnerGruenbergeretal.2010,
  author    = {Ribitsch, D. and Karl, W. and Birner-Gruenberger, R. and Gruber, K. and Eiteljoerg, I. and Remler, P. and Wieland, S. and Siegert, Petra and Maurer, Karl-Heinz and Schwab, H.},
  title     = {C-terminal truncation of a metagenome-derived detergent protease for effective expression in E. coli},
  series = {Journal of biotechnology},
  volume    = {150},
  journal   = {Journal of biotechnology},
  number    = {3},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-4863 (E-Journal); 0168-1656 (Print)},
  doi       = {10.1016/j.jbiotec.2010.09.947},
  pages     = {408 -- 416},
  year      = {2010},
  abstract  = {Recently, a new alkaline protease named HP70 showing highest homology to extracellular serine proteases of Stenotrophomonas maltophilia and Xanthomonas campestris was found in the course of a metagenome screening for detergent proteases (Niehaus et al., submitted for publication). Attempts to efficiently express the enzyme in common expression hosts had failed. This study reports on the realization of overexpression in Escherichia coli after structural modification of HP70. Modelling of HP70 resulted in a two-domain structure, comprising the catalytic domain and a C-terminal domain which includes about 100 amino acids. On the basis of the modelled structure the enzyme was truncated by deletion of most of the C-terminal domain yielding HP70-C477. This structural modification allowed effective expression of active enzyme using E. coli BL21-Gold as the host. Specific activity of HP70-C477 determined with suc-l-Ala-l-Ala-l-Pro-l-Phe-p-nitroanilide as the substrate was 30 ± 5 U/mg compared to 8 ± 1 U/mg of the native enzyme. HP70-C477 was most active at 40 °C and pH 7-11; these conditions are prerequisite for a potential application as detergent enzyme. Determination of kinetic parameters at 40 °C and pH = 9.5 resulted in KM = 0.23 ± 0.01 mM and kcat = 167.5 ± 3.6 s⁻¹. MS-analysis of peptide fragments obtained from incubation of HP70 and HP70-C477 with insulin B indicated that the C-terminal domain influences the cleavage preferences of the enzyme. Washing experiments confirmed the high potential of HP70-C477 as detergent protease.},
  language  = {en}
}
@article{PaczkowskiWeissbeckerSchoeningetal.2011,
  author    = {Paczkowski, Sebastian and Weißbecker, Bernhard and Sch{\"o}ning, Michael Josef and Sch{\"u}tz, Stefan},
  title     = {Biosensors on the Basis of Insect Olfaction},
  series = {Insect biotechnology / Andreas Vilcinskas, ed.},
  journal   = {Insect biotechnology / Andreas Vilcinskas, ed.},
  publisher = {Springer},
  address   = {Dordrecht [u.a.]},
  isbn      = {978-90-481-9640-1},
  pages     = {225 -- 240},
  year      = {2011},
  language  = {en}
}
@article{KeusgenJuengerKrestetal.2003,
  author    = {Keusgen, Michael and J{\"u}nger, Martina and Krest, Ingo and Sch{\"o}ning, Michael Josef},
  title     = {Biosensoric detection of the cysteine sulphoxide alliin},
  series = {Sensors and Actuators B. 95 (2003), H. 1-3},
  journal   = {Sensors and Actuators B. 95 (2003), H. 1-3},
  isbn      = {0925-4005},
  pages     = {297 -- 302},
  year      = {2003},
  language  = {en}
}
@article{KeusgenJuengerSchoening2002,
  author    = {Keusgen, M. and J{\"u}nger, M. and Sch{\"o}ning, Michael Josef},
  title     = {Biosensoric detection of the cysteine sulphoxide alliin},
  series = {Book of abstracts / ed. by J. Saneistr.},
  journal   = {Book of abstracts / ed. by J. Saneistr.},
  publisher = {Czech Technical University, Faculty of Electrical Engineering, Department of Measurement},
  address   = {Prague},
  isbn      = {80-01-02576-4},
  pages     = {1175 -- 1178},
  year      = {2002},
  language  = {en}
}
@article{SchoeningPoghossian2006,
  author    = {Sch{\"o}ning, Michael Josef and Poghossian, Arshak},
  title     = {BioFEDs (field-effect devices) : State-of-the-art and new directions},
  series = {Electroanalysis},
  volume    = {18},
  journal   = {Electroanalysis},
  number    = {19-20},
  issn      = {1521-4109},
  doi       = {10.1002/elan.200603609},
  pages     = {1893 -- 1900},
  year      = {2006},
  language  = {en}
}
@article{SchrothWeissbeckerSchuetzetal.2002,
  author    = {Schroth, P. and Weißbecker, B. and Sch{\"u}tz, S. and Ecken, H. and Yoshinobu, T. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef},
  title     = {Bioelectronic signal processing - intact chemoreceptors coupled to field-effect devices},
  series = {Lecture Notes of the ICB Seminars},
  journal   = {Lecture Notes of the ICB Seminars},
  publisher = {MCB},
  address   = {Warsaw},
  pages     = {28 -- 42},
  year      = {2002},
  language  = {en}
}
@article{SchrothWeissbeckerSchuetzetal.2001,
  author    = {Schroth, P. and Weißbecker, B. and Sch{\"u}tz, S. and Ecken, H. and Yoshinobu, T. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef},
  title     = {Bioelectronic signal processing - intact chemoreceptors coupled to field-effect devices},
  series = {Biocybernetics and Biomedical Engineering. 21 (2001), H. 3},
  journal   = {Biocybernetics and Biomedical Engineering. 21 (2001), H. 3},
  isbn      = {0208-5216},
  pages     = {27 -- 42},
  year      = {2001},
  language  = {en}
}
@article{LuethThustSteffenetal.2000,
  author    = {L{\"u}th, H. and Thust, M. and Steffen, A. and Kordos, P. and Sch{\"o}ning, Michael Josef},
  title     = {Biochemical sensors with structured and porous silicon capacitors},
  series = {Materials Science and Engineering B. 69-70 (2000)},
  journal   = {Materials Science and Engineering B. 69-70 (2000)},
  isbn      = {0921-5107},
  pages     = {104 -- 108},
  year      = {2000},
  language  = {en}
}
@article{KramerHalamkovaPoghossianetal.2013,
  author    = {Kramer, Friederike and Halamkova, Lenka and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Katz, Evgeny and Halamek, Jan},
  title     = {Biocatalytic analysis of biomarkers for forensic identification of ethnicity between Caucasian and African American},
  series = {The analyst. August 2013},
  volume    = {Vol. 138},
  journal   = {The analyst. August 2013},
  publisher = {Royal Society of Chemistry},
  address   = {Cambridge},
  issn      = {1364-5528 (E-Journal); 0003-2654 (Print)},
  pages     = {6251 -- 6257},
  year      = {2013},
  language  = {en}
}