@inproceedings{RajanButenwegDalgueretal.2017, author = {Rajan, S. and Butenweg, Christoph and Dalguer, L. A. and An, J. H. and Renault, P. and Klinkel, S.}, title = {Fragility curves for a three-storey reinforced concrete test structure of the international benchmark SMART 2013}, series = {16th World Conference on Earthquake, 16WCEE 2017 Santiago Chile, January 9th to 13th 2017}, booktitle = {16th World Conference on Earthquake, 16WCEE 2017 Santiago Chile, January 9th to 13th 2017}, publisher = {Chilean Association on Seismology and Earthquake Engineering (ACHISINA)}, year = {2017}, language = {en} } @inproceedings{RajanHoltschoppenDalgueretal.2016, author = {Rajan, Sreelakshmy and Holtschoppen, B. and Dalguer, L. A. and Klinkel, S. and Butenweg, Christoph}, title = {Seismic fragility analysis of a non-conventional reinforced concrete structure considering different uncertainties}, series = {Proceedings of ISMA2016, International Conference on Noise and Vibration Engineering/USD2016, International Conference on Uncertainty in Structural Dynamics, / ISMA 2016, USD 2016}, booktitle = {Proceedings of ISMA2016, International Conference on Noise and Vibration Engineering/USD2016, International Conference on Uncertainty in Structural Dynamics, / ISMA 2016, USD 2016}, editor = {Sas, P.}, publisher = {KU Leuven}, address = {Leuven}, pages = {4213 -- 4225}, year = {2016}, language = {en} } @inproceedings{RajanKubalskiAltayetal.2017, author = {Rajan, Sreelakshmy and Kubalski, Thomas and Altay, Okyay and Dalguer, Luis A and Butenweg, Christoph}, title = {Multi-dimensional fragility analysis of a RC building with components using response surface method}, series = {24th International Conference on Structural Mechanics in Reactor Technology, Busan, Korea, 20-25 August, 2017}, booktitle = {24th International Conference on Structural Mechanics in Reactor Technology, Busan, Korea, 20-25 August, 2017}, publisher = {International Assn for Structural Mechanics in Reactor Technology (IASMiRT)}, address = {Raleigh, USA}, isbn = {9781510856776}, pages = {3126 -- 3135}, year = {2017}, abstract = {Conventional fragility curves describe the vulnerability of the main structure under external hazards. However, in complex structures such as nuclear power plants, the safety or the risk depends also on the components associated with a system. The classical fault tree analysis gives an overall view of the failure and contains several subsystems to the main event, however, the interactions in the subsystems are not well represented. In order to represent the interaction of the components, a method suggested by Cimellaro et al. (2006) using multidimensional performance limit state functions to obtain the system fragility curves is adopted. This approach gives the possibility of deriving the cumulative fragility taking into account the interaction of the response of different components. In this paper, this approach is used to evaluate seismic risk of a representative electrical building infrastructure, including the component, of a nuclear power plant. A simplified model of the structure, with nonlinear material behavior is employed for the analysis in Abaqus©. The input variables considered are the material parameters, boundary conditions and the seismic input. The variability of the seismic input is obtained from selected ground motion time histories of spectrum compatible synthetic ccelerograms. Unlike the usual Monte Carlo methods used for the probabilistic analysis of the structure, a computationally effective response surface method is used. This method reduces the computational effort of the calculations by reducing the required number of samples.}, language = {en} } @inproceedings{RamanJungHorvathetal.2019, author = {Raman, Aravind Hariharan and Jung, Alexander and Horv{\´a}th, Andr{\´a}s and Becker, Nadine and Staat, Manfred}, title = {Modification of a computer model of human stem cell-derived cardiomyocyte electrophysiology based on Patch-Clamp measurements}, series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen}, booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen}, editor = {Staat, Manfred and Erni, Daniel}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-22-6}, doi = {10.17185/duepublico/48750}, pages = {10 -- 11}, year = {2019}, abstract = {Human induced pluripotent stem cells (hiPSCs) have shown to be promising in disease studies and drug screenings [1]. Cardiomyocytes derived from hiPSCs have been extensively investigated using patch-clamping and optical methods to compare their electromechanical behaviour relative to fully matured adult cells. Mathematical models can be used for translating findings on hiPSCCMs to adult cells [2] or to better understand the mechanisms of various ion channels when a drug is applied [3,4]. Paci et al. (2013) [3] developed the first model of hiPSC-CMs, which they later refined based on new data [3]. The model is based on iCells® (Fujifilm Cellular Dynamics, Inc. (FCDI), Madison WI, USA) but major differences among several cell lines and even within a single cell line have been found and motivate an approach for creating sample-specific models. We have developed an optimisation algorithm that parameterises the conductances (in S/F=Siemens/Farad) of the latest Paci et al. model (2018) [5] using current-voltage data obtained in individual patch-clamp experiments derived from an automated patch clamp system (Patchliner, Nanion Technologies GmbH, Munich).}, language = {en} } @inproceedings{RaupachOrlowskyBuettneretal.2006, author = {Raupach, Michael and Orlowsky, Jeannette and B{\"u}ttner, T. and Dilthey, Ulrich and Schleser, Markus}, title = {Epoxy-impregnated textiles in concrete - load bearing capacity and durability}, series = {Textile reinforced concrete : proceedings of the 1. International RILEM Conference, held at the RWTH Aachen, September 6/7, 2006. (RILEM proceedings ; 50)}, booktitle = {Textile reinforced concrete : proceedings of the 1. International RILEM Conference, held at the RWTH Aachen, September 6/7, 2006. (RILEM proceedings ; 50)}, editor = {Hegger, Josef}, publisher = {RILEM Publ.}, address = {Bagneux}, organization = {International Conference on Textile Reinforced Concrete <1, 2006, Aachen>}, isbn = {2-912143-97-7}, pages = {77 -- 88}, year = {2006}, language = {en} } @inproceedings{RauschFriesenAltherretal.2018, author = {Rausch, Lea and Friesen, John and Altherr, Lena and Pelz, Peter F.}, title = {Using mixed-integer programming for the optimal design of water supply networks for slums}, series = {Operations Research Proceedings 2017}, booktitle = {Operations Research Proceedings 2017}, editor = {Kliewer, Natalia and Ehmke, Jan Fabian and Bornd{\"o}rfer, Ralf}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-89919-0 (Print)}, doi = {10.1007/978-3-319-89920-6_68}, pages = {509 -- 516}, year = {2018}, abstract = {The UN sets the goal to ensure access to water and sanitation for all people by 2030. To address this goal, we present a multidisciplinary approach for designing water supply networks for slums in large cities by applying mathematical optimization. The problem is modeled as a mixed-integer linear problem (MILP) aiming to find a network describing the optimal supply infrastructure. To illustrate the approach, we apply it on a small slum cluster in Dhaka, Bangladesh.}, language = {en} } @inproceedings{RauschLeiseEdereretal.2016, author = {Rausch, Lea and Leise, Philipp and Ederer, Thorsten and Altherr, Lena and Pelz, Peter F.}, title = {A comparison of MILP and MINLP solver performance on the example of a drinking water supply system design problem}, series = {ECCOMAS Congress 2016 VII European Congress on Computational Methods in Applied Sciences and Engineering}, booktitle = {ECCOMAS Congress 2016 VII European Congress on Computational Methods in Applied Sciences and Engineering}, editor = {Papadrakakis, M. and Ppadopoulos, V. and Stefanou, G. and Plevris, V.}, isbn = {978-618-82844-0-1}, pages = {8509 -- 8527}, year = {2016}, abstract = {Finding a good system topology with more than a handful of components is a highly non-trivial task. The system needs to be able to fulfil all expected load cases, but at the same time the components should interact in an energy-efficient way. An example for a system design problem is the layout of the drinking water supply of a residential building. It may be reasonable to choose a design of spatially distributed pumps which are connected by pipes in at least two dimensions. This leads to a large variety of possible system topologies. To solve such problems in a reasonable time frame, the nonlinear technical characteristics must be modelled as simple as possible, while still achieving a sufficiently good representation of reality. The aim of this paper is to compare the speed and reliability of a selection of leading mathematical programming solvers on a set of varying model formulations. This gives us empirical evidence on what combinations of model formulations and solver packages are the means of choice with the current state of the art.}, language = {en} } @inproceedings{ReimerBraunBallmann2006, author = {Reimer, Lars and Braun, Carsten and Ballmann, Josef}, title = {Analysis of the static and dynamic aero-structural response of an elastic swept wing model by direct aeroelastic simulation}, series = {ICAS 2006 proceedings : 25th Congress of the International Council of the Aeronautical Sciences ; Hamburg, Germany, 3 - 8 September, 2006 : 25th International Congress of Aeronautical Sciences}, booktitle = {ICAS 2006 proceedings : 25th Congress of the International Council of the Aeronautical Sciences ; Hamburg, Germany, 3 - 8 September, 2006 : 25th International Congress of Aeronautical Sciences}, publisher = {Optimage}, address = {Edinburgh}, organization = {International Council of the Aeronautical Sciences (ICAS)}, isbn = {0-9533991-7-6}, pages = {Paper No. 2006-10.3.3}, year = {2006}, language = {en} } @inproceedings{ReimerBraunChenetal.2007, author = {Reimer, Lars and Braun, Carsten and Chen, B.-H. and Ballmann, Josef}, title = {Computational aeroelastic analysis and design of the HIRENASD wind tunnel wing model and tests}, series = {Proceedings / IFASD 2007, CEAS/AIAA/KTH International Forum on Aeroelasticity and Structural Dynamics : June 18 - 21, 2007, Stockholm, Sweden}, booktitle = {Proceedings / IFASD 2007, CEAS/AIAA/KTH International Forum on Aeroelasticity and Structural Dynamics : June 18 - 21, 2007, Stockholm, Sweden}, publisher = {KTH}, address = {Stockholm}, pages = {1 CD-ROM}, year = {2007}, language = {en} } @inproceedings{ReindlButenwegKubalski2011, author = {Reindl, Lukas and Butenweg, Christoph and Kubalski, Thomas}, title = {Numerical simulation of unreinforced masonry walls subject to dynamic out-of-plane loading}, series = {COMPDYN 2011 : ECCOMAS Thematic Conference ; Proceedings of the 3rd International Conference on Computational Methods in Structural Dynamics and Earthquake Engineering ; 25-28 May, 2011, Corfu, Greece / Eds.: M. Papadrakakis ...}, booktitle = {COMPDYN 2011 : ECCOMAS Thematic Conference ; Proceedings of the 3rd International Conference on Computational Methods in Structural Dynamics and Earthquake Engineering ; 25-28 May, 2011, Corfu, Greece / Eds.: M. Papadrakakis ...}, publisher = {National Technical Univ. of Athens}, address = {Athen}, organization = {COMPDYN <2011, Corfu>}, isbn = {978-960-99994-0-3}, pages = {1 -- 10}, year = {2011}, language = {en} }