@article{RaabKappelKraemeretal.2011,
  author    = {Raab, Monika and Kappel, Sven and Kr{\"a}mer, Andrea and Sanhaji, Mourad and Matthess, Yves and Kurunci-Csacsko, Elisabeth and Calzada-Wack, Julia and Rathkolb, Birgit and Rosman, Jan and Adler, Thure and Busch, Dirk H. and Esposito, Irene and Fuchs, Helmut and Gailus-Durner, Val{\´e}rie and Klingenspor, Martin and Wolf, Eckhard and S{\"a}nger, Nicole and Prinz, Florian and Hrabe de Angelis, Martin and Seibler, Jost and Yuan, Juping and Bergmann, Martin and Knecht, Rainald and Kreft, Bertolt and Strebhardt, Klaus},
  title     = {Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells},
  series = {Nature Communications},
  volume    = {2},
  journal   = {Nature Communications},
  number    = {395},
  publisher = {Nature},
  address   = {London},
  issn      = {2041-1723},
  doi       = {10.1038/ncomms1395},
  pages     = {1 -- 11},
  year      = {2011},
  language  = {en}
}
@article{HasegawaKapelyukhTaharaetal.2011,
  author    = {Hasegawa, Maki and Kapelyukh, Yury and Tahara, Harunobu and Seibler, Jost and Rode, Anja and Krueger, Sylvia and Lee, Dongtao N. and Wolf, C. Roland and Scheer, Nico},
  title     = {Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line},
  series = {Molecular Pharmacology},
  volume    = {80},
  journal   = {Molecular Pharmacology},
  number    = {33},
  publisher = {ASPET},
  address   = {Bethesda, Md.},
  issn      = {1521-0111},
  doi       = {10.1124/mol.111.071845},
  pages     = {518 -- 528},
  year      = {2011},
  language  = {en}
}
@article{JordanKruegerWillmesetal.2011,
  author    = {Jordan, Sabine D. and Kr{\"u}ger, Markus and Willmes, Diana M. and Redemann, Nora and Wunderlich, F. Thomas and Br{\"o}nneke, Hella S. and Merkwirth, Carsten and Kashkar, Hamid and Olkkonen, Vesa M. and B{\"o}ttger, Thomas and Braun, Thomas and Seibler, Jost and Br{\"u}ning, Jens C.},
  title     = {Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism},
  series = {Nature Cell Biology},
  volume    = {13},
  journal   = {Nature Cell Biology},
  number    = {4},
  publisher = {Nature},
  address   = {New York},
  issn      = {1465-7392},
  doi       = {10.1038/ncb2211},
  pages     = {434 -- 446},
  year      = {2011},
  abstract  = {The contribution of altered post-transcriptional gene silencing to the development of insulin resistance and type 2 diabetes mellitus so far remains elusive. Here, we demonstrate that expression of microRNA (miR)-143 and 145 is upregulated in the liver of genetic and dietary mouse models of obesity. Induced transgenic overexpression of miR-143, but not miR-145, impairs insulin-stimulated AKT activation and glucose homeostasis. Conversely, mice deficient for the miR-143-145 cluster are protected from the development of obesity-associated insulin resistance. Quantitative-mass-spectrometry-based analysis of hepatic protein expression in miR-143-overexpressing mice revealed miR-143-dependent downregulation of oxysterol-binding-protein-related protein (ORP) 8. Reduced ORP8 expression in cultured liver cells impairs the ability of insulin to induce AKT activation, revealing an ORP8-dependent mechanism of AKT regulation. Our experiments provide direct evidence that dysregulated post-transcriptional gene silencing contributes to the development of obesity-induced insulin resistance, and characterize the miR-143-ORP8 pathway as a potential target for the treatment of obesity-associated diabetes.},
  language  = {en}
}
@article{InagakiSleddensLinkelsWassenaaretal.2011,
  author    = {Inagaki, Akiko and Sleddens-Linkels, Esther and Wassenaar, Evelyne and Ooms, Marja and Cappellen, Wiggert A. van and Hoeijmakers, Jan H. J. and Seibler, Jost and Vogt, Thomas F. and Shin, Myung K. and Grootegoed, J. Anton and Baarends, Willy M.},
  title     = {Meiotic functions of RAD18},
  series = {Journal of Cell Science},
  volume    = {124},
  journal   = {Journal of Cell Science},
  number    = {16},
  publisher = {Company of Biologists Limited},
  address   = {Cambridge},
  issn      = {1477-9137},
  doi       = {10.1242/jcs.081968},
  pages     = {2837 -- 2850},
  year      = {2011},
  language  = {en}
}
@article{Fissabre2011,
  author    = {Fissabre, Anke},
  title     = {Dachterrassen der Renaissance - „Cosa pi{\`u} maravigliosa che gl'orti pensili di Babbilonia"},
  series = {Architectura : Zeitschrift f{\"u}r Geschichte der Baukunst},
  volume    = {41},
  journal   = {Architectura : Zeitschrift f{\"u}r Geschichte der Baukunst},
  number    = {1},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {0044-863X},
  pages     = {27 -- 46},
  year      = {2011},
  language  = {de}
}
@article{MottaghyPechnigVogt2011,
  author    = {Mottaghy, Darius and Pechnig, Renate and Vogt, Christian},
  title     = {The geothermal project Den Haag: 3D numerical models for temperature prediction and reservoir simulation},
  series = {Geothermics},
  volume    = {40},
  journal   = {Geothermics},
  number    = {3},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0375-6505},
  doi       = {10.1016/j.geothermics.2011.07.001},
  pages     = {199 -- 210},
  year      = {2011},
  abstract  = {The proposed Den Haag Zuidwest district heating system of the city of The Hague consists of a deep doublet in a Jurassic sandstone layer that is designed for a production temperature of 75 °C and a reinjection temperature of 40 °C at a flow rate of 150 m3 h-1. The prediction of reservoir temperature and production behavior is crucial for success of the proposed geothermal doublet. This work presents the results of a study of the important geothermal and geohydrological issues for the doublet design. In the first phase of the study, the influences of the three-dimensional (3D) structures of anticlines and synclines on the temperature field were examined. A comprehensive petrophysical investigation was performed to build a large scale 3D-model of the reservoir. Several bottomhole temperatures (BHTs), as well as petrophysical logs were used to calibrate the model using thermal conductivity measurements on 50 samples from boreholes in different lithological units in the study area. Profiles and cross sections extracted from the calculated temperature field were used to study the temperature in the surrounding areas of the planned doublet. In the second phase of the project, a detailed 3D numerical reservoir model was set up, with the aim of predicting the evolution of the producer and injector temperatures, and the extent of the cooled area around the injector. The temperature model from the first phase provided the boundary conditions for the reservoir model. Hydraulic parameters for the target horizons, such as porosity and permeability, were taken from data available from the nearby exploration wells. The simulation results are encouraging as no significant thermal breakthrough is predicted. For the originally planned location of the producer, the extracted water temperature is predicted to be around 79 °C, with an almost negligible cooling in the first 50 years of production. When the producer is located shallower parts of the reservoir, the yield water temperatures is lower, starting at ≈76 °C and decreasing to ≈74 °C after 50 years of operation. This comparatively larger decrease in temperature with time is caused by the structural feature of the reservoir, namely a higher dip causes the cooler water to easily move downward. In view of the poor reservoir data, the reservoir simulation model is constructed to allow iterative updates using data assimilation during planned drilling, testing, and production phases. Measurements during an 8 h pumping test carried out in late 2010 suggest that a flow rate of 150 m3 h-1 is achievable. Fluid temperatures of 76.5 °C were measured, which is very close to the predicted value.},
  language  = {en}
}
@article{Lind2011,
  author    = {Lind, Thorsten Patric},
  title     = {Handelndenhaftung bei Vorrats- oder Mantel-GmbH nur f{\"u}r vor Offenlegung der wirtschaftlichen Neugr{\"u}ndung ohne Zustimmung aller Gesellschafter vorgenommene Gesch{\"a}fte : BGH, Urteil vom 12.07.2011 - II ZR 71/11 : Anmerkung},
  series = {Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-M{\"o}hring},
  journal   = {Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-M{\"o}hring},
  number    = {11},
  publisher = {Beck},
  address   = {M{\"u}nchen},
  issn      = {1611-1095},
  pages     = {324602},
  year      = {2011},
  language  = {de}
}
@article{Lind2011,
  author    = {Lind, Thorsten Patric},
  title     = {Keine Beseitigung der Zahlungsunf{\"a}higkeit und ihrer Kenntnis durch Patronatserkl{\"a}rung : BGH, Urteil vom 19.05.2011 - IX ZR 9/10 : Anmerkung},
  series = {Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-M{\"o}hring},
  journal   = {Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-M{\"o}hring},
  number    = {Ausg. 8},
  publisher = {Beck},
  address   = {M{\"u}nchen},
  issn      = {1611-1095},
  pages     = {320922},
  year      = {2011},
  language  = {de}
}
@article{HageLind2011,
  author    = {Hage, Ralf and Lind, Thorsten Patric},
  title     = {Zur Qualifizierung der von dem Aussonderungsberechtigten aufgewandten Ausbaukosten als Masseverbindlichkeiten},
  series = {Zeitschrift f{\"u}r das gesamte Insolvenzrecht : ZInsO},
  journal   = {Zeitschrift f{\"u}r das gesamte Insolvenzrecht : ZInsO},
  number    = {50},
  publisher = {Carl Heymanns Verlag},
  address   = {K{\"o}ln},
  issn      = {1615-8032},
  pages     = {2264 -- 2268},
  year      = {2011},
  language  = {de}
}
@article{NordaButenweg2011,
  author    = {Norda, Hannah and Butenweg, Christoph},
  title     = {M{\"o}glichkeiten und Grenzen der Anwendbarkeit statisch nichtlinearer Verfahren nach DIN EN 1998-1},
  series = {Bauingenieur : die richtungsweisende Zeitschrift im Bauingenieurswesen ; offizielle Zeitschrift der VDI-Gesellschaft Bautechnik. Beilage: D-A-CH-Mitteilungsblatt},
  volume    = {Band 86},
  journal   = {Bauingenieur : die richtungsweisende Zeitschrift im Bauingenieurswesen ; offizielle Zeitschrift der VDI-Gesellschaft Bautechnik. Beilage: D-A-CH-Mitteilungsblatt},
  publisher = {VDI Fachmedien},
  address   = {D{\"u}sseldorf},
  issn      = {1436-4867 (E-Journal); 0005-6650 (Print)},
  pages     = {S13 -- S21},
  year      = {2011},
  language  = {de}
}