@article{HenkenOosterhuisOehlschlaegeretal.2012,
  author    = {Henken, F. E. and Oosterhuis, K. and {\"O}hlschl{\"a}ger, Peter and Bosch, L. and Hooijberg, E. and Haanen, J. B. A. G. and Steenbergen, R. D. M.},
  title     = {Preclinical safety evaluation of DNA vaccines encoding modified HPV16 E6 and E7},
  series = {Vaccine},
  volume    = {30},
  journal   = {Vaccine},
  number    = {28},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0264-410X},
  doi       = {10.1016/j.vaccine.2012.04.013},
  pages     = {4259 -- 4266},
  year      = {2012},
  abstract  = {Persistent infection with high-risk human papillomaviruses (hrHPV) can result in the formation of anogenital cancers. As hrHPV proteins E6 and E7 are required for cancer initiation and maintenance, they are ideal targets for immunotherapeutic interventions. Previously, we have described the development of DNA vaccines for the induction of HPV16 E6 and E7 specific T cell immunity. These vaccines consist of 'gene-shuffled' (SH) versions of HPV16 E6 and E7 that were fused to Tetanus Toxin Fragment C domain 1 (TTFC) and were named TTFC-E6SH and TTFC-E7SH. Gene-shuffling was performed to avoid the risk of inducing malignant transformation at the vaccination site. Here, we describe the preclinical safety evaluation of these candidate vaccines by analysis of their transforming capacity in vitro using established murine fibroblasts (NIH 3T3 cells) and primary human foreskin keratinocytes (HFKs). We demonstrate that neither ectopic expression of TTFC-E6SH and TTFC-E7SH alone or in combination enabled NIH 3T3 cells to form colonies in soft agar. In contrast, expression of HPV16 E6WT and E7WT alone or in combination resulted in effective transformation. Similarly, retroviral transduction of HFKs from three independent donors with both TTFC-E6SH and TTFC-E7SH alone or in combination did not show any signs of immortalization. In contrast, the combined expression of E6WT and E7WT induced immortalization in HFKs from all donors. Based on these results we consider it justified to proceed to clinical evaluation of DNA vaccines encoding TTFC-E6SH and TTFC-E7SH in patients with HPV16 associated (pre)malignancies.},
  language  = {en}
}
@article{ImmelGruetzkeSpaeteetal.2012,
  author    = {Immel, Timo and Gr{\"u}tzke, Martin and Sp{\"a}te, Anne-Katrin and Groth, Ulrich and {\"O}hlschl{\"a}ger, Peter and Huhn, Thomas},
  title     = {Synthesis and X-ray structure analysis of a heptacoordinate titanium(IV)-bis-chelate with enhanced in vivo antitumor efficacy},
  series = {Chemical Communications},
  volume    = {48},
  journal   = {Chemical Communications},
  number    = {46},
  publisher = {Royal Society of Chemistry},
  address   = {Cambridge},
  issn      = {1364-548X},
  doi       = {10.1039/C2CC31624B},
  pages     = {5790 -- 5792},
  year      = {2012},
  abstract  = {Chelate stabilization of a titanium(IV)-salan alkoxide by ligand exchange with 2,6-pyridinedicarboxylic acid (dipic) resulted in heptacoordinate complex 3 which is not redox-active, stable on silica gel and has increased aqueous stability. 3 is highly toxic in HeLa S3 and Hep G2 and has enhanced antitumor efficacy in a mouse cervical-cancer model.},
  language  = {en}
}
@book{Vismann2012,
  author    = {Vismann, Ulrich},
  title     = {Wendehorst Beispiele aus der Baupraxis / Ulrich Vismann (Hrsg.). - 4., durchges. und aktualis. Aufl.},
  publisher = {Springer Vieweg},
  address   = {Wiesbaden},
  isbn      = {978-3-8348-0999-5 ; 978-3-8348-8229-5},
  doi       = {10.1007/978-3-8348-8229-5},
  pages     = {X, 653 S.},
  year      = {2012},
  language  = {de}
}
@inproceedings{HoffschmidtAlexopoulos2012,
  author    = {Hoffschmidt, Bernhard and Alexopoulos, Spiros},
  title     = {Perspektiven f{\"u}r Solarthermische Kraftwerke im Sonneng{\"u}rtel},
  series = {Energiewende : Aspekte, Optionen, Herausforderungen : Vortr{\"a}ge auf der DPG-Fr{\"u}hjahrstagung Arbeitskreis Energie in der Deutschen Physikalischen Gesellschaft Berlin, 26. bis 28. M{\"a}rz 2012 / hrsg. von Hardo Bruhns},
  booktitle = {Energiewende : Aspekte, Optionen, Herausforderungen : Vortr{\"a}ge auf der DPG-Fr{\"u}hjahrstagung Arbeitskreis Energie in der Deutschen Physikalischen Gesellschaft Berlin, 26. bis 28. M{\"a}rz 2012 / hrsg. von Hardo Bruhns},
  publisher = {DPG},
  address   = {Baf Honnef},
  pages     = {81 -- 93},
  year      = {2012},
  language  = {de}
}
@techreport{ButenwegDargelHoechstetal.2012,
  author    = {Butenweg, Christoph and Dargel, H.-J. and H{\"o}chst, T. and Holtschoppen, B. and Schwarz, R. and Sippel, M.},
  title     = {Der Lastfall Erdbeben im Anlagenbau : Leitfaden : Entwurf, Bemessung und Konstruktion von Tragwerken und Komponenten in der chemischen Industrie in Anlehnung an die DIN EN 1998-1},
  publisher = {Verband der Chemischen Industrie e.V.},
  address   = {Frankfurt},
  pages     = {20 S.},
  year      = {2012},
  language  = {de}
}
@inproceedings{Bung2012,
  author    = {Bung, Daniel Bernhard},
  title     = {Sensitivity of phase detection techniques in aerated chute flows to hydraulic design parameters},
  series = {2nd European IAHR congress : 27. - 29. June 2012, M{\"u}nchen},
  booktitle = {2nd European IAHR congress : 27. - 29. June 2012, M{\"u}nchen},
  publisher = {Lehrstuhl u. Versuchsanst. f{\"u}r Wasserbau u. Wasserwirtschaft d. TU M{\"u}nchen},
  address   = {M{\"u}nchen},
  organization    = {International Association for Hydraulic Engineering and Research},
  isbn      = {978-3-943683-03-5},
  pages     = {Artikelkennnummer: B15},
  year      = {2012},
  language  = {en}
}
@inproceedings{FrickeZiolkoAnthrakidisetal.2012,
  author    = {Fricke, Barbara and Ziolko, C. and Anthrakidis, Anette and Alexopoulos, Spiros and Hoffschmidt, Bernhard and Giese, F. and Dillig, M.},
  title     = {InnoSol - environmental aspects of the open volumetric receiver technology},
  series = {30th ISES Biennial Solar World Congress 2011 : : Kassel, Germany, 28 August - 2 September 2011. Vol. 5},
  booktitle = {30th ISES Biennial Solar World Congress 2011 : : Kassel, Germany, 28 August - 2 September 2011. Vol. 5},
  publisher = {Curran},
  address   = {Red Hook, NY},
  organization    = {International Solar Energy Society},
  pages     = {3895 -- 3900},
  year      = {2012},
  language  = {en}
}
@book{Bialonski2012,
  author    = {Bialonski, Stephan},
  title     = {Inferring complex networks from time series of dynamical systems: Pitfalls, misinterpretations, and possible solutions},
  publisher = {Universit{\"a}ts- und Landesbibliothek Bonn},
  address   = {Bonn},
  pages     = {Online-Ausgabe (III, 135 S. : Ill., graph. Darst.)},
  year      = {2012},
  language  = {en}
}
@article{BackesAdamGottschaldetal.2012,
  author    = {Backes, Klaus and Adam, Mario and Gottschald, Beng Jonas and Faber, Christian and Henneb{\"o}hl, Friedrich-Gregor and Lanz, Marco and Anthrakidis, Anette},
  title     = {KWKK-Anlagen im Feldtest. Optimaler Betrieb durch Verbesserungen bei Regelung und Hydraulik},
  series = {Die K{\"a}lte- und Klimatechnik},
  journal   = {Die K{\"a}lte- und Klimatechnik},
  number    = {2},
  publisher = {Gentner},
  address   = {Stuttgart},
  issn      = {0343-2246},
  year      = {2012},
  language  = {de}
}
@inproceedings{SauerbornKlimekHoffschmidtetal.2012,
  author    = {Sauerborn, Markus and Klimek, J. and Hoffschmidt, Bernhard and Essen, H. and Sieger, S. and Biegel, G. and G{\"o}ttsche, Joachim and Hilger, Patrick},
  title     = {Eurosun 2012 : radar technology for heliostat posititon control},
  series = {Eurosun 2012 : Solar energy for a brighter future : conference proceedings : Rijeka, 18.-22.09.2012},
  booktitle = {Eurosun 2012 : Solar energy for a brighter future : conference proceedings : Rijeka, 18.-22.09.2012},
  address   = {Rijeka},
  pages     = {ID 80},
  year      = {2012},
  language  = {en}
}