@incollection{WeberBomholtButenweg2022, author = {Weber, Felix and Bomholt, Frederik and Butenweg, Christoph}, title = {Erdbeben- und Schwingungsschutz von Bauwerken}, series = {2023 BetonKalender: Wasserundurchl{\"a}ssiger Beton, Br{\"u}ckenbau}, booktitle = {2023 BetonKalender: Wasserundurchl{\"a}ssiger Beton, Br{\"u}ckenbau}, editor = {Bergmeister, Konrad and Fingerloos, Frank and W{\"o}rner, Johann-Dietrich}, publisher = {Ernst \& Sohn}, address = {Berlin}, isbn = {9783433611180}, doi = {10.1002/9783433611180.ch16}, pages = {779 -- 859}, year = {2022}, abstract = {Dieser Beitrag beschreibt die herk{\"o}mmlichen Maßnahmen wie die Kapazit{\"a}tsbemessung der Tragwerksstruktur, die Isolation des Bauwerks mittels Basisisolatoren, die D{\"a}mpfungserh{\"o}hung der Struktur mittels Inter-Story-D{\"a}mpfern und die Schwingungsreduktion mittels Schwingungstilgern gegen Einwirkungen durch Erdbeben, Wind, Verkehr und Personen auf die Bauwerke. Erg{\"a}nzend wird die erdbebengerechte Auslegung und Isolation von nichttragenden Bauteilen behandelt. F{\"u}r die betrachteten Systeme werden die Bewegungsdifferenzialgleichungen unter Ber{\"u}cksichtigung der wesentlichen Nichtlinearit{\"a}ten angegeben. Die vorgestellten Weiterentwicklungen in den Bereichen der Basisisolatoren, D{\"a}mpfern und Schwingungstilgern zeigen, dass das modellbasierte Design mittels Simulation ein sehr effektives, {\"o}konomisches und dank der heutigen Computerleistung auch zeiteffizientes Werkzeug darstellt.}, language = {de} } @inproceedings{EggertKriska2022, author = {Eggert, Mathias and Kriska, Melina}, title = {Gamification for software development processes - relevant affordances and design principles}, series = {Proceedings of the 55th Hawaii International Conference on System Sciences}, booktitle = {Proceedings of the 55th Hawaii International Conference on System Sciences}, publisher = {HICSS Publishing}, address = {Honolulu}, isbn = {978-0-9981331-5-7}, doi = {10.24251/HICSS.2022.200}, pages = {1614 -- 1623}, year = {2022}, abstract = {A Gamified Information System (GIS) implements game concepts and elements, such as affordances and game design principles to motivate people. Based on the idea to develop a GIS to increase the motivation of software developers to perform software quality tasks, the research work at hand aims at investigating relevant requirements from that target group. Therefore, 14 interviews with software development experts are conducted and analyzed. According to the results, software developers prefer the affordances points, narrative storytelling in a multiplayer and a round-based setting. Furthermore, six design principles for the development of a GIS are derived.}, language = {en} } @article{HeinEubanksLingametal.2022, author = {Hein, Andreas M. and Eubanks, T. Marshall and Lingam, Manasvi and Hibberd, Adam and Fries, Dan and Schneider, Jean and Kervella, Pierre and Kennedy, Robert and Perakis, Nikolaos and Dachwald, Bernd}, title = {Interstellar now! Missions to explore nearby interstellar objects}, series = {Advances in Space Research}, volume = {69}, journal = {Advances in Space Research}, number = {1}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0273-1177}, doi = {10.1016/j.asr.2021.06.052}, pages = {402 -- 414}, year = {2022}, abstract = {The recently discovered first hyperbolic objects passing through the Solar System, 1I/'Oumuamua and 2I/Borisov, have raised the question about near term missions to Interstellar Objects. In situ spacecraft exploration of these objects will allow the direct determination of both their structure and their chemical and isotopic composition, enabling an entirely new way of studying small bodies from outside our solar system. In this paper, we map various Interstellar Object classes to mission types, demonstrating that missions to a range of Interstellar Object classes are feasible, using existing or near-term technology. We describe flyby, rendezvous and sample return missions to interstellar objects, showing various ways to explore these bodies characterizing their surface, dynamics, structure and composition. Their direct exploration will constrain their formation and history, situating them within the dynamical and chemical evolution of the Galaxy. These mission types also provide the opportunity to explore solar system bodies and perform measurements in the far outer solar system.}, language = {en} } @incollection{AkimbekovDigelSherelkhanetal.2022, author = {Akimbekov, Nuraly S. and Digel, Ilya and Sherelkhan, Dinara K. and Razzaque, Mohammed S.}, title = {Vitamin D and Phosphate Interactions in Health and Disease}, series = {Phosphate Metabolism}, booktitle = {Phosphate Metabolism}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-91621-3}, doi = {10.1007/978-3-030-91623-7_5}, pages = {37 -- 46}, year = {2022}, abstract = {Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis, maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as calcitriol (1,25(OH)2D), not only increases intestinal calcium and phosphate absorption but also facilitates their renal reabsorption, leading to elevated serum calcium and phosphate levels. The interaction of 1,25(OH)2D with its receptor (VDR) increases the efficiency of intestinal absorption of calcium to 30-40\% and phosphate to nearly 80\%. Serum phosphate levels can also influence 1,25 (OH)2D and fibroblast growth factor 23 (FGF23) levels, i.e., higher phosphate concentrations suppress vitamin D activation and stimulate parathyroid hormone (PTH) release, while a high FGF23 serum level leads to reduced vitamin D synthesis. In the vitamin D-deficient state, the intestinal calcium absorption decreases and the secretion of PTH increases, which in turn causes the stimulation of 1,25(OH)2D production, resulting in excessive urinary phosphate loss. Maintenance of phosphate homeostasis is essential as hyperphosphatemia is a risk factor of cardiovascular calcification, chronic kidney diseases (CKD), and premature aging, while hypophosphatemia is usually associated with rickets and osteomalacia. This chapter elaborates on the possible interactions between vitamin D and phosphate in health and disease.}, language = {en} } @inproceedings{ZaehlBiewendtWolfetal.2022, author = {Z{\"a}hl, Philipp M. and Biewendt, Marcel and Wolf, Martin R. and Eggert, Mathias}, title = {Requirements for competence developing games in the environment of SE Competence Development}, series = {AKWI-Tagungsband zur 35. AKWI-Jahrestagung}, booktitle = {AKWI-Tagungsband zur 35. AKWI-Jahrestagung}, publisher = {GITO}, address = {Berlin}, isbn = {978-3-95545-409-8}, doi = {10.30844/AKWI_2022_05}, pages = {73 -- 88}, year = {2022}, abstract = {Many of today's factors make software development more and more complex, such as time pressure, new technologies, IT security risks, et cetera. Thus, a good preparation of current as well as future software developers in terms of a good software engineering education becomes progressively important. As current research shows, Competence Developing Games (CDGs) and Serious Games can offer a potential solution. This paper identifies the necessary requirements for CDGs to be conducive in principle, but especially in software engineering (SE) education. For this purpose, the current state of research was summarized in the context of a literature review. Afterwards, some of the identified requirements as well as some additional requirements were evaluated by a survey in terms of subjective relevance.}, language = {en} } @article{KubalskiButenwegElDeib2022, author = {Kubalski, Thomas and Butenweg, Christoph and El-Deib, Khaled}, title = {Vereinfachte Ber{\"u}cksichtigung der Rahmentragwirkung in Mauerwerksgeb{\"a}uden}, series = {Bautechnik}, volume = {99}, journal = {Bautechnik}, number = {12}, editor = {Jesse, Dirk}, publisher = {Ernst \& Sohn}, address = {Berlin}, issn = {0932-8351}, doi = {10.1002/bate.202200081}, pages = {865 -- 928}, year = {2022}, abstract = {Aufgrund der gestiegenen Anforderungen durch h{\"o}here Ein-wirkungen aus Wind und Erdbeben ist eine Verbesserung und Optimierung der Berechnungs- und Bemessungsans{\"a}tze f{\"u}r Mauerwerksbauten erforderlich. Eine bessere Ausnutzung der Tragwerksreserven ist durch die Ber{\"u}cksichtigung der Rah-mentragwirkung mit einer Aktivierung der Deckenscheiben in den Rechenmodellen m{\"o}glich, die in der Praxis aufgrund der Komplexit{\"a}t der Wand-Decken-Interaktion bislang nicht aus-genutzt wird. Im vorliegenden Aufsatz wird ein vereinfachter Ansatz auf Grundlage der mitwirkenden Plattenbreite von Schubw{\"a}nden aus Mauerwerk vorgestellt, der die wesentli-chen Einfl ussfaktoren in parametrisierten Tabellen erfasst. Damit steht den Tragwerksplanern ein einfach anwendbares Werkzeug zur Verf{\"u}gung, um die Rahmentragwirkung in der Mauerwerksbemessung anzusetzen.}, language = {de} } @inproceedings{WeissHeslenfeldSaeweetal.2022, author = {Weiss, Christian and Heslenfeld, Jonas and Saewe, Jasmin Kathrin and Bremen, Sebastian and H{\"a}fner, Constantin Leon}, title = {Investigation on the influence of powder humidity in Laser Powder Bed Fusion (LPBF)}, series = {Procedia CIRP 12th CIRP Conference on Photonic Technologies [LANE 2022]}, volume = {111}, booktitle = {Procedia CIRP 12th CIRP Conference on Photonic Technologies [LANE 2022]}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2212-8271}, doi = {10.1016/j.procir.2022.08.102}, pages = {115 -- 120}, year = {2022}, abstract = {In the Laser Powder Bed Fusion (LPBF) process, parts are built out of metal powder material by exposure of a laser beam. During handling operations of the powder material, several influencing factors can affect the properties of the powder material and therefore directly influence the processability during manufacturing. Contamination by moisture due to handling operations is one of the most critical aspects of powder quality. In order to investigate the influences of powder humidity on LPBF processing, four materials (AlSi10Mg, Ti6Al4V, 316L and IN718) are chosen for this study. The powder material is artificially humidified, subsequently characterized, manufactured into cubic samples in a miniaturized process chamber and analyzed for their relative density. The results indicate that the processability and reproducibility of parts made of AlSi10Mg and Ti6Al4V are susceptible to humidity, while IN718 and 316L are barely influenced.}, language = {en} } @inproceedings{EggertDyong2022, author = {Eggert, Mathias and Dyong, Julian}, title = {Applying process mining in small and medium sized IT enterprises - challenges and guidelines}, series = {Business Process Management, 20th International Conference, BPM 2022, Proceedings}, booktitle = {Business Process Management, 20th International Conference, BPM 2022, Proceedings}, publisher = {Springer}, address = {Cham}, isbn = {978-3-031-16103-2}, doi = {10.1007/978-3-031-16103-2_11}, pages = {125 -- 142}, year = {2022}, abstract = {Process mining gets more and more attention even outside large enterprises and can be a major benefit for small and medium sized enterprises (SMEs) to gain competitive advantages. Applying process mining is challenging, particularly for SMEs because they have less resources and process maturity. So far, IS researchers analyzed process mining challenges with a focus on larger companies. This paper investigates the application of process mining by means of a case study and sheds light into the particular challenges of an IT SME. The results reveal 13 SME process mining challenges and seven guidelines to address them. In this way, the paper contributes to the understanding of process mining application in SME and shows similarities and differences to larger companies.}, language = {en} } @article{vonHaefenKrautwaldStolleetal.2022, author = {von H{\"a}fen, Hajo and Krautwald, Clemens and Stolle, Jacob and Bung, Daniel Bernhard and Goseberg, Nils}, title = {Overland flow of broken solitary waves over a two-dimensional coastal plane}, series = {Coastal Engineering}, volume = {175}, journal = {Coastal Engineering}, number = {August}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1872-7379}, doi = {10.1016/j.coastaleng.2022.104125}, pages = {14 Seiten}, year = {2022}, abstract = {Landslides, rock falls or related subaerial and subaqueous mass slides can generate devastating impulse waves in adjacent waterbodies. Such waves can occur in lakes and fjords, or due to glacier calving in bays or at steep ocean coastlines. Infrastructure and residential houses along coastlines of those waterbodies are often situated on low elevation terrain, and are potentially at risk from inundation. Impulse waves, running up a uniform slope and generating an overland flow over an initially dry adjacent horizontal plane, represent a frequently found scenario, which needs to be better understood for disaster planning and mitigation. This study presents a novel set of large-scale flume test focusing on solitary waves propagating over a 1:14.5 slope and breaking onto a horizontal section. Examining the characteristics of overland flow, this study gives, for the first time, insight into the fundamental process of overland flow of a broken solitary wave: its shape and celerity, as well as its momentum when wave breaking has taken place beforehand.}, language = {en} } @article{FalkenbergRahbaFischeretal.2022, author = {Falkenberg, Fabian and Rahba, Jade and Fischer, David and Bott, Michael and Bongaerts, Johannes and Siegert, Petra}, title = {Biochemical characterization of a novel oxidatively stable, halotolerant, and high-alkaline subtilisin from Alkalihalobacillus okhensis Kh10-101T}, series = {FEBS Open Bio}, volume = {12}, journal = {FEBS Open Bio}, number = {10}, publisher = {Wiley}, address = {Hoboken, NJ}, issn = {2211-5463}, doi = {10.1002/2211-5463.13457}, pages = {1729 -- 1746}, year = {2022}, abstract = {Halophilic and halotolerant microorganisms represent a promising source of salt-tolerant enzymes suitable for various biotechnological applications where high salt concentrations would otherwise limit enzymatic activity. Considering the current growing enzyme market and the need for more efficient and new biocatalysts, the present study aimed at the characterization of a high-alkaline subtilisin from Alkalihalobacillus okhensis Kh10-101T. The protease gene was cloned and expressed in Bacillus subtilis DB104. The recombinant protease SPAO with 269 amino acids belongs to the subfamily of high-alkaline subtilisins. The biochemical characteristics of purified SPAO were analyzed in comparison with subtilisin Carlsberg, Savinase, and BPN'. SPAO, a monomer with a molecular mass of 27.1 kDa, was active over a wide range of pH 6.0-12.0 and temperature 20-80 °C, optimally at pH 9.0-9.5 and 55 °C. The protease is highly oxidatively stable to hydrogen peroxide and retained 58\% of residual activity when incubated at 10 °C with 5\% (v/v) H2O2 for 1 h while stimulated at 1\% (v/v) H2O2. Furthermore, SPAO was very stable and active at NaCl concentrations up to 5.0 m. This study demonstrates the potential of SPAO for biotechnological applications in the future.}, language = {en} }