@incollection{DuongSeifarthTemizArtmannetal.2018, author = {Duong, Minh Tuan and Seifarth, Volker and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard and Staat, Manfred}, title = {Growth Modelling Promoting Mechanical Stimulation of Smooth Muscle Cells of Porcine Tubular Organs in a Fibrin-PVDF Scaffold}, series = {Biological, Physical and Technical Basics of Cell Engineering}, booktitle = {Biological, Physical and Technical Basics of Cell Engineering}, editor = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya}, publisher = {Springer}, address = {Singapore}, isbn = {978-981-10-7904-7}, doi = {10.1007/978-981-10-7904-7_9}, pages = {209 -- 232}, year = {2018}, abstract = {Reconstructive surgery and tissue replacements like ureters or bladders reconstruction have been recently studied, taking into account growth and remodelling of cells since living cells are capable of growing, adapting, remodelling or degrading and restoring in order to deform and respond to stimuli. Hence, shapes of ureters or bladders and their microstructure change during growth and these changes strongly depend on external stimuli such as training. We present the mechanical stimulation of smooth muscle cells in a tubular fibrin-PVDFA scaffold and the modelling of the growth of tissue by stimuli. To this end, mechanotransduction was performed with a kyphoplasty balloon catheter that was guided through the lumen of the tubular structure. The bursting pressure was examined to compare the stability of the incubated tissue constructs. The results showed the significant changes on tissues with training by increasing the burst pressure as a characteristic mechanical property and the smooth muscle cells were more oriented with uniformly higher density. Besides, the computational growth models also exhibited the accurate tendencies of growth of the cells under different external stimuli. Such models may lead to design standards for the better layered tissue structure in reconstructing of tubular organs characterized as composite materials such as intestines, ureters and arteries.}, language = {en} } @incollection{DuongNguyenStaat2017, author = {Duong, Minh Tuan and Nguyen, Nhu Huynh and Staat, Manfred}, title = {Physical response of hyperelastic models for composite materials and soft tissues}, series = {Advances in Composite Material}, booktitle = {Advances in Composite Material}, publisher = {Scientific Research Publishing}, address = {Wuhan}, isbn = {978-1-61896-300-0 (Hardcover), 978-1-61896-299-7 (Paperback)}, pages = {316}, year = {2017}, language = {en} } @incollection{DachwaldUlamecBiele2013, author = {Dachwald, Bernd and Ulamec, Stephan and Biele, Jens}, title = {Clean in situ subsurface exploration of icy environments in the solar system}, series = {Habitability of other planets and satellites. - (Cellular origin, life in extreme habitats and astrobiology ; 28)}, booktitle = {Habitability of other planets and satellites. - (Cellular origin, life in extreme habitats and astrobiology ; 28)}, publisher = {Springer}, address = {Dordrecht}, isbn = {978-94-007-6545-0 (Druckausgabe)}, pages = {367 -- 397}, year = {2013}, abstract = {"To assess the habitability of the icy environments in the solar system, for example, on Mars, Europa, and Enceladus, the scientific analysis of material embedded in or underneath their ice layers is very important. We consider self-steering robotic ice melting probes to be the best method to cleanly access these environments, that is, in compliance with planetary protection standards. The required technologies are currently developed and tested."}, language = {en} } @incollection{GohTopcuMadabhushietal.2024, author = {Goh, Kheng Lim and Top{\c{c}}u, Murat and Madabhushi, Gopal S. P. and Staat, Manfred}, title = {Collagen fibril reinforcement in connective tissue extracellular matrices}, series = {Handbook of the extracellular matrix}, booktitle = {Handbook of the extracellular matrix}, editor = {Maia, Fatima Raquel Azevedo and Miguel Oliveira, J. and Reis, Rui L.}, publisher = {Springer Nature}, address = {Cham}, isbn = {978-3-031-56362-1 (Print)}, doi = {10.1007/978-3-031-56363-8_6}, pages = {89 -- 108}, year = {2024}, abstract = {The connective tissues such as tendons contain an extracellular matrix (ECM) comprising collagen fibrils scattered within the ground substance. These fibrils are instrumental in lending mechanical stability to tissues. Unfortunately, our understanding of how collagen fibrils reinforce the ECM remains limited, with no direct experimental evidence substantiating current theories. Earlier theoretical studies on collagen fibril reinforcement in the ECM have relied predominantly on the assumption of uniform cylindrical fibers, which is inadequate for modelling collagen fibrils, which possessed tapered ends. Recently, Top{\c{c}}u and colleagues published a paper in the International Journal of Solids and Structures, presenting a generalized shear-lag theory for the transfer of elastic stress between the matrix and fibers with tapered ends. This paper is a positive step towards comprehending the mechanics of the ECM and makes a valuable contribution to formulating a complete theory of collagen fibril reinforcement in the ECM.}, language = {en} }