@article{NiedermeierPennerUsherovichetal.2023, author = {Niedermeier, Jana and Penner, Crystal and Usherovich, Samuel and B{\´e}langer-Champagne, Camille and Paulßen, Elisabeth and Hoehr, Cornelia}, title = {Optical Fibers as Dosimeter Detectors for Mixed Proton/Neutron Fields - A Biological Dosimeter}, series = {electronics}, volume = {12}, journal = {electronics}, number = {2}, publisher = {MDPI}, address = {Basel}, issn = {2079-9292}, doi = {10.3390/electronics12020324}, pages = {11 Seiten}, year = {2023}, abstract = {In recent years, proton therapy has gained importance as a cancer treatment modality due to its conformality with the tumor and the sparing of healthy tissue. However, in the interaction of the protons with the beam line elements and patient tissues, potentially harmful secondary neutrons are always generated. To ensure that this neutron dose is as low as possible, treatment plans could be created to also account for and minimize the neutron dose. To monitor such a treatment plan, a compact, easy to use, and inexpensive dosimeter must be developed that not only measures the physical dose, but which can also distinguish between proton and neutron contributions. To that end, plastic optical fibers with scintillation materials (Gd₂O₂S:Tb, Gd₂O₂S:Eu, and YVO₄:Eu) were irradiated with protons and neutrons. It was confirmed that sensors with different scintillation materials have different sensitivities to protons and neutrons. A combination of these three scintillators can be used to build a detector array to create a biological dosimeter.}, language = {en} } @article{RuebbelkeVoegeleGrajewskietal.2023, author = {R{\"u}bbelke, Dirk and V{\"o}gele, Stefan and Grajewski, Matthias and Zobel, Luzy}, title = {Cross border adjustment mechanism: Initial data for the assessment of hydrogen-based steel production}, series = {Data in Brief}, volume = {47}, journal = {Data in Brief}, number = {Article 108907}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2352-3409}, doi = {10.1016/j.dib.2023.108907}, pages = {1 -- 5}, year = {2023}, abstract = {Ambitious climate targets affect the competitiveness of industries in the international market. To prevent such industries from moving to other countries in the wake of increased climate protection efforts, cost adjustments may become necessary. Their design requires knowledge of country-specific production costs. Here, we present country-specific cost figures for different production routes of steel, paying particular attention to transportation costs. The data can be used in floor price models aiming to assess the competitiveness of different steel production routes in different countries (R{\"u}bbelke, 2022).}, language = {en} } @article{HaegerGrankinWagner2023, author = {Haeger, Gerrit and Grankin, Alina and Wagner, Michaela}, title = {Construction of an Aspergillus oryzae triple amylase deletion mutant as a chassis to evaluate industrially relevant amylases using multiplex CRISPR/Cas9 editing technology}, series = {Applied Research}, journal = {Applied Research}, number = {Early View}, publisher = {Wiley-VCH}, issn = {2702-4288}, doi = {10.1002/appl.202200106}, pages = {1 -- 15}, year = {2023}, abstract = {Aspergillus oryzae is an industrially relevant organism for the secretory production of heterologous enzymes, especially amylases. The activities of potential heterologous amylases, however, cannot be quantified directly from the supernatant due to the high background activity of native α-amylase. This activity is caused by the gene products of amyA, amyB, and amyC. In this study, an in vitro CRISPR/Cas9 system was established in A. oryzae to delete these genes simultaneously. First, pyrG of A. oryzae NSAR1 was mutated by exploiting NHEJ to generate a counter-selection marker. Next, all amylase genes were deleted simultaneously by co-transforming a repair template carrying pyrG of Aspergillus nidulans and flanking sequences of amylase gene loci. The rate of obtained triple knock-outs was 47\%. We showed that triple knockouts do not retain any amylase activity in the supernatant. The established in vitro CRISPR/Cas9 system was used to achieve sequence-specific knock-in of target genes. The system was intended to incorporate a single copy of the gene of interest into the desired host for the development of screening methods. Therefore, an integration cassette for the heterologous Fpi amylase was designed to specifically target the amyB locus. The site-specific integration rate of the plasmid was 78\%, with exceptional additional integrations. Integration frequency was assessed via qPCR and directly correlated with heterologous amylase activity. Hence, we could compare the efficiency between two different signal peptides. In summary, we present a strategy to exploit CRISPR/Cas9 for gene mutation, multiplex knock-out, and the targeted knock-in of an expression cassette in A. oryzae. Our system provides straightforward strain engineering and paves the way for development of fungal screening systems.}, language = {en} } @article{FayyaziSardarThomasetal.2023, author = {Fayyazi, Mojgan and Sardar, Paramjotsingh and Thomas, Sumit Infent and Daghigh, Roonak and Jamali, Ali and Esch, Thomas and Kemper, Hans and Langari, Reza and Khayyam, Hamid}, title = {Artificial intelligence/machine learning in energy management systems, control, and optimization of hydrogen fuel cell vehicles}, volume = {15}, number = {6}, publisher = {MDPI}, address = {Basel}, doi = {10.3390/su15065249}, pages = {38}, year = {2023}, abstract = {Environmental emissions, global warming, and energy-related concerns have accelerated the advancements in conventional vehicles that primarily use internal combustion engines. Among the existing technologies, hydrogen fuel cell electric vehicles and fuel cell hybrid electric vehicles may have minimal contributions to greenhouse gas emissions and thus are the prime choices for environmental concerns. However, energy management in fuel cell electric vehicles and fuel cell hybrid electric vehicles is a major challenge. Appropriate control strategies should be used for effective energy management in these vehicles. On the other hand, there has been significant progress in artificial intelligence, machine learning, and designing data-driven intelligent controllers. These techniques have found much attention within the community, and state-of-the-art energy management technologies have been developed based on them. This manuscript reviews the application of machine learning and intelligent controllers for prediction, control, energy management, and vehicle to everything (V2X) in hydrogen fuel cell vehicles. The effectiveness of data-driven control and optimization systems are investigated to evolve, classify, and compare, and future trends and directions for sustainability are discussed.}, language = {en} } @incollection{EngelmannBaumann2023, author = {Engelmann, Ulrich M. and Baumann, Martin}, title = {Moderationsexpertise f{\"u}r QMBs - die Methoden}, series = {Qualit{\"a}tsmanagement im Gesundheitswesen}, booktitle = {Qualit{\"a}tsmanagement im Gesundheitswesen}, editor = {Herbig, Nicola and Poppelreuter, Stefan}, edition = {60. Update}, publisher = {T{\"U}V-Verlag}, address = {K{\"o}ln}, isbn = {978-3-8249-0714-4}, pages = {Kapitel 10815}, year = {2023}, abstract = {Damit Sie als Moderator effektiv und professionell moderieren k{\"o}nnen, sollten Sie die entsprechenden Methoden kennen. Mit den richtigen Methoden k{\"o}nnen Sie Diskussionen leiten, Konflikte l{\"o}sen, die Teilnehmer motivieren und daf{\"u}r sorgen, dass die Ziele der Veranstaltung erreicht werden. Außerdem helfen sie Ihnen, eine positive Atmosph{\"a}re zu schaffen und das Interesse der Teilnehmer zu halten. In diesem zweiten Beitrag der mehrteiligen Serie lernen Sie die grunds{\"a}tzlichen Methoden kennen, um erfolgreiche Teamsitzungen, Arbeitsgruppentreffen, Kick-offs und Meetings durchzuf{\"u}hren.}, language = {de} } @masterthesis{Heising2023, type = {Bachelor Thesis}, author = {Heising, Michelle}, title = {Nachhaltige Gestaltung im urbanen {\"o}ffentlichen Raum : erneuerbare Energien in Begegnungsr{\"a}ume integrieren}, publisher = {FH Aachen}, address = {Aachen}, pages = {83 Seiten}, year = {2023}, abstract = {RƎURB (Reurbanization \& Renewable Energy) ist ein Konzept zur Integration von erneuerbaren Energien in einen urbanen Begegnungsraum. Es beinhaltet das Design eines skulpturalen Kleinwindkraftwerks und eines Solar-Pavillons mit einer Sitzlandschaft f{\"u}r einen energieautarken, {\"o}ffentlichen Platz. Durch die Integration eines W-LAN Hotspots und Ladem{\"o}glichkeiten in der Sitzlandschaft bringt RƎURB nicht nur gr{\"u}nen Strom in die Stadt, sondern gew{\"a}hrleistet der Bev{\"o}lkerung auch Zugang zur Digitalisierung und einen kostenlosen Arbeitsraum. Windturbine: Herk{\"o}mmliche Windr{\"a}der k{\"o}nnen in der Stadt nicht genutzt werden. Die RƎURB-Winds{\"a}ule ist darauf spezialisiert, die urbanen Winde aus allen Richtungen aufzunehmen und funktioniert schon bei einem leichten Windstoß. Durch das elegante Design lassen sich die Technologien als {\"a}sthetischen Blickfang in das moderne Stadtbild integrieren.}, language = {de} } @masterthesis{Hatke2023, type = {Bachelor Thesis}, author = {Hatke, Lars}, title = {X Plore: human hybrid submarine}, publisher = {FH Aachen}, address = {Aachen}, pages = {153 Seiten}, year = {2023}, abstract = {Das „X Plore" ist ein human hybrid angetriebenes Tauchboot, welches sowohl f{\"u}r den touristischen als auch privaten Gebrauch konzipiert ist. Das immersive Design des „X Plore" sorgt f{\"u}r ein eindrucksvolles Taucherlebnis. Das Konzept soll die Menschen {\"u}ber die aktuelle Not der Meere und ihrer Lebewesen aufkl{\"a}ren und ihnen gleichzeitig die M{\"o}glichkeit geben, der Unterwasserwelt n{\"a}her zukommen. Zudem soll es diese erhalten und ihre Bewohner:innen sch{\"u}tzen. Des Weiteren thematisiert die Arbeit zukunftsorientierte Antriebs- und Batterietechniken und setzt sich mit der sinnvollen Integrierung dieser auseinander.}, language = {de} } @masterthesis{Herrmann2023, type = {Bachelor Thesis}, author = {Herrmann, Luna}, title = {Blind Shopping}, publisher = {FH Aachen}, address = {Aachen}, pages = {104 Seiten}, year = {2023}, abstract = {Das Einkaufen in Einkaufszentren oder Ladenstraßen ist f{\"u}r Menschen ohne Sehbehinderung eine selbstverst{\"a}ndliche T{\"a}tigkeit. F{\"u}r Menschen mit Sehbehinderung gibt es bis heute keine M{\"o}glichkeit, sich ohne Hilfe von Familienmitgliedern, Freund:innen oder Pflegepersonal in einem Einkaufszentrum zurechtzufinden. Genau dieses Problem l{\"o}st "NAVON.". Er ist ein intelligenter und smarter Blindenstock, welcher durch Ultraschalldistanzsensoren fr{\"u}hzeitig Hindernisse erkennt und die M{\"o}glichkeit bietet, den Betroffenen durch das Einkaufszentrum zu lotsen. Die Logik des Systems liegt innerhalb des Handgriffs, welcher die wichtigsten Einstellungen bzgl. Sprache und haptischer Bedienelemente steuert. Ebenfalls gibt er dem Betroffenen auch ein haptisches Feedback, um Hindernisse fr{\"u}hzeitig umgehen zu k{\"o}nnen. "NAVON." ist ein wichtiger Ansatz f{\"u}r eine neue Kategorie von Produkten und Blindenst{\"o}cken. Dar{\"u}ber hinaus birgt das Konzept auch weitere Potenziale f{\"u}r {\"o}ffentliche Geb{\"a}ude ({\"A}mter, Krankenh{\"a}user, etc..).}, language = {de} } @masterthesis{Lorse2023, type = {Bachelor Thesis}, author = {Lorse, Hannah}, title = {Gem{\"u}sevolle Aussichten : eine bunte Sammlung essbarer Pflanzenteile}, publisher = {FH Aachen}, address = {Aachen}, pages = {92 Seiten}, year = {2023}, abstract = {Die Bachelorarbeit „Gem{\"u}sevolle Aussichten" / „Eine bunte Sammlung essbarer Pflanzenteile" umfasst eine illustrative Auseinandersetzung, bunte Sammlung essbarer Pflanzenteile (Gem{\"u}se). Mit ihr entsteht ein visueller Anreiz, sich mehr mit dem gesunden Nahrungsmittel auseinanderzusetzen. Viele Kinder sowie Erwachsene kennen viele Gem{\"u}sesorten {\"u}berhaupt nicht, Gem{\"u}se wie z. B. Schwarzwurzeln, Pastinaken oder gar Fenchel ist oftmals wenig bekannt. Mit der Arbeit wird ein informeller, illustrativer {\"U}berblick {\"u}ber Gem{\"u}se geschaffen, um zum Beispiel auch {\"u}ber die Inhaltsstoffe zu informieren. Denn viele wissen gar nicht, was eigentlich in dem wertvollen Nahrungsmitteln steckt, wie gut ein regelm{\"a}ßiger Konsum von Gem{\"u}se eigentlich f{\"u}r uns ist. Dabei hat der t{\"a}gliche Konsum von verschiedenen Gem{\"u}sesorten nicht nur eine Auswirkung auf die k{\"o}rperliche sondern auch auf die mentale Gesundheit. Viele Gem{\"u}sesorten beinhalten bestimmte Vitamine oder weitere Inhaltsstoffe, die sich positiv auf unsere Psyche auswirken und dazu beitragen, zum Bespiel einen depressiven Zustand zu verbessern. Auch die Umwelt kann von einem h{\"a}ufigeren Konsum von Gem{\"u}se anstatt Fleisch profitieren. Denn bei der Produktion von Fleisch entsteht viel mehr Kohlenstoffdioxid als bei der Produktion von Gem{\"u}se. Auch der Anteil des virtuellen Wassers ist bei der Produktion von Fleisch viel h{\"o}her. Das Projekt besteht aus einem fadengebundenen Hardcover-Buch und einer Poster-Serie. Zu Beginn der Arbeit wird eine allgemeine Einleitung in das Thema Gem{\"u}se gegeben. Im folgenden Hauptteil werden verschiedene Gem{\"u}segruppen und einige der zugeh{\"o}rigen Sorten visuell und informativ erkl{\"a}rt. Bei der Poster-Serie wurden die sechs Hauptfarben, die jeweiligen Gem{\"u}seillustrationen separiert und im Stil der Arbeit nummeriert benannt. Mit dem Projekt soll die Unwissenheit {\"u}ber viele Gem{\"u}sesorten gesenkt und der Konsum von weniger Fleisch und mehr Gem{\"u}se angeregt werden.}, language = {de} } @masterthesis{Martinez2023, type = {Bachelor Thesis}, author = {Martinez, Mariana}, title = {The Taste of Memories : a recipe book of memories}, publisher = {FH Aachen}, address = {Aachen}, pages = {110 Seiten}, year = {2023}, abstract = {What does the word 'home' means and at what age do we give it meaning? Many of us grew up in one, in a home that our parents, grandparents, aunts, uncles and relatives shaped. Who, as we grew up, taught us about the world from their perspective as we interpreted and saw it for the first time and with it, its colors, its smells, its tastes, its sounds, its dances, and its languages. When we migrate, we take all that with us, like a piece of luggage that was stored in some corner inside a lung, or inside the memory in a heart's artery. And then you arrive in this new world, which we were told was the Old World, with other colors, other flavors, other words, in which yours no longer make sense. And you try to connect with all your senses, but, above all, we try to belong, because we belonged all our lives to something, to someone, to some place where we learned to be. When we migrate, without saying, we go through the grieve that comes with the beautiful discomfort of leaving everything we once knew. We mourn, because we can't go to lunch at our grandmas on Sundays, or have mom bring us soup when we are sick, or the Christmas meals and celebrations that we like so much, or that special dish that was made for us on our birthdays or on a family BBQ on a Sunday or a holiday. I wonder if emotions come inside us through the taste and respiratory track, if it is that we breathe life, and with that what we love finds its ways inside and finds its corner somewhere in the body. If what we have loved and what we have lived hides somewhere in our body, I doubtlessly think it came in through one of our senses, and in this attempt at my first illustrated book I'll share which, I think, are the senses through which at first instance part of what we perceive as cultural identity enters.}, language = {de} }