@inproceedings{FerreinMaierMuehlbacheretal.2016,
  author    = {Ferrein, Alexander and Maier, Christopher and M{\"u}hlbacher, Clemens and Niem{\"u}ller, Tim and Steinbauer, Gerald and Vassos, Stravros},
  title     = {Controlling logistics robots with the action-based language YAGI},
  series = {Intelligent Robotics and Applications: 9th International Conference, ICIRA 2016, Tokyo, Japan, August 22-24, 2016, Proceedings, Part I},
  volume    = {9834},
  booktitle = {Intelligent Robotics and Applications: 9th International Conference, ICIRA 2016, Tokyo, Japan, August 22-24, 2016, Proceedings, Part I},
  publisher = {Springer},
  isbn      = {978-3-319-43505-3 (Print)},
  doi       = {10.1007/978-3-319-43506-0_46},
  pages     = {525 -- 537},
  year      = {2016},
  language  = {en}
}
@incollection{FeldmannDoeringPyschny2016,
  author    = {Feldmann, M. and D{\"o}ring, Bernd and Pyschny, D.},
  title     = {Floor systems; Sustainabilty analyses and assessments of steel bridges},
  series = {Sustainable steel buildings : a practical guide for structures and envelopes},
  booktitle = {Sustainable steel buildings : a practical guide for structures and envelopes},
  publisher = {Wiley Blackwell},
  address   = {Chichester, West Sussex},
  isbn      = {978-1-118-74079-8 (PDF)},
  pages     = {198 -- 223},
  year      = {2016},
  language  = {en}
}
@inproceedings{EngelThieringerTippkoetter2016,
  author    = {Engel, Mareike and Thieringer, Julia and Tippk{\"o}tter, Nils},
  title     = {Linking bioprocess engineering and electrochemistry for sustainable biofuel production},
  series = {Young Researchers Symposium, YRS 2016. Proceedings},
  booktitle = {Young Researchers Symposium, YRS 2016. Proceedings},
  publisher = {Fraunhofer Verlag},
  address   = {Karlsruhe},
  pages     = {49 -- 53},
  year      = {2016},
  abstract  = {Electromicrobial engineering is an emerging, highly interdisciplinary research area linking bioprocesses with electrochemistry. In this work, microbial electrosynthesis (MES) of biobutanol is carried out during acetone-butanol-ethanol (ABE) fermentations with Clostridium acetobutylicum. A constant electric potential of -600mV (vs. Ag/AgCl) with simultaneous addition of the soluble redox mediator neutral red is used in order to study the electron transfer between the working electrode and the bacterial cells. The results show an earlier initiation of solvent production for all fermentations with applied potential compared to the conventional ABE fermentation. The f inal butanol concentration can be more than doubled by the application of a negative potential combined with addition of neutral red. Moreover a higher biofilm formation on the working electrode compared to control cultivations has been observed. In contrast to previous studies, our results also indicate that direct electron transfer (DET) might be possible with C. acetobutylicum. The presented results make microbial butanol production economically attractive and therefore support the development of sustainable production processes in the chemical industry aspired by the "Centre for resource-efficient chemistry and raw material change" as well as the the project "NanoKat" working on nanostructured catalysts in Kaiserslautern.},
  language  = {en}
}
@inproceedings{EngelThieringerTippkoetter2016,
  author    = {Engel, M. and Thieringer, J. and Tippk{\"o}tter, Nils},
  title     = {Microbial electrosynthesis for sustainable biobutanol production},
  series = {New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany},
  booktitle = {New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany},
  publisher = {DECHEMA},
  address   = {Frankfurt am Main},
  pages     = {77 -- 78},
  year      = {2016},
  language  = {en}
}
@inproceedings{DuongJungFrotscheretal.2016,
  author    = {Duong, Minh Tuan and Jung, Alexander and Frotscher, Ralf and Staat, Manfred},
  title     = {A 3D electromechanical FEM-based model for cardiac tissue},
  series = {ECCOMAS Congress 2016, VII European Congress on Computational Methods in Applied Sciences and Engineering. Crete Island, Greece, 5-10 June 2016},
  booktitle = {ECCOMAS Congress 2016, VII European Congress on Computational Methods in Applied Sciences and Engineering. Crete Island, Greece, 5-10 June 2016},
  editor    = {Papadrakakis, M.},
  pages     = {13 S.},
  year      = {2016},
  language  = {en}
}
@inproceedings{DroszezSannoGoldmannetal.2016,
  author    = {Droszez, Anna and Sanno, Maximilian and Goldmann, Jan-Peter and Albracht, Kirsten and Br{\"u}ggemann, Gerd-Peter and Braunstein, Bjoern},
  title     = {Differences between take-off behavior during vertical jumps and two artistic elements},
  series = {34th International Conference of Biomechanics in Sport, Tsukuba, Japan, July 18-22, 2016},
  booktitle = {34th International Conference of Biomechanics in Sport, Tsukuba, Japan, July 18-22, 2016},
  issn      = {1999-4168},
  pages     = {577 -- 580},
  year      = {2016},
  language  = {en}
}
@article{DollWagnerWagneretal.2016,
  author    = {Doll, Theodor and Wagner, Torsten and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Engineering of functional interfaces / Theodor Doll ; Torsten Wagner ; Patrick Wagner ; Michael J. Sch{\"o}ning (eds.)},
  series = {Physica status solidi (a)},
  volume    = {213},
  journal   = {Physica status solidi (a)},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201670641},
  pages     = {1393 -- 1394},
  year      = {2016},
  language  = {en}
}
@article{DiktaReisselHarlass2016,
  author    = {Dikta, Gerhard and Reißel, Martin and Harlaß, Carsten},
  title     = {Semi-parametric survival function estimators deduced from an identifying Volterra type integral equation},
  series = {Journal of multivariate analysis},
  journal   = {Journal of multivariate analysis},
  number    = {147},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.jmva.2016.02.008},
  pages     = {273 -- 284},
  year      = {2016},
  abstract  = {Based on an identifying Volterra type integral equation for randomly right censored observations from a lifetime distribution function F, we solve the corresponding estimating equation by an explicit and implicit Euler scheme. While the first approach results in some known estimators, the second one produces new semi-parametric and pre-smoothed Kaplan-Meier estimators which are real distribution functions rather than sub-distribution functions as the former ones are. This property of the new estimators is particular useful if one wants to estimate the expected lifetime restricted to the support of the observation time. Specifically, we focus on estimation under the semi-parametric random censorship model (SRCM), that is, a random censorship model where the conditional expectation of the censoring indicator given the observation belongs to a parametric family. We show that some estimated linear functionals which are based on the new semi-parametric estimator are strong consistent, asymptotically normal, and efficient under SRCM. In a small simulation study, the performance of the new estimator is illustrated under moderate sample sizes. Finally, we apply the new estimator to a well-known real dataset.},
  language  = {en}
}
@article{DantismTakenagaWagneretal.2016,
  author    = {Dantism, Shahriar and Takenaga, Shoko and Wagner, Patrick and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Determination of the extracellular acidification of Escherichia coli K12 with a multi-​chamber-​based LAPS system},
  series = {Physica status solidi (a)},
  volume    = {213},
  journal   = {Physica status solidi (a)},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6300},
  doi       = {10.1002/pssa.201533043},
  pages     = {1479 -- 1485},
  year      = {2016},
  abstract  = {On-line monitoring of the metabolic activity of microorganisms involved in intermediate stages of biogas production plays an important role to avoid undesirable "down times" during the biogas production. In order to control this process, an on-chip differential measuring system based on the light-addressable potentiometric sensor (LAPS) principle combined with a 3D-printed multi-chamber structure has been realized. As a test microorganism, Escherichia coli K12 (E. coli K12) were used for cell-based measurements. Multi-chamber structures were developed to determine the metabolic activity of E. coli K12 in suspension for a different number of cells, responding to the addition of a constant or variable amount of glucose concentrations, enabling differential and simultaneous measurements.},
  language  = {en}
}
@article{DallasSalphatiGomezZepedaetal.2016,
  author    = {Dallas, Shannon and Salphati, Laurent and Gomez-Zepeda, David and Wanek, Thomas and Chen, Liangfu and Chu, Xiaoyan and Kunta, Jeevan and Mezler, Mario and Menet, Marie-Claude and Chasseigneaux, Stephanie and Decl{\`e}ves, Xavier and Langer, Oliver and Pierre, Esaie and DiLoreto, Karen and Hoft, Carolin and Laplanche, Loic and Pang, Jodie and Pereira, Tony and Andonian, Clara and Simic, Damir and Rode, Anja and Yabut, Jocelyn and Zhang, Xiaolin and Scheer, Nico},
  title     = {Generation and Characterization of a Breast Cancer Resistance Protein Humanized Mouse Model},
  series = {Molecular Pharmacology},
  volume    = {89},
  journal   = {Molecular Pharmacology},
  number    = {5},
  publisher = {ASPET},
  address   = {Bethesda, Md.},
  issn      = {1521-0111},
  doi       = {10.1124/mol.115.102079},
  pages     = {492 -- 504},
  year      = {2016},
  abstract  = {Breast cancer resistance protein (BCRP) is expressed in various tissues, such as the gut, liver, kidney and blood brain barrier (BBB), where it mediates the unidirectional transport of substrates to the apical/luminal side of polarized cells. Thereby BCRP acts as an efflux pump, mediating the elimination or restricting the entry of endogenous compounds or xenobiotics into tissues and it plays important roles in drug disposition, efficacy and safety. Bcrp knockout mice (Bcrp-/-) have been used widely to study the role of this transporter in limiting intestinal absorption and brain penetration of substrate compounds. Here we describe the first generation and characterization of a mouse line humanized for BCRP (hBCRP), in which the mouse coding sequence from the start to stop codon was replaced with the corresponding human genomic region, such that the human transporter is expressed under control of the murine Bcrp promoter. We demonstrate robust human and loss of mouse BCRP/Bcrp mRNA and protein expression in the hBCRP mice and the absence of major compensatory changes in the expression of other genes involved in drug metabolism and disposition. Pharmacokinetic and brain distribution studies with several BCRP probe substrates confirmed the functional activity of the human transporter in these mice. Furthermore, we provide practical examples for the use of hBCRP mice to study drug-drug interactions (DDIs). The hBCRP mouse is a promising model to study the in vivo role of human BCRP in limiting absorption and BBB penetration of substrate compounds and to investigate clinically relevant DDIs involving BCRP.},
  language  = {en}
}