@incollection{AzatKerimkulovaMansurovetal.2020, author = {Azat, Seitkhan and Kerimkulova, Almagul R. and Mansurov, Zulkhair A. and Adekenov, Sergazy and Artmann, Gerhard}, title = {The Use of Fusicoccin as Anticancer Compound}, series = {Carbon Nanomaterials in Biomedicine and the Environment}, booktitle = {Carbon Nanomaterials in Biomedicine and the Environment}, publisher = {Jenny Stanford Publishing}, address = {New York}, isbn = {978-0-429-42864-7}, doi = {10.1201/9780429428647-8}, pages = {149 -- 172}, year = {2020}, abstract = {The problem of creation and use of sorption materials is of current interest for the practice of the modern medicine and agriculture. Practical importance is production of a biostimulant using a carbon sorbent for a significant increase in productivity, which is very relevant for the regions of Kazakhstan. It is known that a plant phytohormone—fusicoccin—in nanogram concentrations transforms cancer cells to the state of apoptosis. In this regard, there is a scientific practical interest in the development of a highly efficient method for producing fusicoccin from extract of germinated wheat seeds. According to the results of computer modeling, cleaning composite components of fusicoccin using microporous carbon adsorbents not suitable as the size of the molecule of fusicoccin more than micropores and the optimum pore size for purification of constituents of fusicoccin was determined by computer simulation.}, language = {en} } @article{BayerTemizArtmannDigeletal.2020, author = {Bayer, Robin and Temiz Artmann, Ayseg{\"u}l and Digel, Ilya and Falkenstein, Julia and Artmann, Gerhard and Creutz, Till and Hescheler, J{\"u}rgen}, title = {Mechano-pharmacological testing of L-Type Ca²⁺ channel modulators via human vascular celldrum model}, series = {Cellular Physiology and Biochemistry}, volume = {54}, journal = {Cellular Physiology and Biochemistry}, publisher = {Cell Physiol Biochem Press}, address = {D{\"u}sseldorf}, issn = {1421-9778}, doi = {10.33594/000000225}, pages = {371 -- 383}, year = {2020}, abstract = {Background/Aims: This study aimed to establish a precise and well-defined working model, assessing pharmaceutical effects on vascular smooth muscle cell monolayer in-vitro. It describes various analysis techniques to determine the most suitable to measure the biomechanical impact of vasoactive agents by using CellDrum technology. Methods: The so-called CellDrum technology was applied to analyse the biomechanical properties of confluent human aorta muscle cells (haSMC) in monolayer. The cell generated tensions deviations in the range of a few N/m² are evaluated by the CellDrum technology. This study focuses on the dilative and contractive effects of L-type Ca²⁺ channel agonists and antagonists, respectively. We analyzed the effects of Bay K8644, nifedipine and verapamil. Three different measurement modes were developed and applied to determine the most appropriate analysis technique for the study purpose. These three operation modes are called, particular time mode" (PTM), "long term mode" (LTM) and "real-time mode" (RTM). Results: It was possible to quantify the biomechanical response of haSMCs to the addition of vasoactive agents using CellDrum technology. Due to the supplementation of 100nM Bay K8644, the tension increased approximately 10.6\% from initial tension maximum, whereas, the treatment with nifedipine and verapamil caused a significant decrease in cellular tension: 10nM nifedipine decreased the biomechanical stress around 6,5\% and 50nM verapamil by 2,8\%, compared to the initial tension maximum. Additionally, all tested measurement modes provide similar results while focusing on different analysis parameters. Conclusion: The CellDrum technology allows highly sensitive biomechanical stress measurements of cultured haSMC monolayers. The mechanical stress responses evoked by the application of vasoactive calcium channel modulators were quantified functionally (N/m²). All tested operation modes resulted in equal findings, whereas each mode features operation-related data analysis.}, language = {en} } @inproceedings{BedburMoorkampPetersonetal.2020, author = {Bedbur, Christian and Moorkamp, Wilfried and Peterson, Leif Arne and Uibel, Thomas}, title = {Holzbr{\"u}cken mit Natursteinbel{\"a}gen - Untersuchungen zur Aktivierung der Verbundwirkung}, series = {Doktorandenkolloquium Holzbau Forschung + Praxis : Stuttgart, 05. + 06. M{\"a}rz 2020}, booktitle = {Doktorandenkolloquium Holzbau Forschung + Praxis : Stuttgart, 05. + 06. M{\"a}rz 2020}, editor = {Kuhlmann, Ulrike}, publisher = {Universit{\"a}t Stuttgart, Institut f{\"u}r Konstruktion und Entwurf}, address = {Stuttgart}, pages = {53 -- 60}, year = {2020}, language = {de} } @article{BensbergAuthCzarnecki2020, author = {Bensberg, Frank and Auth, Gunnar and Czarnecki, Christian}, title = {Literaturanalyse mit Text Mining}, series = {E-Learning and Education (eleed)}, journal = {E-Learning and Education (eleed)}, number = {13}, editor = {Haake, J{\"o}rg M.}, publisher = {FernUniversit{\"a}t in Hagen}, address = {Hagen}, issn = {1860-7470}, pages = {1 -- 13}, year = {2020}, abstract = {Die Durchf{\"u}hrung einer systematischen Literaturrecherche ist eine zentrale Kompetenz wissenschaftlichen Arbeitens und bildet daher einen festen Ausbildungsbestandteil von Bachelor- und Masterstudieng{\"a}ngen. In entsprechenden Lehrveranstaltungen werden Studierende zwar mit den grundlegenden Hilfsmitteln zur Suche und Verwaltung von Literatur vertraut gemacht, allerdings werden die Potenziale textanalytischer Methoden und Anwendungssysteme (Text Mining, Text Analytics) dabei zumeist nicht abgedeckt. Folglich werden Datenkompetenzen, die zur systemgest{\"u}tzten Analyse und Erschließung von Literaturdaten erforderlich sind, nicht hinreichend ausgepr{\"a}gt. Um diese Kompetenzl{\"u}cke zu adressieren, ist an der Hochschule Osnabr{\"u}ck eine Lehrveranstaltung konzipiert und projektorientiert umgesetzt worden, die sich insbesondere an Studierende wirtschaftswissenschaftlicher Studieng{\"a}nge richtet. Dieser Beitrag dokumentiert die fachliche sowie technische Ausgestaltung dieser Veranstaltung und zeigt Potenziale f{\"u}r die k{\"u}nftige Weiterentwicklung auf.}, language = {de} } @incollection{BorchertTenbrake2020, author = {Borchert, J{\"o}rg and Tenbrake, Andre}, title = {Bewirtschaftung von Flexibilit{\"a}t {\"u}ber Microservices eines Plattformanbieters}, series = {Realisierung Utility 4.0 Band 1}, booktitle = {Realisierung Utility 4.0 Band 1}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-25332-5}, doi = {10.1007/978-3-658-25332-5_37}, pages = {615 -- 626}, year = {2020}, abstract = {Die Energiewirtschaft befindet sich in einem starken Wandel, der v. a. durch die Energiewende und Digitalisierung Druck auf s{\"a}mtliche Marktteilnehmer aus{\"u}bt. Das klassische Gesch{\"a}ftsmodell des Energieversorgungsunternehmens ver{\"a}ndert sich dabei grundlegend. Der kontinuierlich ansteigende Einsatz dezentraler und volatiler Erzeugungsanlagen macht die Identifikation von Flexibilit{\"a}tspotenzialen notwendig, um weiterhin eine hohe Versorgungssicherheit zu gew{\"a}hrleisten. Dieser Schritt ist nur mit einem hohen Digitalisierungsgrad m{\"o}glich. Eine funktionale Plattform mit Microservices, die zu Gesch{\"a}ftsprozessen verbunden werden k{\"o}nnen, wird als M{\"o}glichkeit zur Aktivierung der Flexibilit{\"a}t und Digitalisierung der Energieversorgungsunternehmen im Folgenden vorgestellt.}, language = {de} } @inproceedings{BraunChengDoweyetal.2020, author = {Braun, Sebastian and Cheng, Chi-Tsun and Dowey, Steve and Wollert, J{\"o}rg}, title = {Survey on Security Concepts to Adapt Flexible Manufacturing and Operations Management based upon Multi-Agent Systems}, series = {2020 IEEE 29th International Symposium on Industrial Electronics (ISIE)}, booktitle = {2020 IEEE 29th International Symposium on Industrial Electronics (ISIE)}, doi = {10.1109/ISIE45063.2020.9152210}, year = {2020}, language = {en} } @phdthesis{Bronder2020, author = {Bronder, Thomas}, title = {Label-free detection of tuberculosis DNA with capacitive field-effect biosensors}, publisher = {Philipps-Universit{\"a}t Marburg}, address = {Marburg}, doi = {10.17192/z2021.0056}, pages = {X, 162 S}, year = {2020}, language = {en} } @article{BungCrookstonValero2020, author = {Bung, Daniel B. and Crookston, Brian M. and Valero, Daniel}, title = {Turbulent free-surface monitoring with an RGB-D sensor: the hydraulic jump case}, series = {Journal of Hydraulic Research}, journal = {Journal of Hydraulic Research}, publisher = {Taylor \& Francis}, address = {London}, issn = {1814-2079}, doi = {10.1080/00221686.2020.1844810}, year = {2020}, language = {en} } @article{BungErpicumTullis2020, author = {Bung, Daniel Bernhard and Erpicum, S{\´e}bastien and Tullis, Blanke P.}, title = {Advances in hydraulic structures engineering}, series = {Journal of Hydraulic Engineering}, volume = {147}, journal = {Journal of Hydraulic Engineering}, number = {1}, publisher = {ASCE}, address = {Reston, Va.}, issn = {0733-9429 (Druckausgabe)}, doi = {10.1061/(ASCE)HY.1943-7900.0001851}, pages = {1 Seite}, year = {2020}, language = {en} } @book{ButenwegHoffmeisterHoltschoppenetal.2020, author = {Butenweg, Christoph and Hoffmeister, Benno and Holtschoppen, Britta and Klinkel, Sven and Rosin, Julia and Schmitt, Timo}, title = {Seismic design of industrial facilities 2020: proceedings of the 2nd International Conference on Seismic Design of Industrial Facilities (SeDIF-Conference)}, publisher = {Apprimus Verlag}, address = {Aachen}, isbn = {978-3-86359-729-0}, pages = {524 Seiten}, year = {2020}, language = {en} }