@misc{RathSeitz1993, author = {Rath, Walter and Seitz, Karsten}, title = {Fr{\"u}hregenfeste Dichtmasse auf Basis w{\"a}ssriger Acrylatdispersionen und Verfahren zu ihrer Herstellung}, publisher = {Deutsches Patent- und Markenamt}, address = {M{\"u}nchen}, year = {1993}, language = {de} } @article{ZientzBongaertsUnden1998, author = {Zientz, Evelyn and Bongaerts, Johannes and Unden, Gottfried}, title = {Fumarate regulation of gene expression in Escherichia coli by the DcuSR (dcuSR genes) two-component regulatory system}, series = {Journal of bacteriology}, volume = {Vol. 180}, journal = {Journal of bacteriology}, number = {No. 20}, issn = {1098-5530 (E-Journal); 0021-9193 (Print)}, pages = {5421 -- 5425}, year = {1998}, language = {en} } @incollection{ArtmannMeruvuKizildagetal.2018, author = {Artmann, Gerhard and Meruvu, Haritha and Kizildag, Sefa and Temiz Artmann, Ayseg{\"u}l}, title = {Functional Toxicology and Pharmacology Test of Cell Induced Mechanical Tensile Stress in 2D and 3D Tissue Cultures}, series = {Biological, Physical and Technical Basics of Cell Engineering}, booktitle = {Biological, Physical and Technical Basics of Cell Engineering}, editor = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya}, publisher = {Springer}, address = {Singapore}, isbn = {978-981-10-7904-7}, doi = {10.1007/978-981-10-7904-7_7}, pages = {157 -- 192}, year = {2018}, abstract = {Mechanical forces/tensile stresses are critical determinants of cellular growth, differentiation and migration patterns in health and disease. The innovative "CellDrum technology" was designed for measuring mechanical tensile stress of cultured cell monolayers/thin tissue constructs routinely. These are cultivated on very thin silicone membranes in the so-called CellDrum. The cell layers adhere firmly to the membrane and thus transmit the cell forces generated. A CellDrum consists of a cylinder which is sealed from below with a 4 μm thick, biocompatible, functionalized silicone membrane. The weight of cell culture medium bulbs the membrane out downwards. Membrane indentation is measured. When cells contract due to drug action, membrane, cells and medium are lifted upwards. The induced indentation changes allow for lateral drug induced mechanical tension quantification of the micro-tissues. With hiPS-induced (human) Cardiomyocytes (CM) the CellDrum opens new perspectives of individualized cardiac drug testing. Here, monolayers of self-beating hiPS-CMs were grown in CellDrums. Rhythmic contractions of the hiPS-cells induce membrane up-and-down deflections. The recorded cycles allow for single beat amplitude, single beat duration, integration of the single beat amplitude over the beat time and frequency analysis. Dose effects of agonists and antagonists acting on Ca2+ channels were sensitively and highly reproducibly observed. Data were consistent with published reference data as far as they were available. The combination of the CellDrum technology with hiPS-Cardiomyocytes offers a fast, facile and precise system for pharmacological and toxicological studies. It allows new preclinical basic as well as applied research in pharmacolgy and toxicology.}, language = {en} } @article{TippkoetterAlKaidyWollnyetal.2013, author = {Tippk{\"o}tter, Nils and Al-Kaidy, Huschyar and Wollny, Steffen and Ulber, Roland}, title = {Functionalized magnetizable particles for downstream processing in single-use systems}, series = {Chemie Ingenieur Technik}, volume = {85}, journal = {Chemie Ingenieur Technik}, number = {1-2: Special Issue: Single-Use Technology}, publisher = {Wiley}, address = {Weinheim}, doi = {10.1002/cite.201200130}, pages = {76 -- 86}, year = {2013}, abstract = {Biotechnological downstream processing is usually an elaborate procedure, requiring a multitude of unit operations to isolate the target component. Besides the disadvantageous space-time yield, the risks of cross-contaminations and product loss grow fast with the complexity of the isolation procedure. A significant reduction of unit operations can be achieved by application of magnetic particles, especially if these are functionalized with affinity ligands. As magnetic susceptible materials are highly uncommon in biotechnological processes, target binding and selective separation of such particles from fermentation or reactions broths can be done in a single step. Since the magnetizable particles can be produced from iron salts and low priced polymers, a single-use implementation of these systems is highly conceivable. In this article, the principles of magnetizable particles, their synthesis and functionalization are explained. Furthermore, applications in the area of reaction engineering, microfluidics and downstream processing are discussed focusing on established single-use technologies and development potential.}, language = {en} } @misc{EhmkeFingerHojdisetal.2020, author = {Ehmke, Tobias and Finger, Sebastian and Hojdis, Nils and Kurz, Martin and Nawrocka-Herczynska, Monika}, title = {Funkeinheit und Vorrichtung mit einer Funkeinheit}, year = {2020}, abstract = {Dargestellt und beansprucht ist eine Funkeinheit mit einem Funkbauteil, einer elektrisch leitf{\"a}higen Antenne und einem Kunststoffverbindungsmittel. Das Funkbauteil weist einen Antennenanschluss auf. Das Kunststoffverbindungsmittel weist ein erstes Elastomermaterial mit elektrisch leitf{\"a}higem Zusatzmaterial auf, so dass das Kunststoffverbindungsmittel elektrisch leitf{\"a}hig ist. Das Kunststoffverbindungsmittel bildet eine mechanische und elektrisch leitf{\"a}hige Verbindung zwischen dem Antennenanschluss und der Antenne. Weiterhin wird eine Vorrichtung mit einem ein Matrixmaterial mit oder aus einem zweiten Elastomermaterial und einer Funkeinheit beschrieben und beansprucht, wobei die Funkeinheit vollst{\"a}ndig in das Matrixmaterial eingebettet ist. Die Vorrichtung kann insbesondere ein Fahrzeugreifen sein.}, language = {de} } @misc{JerominMang2005, author = {Jeromin, G{\"u}nter Erich and Mang, Thomas}, title = {Funktionalisierte magnetisierbare Partikel : Offenlegungsschrift DE102004005199A1 ; Offenlegungstag: 18.08.2005}, publisher = {Deutsches Patent- und Markenamt}, address = {M{\"u}nchen}, pages = {8 S.}, year = {2005}, language = {de} } @article{FeuerriegelHoffmannWalenziketal.2001, author = {Feuerriegel, Uwe and Hoffmann, Ulrich and Walenzik, C. and K{\"o}gel, J.}, title = {F{\"u}r Scale-up´s und Betriebsmuster, Projekt Trocknungstechnik an der FH Aachen}, series = {CITplus : das Praxismagazin f{\"u}r Verfahrenstechnik und Apparatebau. 4 (2001)}, journal = {CITplus : das Praxismagazin f{\"u}r Verfahrenstechnik und Apparatebau. 4 (2001)}, isbn = {1436-2597}, pages = {24 -- 25}, year = {2001}, language = {de} } @article{MangRoosenAnsorgeetal.2006, author = {Mang, Thomas and Roosen, C. and Ansorge, M. and Leitner, W.}, title = {Gaining pH-control in water/carbon dioxide biphasic systems / Abstract No. 1038 / Roosen, Ch. ; Ansorge, M. ; Mang, Thomas ; Leitner, W. ; Greiner, L.}, series = {Green solvents for processes : Lake Constance, Friedrichshafen, Germany, 8 - 11 October 2006 ; book of abstracts / DECHEMA e.V.}, journal = {Green solvents for processes : Lake Constance, Friedrichshafen, Germany, 8 - 11 October 2006 ; book of abstracts / DECHEMA e.V.}, publisher = {DECHEMA}, address = {Frankfurt am Main}, pages = {145 S.}, year = {2006}, language = {en} } @article{MangRoosenAnsorgeSchumacheretal.2007, author = {Mang, Thomas and Roosen, Christoph and Ansorge-Schumacher, Marion and Leitner, Walter}, title = {Gaining pH-control in water/carbon dioxide biphasic systems / Roosen, Christoph ; Ansorge-Schumacher, Marion ; Mang, Thomas ; Leitner, Walter ; Greiner, Lasse}, series = {Green Chemistry. 9 (2007)}, journal = {Green Chemistry. 9 (2007)}, isbn = {1463-9262}, pages = {455 -- 458}, year = {2007}, language = {en} } @article{SchererGaeggelerJostetal.1992, author = {Scherer, Ulrich W. and G{\"a}ggeler, H. W. and Jost, D. T. and Kovacs, J.}, title = {Gas Phase Chromatography Experiments with Bromides of Tantalum and Element 105 / H.W. G{\"a}ggeler, D.T. Jost, J. Kovacs, U.W. Scherer, A. Weber, D. Vermeulen, A. T{\"u}rler, K.E. Gregorich, R.A. Henderson, K.R. Czerwinski, B. Kadkhodayan, D.M. Lee, M. Nurmia, D.}, series = {Radiochimica Acta. 57 (1992)}, journal = {Radiochimica Acta. 57 (1992)}, isbn = {0033-8230}, pages = {93 -- 100}, year = {1992}, language = {en} }