@article{BreuerPilasGuthmannetal.2019,
  author    = {Breuer, Lars and Pilas, Johanna and Guthmann, Eric and Sch{\"o}ning, Michael Josef and Thoelen, Ronald and Wagner, Torsten},
  title     = {Towards light-addressable flow control: responsive hydrogels with incorporated graphene oxide as laser-driven actuator structures within microfluidic channels},
  series = {Sensor and Actuators B: Chemical},
  volume    = {288},
  journal   = {Sensor and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2019.02.086},
  pages     = {579 -- 585},
  year      = {2019},
  language  = {en}
}
@article{ArreolaKeusgenSchoening2019,
  author    = {Arreola, Julio and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Toward an immobilization method for spore-based biosensors in oxidative environment},
  series = {Electrochimica Acta},
  volume    = {302},
  journal   = {Electrochimica Acta},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.electacta.2019.01.148},
  pages     = {394 -- 401},
  year      = {2019},
  language  = {en}
}
@article{BronderPoghossianJessingetal.2019,
  author    = {Bronder, Thomas and Poghossian, Arshak and Jessing, Max P. and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Surface regeneration and reusability of label-free DNA biosensors based on weak polyelectrolyte-modified capacitive field-effect structures},
  series = {Biosensors and Bioelectronics},
  volume    = {126},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2018.11.019},
  pages     = {510 -- 517},
  year      = {2019},
  language  = {en}
}
@article{CornelisGivanoudiYongabietal.2019,
  author    = {Cornelis, Peter and Givanoudi, Stella and Yongabi, Derick and Iken, Heiko and Duw{\´e}, Sam and Deschaume, Olivier and Robbens, Johan and Dedecker, Peter and Bartic, Carmen and W{\"u}bbenhorst, Michael and Sch{\"o}ning, Michael Josef and Heyndrickx, Marc and Wagner, Patrick},
  title     = {Sensitive and specific detection of E. coli using biomimetic receptors in combination with a modified heat-transfer method},
  series = {Biosensors and Bioelectronics},
  volume    = {136},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2019.04.026},
  pages     = {97 -- 105},
  year      = {2019},
  language  = {en}
}
@article{AchtsnichtNeuendorfFassbenderetal.2019,
  author    = {Achtsnicht, Stefan and Neuendorf, Christian and Faßbender, Tobias and N{\"o}lke, Greta and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim and Schr{\"o}per, Florian},
  title     = {Sensitive and rapid detection of cholera toxin subunit B using magnetic frequency mixing detection},
  series = {Plos One},
  volume    = {14},
  journal   = {Plos One},
  number    = {7},
  publisher = {Plos},
  address   = {San Francisco},
  issn      = {1932-6203},
  doi       = {10.1371/journal.pone.0219356},
  pages     = {e0219356},
  year      = {2019},
  abstract  = {Cholera is a life-threatening disease caused by the cholera toxin (CT) as produced by some Vibrio cholerae serogroups. In this research we present a method which directly detects the toxin's B subunit (CTB) in drinking water. For this purpose we performed a magnetic sandwich immunoassay inside a 3D immunofiltration column. We used two different commercially available antibodies to capture CTB and for binding to superparamagnetic beads. ELISA experiments were performed to select the antibody combination. The beads act as labels for the magnetic frequency mixing detection technique. We show that the limit of detection depends on the type of magnetic beads. A nonlinear Hill curve was fitted to the calibration measurements by means of a custom-written python software. We achieved a sensitive and rapid detection of CTB within a broad concentration range from 0.2 ng/ml to more than 700 ng/ml.},
  language  = {en}
}
@article{PilasSelmerKeusgenetal.2019,
  author    = {Pilas, Johanna and Selmer, Thorsten and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Screen-printed carbon electrodes modified with graphene oxide for the design of a reagent-free NAD+-dependent biosensor array},
  series = {Analytical Chemistry},
  volume    = {91},
  journal   = {Analytical Chemistry},
  number    = {23},
  publisher = {ACS Publications},
  address   = {Washington},
  doi       = {10.1021/acs.analchem.9b04481},
  pages     = {15293 -- 15299},
  year      = {2019},
  language  = {en}
}
@article{PoghossianGeisslerSchoening2019,
  author    = {Poghossian, Arshak and Geissler, Hanno and Sch{\"o}ning, Michael Josef},
  title     = {Rapid methods and sensors for milk quality monitoring and spoilage detection},
  series = {Biosensors and Bioelectronics},
  volume    = {140},
  journal   = {Biosensors and Bioelectronics},
  number    = {Article 111272},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2019.04.040},
  year      = {2019},
  language  = {en}
}
@article{DantismRoehlenSelmeretal.2019,
  author    = {Dantism, Shahriar and R{\"o}hlen, Desiree and Selmer, Thorsten and Wagner, Torsten and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Quantitative differential monitoring of the metabolic activity of Corynebacterium glutamicum cultures utilizing a light-addressable potentiometric sensor system},
  series = {Biosensors and Bioelectronics},
  volume    = {139},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.bios.2019.111332},
  pages     = {Artikel 111332},
  year      = {2019},
  language  = {en}
}
@article{KarschuckFilipovBollellaetal.2019,
  author    = {Karschuck, T. L. and Filipov, Y. and Bollella, P. and Sch{\"o}ning, Michael Josef and Katz, E.},
  title     = {Not-XOR (NXOR) logic gate based on an enzyme-catalyzed reaction},
  series = {International Journal of Unconventional Computing},
  volume    = {14},
  journal   = {International Journal of Unconventional Computing},
  number    = {3-4},
  publisher = {Old City Publishing},
  address   = {Philadelphia},
  issn      = {1548-7199},
  pages     = {235 -- 242},
  year      = {2019},
  abstract  = {Enzyme-catalyzed reactions have been designed to mimic various Boolean logic gates in the general framework of unconventional biomolecular computing. While some of the logic gates, particularly OR, AND, are easy to realize with biocatalytic reactions and have been reported in numerous publications, some other, like NXOR, are very challenging and have not been realized yet with enzyme reactions. The paper reports on a novel approach to mimicking the NXOR logic gate using the bell-shaped enzyme activity dependent on pH values. Shifting pH from the optimum value to the acidic or basic values by using acid or base inputs (meaning 1,0 and 0,1 inputs) inhibits the enzyme reaction, while keeping the optimum pH (assuming 0,0 and 1,1 input combinations) preserves a high enzyme activity. The challenging part of the present approach is the selection of an enzyme with a well-demonstrated bell-shape activity dependence on the pH value. While many enzymes can satisfy this condition, we selected pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenase as this enzyme has the optimum pH center-located on the pH scale allowing the enzyme activity change by the acidic and basic pH shift from the optimum value corresponding to the highest activity. The present NXOR gate is added to the biomolecular "toolbox" as a new example of Boolean logic gates based on enzyme reactions.},
  language  = {en}
}
@article{AchtsnichtPourshahidiOffenhaeusseretal.2019,
  author    = {Achtsnicht, Stefan and Pourshahidi, Ali Mohammad and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim},
  title     = {Multiplex detection of different magnetic beads using frequency scanning in magnetic frequency mixing technique},
  series = {Sensors},
  volume    = {19},
  journal   = {Sensors},
  number    = {11},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s19112599},
  pages     = {13 Seiten},
  year      = {2019},
  abstract  = {In modern bioanalytical methods, it is often desired to detect several targets in one sample within one measurement. Immunological methods including those that use superparamagnetic beads are an important group of techniques for these applications. The goal of this work is to investigate the feasibility of simultaneously detecting different superparamagnetic beads acting as markers using the magnetic frequency mixing technique. The frequency of the magnetic excitation field is scanned while the lower driving frequency is kept constant. Due to the particles' nonlinear magnetization, mixing frequencies are generated. To record their amplitude and phase information, a direct digitization of the pickup-coil's signal with subsequent Fast Fourier Transformation is performed. By synchronizing both magnetic beads using frequency scanning in magnetic frequency mixing technique magnetic fields, a stable phase information is gained. In this research, it is shown that the amplitude of the dominant mixing component is proportional to the amount of superparamagnetic beads inside a sample. Additionally, it is shown that the phase does not show this behaviour. Excitation frequency scans of different bead types were performed, showing different phases, without correlation to their diverse amplitudes. Two commercially available beads were selected and a determination of their amount in a mixture is performed as a demonstration for multiplex measurements.},
  language  = {en}
}