@article{DantismRoehlenWagneretal.2019, author = {Dantism, Shahriar and R{\"o}hlen, Desiree and Wagner, Torsten and Wagner, P. and Sch{\"o}ning, Michael Josef}, title = {A LAPS-based differential sensor for parallelized metabolism monitoring of various bacteria}, series = {Sensors}, volume = {19}, journal = {Sensors}, number = {21}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s19214692}, pages = {Artikel 4692}, year = {2019}, abstract = {Monitoring the cellular metabolism of bacteria in (bio)fermentation processes is crucial to control and steer them, and to prevent undesired disturbances linked to metabolically inactive microorganisms. In this context, cell-based biosensors can play an important role to improve the quality and increase the yield of such processes. This work describes the simultaneous analysis of the metabolic behavior of three different types of bacteria by means of a differential light-addressable potentiometric sensor (LAPS) set-up. The study includes Lactobacillus brevis, Corynebacterium glutamicum, and Escherichia coli, which are often applied in fermentation processes in bioreactors. Differential measurements were carried out to compensate undesirable influences such as sensor signal drift, and pH value variation during the measurements. Furthermore, calibration curves of the cellular metabolism were established as a function of the glucose concentration or cell number variation with all three model microorganisms. In this context, simultaneous (bio)sensing with the multi-organism LAPS-based set-up can open new possibilities for a cost-effective, rapid detection of the extracellular acidification of bacteria on a single sensor chip. It can be applied to evaluate the metabolic response of bacteria populations in a (bio)fermentation process, for instance, in the biogas fermentation process.}, language = {en} } @article{KarschuckFilipovBollellaetal.2019, author = {Karschuck, T. L. and Filipov, Y. and Bollella, P. and Sch{\"o}ning, Michael Josef and Katz, E.}, title = {Not-XOR (NXOR) logic gate based on an enzyme-catalyzed reaction}, series = {International Journal of Unconventional Computing}, volume = {14}, journal = {International Journal of Unconventional Computing}, number = {3-4}, publisher = {Old City Publishing}, address = {Philadelphia}, issn = {1548-7199}, pages = {235 -- 242}, year = {2019}, abstract = {Enzyme-catalyzed reactions have been designed to mimic various Boolean logic gates in the general framework of unconventional biomolecular computing. While some of the logic gates, particularly OR, AND, are easy to realize with biocatalytic reactions and have been reported in numerous publications, some other, like NXOR, are very challenging and have not been realized yet with enzyme reactions. The paper reports on a novel approach to mimicking the NXOR logic gate using the bell-shaped enzyme activity dependent on pH values. Shifting pH from the optimum value to the acidic or basic values by using acid or base inputs (meaning 1,0 and 0,1 inputs) inhibits the enzyme reaction, while keeping the optimum pH (assuming 0,0 and 1,1 input combinations) preserves a high enzyme activity. The challenging part of the present approach is the selection of an enzyme with a well-demonstrated bell-shape activity dependence on the pH value. While many enzymes can satisfy this condition, we selected pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenase as this enzyme has the optimum pH center-located on the pH scale allowing the enzyme activity change by the acidic and basic pH shift from the optimum value corresponding to the highest activity. The present NXOR gate is added to the biomolecular "toolbox" as a new example of Boolean logic gates based on enzyme reactions.}, language = {en} } @phdthesis{Engelmann2019, author = {Engelmann, Ulrich M.}, title = {Assessing magnetic fluid hyperthermia : magnetic relaxation simulation, modeling of nanoparticle uptake inside pancreatic tumor cells and in vitro efficacy}, publisher = {Infinite Science Publishing}, address = {L{\"u}beck}, isbn = {978-3-945954-58-4}, year = {2019}, language = {en} } @misc{Engelmann2019, author = {Engelmann, Ulrich M.}, title = {Gespr{\"a}chsf{\"u}hrungskompetenzen f{\"u}r Naturwissenschaftler und Ingenieure. Maßnahmen zur F{\"o}rderung und curricularen Verankerung von Gespr{\"a}chsf{\"u}hrungskompetenzen an Fachhochschulen}, publisher = {Deutsche Gesellschaft f{\"u}r Sprechwissenschaft und Sprecherziehung (DGSS e.V.)}, address = {Aachen}, doi = {10.13140/RG.2.2.34026.98248}, pages = {121 Seiten}, year = {2019}, language = {de} } @article{FingerBilBraun2019, author = {Finger, Felix and Bil, Cees and Braun, Carsten}, title = {Initial Sizing Methodology for Hybrid-Electric General Aviation Aircraft}, series = {Journal of Aircraft}, volume = {57}, journal = {Journal of Aircraft}, number = {2}, issn = {1533-3868}, doi = {10.2514/1.C035428}, pages = {245 -- 255}, year = {2019}, language = {en} } @inproceedings{KerpenSchooneesSchlurmannetal.2019, author = {Kerpen, Nils B. and Schoonees, Talia and Schlurmann, Torsten and Valero, Daniel and Bung, Daniel Bernhard}, title = {waveSTEPS - Wellenauf- und Wellen{\"u}berlauf an getreppten Deckwerken}, series = {24. KFKI-Seminar 2019, 21.11.2019}, booktitle = {24. KFKI-Seminar 2019, 21.11.2019}, pages = {2 Seiten}, year = {2019}, language = {de} } @book{Pieper2019, author = {Pieper, Martin}, title = {Quantenmechanik : Einf{\"u}hrung in die mathematische Formulierung}, publisher = {Springer Spektrum}, address = {Wiesbaden}, isbn = {978-3-658-28329-2}, doi = {10.1007/978-3-658-28329-2}, year = {2019}, language = {de} } @article{WilbringEnning2019, author = {Wilbring, Daniela and Enning, Manfred}, title = {Stromversorgung auf G{\"u}terwagen - Aktuelle Bem{\"u}hungen zur Standardisierung}, series = {ETR - Eisenbahntechnische Rundschau}, volume = {68}, journal = {ETR - Eisenbahntechnische Rundschau}, number = {11}, publisher = {DVV Media Group}, address = {Hamburg}, issn = {0013-2845}, pages = {64 -- 67}, year = {2019}, language = {de} } @inproceedings{LuftGebhardtBalc2019, author = {Luft, Angela and Gebhardt, Andreas and Balc, Nicolae}, title = {Challenges of additive manufacturing in production systems}, series = {Modern technologies in manufacturing (MTeM 2019)}, volume = {299}, booktitle = {Modern technologies in manufacturing (MTeM 2019)}, number = {Article 01003}, doi = {10.1051/matecconf/201929901003}, pages = {6 Seiten}, year = {2019}, language = {en} } @inproceedings{AbbasThurnKessleretal.2019, author = {Abbas, Karim and Thurn, Laura and Kessler, Julia and Eichler, Fabian}, title = {Basic research of the consideration of additive manufactured lattice structures under thermoand fluid dynamic loads}, series = {Modern technologies in manufacturing (MTeM 2019)}, volume = {299}, booktitle = {Modern technologies in manufacturing (MTeM 2019)}, number = {Article 01009}, doi = {10.1051/matecconf/201929901009}, pages = {8 Seiten}, year = {2019}, language = {en} }