@article{AchtsnichtToedterNiehuesetal.2019, author = {Achtsnicht, Stefan and T{\"o}dter, Julia and Niehues, Julia and Tel{\"o}ken, Matthias and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim and Schr{\"o}per, Florian}, title = {3D printed modular immunofiltration columns for frequency mixing-based multiplex magnetic immunodetection}, series = {Sensors}, volume = {19}, journal = {Sensors}, number = {1}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s19010148}, pages = {15 Seiten}, year = {2019}, abstract = {For performing point-of-care molecular diagnostics, magnetic immunoassays constitute a promising alternative to established enzyme-linked immunosorbent assays (ELISA) because they are fast, robust and sensitive. Simultaneous detection of multiple biomolecular targets from one body fluid sample is desired. The aim of this work is to show that multiplex magnetic immunodetection based on magnetic frequency mixing by means of modular immunofiltration columns prepared for different targets is feasible. By calculations of the magnetic response signal, the required spacing between the modules was determined. Immunofiltration columns were manufactured by 3D printing and antibody immobilization was performed in a batch approach. It was shown experimentally that two different target molecules in a sample solution could be individually detected in a single assaying step with magnetic measurements of the corresponding immobilization filters. The arrangement order of the filters and of a negative control did not influence the results. Thus, a simple and reliable approach to multi-target magnetic immunodetection was demonstrated.}, language = {en} } @book{KrauseUlkeMartinetal.2019, author = {Krause, Thomas and Ulke, Bernd and Martin, Joachim and Lemke, J{\"o}rg and Sparla, Peter and Streit, Wilfried}, title = {{\"U}bungsaufgaben und Berechnungen f{\"u}r den Baubetrieb: Klausurvorbereitung mit ausf{\"u}hrlichen L{\"o}sungen}, editor = {Krause, Thomas and Ulke, Bernd}, edition = {3. Auflage}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-23126-2 (Print) 978-3-658-23127-9 (Online)}, pages = {XI, 347 Seiten ; Illustrationen}, year = {2019}, language = {de} } @incollection{Kurz2019, author = {Kurz, Melanie}, title = {Betrifft Design : von historischen Zukunftsperspektiven zu gegenw{\"a}rtigen Vergangenheitssehns{\"u}chten}, series = {Positionen des Neuen : Zukunft im Design}, booktitle = {Positionen des Neuen : Zukunft im Design}, publisher = {avedition}, address = {Stuttgart}, isbn = {978-3-89986-301-7}, pages = {136 -- 144}, year = {2019}, language = {de} }