@article{PoghossianSchoening2014,
  author    = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Label-free sensing of biomolecules with field-effect devices for clinical applications},
  series = {Electroanalysis},
  volume    = {26},
  journal   = {Electroanalysis},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-4109 (E-Journal); 1040-0397 (Print)},
  doi       = {10.1002/elan.201400073},
  pages     = {1197 -- 1213},
  year      = {2014},
  abstract  = {Among the variety of transducer concepts proposed for label-free detection of biomolecules, the semiconductor field-effect device (FED) is one of the most attractive platforms. As medical techniques continue to progress towards diagnostic and therapies based on biomarkers, the ability of FEDs for a label-free, fast and real-time detection of multiple pathogenic and physiologically relevant molecules with high specificity and sensitivity offers very promising prospects for their application in point-of-care and personalized medicine for an early diagnosis and treatment of diseases. The presented paper reviews recent advances and current trends in research and development of different FEDs for label-free, direct electrical detection of charged biomolecules by their intrinsic molecular charge. The authors are mainly focusing on the detection of the DNA hybridization event, antibody-antigen affinity reaction as well as clinically relevant biomolecules such as cardiac and cancer biomarkers.},
  language  = {en}
}
@article{SiqueiraWernerBaeckeretal.2009,
  author    = {Siqueira, Jose R. and Werner, Frederik and B{\"a}cker, Matthias and Poghossian, Arshak and Zucolotto, Valtencir and Oliveira, Osvaldo N. Jr. and Sch{\"o}ning, Michael Josef},
  title     = {Layer-by-Layer Assembly of Carbon Nanotubes Incorporated in Light-Addressable Potentiometric Sensors},
  series = {Journal of Physical Chemistry C. 113 (2009), H. 33},
  journal   = {Journal of Physical Chemistry C. 113 (2009), H. 33},
  publisher = {American Chemical Society},
  address   = {Washington, DC},
  isbn      = {1932-7455},
  pages     = {14765 -- 14770},
  year      = {2009},
  language  = {en}
}
@incollection{SchoeningWagnerPoghossianetal.2018,
  author    = {Sch{\"o}ning, Michael Josef and Wagner, Torsten and Poghossian, Arshak and Miyamoto, K.I. and Werner, C.F. and Krause, S. and Yoshinobu, T.},
  title     = {Light-addressable potentiometric sensors for (bio-)chemical sensing and imaging},
  series = {Encyclopedia of Interfacial Chemistry: Surface Science and Electrochemistry. Vol. 7},
  booktitle = {Encyclopedia of Interfacial Chemistry: Surface Science and Electrochemistry. Vol. 7},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {9780128097397},
  pages     = {295 -- 308},
  year      = {2018},
  language  = {en}
}
@article{YoshinobuMiyamotoWerneretal.2017,
  author    = {Yoshinobu, Tatsuo and Miyamoto, Ko-ichiro and Werner, Frederik and Poghossian, Arshak and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Light-addressable potentiometric sensors for quantitative spatial imaging of chemical species},
  series = {Annual Review of Analytical Chemistry},
  volume    = {10},
  journal   = {Annual Review of Analytical Chemistry},
  publisher = {Annual Reviews},
  address   = {Palo Alto, Calif.},
  issn      = {1936-1327},
  doi       = {10.1146/annurev-anchem-061516-045158},
  pages     = {225 -- 246},
  year      = {2017},
  abstract  = {A light-addressable potentiometric sensor (LAPS) is a semiconductor-based chemical sensor, in which a measurement site on the sensing surface is defined by illumination. This light addressability can be applied to visualize the spatial distribution of pH or the concentration of a specific chemical species, with potential applications in the fields of chemistry, materials science, biology, and medicine. In this review, the features of this chemical imaging sensor technology are compared with those of other technologies. Instrumentation, principles of operation, and various measurement modes of chemical imaging sensor systems are described. The review discusses and summarizes state-of-the-art technologies, especially with regard to the spatial resolution and measurement speed; for example, a high spatial resolution in a submicron range and a readout speed in the range of several tens of thousands of pixels per second have been achieved with the LAPS. The possibility of combining this technology with microfluidic devices and other potential future developments are discussed.},
  language  = {en}
}
@article{GasparyanPoghossianVitusevichetal.2009,
  author    = {Gasparyan, F. V. and Poghossian, Arshak and Vitusevich, S. A. and Petrychuk, M. V. and Sydoruk, V. A. and Surmalyan, A. V. and Siqueira, J. R. and Oliveira, O. N. and Offenh{\"a}usser, A. and Sch{\"o}ning, Michael Josef},
  title     = {Low Frequency Noise In Electrolyte-Gate Field-Effect Devices Functionalized With Dendrimer/Carbon-Nanotube Multilayers},
  series = {Noise and fluctuations : 20th International Conference on Noise and Fluctuations, ICNF 2009, Pisa, Italy, 14 - 19 June 2009 / ed. Massimo Macucci; Giovanni Basso},
  journal   = {Noise and fluctuations : 20th International Conference on Noise and Fluctuations, ICNF 2009, Pisa, Italy, 14 - 19 June 2009 / ed. Massimo Macucci; Giovanni Basso},
  publisher = {American Inst. of Physics},
  address   = {Melville, NY},
  isbn      = {9780735406650},
  pages     = {133 -- 136},
  year      = {2009},
  language  = {en}
}
@article{GasparyanPoghossianVitusevichetal.2011,
  author    = {Gasparyan, Ferdinand V. and Poghossian, Arshak and Vitusevich, Svetlana A. and Petrychuk, Mykhaylo V. and Sydoruk, Viktor A. and Siqueira, Jos{\´e} R. Jr. and Oliveira, Osvaldo N. Jr. and Offenh{\"a}usser, Andreas and Sch{\"o}ning, Michael Josef},
  title     = {Low-Frequency Noise in Field-Effect Devices Functionalized With Dendrimer/Carbon-Nanotube Multilayers},
  series = {IEEE Sensors Journal. 11 (2011), H. 1},
  journal   = {IEEE Sensors Journal. 11 (2011), H. 1},
  publisher = {IEEE},
  address   = {New York},
  isbn      = {1530-437X},
  pages     = {142 -- 149},
  year      = {2011},
  language  = {en}
}
@article{SchoeningAbouzarPoghossianetal.2007,
  author    = {Sch{\"o}ning, Michael Josef and Abouzar, Maryam H. and Poghossian, Arshak and Han, Yinhua and Offenh{\"a}usser, Andreas and Ingebrandt, Sven},
  title     = {Markierungsfreie DNA-Detektion mit Silizium-Feldeffekt-Sensoren - Messeffekte oder Artefakte?},
  series = {tm - Technisches Messen . 74 (2007), H. 9},
  journal   = {tm - Technisches Messen . 74 (2007), H. 9},
  isbn      = {0171-8096},
  pages     = {466 -- 476},
  year      = {2007},
  language  = {de}
}
@inproceedings{SchoeningAbouzarHanetal.2006,
  author    = {Sch{\"o}ning, Michael Josef and Abouzar, Maryam H. and Han, Y. and Ingebrandt, S. and Offenh{\"a}usser, A. and Poghossian, Arshak},
  title     = {Markierungsfreie DNA-Detektion mit Silizium-Feldeffektsensoren - Messeffekte oder Artefakte?},
  series = {Sensoren und Mess-Systeme 2006 : Vortr{\"a}ge der 13. ITG/GMA-Fachtagung vom 13. bis 14.3.2006 in Freiburg/Breisgau},
  booktitle = {Sensoren und Mess-Systeme 2006 : Vortr{\"a}ge der 13. ITG/GMA-Fachtagung vom 13. bis 14.3.2006 in Freiburg/Breisgau},
  publisher = {VDE Verl.},
  address   = {Berlin},
  isbn      = {3-8007-2939-3},
  pages     = {443 -- 446},
  year      = {2006},
  language  = {de}
}
@article{SchoeningPoghossianSchultze2003,
  author    = {Sch{\"o}ning, Michael Josef and Poghossian, Arshak and Schultze, Joachim W.},
  title     = {Measuring seven parameters by two ISFET modules in a microcell set-up},
  series = {Int. Journal of Computational Engineering Science. 4 (2003), H. 2},
  journal   = {Int. Journal of Computational Engineering Science. 4 (2003), H. 2},
  isbn      = {1465-8763},
  pages     = {257 -- 260},
  year      = {2003},
  language  = {en}
}
@article{HuckSchiffelsHerreraetal.2013,
  author    = {Huck, Christina and Schiffels, Johannes and Herrera, Cony N. and Schelden, Maximilian and Selmer, Thorsten and Poghossian, Arshak and Baumann, Marcus and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Metabolic responses of Escherichia coli upon glucose pulses captured by a capacitive field-effect sensor},
  series = {Physica Status Solidi (A)},
  volume    = {210},
  journal   = {Physica Status Solidi (A)},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0031-8965},
  doi       = {10.1002/pssa.201200900},
  pages     = {926 -- 931},
  year      = {2013},
  abstract  = {Living cells are complex biological systems transforming metabolites taken up from the surrounding medium. Monitoring the responses of such cells to certain substrate concentrations is a challenging task and offers possibilities to gain insight into the vitality of a community influenced by the growth environment. Cell-based sensors represent a promising platform for monitoring the metabolic activity and thus, the "welfare" of relevant organisms. In the present study, metabolic responses of the model bacterium Escherichia coli in suspension, layered onto a capacitive field-effect structure, were examined to pulses of glucose in the concentration range between 0.05 and 2 mM. It was found that acidification of the surrounding medium takes place immediately after glucose addition and follows Michaelis-Menten kinetic behavior as a function of the glucose concentration. In future, the presented setup can, therefore, be used to study substrate specificities on the enzymatic level and may as well be used to perform investigations of more complex metabolic responses. Conclusions and perspectives highlighting this system are discussed.},
  language  = {en}
}