@article{LeschingerBirgelHackletal.2019, author = {Leschinger, Tim and Birgel, Stefan and Hackl, Michael and Staat, Manfred and M{\"u}ller, Lars Peter and Wegmann, Kilian}, title = {A musculoskeletal shoulder simulation of moment arms and joint reaction forces after medialization of the supraspinatus footprint in rotator cuff repair}, series = {Computer Methods in Biomechanics and Biomedical Engineering}, journal = {Computer Methods in Biomechanics and Biomedical Engineering}, number = {Early view}, publisher = {Taylor \& Francis}, address = {London}, doi = {10.1080/10255842.2019.1572749}, year = {2019}, language = {en} } @article{DietzelWeberPorschenetal.1976, author = {Dietzel, F. and Weber, Hans-Joachim and Porschen, W. and Feinendegen, L. E.}, title = {Zur W{\"a}rmeempfindlichkeit von oxischen und hypoxischen Zellen in einem Tumor}, series = {Naturwissenschaften}, volume = {63}, journal = {Naturwissenschaften}, number = {12}, publisher = {Springer}, address = {Heidelberg}, issn = {0028-1042}, doi = {10.1007/BF00622808}, pages = {585 -- 586}, year = {1976}, language = {de} } @article{Timme2023, author = {Timme, Michael}, title = {Die Erbringung einer Leistung in der irrigen Vorstellung einer Bestellung (Zu BGH, MDR 2023, 1439)}, series = {Monatsschrift f{\"u}r Deutsches Recht}, volume = {77}, journal = {Monatsschrift f{\"u}r Deutsches Recht}, number = {24}, publisher = {Verlag Dr. Otto Schmidt}, address = {K{\"o}ln}, issn = {2194-4202 (online)}, doi = {10.9785/mdtr-2023-772402}, pages = {R293 -- R296}, year = {2023}, language = {de} } @inproceedings{KuperjansSchreiberDetermannetal.1998, author = {Kuperjans, Isabel and Schreiber, M. and Determann, L. and Schreiber, R.}, title = {Entscheidungsunterst{\"u}tzung bei der Gestaltung der betrieblichen Energieversorgung und -nutzung}, series = {Innovationen bei der rationellen Energieanwendung : neue Chancen f{\"u}r die Wirtschaft ; Tagung Dortmund, 3. und 4. M{\"a}rz 1998. - (VDI-Berichte ; 1385)}, booktitle = {Innovationen bei der rationellen Energieanwendung : neue Chancen f{\"u}r die Wirtschaft ; Tagung Dortmund, 3. und 4. M{\"a}rz 1998. - (VDI-Berichte ; 1385)}, publisher = {VDI-Verl.}, address = {D{\"u}sseldorf}, isbn = {3-18-091385-1}, pages = {79 -- 94}, year = {1998}, language = {de} } @inproceedings{Rosenkranz1993, author = {Rosenkranz, Josef}, title = {Verbesserung der Laufruhe des Verbrennungsmotors durch abgestimmte qualit{\"a}tssteigernde Maßnahmen beim Auswuchten des Kurbeltriebs}, series = {Antriebstechnisches Kolloquium '93 / Industrieentwicklungen und Forschungsergebnisse f{\"u}r die Maschinen{\"u}berwachung und die Konstruktion in der Antriebstechnik. - (Reihe IME-Leitfaden)}, booktitle = {Antriebstechnisches Kolloquium '93 / Industrieentwicklungen und Forschungsergebnisse f{\"u}r die Maschinen{\"u}berwachung und die Konstruktion in der Antriebstechnik. - (Reihe IME-Leitfaden)}, publisher = {Verl. T{\"U}V Rheinland}, address = {K{\"o}ln}, isbn = {3-8249-0139-0}, pages = {176 -- 199}, year = {1993}, language = {de} } @incollection{AugensteinGuerzenichKuperjansetal.2004, author = {Augenstein, Eckardt and G{\"u}rzenich, D. and Kuperjans, Isabel and Wrobel, G.}, title = {TOP-Energy : softwaregest{\"u}tzte Analyse und Optimierung industrieller Energieversorgungssysteme}, series = {Entwicklungslinien der Energietechnik 2004}, booktitle = {Entwicklungslinien der Energietechnik 2004}, edition = {CD-ROM-Ausg.}, publisher = {VDI}, address = {D{\"u}sseldorf}, year = {2004}, language = {de} } @misc{SchumannRoginSchneideretal.2012, author = {Schumann, C. and Rogin, S. and Schneider, H. and Oster, J. and Tippk{\"o}tter, Nils and Kampeis, P.}, title = {Steuerung von HGMS-Prozessen mittels Durchflusszytometrie}, series = {Chemie Ingenieur Technik}, volume = {84}, journal = {Chemie Ingenieur Technik}, number = {8}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201250125}, pages = {1370}, year = {2012}, abstract = {Die Hochgradientenmagnetseparation (HGMS) ist eine Methode zur Aufreinigung von biopharmazeutischen Produkten. Mit dieser Methode l{\"a}sst sich in nur einem Schritt eine Fest/Fest/Fl{\"u}ssig-Trennung erzielen, was zu einer erheblichen Zeit- und Kostenersparnis im Downstreaming f{\"u}hrt. Dennoch steht ihr industrieller Einsatz noch aus, was u. a. am Mangel an Analysenmethoden liegt, um die HGMS quantifizierbar zu machen. Gerade in der Pharmaproduktion werden Prozesse gebraucht, die gem{\"a}ß den einschl{\"a}gigen Vorschriften (cGMP) validiert und deren verfahrenstechnische Anlagenteile qualifiziert werden k{\"o}nnen. Die Schwierigkeit ist die Messung der magnetischen Mikrosorbentien in der Suspension, in der auch Zellen oder Zelltr{\"u}mmer vorliegen. Im Rahmen eines Forschungsprojektes im „Zentralen Innovationsprogramm Mittelstand" des BMWi wurden verschiedene Analysenmethoden untersucht. Die Durchflusszytometrie erm{\"o}glicht eine Charakterisierung von Partikeln und eine simultane quantitative Messung. Durch die multiparametrige Messung kann zwischen Zellen, Zelltr{\"u}mmern und Magnetpartikeln unterschieden werden. Die At-line-Einbindung des Durchflusszytometers ist durch den Einsatz einer externen Pumpe m{\"o}glich. {\"U}ber eine automatisierte Messwertanalyse kann der HGMS-Prozess mittels der Durchflusszytometrie gesteuert werden.}, language = {de} } @inproceedings{EngelThieringerTippkoetter2016, author = {Engel, Mareike and Thieringer, Julia and Tippk{\"o}tter, Nils}, title = {Linking bioprocess engineering and electrochemistry for sustainable biofuel production}, series = {Young Researchers Symposium, YRS 2016. Proceedings}, booktitle = {Young Researchers Symposium, YRS 2016. Proceedings}, publisher = {Fraunhofer Verlag}, address = {Karlsruhe}, pages = {49 -- 53}, year = {2016}, abstract = {Electromicrobial engineering is an emerging, highly interdisciplinary research area linking bioprocesses with electrochemistry. In this work, microbial electrosynthesis (MES) of biobutanol is carried out during acetone-butanol-ethanol (ABE) fermentations with Clostridium acetobutylicum. A constant electric potential of -600mV (vs. Ag/AgCl) with simultaneous addition of the soluble redox mediator neutral red is used in order to study the electron transfer between the working electrode and the bacterial cells. The results show an earlier initiation of solvent production for all fermentations with applied potential compared to the conventional ABE fermentation. The f inal butanol concentration can be more than doubled by the application of a negative potential combined with addition of neutral red. Moreover a higher biofilm formation on the working electrode compared to control cultivations has been observed. In contrast to previous studies, our results also indicate that direct electron transfer (DET) might be possible with C. acetobutylicum. The presented results make microbial butanol production economically attractive and therefore support the development of sustainable production processes in the chemical industry aspired by the "Centre for resource-efficient chemistry and raw material change" as well as the the project "NanoKat" working on nanostructured catalysts in Kaiserslautern.}, language = {en} } @article{HueningHeuermannWacheetal.2018, author = {H{\"u}ning, Felix and Heuermann, Holger and Wache, Franz-Josef and Jajo, Rami Audisho}, title = {A new wireless sensor interface using dual-mode radio}, series = {Journal of Sensors and Sensor Systems : JSSS}, volume = {Volume 7}, journal = {Journal of Sensors and Sensor Systems : JSSS}, number = {2}, publisher = {Copernicus Publ.}, address = {G{\"o}ttingen}, doi = {10.5194/jsss-7-507-2018}, pages = {507 -- 515}, year = {2018}, abstract = {The integration of sensors is one of the major tasks in embedded, control and "internet of things" (IoT) applications. For the integration mainly digital interfaces are used, starting from rather simple pulse-width modulation (PWM) interface to more complex interfaces like CAN (Controller Area Network). Even though these interfaces are tethered by definition, a wireless realization is highly welcome in many applications to reduce cable and connector cost, increase the flexibility and realize new emerging applications like wireless control systems. Currently used wireless solutions like Bluetooth, WirelessHART or IO-Link Wireless use dedicated communication standards and corresponding higher protocol layers to realize the wireless communication. Due to the complexity of the communication and the protocol handling, additional latency and jitter are introduced to the data communication that can meet the requirements for many applications. Even though tunnelling of other bus data like CAN data is generally also possible the latency and jitter prevent the tunnelling from being transparent for the bus system. Therefore a new basic technology based on dual-mode radio is used to realize a wireless communication on the physical layer only, enabling a reliable and real-time data transfer. As this system operates on the physical layer it is independent of any higher layers of the OSI (open systems interconnection) model. Hence it can be used for several different communication systems to replace the tethered physical layer. A prototype is developed and tested for real-time wireless PWM, SENT (single-edge nibble transmission) and CAN data transfer with very low latency and jitter.}, language = {en} } @misc{BraunKrafftTippkoetter2022, author = {Braun, Lena and Krafft, Simone and Tippk{\"o}tter, Nils}, title = {Combined supercritical carbon dioxide extraction and chromatography of the algae fatty linoleic and linolenic acid}, series = {Chemie Ingenieur Technik}, volume = {94}, journal = {Chemie Ingenieur Technik}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.202255308}, pages = {1304}, year = {2022}, abstract = {A method for the integrated extraction and separation of fatty acids from algae using supercritical CO2 is presented. Desmodesmus obliquus and Chlorella sorokiniana were used as algae. First, a method for chromatographic separation of fatty acids of different degrees of saturation was established and optimized. Then, an integrated method for supercritical extraction was developed for both algal species. It was also verified whether prior cell disruption was beneficial for extraction. In developing the method for chromatographic separation, statistical experimental design was used to determine the optimal parameter settings. The methanol content in the mobile phase proved to be the most important parameter for successful separation of the three unsaturated fatty acids oleic acid, linoleic acid, and linolenic acid. Supercritical extraction with dried algae showed that about four times more fatty acids can be extracted from C. sorokiniana relative to the dry mass used.}, language = {en} }