@article{HuckPoghossianKerroumietal.2014,
  author    = {Huck, Christina and Poghossian, Arshak and Kerroumi, Iman and Schusser, Sebastian and B{\"a}cker, Matthias and Zander, Willi and Schubert, J{\"u}rgen and Buniatyan, Vahe V. and Martirosyan, Norayr W. and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Multiparameter sensor chip with Barium Strontium Titanate as multipurpose material},
  series = {Electroanalysis},
  volume    = {26},
  journal   = {Electroanalysis},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-4109 (E-Journal); 1040-0397 (Print)},
  doi       = {10.1002/elan.201400076},
  pages     = {980 -- 987},
  year      = {2014},
  abstract  = {It is well known that biochemical and biotechnological processes are strongly dependent and affected by a variety of physico-chemical parameters such as pH value, temperature, pressure and electrolyte conductivity. Therefore, these quantities have to be monitored or controlled in order to guarantee a stable process operation, optimization and high yield. In this work, a sensor chip for the multiparameter detection of three physico-chemical parameters such as electrolyte conductivity, pH and temperature is realized using barium strontium titanate (BST) as multipurpose material. The chip integrates a capacitively coupled four-electrode electrolyte-conductivity sensor, a capacitive field-effect pH sensor and a thin-film Pt-temperature sensor. Due to the multifunctional properties of BST, it is utilized as final outermost coating layer of the processed sensor chip and serves as passivation and protection layer as well as pH-sensitive transducer material at the same time. The results of testing of the individual sensors of the developed multiparameter sensor chip are presented. In addition, a quasi-simultaneous multiparameter characterization of the sensor chip in buffer solutions with different pH value and electrolyte conductivity is performed. To study the sensor behavior and the suitability of BST as multifunctional material under harsh environmental conditions, the sensor chip was exemplarily tested in a biogas digestate.},
  language  = {en}
}
@article{SawadaNakazawaTakenagaetal.2014,
  author    = {Sawada, Kazuaki and Nakazawa, Hirokazu and Takenaga, Shoko and Hizawa, Takeshi and Futagawa, Masato and Dasai, Fumihiro and Sakurai, Takashi and Okumura, Koichi and Hattori, Toshiaki and Ishida, Makoto},
  title     = {Multimodal bioimage sensor},
  series = {IEICE transactions on fundamentals of electronics, communidations and computer sciences},
  volume    = {E97-A (2014)},
  journal   = {IEICE transactions on fundamentals of electronics, communidations and computer sciences},
  number    = {3},
  publisher = {IEICE},
  address   = {Tokyo},
  issn      = {0916-8508 (Print) ; 1745-1337 (Online)},
  doi       = {10.1587/transfun.E97.A.726},
  pages     = {726 -- 733},
  year      = {2014},
  abstract  = {To visualize the biochemical distribution two-dimensionally, we invented a solid-state-type ion image sensor that indicates the chemical activity of solutions and cells. The device, which consists of a CCD array covered with a functionalized membrane to detect charge accumulation, is highly sensitive to changes in the concentration and two-dimensional distribution of ions and biomaterials.},
  language  = {en}
}
@article{FuestKotliarWalteretal.2014,
  author    = {Fuest, Matthias and Kotliar, Konstantin and Walter, Peter and Plange, Niklas},
  title     = {Monitoring intraocular pressure changes after intravitreal Ranibizumab injection using rebound tonometry},
  series = {Ophthalmic and physiological optics},
  volume    = {34},
  journal   = {Ophthalmic and physiological optics},
  number    = {4},
  publisher = {Wiley-Blackwell},
  address   = {Oxford},
  issn      = {1475-1313 (E-Journal); 0275-5408 (Print)},
  doi       = {10.1111/opo.12134},
  pages     = {438 -- 444},
  year      = {2014},
  language  = {en}
}
@article{TuraliyevaYeshibaevDigeletal.2014,
  author    = {Turaliyeva, M. and Yeshibaev, A. and Digel, Ilya and Elibayeva, G. and Sydykova, A. and Uspabayeva, A. and Dosybayeva, G. and Zhylysbayeva, A. and Lakhanova, K.},
  title     = {Molecular-genetic identification of emerged novel invasive pathogens of Asiatic Elm Ulmus pumila L},
  series = {Life science journal},
  volume    = {11},
  journal   = {Life science journal},
  number    = {Spec. iss. 5s},
  publisher = {Marsland Press},
  address   = {New York},
  issn      = {1097-8135},
  doi       = {10.7537/marslsj1105s14.33},
  pages     = {171 -- 175},
  year      = {2014},
  abstract  = {The dwarf elm Ulmus pumila L. (Ulmaceae) is one of indigenous species of flora in Kazakhstan and forms a basis of dendroflora in virtually all settlements of the region. In the past decade, multiple outbreaks of previously unknown diseases of the small-leaved elm have been registered. In our study, by the molecular-genetic analysis it was found that the pathogens responsible for the outbreaks are microfungi belonging to the genus Fusarium - F. solani and F. oxysporum. The nucleotide sequences (ITS regions) isolated from the diseased trees showed very high similarity with the GenBank control numbers EU625403.1 and FJ478128.1 (100.0 and 99.0 \% respectively). Oncoming research will focus on the search of natural microbial antagonists of the discovered phytopathogens.},
  language  = {en}
}
@article{LeinhosSchusserBaeckeretal.2014,
  author    = {Leinhos, Marcel and Schusser, Sebastian and B{\"a}cker, Matthias and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Micromachined multi-parameter sensor chip for the control of polymer-degradation medium},
  series = {Physica Status Solidi (A) : special issue on engineering and functional interfaces},
  volume    = {211},
  journal   = {Physica Status Solidi (A) : special issue on engineering and functional interfaces},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)},
  doi       = {10.1002/pssa.201330364},
  pages     = {1346 -- 1351},
  year      = {2014},
  abstract  = {It is well known that the degradation environment can strongly influence the biodegradability and kinetics of biodegradation processes of polymers. Therefore, besides the monitoring of the degradation process, it is also necessary to control the medium in which the degradation takes place. In this work, a micromachined multi-parameter sensor chip for the control of the polymer-degradation medium has been developed. The chip combines a capacitive field-effect pH sensor, a four-electrode electrolyte-conductivity sensor and a thin-film Pt-temperature sensor. The results of characterization of individual sensors are presented. In addition, the multi-parameter sensor chip together with an impedimetric polymer-degradation sensor was simultaneously characterized in degradation solutions with different pH and electrolyte conductivity. The obtained results demonstrate the feasibility of the multi-parameter sensor chip for the control of the polymer-degradation medium.},
  language  = {en}
}
@article{MartinGonzalezKotliarRiosMartinezetal.2014,
  author    = {Martin-Gonzalez, Anabel and Kotliar, Konstantin and Rios-Martinez, Jorge and Lanzl, Ines and Navab, Nassir},
  title     = {Mediated-reality magnification for macular degeneration rehabilitation},
  series = {Journal of Modern Optics},
  volume    = {61},
  journal   = {Journal of Modern Optics},
  number    = {17},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1362-3044},
  doi       = {10.1080/09500340.2014.936110},
  pages     = {1400 -- 1408},
  year      = {2014},
  language  = {en}
}
@article{HafnerDemetzWeickertetal.2014,
  author    = {Hafner, David and Demetz, Oliver and Weickert, Joachim and Reißel, Martin},
  title     = {Mathematical Foundations and Generalisations of the Census Transform for Robust Optic Flow Computation},
  series = {Journal of Mathematical Imaging and Vision},
  journal   = {Journal of Mathematical Imaging and Vision},
  publisher = {Springer},
  address   = {New York},
  issn      = {1573-7683 (Online)},
  doi       = {10.1007/s10851-014-0529-9},
  year      = {2014},
  language  = {en}
}
@article{PoghossianSchoening2014,
  author    = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Label-free sensing of biomolecules with field-effect devices for clinical applications},
  series = {Electroanalysis},
  volume    = {26},
  journal   = {Electroanalysis},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-4109 (E-Journal); 1040-0397 (Print)},
  doi       = {10.1002/elan.201400073},
  pages     = {1197 -- 1213},
  year      = {2014},
  abstract  = {Among the variety of transducer concepts proposed for label-free detection of biomolecules, the semiconductor field-effect device (FED) is one of the most attractive platforms. As medical techniques continue to progress towards diagnostic and therapies based on biomarkers, the ability of FEDs for a label-free, fast and real-time detection of multiple pathogenic and physiologically relevant molecules with high specificity and sensitivity offers very promising prospects for their application in point-of-care and personalized medicine for an early diagnosis and treatment of diseases. The presented paper reviews recent advances and current trends in research and development of different FEDs for label-free, direct electrical detection of charged biomolecules by their intrinsic molecular charge. The authors are mainly focusing on the detection of the DNA hybridization event, antibody-antigen affinity reaction as well as clinically relevant biomolecules such as cardiac and cancer biomarkers.},
  language  = {en}
}
@article{WuBronderPoghossianetal.2014,
  author    = {Wu, Chunsheng and Bronder, Thomas and Poghossian, Arshak and Werner, Frederik and B{\"a}cker, Matthias and Sch{\"o}ning, Michael Josef},
  title     = {Label-free electrical detection of DNA with a multi-spot LAPS: First step towards light-addressable DNA chips},
  series = {Physica status solidi A : Applications and materials science},
  volume    = {211},
  journal   = {Physica status solidi A : Applications and materials science},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)},
  doi       = {10.1002/pssa.201330442},
  pages     = {1423 -- 1428},
  year      = {2014},
  abstract  = {A multi-spot (4 × 4 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al-p-Si-SiO2 structure has been applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. Single-stranded probe ssDNA molecules (20 bases) were covalently immobilized onto the silanized SiO2 gate surface. The unspecific adsorption of mismatch ssDNA on the MLAPS gate surface was blocked by bovine serum albumin molecules. To reduce the screening effect and to achieve a high sensor signal, the measurements were performed in a low ionic-strength solution. The photocurrent-voltage (I-V) curves were simultaneously recorded on all 16 spots after each surface functionalization step. Large shifts of I-V curves of 25 mV were registered after the DNA immobilization and hybridization event. In contrast, a small potential shift (∼5 mV) was observed in case of mismatch ssDNA, revealing good specificity of the sensor. The obtained results demonstrate the potential of the MLAPS as promising transducer platform for the multi-spot label-free electrical detection of DNA molecules by their intrinsic molecular charge.},
  language  = {en}
}
@article{BronderWuPoghossianetal.2014,
  author    = {Bronder, Thomas and Wu, Chunsheng and Poghossian, Arshak and Werner, Frederik and Keusgen, M. and Sch{\"o}ning, Michael Josef},
  title     = {Label-free detection of DNA hybridization with light-addressable potentiometric sensors: comparison of various DNA-immobilization strategies},
  series = {Procedia Engineering},
  volume    = {87},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2014.11.647},
  pages     = {755 -- 758},
  year      = {2014},
  abstract  = {Light-addressable potentiometric sensors (LAPS) consisting of a p-Si-SiO2 and p-Si-SiO2-Au structure, respectively, have been tested for a label-free electrical detection of DNA (deoxyribonucleic acid) hybridization. Three different strategies for immobilizing single-stranded probe DNA (ssDNA) molecules on a LAPS surface have been studied and compared: (a) immobilization of thiol-modified ssDNA on the patterned Au surface via gold-thiol bond, (b) covalent immobilization of amino-modified ssDNA onto the SiO2 surface functionalized with 3-aminopropyltriethoxysilane and (c) layer-by-layer adsorption of negatively charged ssDNA on a positively charged weak polyelectrolyte layer of poly(allylamine hydrochloride).},
  language  = {en}
}