@article{BodeSchlakeIberetal.2000,
  author    = {Bode, J{\"u}rgen and Schlake, Thomas and Iber, Michaela and Sch{\"u}beler, Dirk and Seibler, Jost and Snezhkov, Evgeney and Nikolaev, Lev},
  title     = {The transgeneticist's toolbox: novel methods for the targeted modification of eukaryotic genomes},
  series = {Biological Chemistry},
  volume    = {381},
  journal   = {Biological Chemistry},
  number    = {9-10},
  issn      = {1431-6730},
  doi       = {10.1515/BC.2000.103},
  pages     = {801 -- 813},
  year      = {2000},
  language  = {en}
}
@article{BodeBartschBoulikasetal.1998,
  author    = {Bode, J. and Bartsch, J. and Boulikas, T. and Iber, M. and Mielke, C. and Sch{\"u}beler, D. and Seibler, Jost and Benham, C.},
  title     = {Transcription-promoting genomic sites in mammalia: their elucidation and architectural principles},
  series = {Gene therapy \& molecular biology},
  volume    = {1},
  journal   = {Gene therapy \& molecular biology},
  number    = {1},
  issn      = {1529-9120},
  pages     = {1 -- 29},
  year      = {1998},
  language  = {en}
}
@article{BlockMayWetzeletal.2023,
  author    = {Block, Franziska and May, Alexander and Wetzel, Katharina and Adels, Klaudia and Elbers, Gereon and Schulze, Margit and Monakhova, Yulia},
  title     = {What is the best spectroscopic method for simultaneous analysis of organic acids and (poly)saccharides in biological matrices: Example of Aloe vera extracts?},
  series = {Talanta Open},
  volume    = {7},
  journal   = {Talanta Open},
  number    = {Art. No. 100220},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2666-8319},
  doi       = {10.1016/j.talo.2023.100220},
  pages     = {1 -- 9},
  year      = {2023},
  abstract  = {Several species of (poly)saccharides and organic acids can be found often simultaneously in various biological matrices, e.g., fruits, plant materials, and biological fluids. The analysis of such matrices sometimes represents a challenging task. Using Aloe vera (A. vera) plant materials as an example, the performance of several spectro-scopic methods (80 MHz benchtop NMR, NIR, ATR-FTIR and UV-vis) for the simultaneous analysis of quality parameters of this plant material was compared. The determined parameters include (poly)saccharides such as aloverose, fructose and glucose as well as organic acids (malic, lactic, citric, isocitric, acetic, fumaric, benzoic and sorbic acids). 500 MHz NMR and high-performance liquid chromatography (HPLC) were used as the reference methods. UV-vis data can be used only for identification of added preservatives (benzoic and sorbic acids) and drying agent (maltodextrin) and semiquantitative analysis of malic acid. NIR and MIR spectroscopies combined with multivariate regression can deliver more informative overview of A. vera extracts being able to additionally quantify glucose, aloverose, citric, isocitric, malic, lactic acids and fructose. Low-field NMR measurements can be used for the quantification of aloverose, glucose, malic, lactic, acetic, and benzoic acids. The benchtop NMR method was successfully validated in terms of robustness, stability, precision, reproducibility and limit of detection (LOD) and quantification (LOQ), respectively. All spectroscopic techniques are useful for the screening of (poly)saccharides and organic acids in plant extracts and should be applied according to its availability as well as information and confidence required for the specific analytical goal. Benchtop NMR spectroscopy seems to be the most feasible solution for quality control of A. vera products.},
  language  = {en}
}
@article{BiselliZengDinteretal.1997,
  author    = {Biselli, Manfred and Zeng, Steffen and Dinter, Andre and Eisenkr{\"a}tzer, Detlef},
  title     = {Pilot Scale Expression and Purification of Soluble Protein A Tagged \&\#946;1,6N-Acetylglucosaminyltransferase in CHO Cells / Zeng, Steffen ; Dinter, Andre ; Eisenkr{\"a}tzer, Detlef ; Biselli, Manfred ; Wandrey, Christian ; Berger, Eric G.},
  series = {Biochemical and Biophysical Research Communications. 237 (1997), H. 3},
  journal   = {Biochemical and Biophysical Research Communications. 237 (1997), H. 3},
  isbn      = {0006-291X},
  pages     = {653 -- 658},
  year      = {1997},
  language  = {en}
}
@article{BiselliWandrey1988,
  author    = {Biselli, Manfred and Wandrey, Christian},
  title     = {Reaction Mechanism of an Endoglucanase of Trichoderma Reesei QM 9414 using Cellodextrins as Substrate},
  series = {Technology of biological processes, safety in biotechnology, applied genetic engineering : lectures held at the 5th DECHEMA Annual Meeting of Biotechnologists, May 12 - 13, 1987, [Frankfurt, Main] / [hrsg. von Dieter Behrens ...]},
  journal   = {Technology of biological processes, safety in biotechnology, applied genetic engineering : lectures held at the 5th DECHEMA Annual Meeting of Biotechnologists, May 12 - 13, 1987, [Frankfurt, Main] / [hrsg. von Dieter Behrens ...]},
  publisher = {VCH},
  address   = {Weinheim},
  pages     = {425 -- 429},
  year      = {1988},
  language  = {en}
}
@article{BiselliVanderPolSpohnetal.1994,
  author    = {Biselli, Manfred and Van der Pol, Jens J. and Spohn, Uwe and Eberhardt, Rolf},
  title     = {On-line monitoring of an animal cell culture with multi-channel flow injection analysis / van der Pol, Jens J.; Spohn, Uwe ; Eberhardt, Rolf ; G{\"a}tgens, Jochen ; Biselli, Manfred ; Wandrey, Christian ; Tramper, Johannes},
  series = {Journal of Biotechnology. 37 (1994), H. 3},
  journal   = {Journal of Biotechnology. 37 (1994), H. 3},
  isbn      = {0168-1656},
  pages     = {253 -- 264},
  year      = {1994},
  language  = {en}
}
@article{BiselliVanderPolMachniketal.1997,
  author    = {Biselli, Manfred and Van der Pol, Jens J. and Machnik, Marc and Portela-Klein, Theresa},
  title     = {On-line immunoanalysis of monoclonal antibodies during a continuous culture of hybridoma cells / Jens J. van der Pol, Marc Machnik, Manfred Biselli, Theresa Portela-Klein, Cornelis D. de Gooijer, Johannes Tramper und Christian Wandrey},
  series = {Cytotechnology. 24 (1997), H. 1},
  journal   = {Cytotechnology. 24 (1997), H. 1},
  isbn      = {0920-9069},
  pages     = {19 -- 30},
  year      = {1997},
  language  = {en}
}
@article{BiselliVanderPolJokschetal.1995,
  author    = {Biselli, Manfred and Van der Pol, Jens J. and Joksch, Burkhard and Galgens, Jochem},
  title     = {On-line control of an immobilized hybridoma culture with multi-channel flow injektion analysis / Jens J. van der Pol, Burkhard Joksch, Jochem Galgens, Manfred Biselli, Cornelis D. de Gooijer, Johannes Tramper and Christian Wandrey},
  series = {Journal of Biotechnology. 43 (1995), H. 3},
  journal   = {Journal of Biotechnology. 43 (1995), H. 3},
  isbn      = {0168-1656},
  pages     = {229 -- 242},
  year      = {1995},
  language  = {en}
}
@article{BiselliVanderPolJokschetal.1994,
  author    = {Biselli, Manfred and Van der Pol, Jens J. and Joksch, B. and Spohn, U.},
  title     = {On-line monitoring and control of glucose, glutamine, lactate and ammonium during a high-cell-density cultivation of hybridoma cells / van der Pol, Jens J. ; Joksch, B. ; Spohn, U. ; Biselli, M. ; Wandrey, C.},
  series = {Proceedings of the sixth international meeting of the Japanese Association for Animal Cell Technology [JAACT 93]: Nagoya, Japan, November 9 - 12, 1993 / ed. by T. Kobayashi},
  journal   = {Proceedings of the sixth international meeting of the Japanese Association for Animal Cell Technology [JAACT 93]: Nagoya, Japan, November 9 - 12, 1993 / ed. by T. Kobayashi},
  publisher = {Springer Netherland},
  address   = {Berlin},
  isbn      = {0-7923-3156-7},
  pages     = {167 -- 170},
  year      = {1994},
  language  = {en}
}
@article{BiselliVanderPolJokschetal.1992,
  author    = {Biselli, Manfred and Van der Pol, Jens J. and Joksch, B. and Eberhardt, R.},
  title     = {Development of an enzymatic multichannel flow injection analysis system for monitoring mammalian cell fermentations / Van der Pol, J.J.; Joksch, B.; Eberhardt, R.; Biselli, M.; Wandrey, C., Tramper, J.},
  series = {Biosensors : fundamentals, technologies and applications ; contributions to the BMFT status seminar with international participation May, 12 to 14, 1991, Internationales Bildungs-Centrum Bogensee/Brandenburg, Germany / org. by ZIM-Zentralinstitut f{\"u}r Molekularbiologie, Berlin-Buch and GBF, Braunschweig. Ed. by F. Scheller},
  journal   = {Biosensors : fundamentals, technologies and applications ; contributions to the BMFT status seminar with international participation May, 12 to 14, 1991, Internationales Bildungs-Centrum Bogensee/Brandenburg, Germany / org. by ZIM-Zentralinstitut f{\"u}r Molekularbiologie, Berlin-Buch and GBF, Braunschweig. Ed. by F. Scheller},
  publisher = {VCH},
  address   = {Weinheim},
  isbn      = {3527284370},
  pages     = {349 -- 352},
  year      = {1992},
  language  = {en}
}