@article{SiqueiraMolinnusBegingetal.2014,
  author    = {Siqueira, Jose R. and Molinnus, Denise and Beging, Stefan and Sch{\"o}ning, Michael Josef},
  title     = {Incorporating a hybrid urease-carbon nanotubes sensitive nanofilm on capacitive field-effect sensors for urea detection},
  series = {Analytical chemistry},
  volume    = {86},
  journal   = {Analytical chemistry},
  number    = {11},
  publisher = {ACS Publications},
  address   = {Columbus},
  issn      = {1520-6882 (E-Journal); 0003-2700 (Print); 0096-4484 (Print)},
  doi       = {10.1021/ac500458s},
  pages     = {5370 -- 5375},
  year      = {2014},
  abstract  = {The ideal combination among biomolecules and nanomaterials is the key for reaching biosensing units with high sensitivity. The challenge, however, is to find out a stable and sensitive film architecture that can be incorporated on the sensor's surface. In this paper, we report on the benefits of incorporating a layer-by-layer (LbL) nanofilm of polyamidoamine (PAMAM) dendrimer and carbon nanotubes (CNTs) on capacitive electrolyte-insulator-semiconductor (EIS) field-effect sensors for detecting urea. Three sensor arrangements were studied in order to investigate the adequate film architecture, involving the LbL film with the enzyme urease: (i) urease immobilized directly onto a bare EIS [EIS-urease] sensor; (ii) urease atop the LbL film over the EIS [EIS-(PAMAM/CNT)-urease] sensor; and (iii) urease sandwiched between the LbL film and another CNT layer [EIS-(PAMAM/CNT)-urease-CNT]. The surface morphology of all three urea-based EIS biosensors was investigated by atomic force microscopy (AFM), while the biosensing abilities were studied by means of capacitance-voltage (C/V) and dynamic constant-capacitance (ConCap) measureaments at urea concentrations ranging from 0.1 mM to 100 mM. The EIS-urease and EIS-(PAMAM/CNT)-urease sensors showed similar sensitivity (∼18 mV/decade) and a nonregular signal behavior as the urea concentration increased. On the other hand, the EIS-(PAMAM/CNT)-urease-CNT sensor exhibited a superior output signal performance and higher sensitivity of about 33 mV/decade. The presence of the additional CNT layer was decisive to achieve a urea based EIS sensor with enhanced properties. Such sensitive architecture demonstrates that the incorporation of an adequate hybrid enzyme-nanofilm as sensing unit opens new prospects for biosensing applications using the field-effect sensor platform.},
  language  = {en}
}
@article{SimonisRugeMuellerVeggianetal.2003,
  author    = {Simonis, A. and Ruge, C. and M{\"u}ller-Veggian, Mattea and L{\"u}th, H. and Sch{\"o}ning, Michael Josef},
  title     = {A long-term stable macroporoustype EIS structure for electrochemical sensor applications},
  series = {Sensors and Actuators B. 91 (2003), H. 1-3},
  journal   = {Sensors and Actuators B. 91 (2003), H. 1-3},
  isbn      = {0925-4005},
  pages     = {21 -- 25},
  year      = {2003},
  language  = {en}
}
@article{SimonisLuethWangetal.2004,
  author    = {Simonis, A. and L{\"u}th, H. and Wang, J. and Sch{\"o}ning, Michael Josef},
  title     = {New concepts of miniaturised reference electrodes in silicon technology for potentiometric sensor systems},
  series = {Sensors and Actuators B. 103 (2004), H. 1-2},
  journal   = {Sensors and Actuators B. 103 (2004), H. 1-2},
  isbn      = {0925-4005},
  pages     = {429 -- 435},
  year      = {2004},
  language  = {en}
}
@article{SimonisLuethWangetal.2003,
  author    = {Simonis, A. and L{\"u}th, H. and Wang, J. and Sch{\"o}ning, Michael Josef},
  title     = {Strategies of miniaturised reference electrodes integrated in a silicon-based „one chip" pH sensor},
  series = {Sensors. 3 (2003), H. 9},
  journal   = {Sensors. 3 (2003), H. 9},
  isbn      = {1424-8220},
  pages     = {330 -- 339},
  year      = {2003},
  language  = {en}
}
@article{SimonisKringsLuethetal.2001,
  author    = {Simonis, A. and Krings, T. and L{\"u}th, H. and Wang, J. and Sch{\"o}ning, Michael Josef},
  title     = {A „hybrid" thin-film pH sensor with integrated thick-film reference},
  series = {Sensors. 1 (2001), H. 6},
  journal   = {Sensors. 1 (2001), H. 6},
  isbn      = {1424-8220},
  pages     = {183 -- 192},
  year      = {2001},
  language  = {en}
}
@article{SimonisDawgulLuethetal.2005,
  author    = {Simonis, A. and Dawgul, M. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef},
  title     = {Miniaturised reference electrodes for field-effect sensors compatible to silicon chip technology},
  series = {Electrochimica Acta. 51 (2005), H. 5},
  journal   = {Electrochimica Acta. 51 (2005), H. 5},
  isbn      = {0013-4686},
  doi       = {10.1016/j.electacta.2005.04.063},
  pages     = {930 -- 937},
  year      = {2005},
  language  = {en}
}
@article{SiegertMcLeishBaumannetal.2005,
  author    = {Siegert, Petra and McLeish, Michael J. and Baumann, Martin and Iding, Hans and Kneen, Malea M. and Kenyon, George L. and Pohl, Martina},
  title     = {Exchanging the substrate specificities of pyruvate decarboxylase from Zymomonas mobilis and benzoylformate decarboxylase from Pseudomonas putida},
  series = {Protein engineering, design, and selection : peds},
  volume    = {Vol. 18},
  journal   = {Protein engineering, design, and selection : peds},
  number    = {Iss. 7},
  issn      = {1460-213X (E-Journal); 1741-0134 (E-Journal); 0269-2139 (Print); 1741-0126 (Print)},
  pages     = {345 -- 357},
  year      = {2005},
  language  = {en}
}
@article{SchuetzWeissbeckerSchrothetal.2001,
  author    = {Sch{\"u}tz, S. and Weißbecker, G. and Schroth, P. and Sch{\"o}ning, Michael Josef},
  title     = {Linkage of inanimate structures to biological systems - smart materials in biological micro- nanosystems},
  series = {Smart materials : proceedings of the 1st Caesarium, Bonn, November 17 - 19, 1999 / Karl-Heinz Hoffmann ed.},
  journal   = {Smart materials : proceedings of the 1st Caesarium, Bonn, November 17 - 19, 1999 / Karl-Heinz Hoffmann ed.},
  publisher = {Springer},
  address   = {Berlin [u.a.]},
  isbn      = {3-540-67957-X},
  pages     = {149 -- 157},
  year      = {2001},
  language  = {en}
}
@article{SchuetzSchoeningSchrothetal.2000,
  author    = {Sch{\"u}tz, S. and Sch{\"o}ning, Michael Josef and Schroth, P. and Weißbecker, B. and Kordos, P. and L{\"u}th, H. and Hummel, Hans E.},
  title     = {An insectbased BioFET as a bioelectronic nose},
  series = {Sensors and Actuators B. 65 (2000), H. 1-3},
  journal   = {Sensors and Actuators B. 65 (2000), H. 1-3},
  isbn      = {0925-4005},
  pages     = {291 -- 295},
  year      = {2000},
  language  = {en}
}
@article{SchoeningWangKrauseetal.2002,
  author    = {Sch{\"o}ning, Michael Josef and Wang, Josepf and Krause, Robin and Block, Kirstin and Musameh, Mustafa and Mulchandani, Ashok and Mulchandani, Priti and Chen, Wilfred},
  title     = {Dual amperometric-potentiometric biosensor detection system for monitoring organophosphorus neurotoxins},
  series = {Analyica Chimica Acta. 469 (2002), H. 2},
  journal   = {Analyica Chimica Acta. 469 (2002), H. 2},
  isbn      = {0378-4304},
  pages     = {197 -- 203},
  year      = {2002},
  language  = {en}
}