@article{MiyamotoWagnerSchoeningetal.2011,
  author    = {Miyamoto, K. and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, T.},
  title     = {Multi-well structure for cell culture on the chemical imaging sensor},
  publisher = {IEEE},
  address   = {New York},
  pages     = {2130 -- 2132},
  year      = {2011},
  language  = {en}
}
@article{SchubertSchoeningMourzinaetal.2001,
  author    = {Schubert, J. and Sch{\"o}ning, Michael Josef and Mourzina, Y. G. and Legin, A. V. and Vlasov, Y. G. and Zander, W. and L{\"u}th, H.},
  title     = {Multicomponent thin films for electrochemical sensor applications prepared by pulsed laser deposition},
  series = {Sensors and Actuators B. 76 (2001), H. 1-3},
  journal   = {Sensors and Actuators B. 76 (2001), H. 1-3},
  isbn      = {0925-4005},
  pages     = {327 -- 330},
  year      = {2001},
  language  = {en}
}
@article{HuckPoghossianKerroumietal.2014,
  author    = {Huck, Christina and Poghossian, Arshak and Kerroumi, Iman and Schusser, Sebastian and B{\"a}cker, Matthias and Zander, Willi and Schubert, J{\"u}rgen and Buniatyan, Vahe V. and Martirosyan, Norayr W. and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Multiparameter sensor chip with Barium Strontium Titanate as multipurpose material},
  series = {Electroanalysis},
  volume    = {26},
  journal   = {Electroanalysis},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-4109 (E-Journal); 1040-0397 (Print)},
  doi       = {10.1002/elan.201400076},
  pages     = {980 -- 987},
  year      = {2014},
  abstract  = {It is well known that biochemical and biotechnological processes are strongly dependent and affected by a variety of physico-chemical parameters such as pH value, temperature, pressure and electrolyte conductivity. Therefore, these quantities have to be monitored or controlled in order to guarantee a stable process operation, optimization and high yield. In this work, a sensor chip for the multiparameter detection of three physico-chemical parameters such as electrolyte conductivity, pH and temperature is realized using barium strontium titanate (BST) as multipurpose material. The chip integrates a capacitively coupled four-electrode electrolyte-conductivity sensor, a capacitive field-effect pH sensor and a thin-film Pt-temperature sensor. Due to the multifunctional properties of BST, it is utilized as final outermost coating layer of the processed sensor chip and serves as passivation and protection layer as well as pH-sensitive transducer material at the same time. The results of testing of the individual sensors of the developed multiparameter sensor chip are presented. In addition, a quasi-simultaneous multiparameter characterization of the sensor chip in buffer solutions with different pH value and electrolyte conductivity is performed. To study the sensor behavior and the suitability of BST as multifunctional material under harsh environmental conditions, the sensor chip was exemplarily tested in a biogas digestate.},
  language  = {en}
}
@article{ReisertGeisslerWeileretal.2015,
  author    = {Reisert, Steffen and Geissler, H. and Weiler, C. and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {Multiple sensor-type system for monitoring the microbicidal effectiveness of aseptic sterilisation processes},
  series = {Food control},
  volume    = {47},
  journal   = {Food control},
  issn      = {1873-7129 (E-Journal); 0956-7135 (Print)},
  doi       = {10.1016/j.foodcont.2014.07.063},
  pages     = {615 -- 622},
  year      = {2015},
  abstract  = {The present work describes a novel multiple sensor-type system for the real-time analysis of aseptic sterilisation processes employing gaseous hydrogen peroxide (H2O2) as a sterilant. The inactivation kinetics of Bacillus atrophaeus by gaseous H2O2 have been investigated by means of a methodical calibration experiment, taking into account the process variables H2O2 concentration, humidity and gas temperature. It has been found that the microbicidal effectiveness at H2O2 concentrations above 2\% v/v is largely determined by the concentration itself, while at lower H2O2 concentrations, the gas temperature and humidity play a leading role. Furthermore, the responses of different types of gas sensors towards the influencing factors of the sterilisation process have been analysed within the same experiment. Based on a correlation established between the inactivation kinetics and the sensor responses, a calorimetric H2O2 sensor and a metal-oxide semiconductor (MOX) sensor have been identified as possible candidates for monitoring the microbicidal effectiveness of aseptic sterilisation processes employing gaseous H2O2. Therefore, two linear models that describe the relationship between sensor response and microbicidal effectiveness have been proposed.},
  language  = {en}
}
@article{AchtsnichtPourshahidiOffenhaeusseretal.2019,
  author    = {Achtsnicht, Stefan and Pourshahidi, Ali Mohammad and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim},
  title     = {Multiplex detection of different magnetic beads using frequency scanning in magnetic frequency mixing technique},
  series = {Sensors},
  volume    = {19},
  journal   = {Sensors},
  number    = {11},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s19112599},
  pages     = {13 Seiten},
  year      = {2019},
  abstract  = {In modern bioanalytical methods, it is often desired to detect several targets in one sample within one measurement. Immunological methods including those that use superparamagnetic beads are an important group of techniques for these applications. The goal of this work is to investigate the feasibility of simultaneously detecting different superparamagnetic beads acting as markers using the magnetic frequency mixing technique. The frequency of the magnetic excitation field is scanned while the lower driving frequency is kept constant. Due to the particles' nonlinear magnetization, mixing frequencies are generated. To record their amplitude and phase information, a direct digitization of the pickup-coil's signal with subsequent Fast Fourier Transformation is performed. By synchronizing both magnetic beads using frequency scanning in magnetic frequency mixing technique magnetic fields, a stable phase information is gained. In this research, it is shown that the amplitude of the dominant mixing component is proportional to the amount of superparamagnetic beads inside a sample. Additionally, it is shown that the phase does not show this behaviour. Excitation frequency scans of different bead types were performed, showing different phases, without correlation to their diverse amplitudes. Two commercially available beads were selected and a determination of their amount in a mixture is performed as a demonstration for multiplex measurements.},
  language  = {en}
}
@article{PourshahidiAchtsnichtNambipareecheeetal.2021,
  author    = {Pourshahidi, Ali Mohammad and Achtsnicht, Stefan and Nambipareechee, Mrinal Murali and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim},
  title     = {Multiplex detection of magnetic beads using offset field dependent frequency mixing magnetic detection},
  series = {Sensors},
  volume    = {21},
  journal   = {Sensors},
  number    = {17},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s21175859},
  pages     = {16 Seiten},
  year      = {2021},
  abstract  = {Magnetic immunoassays employing Frequency Mixing Magnetic Detection (FMMD) have recently become increasingly popular for quantitative detection of various analytes. Simultaneous analysis of a sample for two or more targets is desirable in order to reduce the sample amount, save consumables, and save time. We show that different types of magnetic beads can be distinguished according to their frequency mixing response to a two-frequency magnetic excitation at different static magnetic offset fields. We recorded the offset field dependent FMMD response of two different particle types at frequencies ƒ₁ + n⋅ƒ₂, n = 1, 2, 3, 4 with ƒ₁ = 30.8 kHz and ƒ₂ = 63 Hz. Their signals were clearly distinguishable by the locations of the extremes and zeros of their responses. Binary mixtures of the two particle types were prepared with different mixing ratios. The mixture samples were analyzed by determining the best linear combination of the two pure constituents that best resembled the measured signals of the mixtures. Using a quadratic programming algorithm, the mixing ratios could be determined with an accuracy of greater than 14\%. If each particle type is functionalized with a different antibody, multiplex detection of two different analytes becomes feasible.},
  language  = {en}
}
@article{KarschuckSchmidtAchtsnichtetal.2023,
  author    = {Karschuck, Tobias and Schmidt, Stefan and Achtsnicht, Stefan and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Multiplexing system for automated characterization of a capacitive field-effect sensor array},
  series = {Physica Status Solidi A},
  volume    = {220},
  journal   = {Physica Status Solidi A},
  number    = {22},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6300 (Print)},
  doi       = {10.1002/pssa.202300265},
  pages     = {7 Seiten},
  year      = {2023},
  abstract  = {In comparison to single-analyte devices, multiplexed systems for a multianalyte detection offer a reduced assay time and sample volume, low cost, and high throughput. Herein, a multiplexing platform for an automated quasi-simultaneous characterization of multiple (up to 16) capacitive field-effect sensors by the capacitive-voltage (C-V) and the constant-capacitance (ConCap) mode is presented. The sensors are mounted in a newly designed multicell arrangement with one common reference electrode and are electrically connected to the impedance analyzer via the base station. A Python script for the automated characterization of the sensors executes the user-defined measurement protocol. The developed multiplexing system is tested for pH measurements and the label-free detection of ligand-stabilized, charged gold nanoparticles.},
  language  = {en}
}
@article{KhaydukovaZadorozhnayaKirsanovetal.2014,
  author    = {Khaydukova, M. M. and Zadorozhnaya, O. A. and Kirsanov, D. O. and Iken, Heiko and Rolka, David and Sch{\"o}ning, Michael Josef and Babain, V. A. and Vlasov, Yu. G. and Legin, A. V.},
  title     = {Multivariate processing of atomic-force microscopy images for detection of the response of plasticized polymeric membranes},
  series = {Russian journal of applied chemistry},
  volume    = {87},
  journal   = {Russian journal of applied chemistry},
  number    = {3},
  publisher = {Springer},
  address   = {Dordrecht},
  issn      = {1608-3296 (E-Journal); 1070-4272 (Print)},
  doi       = {10.1134/S1070427214030112},
  pages     = {307 -- 314},
  year      = {2014},
  abstract  = {The possibility of using the atomic-force microscopy as a method for detection of the analytical signal from plasticized polymeric sensor membranes was analyzed. The surfaces of cadmium-selective membranes based on two polymeric matrices were examined. The digital images were processed with multivariate image analysis techniques. A correlation was found between the surface profile of an ion-selective membrane and the concentration of the ion in solution.},
  language  = {en}
}
@article{PoghossianAbouzarChristiaensetal.2007,
  author    = {Poghossian, Arshak and Abouzar, Maryam H. and Christiaens, P. and Williams, O. A. and Haenen, K. and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {Nanocrystalline diamond-based field-effect (bio-)chemical sensor},
  series = {8. Dresdner Sensor-Symposium : Sensoren f{\"u}r Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme f{\"u}r die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung f{\"u}r die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.)},
  journal   = {8. Dresdner Sensor-Symposium : Sensoren f{\"u}r Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme f{\"u}r die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung f{\"u}r die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.)},
  publisher = {TUDpress, Verl. der Wissenschaften},
  address   = {Dresden},
  isbn      = {978-3-940046-45-1},
  pages     = {191 -- 194},
  year      = {2007},
  language  = {en}
}
@article{ChristiaensAbouzarPoghossianetal.2007,
  author    = {Christiaens, P. and Abouzar, Maryam H. and Poghossian, Arshak and Wagner, Torsten and Bijnens, N. and Williams, O. A. and Daenen, M. and Haenen, K. and Sch{\"o}ning, Michael Josef and Wagner, P.},
  title     = {Nanocrystalline diamond-based field-effect capacitive pH sensor},
  series = {Transducers '07 Eurosensors XXI : digest of technical papers ; the14th International Conference on Solid-State Sensors, Actuators and Microsystems, June 10-14, 2007, Lyon, France / Gilles Delapierre (Ed.)},
  journal   = {Transducers '07 Eurosensors XXI : digest of technical papers ; the14th International Conference on Solid-State Sensors, Actuators and Microsystems, June 10-14, 2007, Lyon, France / Gilles Delapierre (Ed.)},
  publisher = {IEEE},
  address   = {Piscataway},
  isbn      = {1-4244-0841-5},
  pages     = {1891 -- 1894},
  year      = {2007},
  language  = {en}
}