@article{MuribYeapMartensetal.2014,
  author    = {Murib, Mohammed Sharif and Yeap, Weng-Siang and Martens, Daan and Bienstman, Peter and Ceuninck, Ward de and Grinsven, Bart van and Sch{\"o}ning, Michael Josef and Michiels, Luc and Haenen, Ken and Ameloot, Marcel and Serpeng{\"u}zel, Ali and Wagner, Patrick},
  title     = {Photonic detection and characterization of DNA using sapphire microspheres},
  series = {Journal of biomedical optics},
  volume    = {19},
  journal   = {Journal of biomedical optics},
  number    = {9},
  publisher = {SPIE},
  address   = {Bellingham},
  issn      = {1560-2281 (E-Journal); 1083-3668 (Print)},
  doi       = {10.1117/1.JBO.19.9.097006},
  pages     = {097006},
  year      = {2014},
  abstract  = {A microcavity-based deoxyribonucleic acid (DNA) optical biosensor is demonstrated for the first time using synthetic sapphire for the optical cavity. Transmitted and elastic scattering intensity at 1510 nm are analyzed from a sapphire microsphere (radius 500  μm, refractive index 1.77) on an optical fiber half coupler. The 0.43 nm angular mode spacing of the resonances correlates well with the optical size of the sapphire sphere. Probe DNA consisting of a 36-mer fragment was covalently immobilized on a sapphire microsphere and hybridized with a 29-mer target DNA. Whispering gallery modes (WGMs) were monitored before the sapphire was functionalized with DNA and after it was functionalized with single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). The shift in WGMs from the surface modification with DNA was measured and correlated well with the estimated thickness of the add-on DNA layer. It is shown that ssDNA is more uniformly oriented on the sapphire surface than dsDNA. In addition, it is shown that functionalization of the sapphire spherical surface with DNA does not affect the quality factor (Q≈104) of the sapphire microspheres. The use of sapphire is especially interesting because this material is chemically resilient, biocompatible, and widely used for medical implants.},
  language  = {en}
}
@article{MarxSchenkBehrensetal.2013,
  author    = {Marx, Ulrich and Schenk, Friedrich and Behrens, Jan and Meyr, Ulrike and Wanek, Paul and Zang, Werner and Schmitt, Robert and Br{\"u}stle, Oliver and Zenke, Martin and Klocke, Fritz},
  title     = {Automatic production of induced pluripotent stem cells},
  series = {Procedia CIRP : First CIRP Conference on BioManufacturing},
  volume    = {Vol. 5},
  journal   = {Procedia CIRP : First CIRP Conference on BioManufacturing},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2212-8271},
  pages     = {2 -- 6},
  year      = {2013},
  language  = {en}
}
@inproceedings{PfaffVinsonneauBurnham2006,
  author    = {Pfaff, Raphael and Vinsonneau, B. and Burnham, K. J.},
  title     = {Multiple models for nonlinear systems},
  series = {Proceedings / Eigteenth International Conference on Systems Engineering : ICSE 2006 : 5 - 7 September 2006 ; [held at Coventry University, UK]},
  booktitle = {Proceedings / Eigteenth International Conference on Systems Engineering : ICSE 2006 : 5 - 7 September 2006 ; [held at Coventry University, UK]},
  organization    = {International Conference on Systems Engineering <18, 2006, Coventry>},
  isbn      = {1-84600-013-0},
  pages     = {347 -- 352},
  year      = {2006},
  language  = {en}
}
@inproceedings{PieperSchulz2014,
  author    = {Pieper, Martin and Schulz, Silvia},
  title     = {Teaching Simulation Methods with COMSOL Multiphysics},
  organization    = {COMSOL Conference <2014, Cambridge>},
  pages     = {7},
  year      = {2014},
  abstract  = {This paper describes two courses on simulation methods for graduate students: "Simulation Methods" and "Simulation and Optimization in Virtual Engineering" The courses were planned to teach young engineers how to work with simulation software as well as to understand the necessary mathematical background. As simulation software COMSOL is used. The main philosophy was to combine theory and praxis in a way that motivates the students. In addition "soft skills" should be improved. This was achieved by project work as final examination. As underlying didactical principle the ideas of Bloom's revised taxonomy were followed. The paper basically focusses on educational aspects, e.g. how to structure the course, plan the exercises, organize the project work and include practical COMSOL examples.},
  language  = {en}
}
@incollection{Pietsch2013,
  author    = {Pietsch, Wolfram},
  title     = {A framework for strategic positioning of IT-products},
  series = {Software business : from physical products to software services and solutions : 4th International Conference on Software Business, ICSOB 2013; Potsdam; Germany; 11 June 2013 through 14 June 2013. (Lecture notes in business information processing ; 150)},
  booktitle = {Software business : from physical products to software services and solutions : 4th International Conference on Software Business, ICSOB 2013; Potsdam; Germany; 11 June 2013 through 14 June 2013. (Lecture notes in business information processing ; 150)},
  publisher = {Springer},
  address   = {Berlin},
  doi       = {10.1007/978-3-642-39336-5_11},
  pages     = {102 -- 116},
  year      = {2013},
  abstract  = {IT Products are viewed and managed differently depending on the perspectives and the stage within the life cycle. A model is presented that integrates different perspectives and stages serving as an aid for the analysis of business models and focused positioning of IT-products. Four generic business models are analysed with regard to the product management function in general and the positioning field for IT-products specifically: off-the-shelf (license), license plus service, project, and system service (incl. cloud computing).},
  language  = {en}
}
@article{GuoMiyamotoWagneretal.2014,
  author    = {Guo, Yuanyuan and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Device simulation of the light-addressable potentiometric sensor for the investigation of the spatial resolution},
  series = {Sensors and actuators B: Chemical},
  volume    = {204},
  journal   = {Sensors and actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-3077 (E-Journal); 0925-4005 (Print)},
  doi       = {10.1016/j.snb.2014.08.016},
  pages     = {659 -- 665},
  year      = {2014},
  abstract  = {As a semiconductor-based electrochemical sensor, the light-addressable potentiometric sensor (LAPS) can realize two dimensional visualization of (bio-)chemical reactions at the sensor surface addressed by localized illumination. Thanks to this imaging capability, various applications in biochemical and biomedical fields are expected, for which the spatial resolution is critically significant. In this study, therefore, the spatial resolution of the LAPS was investigated in detail based on the device simulation. By calculating the spatiotemporal change of the distributions of electrons and holes inside the semiconductor layer in response to a modulated illumination, the photocurrent response as well as the spatial resolution was obtained as a function of various parameters such as the thickness of the Si substrate, the doping concentration, the wavelength and the intensity of illumination. The simulation results verified that both thinning the semiconductor substrate and increasing the doping concentration could improve the spatial resolution, which were in good agreement with known experimental results and theoretical analysis. More importantly, new findings of interests were also obtained. As for the dependence on the wavelength of illumination, it was found that the known dependence was not always the case. When the Si substrate was thick, a longer wavelength resulted in a higher spatial resolution which was known by experiments. When the Si substrate was thin, however, a longer wavelength of light resulted in a lower spatial resolution. This finding was explained as an effect of raised concentration of carriers, which reduced the thickness of the space charge region. The device simulation was found to be helpful to understand the relationship between the spatial resolution and device parameters, to understand the physics behind it, and to optimize the device structure and measurement conditions for realizing higher performance of chemical imaging systems.},
  language  = {en}
}
@article{ReisertGeisslerWeileretal.2015,
  author    = {Reisert, Steffen and Geissler, H. and Weiler, C. and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {Multiple sensor-type system for monitoring the microbicidal effectiveness of aseptic sterilisation processes},
  series = {Food control},
  volume    = {47},
  journal   = {Food control},
  issn      = {1873-7129 (E-Journal); 0956-7135 (Print)},
  doi       = {10.1016/j.foodcont.2014.07.063},
  pages     = {615 -- 622},
  year      = {2015},
  abstract  = {The present work describes a novel multiple sensor-type system for the real-time analysis of aseptic sterilisation processes employing gaseous hydrogen peroxide (H2O2) as a sterilant. The inactivation kinetics of Bacillus atrophaeus by gaseous H2O2 have been investigated by means of a methodical calibration experiment, taking into account the process variables H2O2 concentration, humidity and gas temperature. It has been found that the microbicidal effectiveness at H2O2 concentrations above 2\% v/v is largely determined by the concentration itself, while at lower H2O2 concentrations, the gas temperature and humidity play a leading role. Furthermore, the responses of different types of gas sensors towards the influencing factors of the sterilisation process have been analysed within the same experiment. Based on a correlation established between the inactivation kinetics and the sensor responses, a calorimetric H2O2 sensor and a metal-oxide semiconductor (MOX) sensor have been identified as possible candidates for monitoring the microbicidal effectiveness of aseptic sterilisation processes employing gaseous H2O2. Therefore, two linear models that describe the relationship between sensor response and microbicidal effectiveness have been proposed.},
  language  = {en}
}
@article{KhaydukovaZadorozhnayaKirsanovetal.2014,
  author    = {Khaydukova, M. M. and Zadorozhnaya, O. A. and Kirsanov, D. O. and Iken, Heiko and Rolka, David and Sch{\"o}ning, Michael Josef and Babain, V. A. and Vlasov, Yu. G. and Legin, A. V.},
  title     = {Multivariate processing of atomic-force microscopy images for detection of the response of plasticized polymeric membranes},
  series = {Russian journal of applied chemistry},
  volume    = {87},
  journal   = {Russian journal of applied chemistry},
  number    = {3},
  publisher = {Springer},
  address   = {Dordrecht},
  issn      = {1608-3296 (E-Journal); 1070-4272 (Print)},
  doi       = {10.1134/S1070427214030112},
  pages     = {307 -- 314},
  year      = {2014},
  abstract  = {The possibility of using the atomic-force microscopy as a method for detection of the analytical signal from plasticized polymeric sensor membranes was analyzed. The surfaces of cadmium-selective membranes based on two polymeric matrices were examined. The digital images were processed with multivariate image analysis techniques. A correlation was found between the surface profile of an ion-selective membrane and the concentration of the ion in solution.},
  language  = {en}
}
@inproceedings{SchirraWatmuffBauschat2014,
  author    = {Schirra, Julian and Watmuff, Jon and Bauschat, J.-Michael},
  title     = {A relative assessment of existing potential-methodologies to accurately estimate the induced drag of highly non-planar lifting systems},
  series = {Advanced aero concepts, design and operations : Applied Aerodynamics Conference : July 22 -24, 2014, Bristol, UK},
  booktitle = {Advanced aero concepts, design and operations : Applied Aerodynamics Conference : July 22 -24, 2014, Bristol, UK},
  organization    = {Applied Aerodynamics Conference <2014, Bristol>},
  pages     = {1 -- 13},
  year      = {2014},
  language  = {en}
}
@inproceedings{WetterKern2014,
  author    = {Wetter, Martin and Kern, Alexander},
  title     = {Number of lightning strikes to tall structures - comparison of calculations and measurements using a modern lightning monitoring system},
  series = {2014 International Conference on Lightning Protection (ICLP), Shanghai, China},
  booktitle = {2014 International Conference on Lightning Protection (ICLP), Shanghai, China},
  organization    = {International Conference on Lightning Protection <2014, Shanghai>},
  pages     = {1 -- 7},
  year      = {2014},
  language  = {en}
}