@article{Stulpe2014,
  author    = {Stulpe, Werner},
  title     = {From the attempt of certain classical reformulations of quantum mechanics to quasi-probability representations},
  series = {Journal of Mathematical Physics},
  volume    = {55},
  journal   = {Journal of Mathematical Physics},
  number    = {1},
  publisher = {AIP Publishing},
  address   = {College Park, Md.},
  issn      = {222-488},
  doi       = {10.1063/1.4861939},
  pages     = {Artikel 012109},
  year      = {2014},
  abstract  = {The concept of an injective affine embedding of the quantum states into a set of classical states, i.e., into the set of the probability measures on some measurable space, as well as its relation to statistically complete observables is revisited, and its limitation in view of a classical reformulation of the statistical scheme of quantum mechanics is discussed. In particular, on the basis of a theorem concerning a non-denseness property of a set of coexistent effects, it is shown that an injective classical embedding of the quantum states cannot be supplemented by an at least approximate classical description of the quantum mechanical effects. As an alternative approach, the concept of quasi-probability representations of quantum mechanics is considered.},
  language  = {en}
}
@article{PasteurTippkoetterKampeisetal.2014,
  author    = {Pasteur, Aline and Tippk{\"o}tter, Nils and Kampeis, Percy and Ulber, Roland},
  title     = {Optimization of high gradient magnetic separation filter units for the purification of fermentation products},
  series = {IEEE TRANSACTIONS ON MAGNETICS},
  volume    = {50},
  journal   = {IEEE TRANSACTIONS ON MAGNETICS},
  number    = {10},
  publisher = {IEEE},
  address   = {New York, NY},
  issn      = {0018-9464},
  doi       = {10.1109/TMAG.2014.2325535},
  pages     = {Artikel 5000607},
  year      = {2014},
  abstract  = {High gradient magnetic separation (HGMS) has been established since the early 1970s. A more recent application of these systems is the use in bioprocesses. To integrate the HGMS in a fermentation process, it is necessary to optimize the separation matrix with regard to the magnetic separation characteristics and permeability of the non-magnetizable components of the fermentation broth. As part of the work presented here, a combined fluidic and magnetic force finite element model simulation was created using the software COMSOL Multiphysics and compared with separation experiments. Finally, as optimal lattice orientation of the separation matrix, a transversal rhombohedral arrangement was defined. The high suitability of the new filter matrix has been verified by separation experiments.},
  language  = {en}
}
@article{LuisierLempiaeinenScherbichleretal.2014,
  author    = {Luisier, Rapha{\"e}lle and Lempi{\"a}inen, Harri and Scherbichler, Nina and Braeuning, Albert and Geissler, Miriam and Dubost, Valerie and M{\"u}ller, Arne and Scheer, Nico and Chibout, Salah-Dine and Hara, Hisanori and Picard, Frank and Theil, Diethilde and Couttet, Philippe and Vitobello, Antonio and Grenet, Olivier and Grasl-Kraupp, Bettina and Ellinger-Ziegelbauer, Heidrung and Thomson, John P. and Meehan, Richard R. and Elcombe, Clifford R. and Henderson, Colin J. and Wolf, C. Roland and Schwarz, Michael and Moulin, Pierre and Terranova, Remi and Moggs, Jonathan G.},
  title     = {Phenobarbital Induces Cell Cycle Transcriptional Responses in Mouse Liver Humanized for Constitutive Androstane and Pregnane X Receptors},
  series = {Toxicological Sciences},
  volume    = {139},
  journal   = {Toxicological Sciences},
  number    = {2},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {1094-2025},
  doi       = {https://doi.org/10.1093/toxsci/kfu038},
  pages     = {501 -- 511},
  year      = {2014},
  abstract  = {The constitutive androstane receptor (CAR) and the pregnane X receptor (PXR) are closely related nuclear receptors involved in drug metabolism and play important roles in the mechanism of phenobarbital (PB)-induced rodent nongenotoxic hepatocarcinogenesis. Here, we have used a humanized CAR/PXR mouse model to examine potential species differences in receptor-dependent mechanisms underlying liver tissue molecular responses to PB. Early and late transcriptomic responses to sustained PB exposure were investigated in liver tissue from double knock-out CAR and PXR (CARᴷᴼ-PXRᴷᴼ), double humanized CAR and PXR (CARʰ-PXRʰ), and wild-type C57BL/6 mice. Wild-type and CARʰ-PXRʰ mouse livers exhibited temporally and quantitatively similar transcriptional responses during 91 days of PB exposure including the sustained induction of the xenobiotic response gene Cyp2b10, the Wnt signaling inhibitor Wisp1, and noncoding RNA biomarkers from the Dlk1-Dio3 locus. Transient induction of DNA replication (Hells, Mcm6, and Esco2) and mitotic genes (Ccnb2, Cdc20, and Cdk1) and the proliferation-related nuclear antigen Mki67 were observed with peak expression occurring between 1 and 7 days PB exposure. All these transcriptional responses were absent in CARᴷᴼ-PXRᴷᴼ mouse livers and largely reversible in wild-type and CARʰ-PXRʰ mouse livers following 91 days of PB exposure and a subsequent 4-week recovery period. Furthermore, PB-mediated upregulation of the noncoding RNA Meg3, which has recently been associated with cellular pluripotency, exhibited a similar dose response and perivenous hepatocyte-specific localization in both wild-type and CARʰ-PXRʰ mice. Thus, mouse livers coexpressing human CAR and PXR support both the xenobiotic metabolizing and the proliferative transcriptional responses following exposure to PB.},
  language  = {en}
}
@article{ScheerMclaughlinRodeetal.2014,
  author    = {Scheer, Nico and Mclaughlin, Lesley A. and Rode, Anja and MacLeod, Alastair Kenneth and Henderson, Colin J. and Wolf, Roland C.},
  title     = {Deletion of thirty murine cytochrome P450 genes results in viable mice with compromised drug metabolism},
  series = {Drug Metabolism and Disposition},
  volume    = {42},
  journal   = {Drug Metabolism and Disposition},
  number    = {6},
  publisher = {ASPET},
  address   = {Bethesda, Md.},
  issn      = {1521-009X},
  doi       = {10.1124/dmd.114.057885},
  pages     = {1022 -- 1030},
  year      = {2014},
  abstract  = {In humans, 75\% of all drugs are metabolized by the cytochrome P450-dependent monooxygenase system. Enzymes encoded by the CYP2C, CYP2D, and CYP3A gene clusters account for ∼80\% of this activity. There are profound species differences in the multiplicity of cytochrome P450 enzymes, and the use of mouse models to predict pathways of drug metabolism is further complicated by overlapping substrate specificity between enzymes from different gene families. To establish the role of the hepatic and extrahepatic P450 system in drug and foreign chemical disposition, drug efficacy, and toxicity, we created a unique mouse model in which 30 cytochrome P450 genes from the Cyp2c, Cyp2d, and Cyp3a gene clusters have been deleted. Remarkably, despite a wide range of putative important endogenous functions, Cyp2c/2d/3a KO mice were viable and fertile, demonstrating that these genes have evolved primarily as detoxification enzymes. Although there was no overt phenotype, detailed examination showed Cyp2c/2d/3a KO mice had a smaller body size (15\%) and larger livers (20\%). Changes in hepatic morphology and a decreased blood glucose (30\%) were also noted. A five-drug cocktail of cytochrome P450 isozyme probe substrates were used to evaluate changes in drug pharmacokinetics; marked changes were observed in either the pharmacokinetics or metabolites formed from Cyp2c, Cyp2d, and Cyp3a substrates, whereas the metabolism of the Cyp1a substrate caffeine was unchanged. Thus, Cyp2c/2d/3a KO mice provide a powerful model to study the in vivo role of the P450 system in drug metabolism and efficacy, as well as in chemical toxicity.},
  language  = {en}
}
@article{LevesqueSiegwolfEilmannetal.2014,
  author    = {L{\´e}vesque, Mathieu and Siegwolf, Rolf and Eilmann, Britta and Saurer, Matthias and Rigling, Andreas},
  title     = {Increased water-use efficiency does not lead to enhanced tree growth under xeric and mesic conditions},
  series = {New Phytologist},
  volume    = {203},
  journal   = {New Phytologist},
  number    = {1},
  publisher = {Wiley-Blackwell},
  address   = {Oxford},
  issn      = {1469-8137 (Online)},
  doi       = {10.1111/nph.12772},
  pages     = {94 -- 109},
  year      = {2014},
  language  = {en}
}
@article{HafnerDemetzWeickertetal.2014,
  author    = {Hafner, David and Demetz, Oliver and Weickert, Joachim and Reißel, Martin},
  title     = {Mathematical Foundations and Generalisations of the Census Transform for Robust Optic Flow Computation},
  series = {Journal of Mathematical Imaging and Vision},
  journal   = {Journal of Mathematical Imaging and Vision},
  publisher = {Springer},
  address   = {New York},
  issn      = {1573-7683 (Online)},
  doi       = {10.1007/s10851-014-0529-9},
  year      = {2014},
  language  = {en}
}
@inproceedings{GebhardtRitzSiekmannetal.2014,
  author    = {Gebhardt, Andreas and Ritz, Thomas and Siekmann, Kirsten and Wallenborn, Ramona},
  title     = {Additive manufacturing businesses in the process chain of individualized mass products},
  series = {DDMC 2014 : Proceedings of the Fraunhofer Direct Digital Manufacturing Conference},
  booktitle = {DDMC 2014 : Proceedings of the Fraunhofer Direct Digital Manufacturing Conference},
  editor    = {Demmer, Axel},
  publisher = {Fraunhofer},
  address   = {Stuttgart},
  isbn      = {978-3-8396-9128-1 (E-Book)},
  year      = {2014},
  language  = {en}
}
@misc{NoetzoldBragardFinketal.2014,
  author    = {N{\"o}tzold, K. and Bragard, Michael and Fink, K. and Griessel, R. and Wegener, R.},
  title     = {Cascaded H-bridge converter with transformer based cell power balancing in each voltage level : [Patentschrift]},
  publisher = {Europ{\"a}isches Patentamt / United States Patent and Trademark Office [u.a.]},
  address   = {Den Haag / Alexandria, VA},
  pages     = {16 S. : graph. Darst.},
  year      = {2014},
  language  = {en}
}
@inproceedings{Huening2014,
  author    = {H{\"u}ning, Felix},
  title     = {Power semiconductors : key components for HEV/EV},
  series = {FISITA 2014 World Automotive Congress : 2 - 6 June, Maastricht, the Netherlands International Federation of Automotive Engineering Societies},
  booktitle = {FISITA 2014 World Automotive Congress : 2 - 6 June, Maastricht, the Netherlands International Federation of Automotive Engineering Societies},
  publisher = {KIVI},
  address   = {[s.l.]},
  pages     = {1 USB-Speicherstick},
  year      = {2014},
  language  = {en}
}
@inproceedings{AlKaidyUlberTippkoetter2014,
  author    = {Al-Kaidy, Huschyar and Ulber, Roland and Tippk{\"o}tter, Nils},
  title     = {A platform technology for the automated reaction control in magnetizable micro-fluidic droplets},
  series = {Biomaterials - made in bioreactors : book of abstracts, May 26 - 28, 2014, Radisson Blu Park Hotel and Conference Dentre, Radebeul, Germany},
  booktitle = {Biomaterials - made in bioreactors : book of abstracts, May 26 - 28, 2014, Radisson Blu Park Hotel and Conference Dentre, Radebeul, Germany},
  publisher = {DECHEMA},
  address   = {Frankfurt am Main},
  pages     = {21 -- 22},
  year      = {2014},
  language  = {en}
}