@misc{JerominSeubertBeilharzetal.1988, author = {Jeromin, G{\"u}nter Erich and Seubert, Bernhard and Beilharz, Helmut and Fickert, Werner [u.a.]}, title = {Verfahren zur Herstellung von niedermolekularen Alkalihuminaten : Offenlegungsschrift DE3707910A1 ; Offenlegungstag: 22.09.1988 / Anmelder: R{\"u}tgerswerke AG, 6000 Frankfurt. Erfinder: Bernhard Seubert ; Helmut Beilharz ; Werner Fickert ; G{\"u}nter Jeromin ...}, publisher = {Deutsches Patent- und Markenamt}, address = {M{\"u}nchen}, pages = {4 S.}, year = {1988}, language = {de} } @misc{JerominSeubertBeilharzetal.1988, author = {Jeromin, G{\"u}nter Erich and Seubert, Bernhard and Beilharz, Helmut and Fickert, Werner [u.a.]}, title = {Niedermolekulare Alkalihuminate : Verfahren zu ihrer Herstellung und Verwendung ; Offenlegungsschrift DE3707909A1 ; Offenlegungstag: 22.09.1988 / Anmelder: R{\"u}tgerswerke AG, 6000 Frankfurt. Erfinder: Bernhard Seubert ; Helmut Beilharz ; Werner Fickert ; G{\"u}nter Jeromin ...}, publisher = {Deutsches Patent- und Markenamt}, address = {M{\"u}nchen}, pages = {4 S.}, year = {1988}, language = {de} } @misc{JerominSeubertBeilharzetal.1992, author = {Jeromin, G{\"u}nter Erich and Seubert, Bernhard and Beilharz, Helmut and Fickert, Werner [u.a.]}, title = {Wasserfreie Applikationsform niedermolekularer Alkalihuminate : Europ{\"a}ische Patentschrift EP0283573B1 ; Ver{\"o}ffentlichungstag im Patentblatt: 09.04.1992 / Anmelder: R{\"u}tgerswerke AG, 6000 Frankfurt. Erfinder: Bernhard Seubert ; Helmut Beilharz ; G{\"u}nter Jeromin ; Werner Fickert ...}, publisher = {Deutsches Patent- und Markenamt}, address = {M{\"u}nchen}, pages = {3 S.}, year = {1992}, language = {de} } @article{JerominWeise1990, author = {Jeromin, G{\"u}nter Erich and Weise, Sven}, title = {Enzymatische Acetylierung von (±)-1-Phthalimido-2-propanol}, series = {Liebigs Annalen der Chemie (1990)}, journal = {Liebigs Annalen der Chemie (1990)}, isbn = {0947-3440}, pages = {1045 -- 1046}, year = {1990}, language = {de} } @article{JerominWelsch1995, author = {Jeromin, G{\"u}nter Erich and Welsch, Volker}, title = {Diketene a New Esterification Reagent in the Enzyme-Aided Synthesis of Chiral Alcohols and Chiral Acetoacetic Acid Esters}, series = {Tetrahedron Letters . 36 (1995), H. 37}, journal = {Tetrahedron Letters . 36 (1995), H. 37}, isbn = {0040-4039}, pages = {6663 -- 6664}, year = {1995}, language = {en} } @article{JerominZoor2008, author = {Jeromin, G{\"u}nter Erich and Zoor, Annegreth}, title = {A new irreversible enzyme-aided esterification method in organic solvents}, series = {Biotechnology letters. 30 (2008), H. 5}, journal = {Biotechnology letters. 30 (2008), H. 5}, isbn = {1573-6776}, pages = {925 -- 928}, year = {2008}, language = {en} } @article{JordanKruegerWillmesetal.2011, author = {Jordan, Sabine D. and Kr{\"u}ger, Markus and Willmes, Diana M. and Redemann, Nora and Wunderlich, F. Thomas and Br{\"o}nneke, Hella S. and Merkwirth, Carsten and Kashkar, Hamid and Olkkonen, Vesa M. and B{\"o}ttger, Thomas and Braun, Thomas and Seibler, Jost and Br{\"u}ning, Jens C.}, title = {Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism}, series = {Nature Cell Biology}, volume = {13}, journal = {Nature Cell Biology}, number = {4}, publisher = {Nature}, address = {New York}, issn = {1465-7392}, doi = {10.1038/ncb2211}, pages = {434 -- 446}, year = {2011}, abstract = {The contribution of altered post-transcriptional gene silencing to the development of insulin resistance and type 2 diabetes mellitus so far remains elusive. Here, we demonstrate that expression of microRNA (miR)-143 and 145 is upregulated in the liver of genetic and dietary mouse models of obesity. Induced transgenic overexpression of miR-143, but not miR-145, impairs insulin-stimulated AKT activation and glucose homeostasis. Conversely, mice deficient for the miR-143-145 cluster are protected from the development of obesity-associated insulin resistance. Quantitative-mass-spectrometry-based analysis of hepatic protein expression in miR-143-overexpressing mice revealed miR-143-dependent downregulation of oxysterol-binding-protein-related protein (ORP) 8. Reduced ORP8 expression in cultured liver cells impairs the ability of insulin to induce AKT activation, revealing an ORP8-dependent mechanism of AKT regulation. Our experiments provide direct evidence that dysregulated post-transcriptional gene silencing contributes to the development of obesity-induced insulin resistance, and characterize the miR-143-ORP8 pathway as a potential target for the treatment of obesity-associated diabetes.}, language = {en} } @article{JossekBongaertsSprenger2001, author = {Jossek, Ralf and Bongaerts, Johannes and Sprenger, Georg A.}, title = {Characterization of a new feedback-resistant 3-deoxy-D-arabinoheptulosonate 7-phosphate synthase AroF of Escherichia coli}, series = {FEMS microbiology letters}, volume = {Vol. 202}, journal = {FEMS microbiology letters}, number = {Iss. 1}, issn = {1574-6968}, pages = {145 -- 148}, year = {2001}, language = {en} } @article{KalbeHoeckerBerndt1989, author = {Kalbe, Jochen and H{\"o}cker, Hartwig and Berndt, Heinz}, title = {Design of enzyme reactors as chromatographic columns for racemic resolution of amino acid esters}, series = {Chromatographia}, volume = {28}, journal = {Chromatographia}, number = {3-4}, isbn = {0009-5893}, doi = {10.1007/BF02319646}, pages = {193 -- 196}, year = {1989}, language = {en} } @article{KalbeKuropkaMeyerStorketal.1988, author = {Kalbe, Jochen and Kuropka, Rolf and Meyer-Stork, L. Sebastian and Berndt, Heinz and [u.a.],}, title = {Isolation and characterization of high-molecular mass DNA from hair shafts}, series = {Biological chemistry}, volume = {369}, journal = {Biological chemistry}, number = {1}, isbn = {0177-3593}, doi = {10.1515/bchm3.1988.369.1.413}, pages = {413 -- 416}, year = {1988}, language = {en} }