@article{SchollMoraisGabrieletal.2017, author = {Scholl, Fabio and Morais, Paulo and Gabriel, Rayla and Sch{\"o}ning, Michael Josef and Siqueira, Jose Roberto, Jr. and Caseli, Luciano}, title = {Carbon nanotubes arranged as smart interfaces in lipid Langmuir-Blodgett films enhancing the enzymatic properties of penicillinase for biosensing applications}, series = {Applied Materials \& Interfaces}, volume = {9}, journal = {Applied Materials \& Interfaces}, number = {36}, publisher = {ACS}, address = {Washington}, issn = {1944-8252}, doi = {10.1021/acsami.7b08095}, pages = {31054 -- 31066}, year = {2017}, abstract = {In this paper, carbon nanotubes (CNTs) were incorporated in penicillinase-phospholipid Langmuir and Langmuir-Blodgett (LB) films to enhance the enzyme catalytic properties. Adsorption of the penicillinase and CNTs at dimyristoylphosphatidic acid (DMPA) monolayers at the air-water interface was investigated by surface pressure-area isotherms, vibrational spectroscopy, and Brewster angle microscopy. The floating monolayers were transferred to solid supports through the LB technique, forming mixed DMPA-CNTs-PEN films, which were investigated by quartz crystal microbalance, vibrational spectroscopy, and atomic force microscopy. Enzyme activity was studied with UV-vis spectroscopy and the feasibility of the supramolecular device nanostructured as ultrathin films were essayed in a capacitive electrolyte-insulator-semiconductor (EIS) sensor device. The presence of CNTs in the enzyme-lipid LB film not only tuned the catalytic activity of penicillinase but also helped conserve its enzyme activity after weeks, showing increased values of activity. Viability as penicillin sensor was demonstrated with capacitance/voltage and constant capacitance measurements, exhibiting regular and distinctive output signals over all concentrations used in this work. These results may be related not only to the nanostructured system provided by the film, but also to the synergism between the compounds on the active layer, leading to a surface morphology that allowed a fast analyte diffusion because of an adequate molecular accommodation, which also preserved the penicillinase activity. This work therefore demonstrates the feasibility of employing LB films composed of lipids, CNTs, and enzymes as EIS devices for biosensing applications.}, language = {en} } @article{SchoenrockMuckeltHastermannetal.2024, author = {Schoenrock, Britt and Muckelt, Paul E. and Hastermann, Maria and Albracht, Kirsten and MacGregor, Robert and Martin, David and Gunga, Hans-Christian and Salanova, Michele and Stokes, Maria J. and Warner, Martin B. and Blottner, Dieter}, title = {Muscle stiffness indicating mission crew health in space}, series = {Scientific Reports}, volume = {14}, journal = {Scientific Reports}, number = {Article number: 4196}, publisher = {Springer Nature}, address = {London}, issn = {2045-2322}, doi = {10.1038/s41598-024-54759-6}, pages = {13 Seiten}, year = {2024}, abstract = {Muscle function is compromised by gravitational unloading in space affecting overall musculoskeletal health. Astronauts perform daily exercise programmes to mitigate these effects but knowing which muscles to target would optimise effectiveness. Accurate inflight assessment to inform exercise programmes is critical due to lack of technologies suitable for spaceflight. Changes in mechanical properties indicate muscle health status and can be measured rapidly and non-invasively using novel technology. A hand-held MyotonPRO device enabled monitoring of muscle health for the first time in spaceflight (> 180 days). Greater/maintained stiffness indicated countermeasures were effective. Tissue stiffness was preserved in the majority of muscles (neck, shoulder, back, thigh) but Tibialis Anterior (foot lever muscle) stiffness decreased inflight vs. preflight (p < 0.0001; mean difference 149 N/m) in all 12 crewmembers. The calf muscles showed opposing effects, Gastrocnemius increasing in stiffness Soleus decreasing. Selective stiffness decrements indicate lack of preservation despite daily inflight countermeasures. This calls for more targeted exercises for lower leg muscles with vital roles as ankle joint stabilizers and in gait. Muscle stiffness is a digital biomarker for risk monitoring during future planetary explorations (Moon, Mars), for healthcare management in challenging environments or clinical disorders in people on Earth, to enable effective tailored exercise programmes.}, language = {en} } @inproceedings{SchneiderAlHakimKayseretal.2017, author = {Schneider, Oliver and Al Hakim, Taher and Kayser, Peter and Digel, Ilya}, title = {Development and trials of a test chamber for ultrasound-assisted sampling of living cells from solid surfaces}, series = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, booktitle = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, editor = {Erni, Daniel and Fischerauer, Alice and Himmel, J{\"o}rg and Seeger, Thomas and Thelen, Klaus}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-9814801-9-1}, doi = {10.17185/duepublico/43984}, pages = {96 -- 97}, year = {2017}, language = {en} } @inproceedings{SchmitzApandiSpillneretal.2024, author = {Schmitz, Annika and Apandi, Shah Eiman Amzar Shah and Spillner, Jan and Hima, Flutura and Behbahani, Mehdi}, title = {Effect of different cannula positions in the pulmonary artery on blood flow and gas exchange using computational fluid dynamics analysis}, series = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen}, booktitle = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen}, editor = {Digel, Ilya and Staat, Manfred and Trzewik, J{\"u}rgen and Sielemann, Stefanie and Erni, Daniel and Zylka, Waldemar}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-65-3}, doi = {10.17185/duepublico/81475}, pages = {29 -- 30}, year = {2024}, abstract = {Pulmonary arterial cannulation is a common and effective method for percutaneous mechanical circulatory support for concurrent right heart and respiratory failure [1]. However, limited data exists to what effect the positioning of the cannula has on the oxygen perfusion throughout the pulmonary artery (PA). This study aims to evaluate, using computational fluid dynamics (CFD), the effect of different cannula positions in the PA with respect to the oxygenation of the different branching vessels in order for an optimal cannula position to be determined. The four chosen different positions (see Fig. 1) of the cannulas are, in the lower part of the main pulmonary artery (MPA), in the MPA at the junction between the right pulmonary artery (RPA) and the left pulmonary artery (LPA), in the RPA at the first branch of the RPA and in the LPA at the first branch of the LPA.}, language = {en} } @article{SchmittWernerSchoening2002, author = {Schmitt, G. and Werner, C. and Sch{\"o}ning, Michael Josef}, title = {Microelectrochemical efficiency evaluation of inhibitors for CO2 corrosion of carbon steel under high shear stress gradients}, series = {Corrosion 2002. Conference Proceedings. NACExpo, 57th Annual Conference and Exhibition, Denver, US, Apr 7-11, 2002}, journal = {Corrosion 2002. Conference Proceedings. NACExpo, 57th Annual Conference and Exhibition, Denver, US, Apr 7-11, 2002}, publisher = {NACE International}, address = {Houston, Texas}, pages = {1 -- 11}, year = {2002}, language = {en} } @article{SchmittSchultzeFassbenderetal.1999, author = {Schmitt, G. and Schultze, J.-W. and Faßbender, F. and Buß, G. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef}, title = {Passivation and corrosion of microelectrode arrays}, series = {Electrochimica Acta. 44 (1999), H. 21-22}, journal = {Electrochimica Acta. 44 (1999), H. 21-22}, isbn = {0013-4686}, pages = {3865 -- 3883}, year = {1999}, language = {en} } @article{SchmittFassbenderLuethetal.2000, author = {Schmitt, G. and Faßbender, F. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef and Schultze, J. W. and Buß, G.}, title = {Passivation and corrosion of microelectrode arrays}, series = {Materials and Corrosion. 51 (2000), H. 1}, journal = {Materials and Corrosion. 51 (2000), H. 1}, isbn = {0947-5117}, pages = {20 -- 25}, year = {2000}, language = {en} } @inproceedings{SchmidtsKraftWinkensetal.2020, author = {Schmidts, Oliver and Kraft, Bodo and Winkens, Marvin and Z{\"u}ndorf, Albert}, title = {Catalog integration of low-quality product data by attribute label ranking}, series = {Proceedings of the 9th International Conference on Data Science, Technology and Applications - Volume 1: DATA}, booktitle = {Proceedings of the 9th International Conference on Data Science, Technology and Applications - Volume 1: DATA}, isbn = {978-989-758-440-4}, doi = {10.5220/0009831000900101}, pages = {90 -- 101}, year = {2020}, language = {en} } @inproceedings{SchmidtsKraftWinkensetal.2021, author = {Schmidts, Oliver and Kraft, Bodo and Winkens, Marvin and Z{\"u}ndorf, Albert}, title = {Catalog integration of heterogeneous and volatile product data}, series = {DATA 2020: Data Management Technologies and Applications}, booktitle = {DATA 2020: Data Management Technologies and Applications}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-83013-7}, doi = {10.1007/978-3-030-83014-4_7}, pages = {134 -- 153}, year = {2021}, abstract = {The integration of frequently changing, volatile product data from different manufacturers into a single catalog is a significant challenge for small and medium-sized e-commerce companies. They rely on timely integrating product data to present them aggregated in an online shop without knowing format specifications, concept understanding of manufacturers, and data quality. Furthermore, format, concepts, and data quality may change at any time. Consequently, integrating product catalogs into a single standardized catalog is often a laborious manual task. Current strategies to streamline or automate catalog integration use techniques based on machine learning, word vectorization, or semantic similarity. However, most approaches struggle with low-quality or real-world data. We propose Attribute Label Ranking (ALR) as a recommendation engine to simplify the integration process of previously unknown, proprietary tabular format into a standardized catalog for practitioners. We evaluate ALR by focusing on the impact of different neural network architectures, language features, and semantic similarity. Additionally, we consider metrics for industrial application and present the impact of ALR in production and its limitations.}, language = {en} } @inproceedings{SchmidtsKraftSiebigterothetal.2019, author = {Schmidts, Oliver and Kraft, Bodo and Siebigteroth, Ines and Z{\"u}ndorf, Albert}, title = {Schema Matching with Frequent Changes on Semi-Structured Input Files: A Machine Learning Approach on Biological Product Data}, series = {Proceedings of the 21st International Conference on Enterprise Information Systems - Volume 1: ICEIS}, booktitle = {Proceedings of the 21st International Conference on Enterprise Information Systems - Volume 1: ICEIS}, isbn = {978-989-758-372-8}, doi = {10.5220/0007723602080215}, pages = {208 -- 215}, year = {2019}, language = {en} }