@article{KallweitKorculaninFroehligetal.2011, author = {Kallweit, Stephan and Korculanin, O. and Fr{\"o}hlig, F. and Gabi, M. and Mattern, P.}, title = {Photogrammetrische Rekonstruktion von Partikelpositionen mittels R{\"u}ckprojektion f{\"u}r 3D-PIV}, series = {Lasermethoden in der Str{\"o}mungsmesstechnik : 19. Fachtagung, 6. - 8. September 2011, Ilmenau ; [Tagungsband enth{\"a}lt ... Beitr{\"a}ge, die anl{\"a}sslich der 19. Fachtagaung "Lasermethoden in der Str{\"o}mungsmesstechnik" ... vorgetragen und diskutiert wurden] / veranst. von der Deutschen Gesellschaft f{\"u}r Laser-Anemometrie GALA e.V. Hrsg. A. Thess...}, journal = {Lasermethoden in der Str{\"o}mungsmesstechnik : 19. Fachtagung, 6. - 8. September 2011, Ilmenau ; [Tagungsband enth{\"a}lt ... Beitr{\"a}ge, die anl{\"a}sslich der 19. Fachtagaung "Lasermethoden in der Str{\"o}mungsmesstechnik" ... vorgetragen und diskutiert wurden] / veranst. von der Deutschen Gesellschaft f{\"u}r Laser-Anemometrie GALA e.V. Hrsg. A. Thess...}, publisher = {Dt. Ges. f{\"u}r Laser-AnemometrieGALA e. V.}, address = {Karlsruhe}, isbn = {978-3-9805613-7-2}, pages = {28/1 -- 28/6}, year = {2011}, language = {de} } @article{JordanKruegerWillmesetal.2011, author = {Jordan, Sabine D. and Kr{\"u}ger, Markus and Willmes, Diana M. and Redemann, Nora and Wunderlich, F. Thomas and Br{\"o}nneke, Hella S. and Merkwirth, Carsten and Kashkar, Hamid and Olkkonen, Vesa M. and B{\"o}ttger, Thomas and Braun, Thomas and Seibler, Jost and Br{\"u}ning, Jens C.}, title = {Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism}, series = {Nature Cell Biology}, volume = {13}, journal = {Nature Cell Biology}, number = {4}, publisher = {Nature}, address = {New York}, issn = {1465-7392}, doi = {10.1038/ncb2211}, pages = {434 -- 446}, year = {2011}, abstract = {The contribution of altered post-transcriptional gene silencing to the development of insulin resistance and type 2 diabetes mellitus so far remains elusive. Here, we demonstrate that expression of microRNA (miR)-143 and 145 is upregulated in the liver of genetic and dietary mouse models of obesity. Induced transgenic overexpression of miR-143, but not miR-145, impairs insulin-stimulated AKT activation and glucose homeostasis. Conversely, mice deficient for the miR-143-145 cluster are protected from the development of obesity-associated insulin resistance. Quantitative-mass-spectrometry-based analysis of hepatic protein expression in miR-143-overexpressing mice revealed miR-143-dependent downregulation of oxysterol-binding-protein-related protein (ORP) 8. Reduced ORP8 expression in cultured liver cells impairs the ability of insulin to induce AKT activation, revealing an ORP8-dependent mechanism of AKT regulation. Our experiments provide direct evidence that dysregulated post-transcriptional gene silencing contributes to the development of obesity-induced insulin resistance, and characterize the miR-143-ORP8 pathway as a potential target for the treatment of obesity-associated diabetes.}, language = {en} } @article{InagakiSleddensLinkelsWassenaaretal.2011, author = {Inagaki, Akiko and Sleddens-Linkels, Esther and Wassenaar, Evelyne and Ooms, Marja and Cappellen, Wiggert A. van and Hoeijmakers, Jan H. J. and Seibler, Jost and Vogt, Thomas F. and Shin, Myung K. and Grootegoed, J. Anton and Baarends, Willy M.}, title = {Meiotic functions of RAD18}, series = {Journal of Cell Science}, volume = {124}, journal = {Journal of Cell Science}, number = {16}, publisher = {Company of Biologists Limited}, address = {Cambridge}, issn = {1477-9137}, doi = {10.1242/jcs.081968}, pages = {2837 -- 2850}, year = {2011}, language = {en} } @article{ImmelGrothHuhnetal.2011, author = {Immel, Timo A. and Groth, Ulrich and Huhn, Thomas and {\"O}hlschl{\"a}ger, Peter}, title = {Titanium salan complexes displays strong antitumor properties in vitro and in vivo in mice}, series = {PLoS ONE}, volume = {6}, journal = {PLoS ONE}, number = {3}, publisher = {Plos}, address = {San Francisco, California, US}, doi = {10.1371/journal.pone.0017869}, pages = {e17869}, year = {2011}, abstract = {The anticancer activity of titanium complexes has been known since the groundbreaking studies of K{\"o}pf and K{\"o}pf-Maier on titanocen dichloride. Unfortunately, possibly due to their fast hydrolysis, derivatives of titanocen dichloride failed in clinical studies. Recently, the new family of titanium salan complexes containing tetradentate ONNO ligands with anti-cancer properties has been discovered. These salan complexes are much more stabile in aqueous media. In this study we describe the biological activity of two titanium salan complexes in a mouse model of cervical cancer. High efficiency of this promising complex family was demonstrated for the first time in vivo. From these data we conclude that titanium salan complexes display very strong antitumor properties exhibiting only minor side effects. Our results may influence the chemotherapy with metallo therapeutics in the future.}, language = {en} } @article{Huening2011, author = {H{\"u}ning, Felix}, title = {PowerMOSFETs in ANL2-Technologie : Ansteuerungen bis in den kW-Bereich mit wenig Verlustleistung und Platzbedarf}, series = {Elektronik-Industrie}, volume = {42}, journal = {Elektronik-Industrie}, number = {10}, publisher = {H{\"u}thig}, address = {Heidelberg}, issn = {0174-5522}, pages = {36 -- 39}, year = {2011}, language = {de} } @inproceedings{HoettgesRolfingSiekeretal.2011, author = {H{\"o}ttges, J{\"o}rg and Rolfing, Richard and Sieker, Heiko and Siekmann, Marko and Wermter, Paul}, title = {GIS-gest{\"u}tzte Erstellung von Niederschlagswasserbeseitigungskonzepten}, series = {12. K{\"o}lner Kanal- und Kl{\"a}ranlagen-Kolloquium : 13. und 14. Oktober 2011 im Maternushaus, K{\"o}ln / ISA, Institut und Lehrstuhl f{\"u}r Siedlungswasserwirtschaft}, booktitle = {12. K{\"o}lner Kanal- und Kl{\"a}ranlagen-Kolloquium : 13. und 14. Oktober 2011 im Maternushaus, K{\"o}ln / ISA, Institut und Lehrstuhl f{\"u}r Siedlungswasserwirtschaft}, editor = {Pinnekamp, Johannes}, publisher = {Ges. zur F{\"o}rderung der Siedlungswasserwirtschaft an der RWTH Aachen}, address = {Aachen}, isbn = {978-3-938996-08-9}, pages = {8/1 -- 8/13}, year = {2011}, language = {de} } @inproceedings{Hoettges2011, author = {H{\"o}ttges, J{\"o}rg}, title = {GIS-gest{\"u}tzte Niederschlagswasserbeseitigungskonzepte - Aufgaben und Inhalte}, series = {44. Essener Tagung f{\"u}r Wasser- und Abfallwirtschaft : "zukunftsf{\"a}hige Wasserwirtschaft - kosteneffizient und energiebewusst"; 23. bis 25. M{\"a}rz 2011 im Eurogress Aachen}, booktitle = {44. Essener Tagung f{\"u}r Wasser- und Abfallwirtschaft : "zukunftsf{\"a}hige Wasserwirtschaft - kosteneffizient und energiebewusst"; 23. bis 25. M{\"a}rz 2011 im Eurogress Aachen}, editor = {Pinnekamp, Johannes}, publisher = {Ges. zur F{\"o}rderung der Siedlungswasserwirtschaft an der RWTH Aachen}, address = {Aachen}, isbn = {978-3-938996-29-4}, pages = {29/1 -- 29/14}, year = {2011}, language = {de} } @article{HuckJollyWagneretal.2011, author = {Huck, Christina and Jolly, Christina and Wagner, Patrick and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {One-chip integrated dual amperometric/field-effect sensor for the detection of dissolved hydrogen}, series = {Procedia Engineering. 25 (2011)}, journal = {Procedia Engineering. 25 (2011)}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {1877-7058}, pages = {1161 -- 1164}, year = {2011}, language = {en} } @inproceedings{HuckBaeckerPoghossianetal.2011, author = {Huck, Christina and B{\"a}cker, Matthias and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Bifunktionaler Sensorchip f{\"u}r den Nachweis von Gel{\"o}stwasserstoff}, isbn = {978-3942710-53-4}, doi = {10.5162/10dss2011/16.10}, pages = {325 -- 328}, year = {2011}, language = {de} } @inproceedings{HuberBleckScheiketal.2011, author = {Huber, Fr{\´e}d{\´e}ric and Bleck, Wolfgang and Scheik, Sven and Schleser, Markus and Reisgen, Uwe}, title = {Investigation of galvanneal coating adherence in adhesive bonded joints using lap shear test}, series = {Galvatech 2011 : 8th International Conference on Zinc and Zinc Alloy Coated Steel Sheet, June 21 - 24, 2011, Genova (Italy) ; proceedings}, booktitle = {Galvatech 2011 : 8th International Conference on Zinc and Zinc Alloy Coated Steel Sheet, June 21 - 24, 2011, Genova (Italy) ; proceedings}, publisher = {Associazione Italiana di Metallurgia}, address = {Mailand}, organization = {International Conference on Zinc and Zinc Alloy Coated Steel Sheet <8, 2011, Genua>}, isbn = {978-88-85298-82-8}, pages = {Paper No. 43}, year = {2011}, language = {en} }