@misc{BesslerMaurerMerkeletal.2009, author = {Bessler, Cornelius and Maurer, Karl-Heinz and Merkel, Marion and Siegert, Petra and Wieland, Susanne}, title = {Subtilisin from Bacillus Pumilus and detergent and cleaning agents containing said novel subtilisin [US Patentanmeldung / Internationale Patentanmeldung]}, publisher = {USPTO; WIPO}, address = {Washington; Genf}, pages = {1 -- 39}, year = {2009}, language = {en} } @misc{BesslerMaurerMerkeletal.2007, author = {Bessler, Cornelius and Maurer, Karl-Heinz and Merkel, Marion and Siegert, Petra and Wieland, Susanne}, title = {Subtilisin aus Bacillus pumilus und Wasch- und Reinigungsmittel enthaltend dieses neue Subtilisin [Offenlegungsschrift]}, publisher = {Deutsches Patent- und Markenamt / Europ{\"a}isches Patentamt / WIPO / CIPO}, address = {M{\"u}nchen / Den Hague / Genf}, pages = {1 -- 47}, year = {2007}, language = {de} } @misc{BesslerEversMaureretal.2009, author = {Bessler, Cornelius and Evers, Stefan and Maurer, Karl-Heinz and Merkel, Marion and Siegert, Petra and Weber, Angrit and Wieland, Susanne}, title = {Leistungsverbesserte Proteasen und Wasch- und Reinigungsmittel enthaltend diese Proteasen [Offenlegungsschrift]}, publisher = {Deutsches Patent- und Markenamt / WIPO}, address = {M{\"u}nchen / Genf}, pages = {1 -- 41}, year = {2009}, language = {de} } @masterthesis{Berwanger2024, type = {Bachelor Thesis}, author = {Berwanger, Natalie}, title = {Social Media Kampagne - Produktwerbung : Videobegleitende Social Media Kampagne zur Vermarktung eines Produkts}, publisher = {FH Aachen}, address = {Aachen}, pages = {37 Seiten}, year = {2024}, abstract = {Diese zweiw{\"o}chige Social Media Kampagne pr{\"a}sentiert ein Auto durch eine Fusion von realer und digitaler Kunst, unterst{\"u}tzt von audiovisuellen Elementen. Ziel ist es, ein neues Erlebnis zu schaffen, das nachhaltige Mobilit{\"a}t in st{\"a}dtischer Kultur reflektiert und fortschrittliche Technologien nutzt.}, language = {de} } @article{BertzSchoeningMolinnusetal.2024, author = {Bertz, Morten and Sch{\"o}ning, Michael Josef and Molinnus, Denise and Homma, Takayuki}, title = {Influence of temperature, light, and H₂O₂ concentration on microbial spore inactivation: in-situ Raman spectroscopy combined with optical trapping}, series = {Physica status solidi (a) applications and materials science}, journal = {Physica status solidi (a) applications and materials science}, number = {Early View}, publisher = {Wiley-VCH}, address = {Berlin}, issn = {1862-6319 (Online)}, doi = {10.1002/pssa.202300866}, pages = {8 Seiten}, year = {2024}, abstract = {To gain insight on chemical sterilization processes, the influence of temperature (up to 70 °C), intense green light, and hydrogen peroxide (H₂O₂) concentration (up to 30\% in aqueous solution) on microbial spore inactivation is evaluated by in-situ Raman spectroscopy with an optical trap. Bacillus atrophaeus is utilized as a model organism. Individual spores are isolated and their chemical makeup is monitored under dynamically changing conditions (temperature, light, and H₂O₂ concentration) to mimic industrially relevant process parameters for sterilization in the field of aseptic food processing. While isolated spores in water are highly stable, even at elevated temperatures of 70 °C, exposure to H₂O₂ leads to a loss of spore integrity characterized by the release of the key spore biomarker dipicolinic acid (DPA) in a concentration-dependent manner, which indicates damage to the inner membrane of the spore. Intensive light or heat, both of which accelerate the decomposition of H₂O₂ into reactive oxygen species (ROS), drastically shorten the spore lifetime, suggesting the formation of ROS as a rate-limiting step during sterilization. It is concluded that Raman spectroscopy can deliver mechanistic insight into the mode of action of H₂O₂-based sterilization and reveal the individual contributions of different sterilization methods acting in tandem.}, language = {en} } @article{BertzMolinnusSchoeningetal.2023, author = {Bertz, Morten and Molinnus, Denise and Sch{\"o}ning, Michael Josef and Homma, Takayuki}, title = {Real-time monitoring of H₂O₂ sterilization on individual bacillus atrophaeus spores by optical sensing with trapping Raman spectroscopy}, series = {Chemosensors}, volume = {8}, journal = {Chemosensors}, number = {11}, publisher = {MDPI}, address = {Basel}, issn = {2227-9040}, doi = {10.3390/chemosensors11080445}, pages = {Artikel 445}, year = {2023}, abstract = {Hydrogen peroxide (H₂O₂), a strong oxidizer, is a commonly used sterilization agent employed during aseptic food processing and medical applications. To assess the sterilization efficiency with H₂O₂, bacterial spores are common microbial systems due to their remarkable robustness against a wide variety of decontamination strategies. Despite their widespread use, there is, however, only little information about the detailed time-resolved mechanism underlying the oxidative spore death by H₂O₂. In this work, we investigate chemical and morphological changes of individual Bacillus atrophaeus spores undergoing oxidative damage using optical sensing with trapping Raman microscopy in real-time. The time-resolved experiments reveal that spore death involves two distinct phases: (i) an initial phase dominated by the fast release of dipicolinic acid (DPA), a major spore biomarker, which indicates the rupture of the spore's core; and (ii) the oxidation of the remaining spore material resulting in the subsequent fragmentation of the spores' coat. Simultaneous observation of the spore morphology by optical microscopy corroborates these mechanisms. The dependence of the onset of DPA release and the time constant of spore fragmentation on H₂O₂ shows that the formation of reactive oxygen species from H₂O₂ is the rate-limiting factor of oxidative spore death.}, language = {en} } @inproceedings{BertschMeineckeWolfetal.2019, author = {Bertsch, Timo and Meinecke, Matthias and Wolf, Martin R. and Schmunk, Karina}, title = {Smart-Living-Services nur gegen Daten? Process-Mining als M{\"o}glichkeit zur Steigerung der Akzeptanz!}, series = {Angewandte Forschung in der Wirtschaftsinformatik 2019 : Tagungsband zur 32. AKWI-Jahrestagung / hrsg. von Martin R. Wolf, Thomas Barton, Frank Herrmann, Vera G. Meister, Christian M{\"u}ller, Christian Seel}, booktitle = {Angewandte Forschung in der Wirtschaftsinformatik 2019 : Tagungsband zur 32. AKWI-Jahrestagung / hrsg. von Martin R. Wolf, Thomas Barton, Frank Herrmann, Vera G. Meister, Christian M{\"u}ller, Christian Seel}, publisher = {mana-Buch}, address = {Heide}, isbn = {978-3-944330-62-4}, pages = {216 -- 226}, year = {2019}, abstract = {Seit Jahren etablieren sich Technologien in unserem Alltag, die mit Hilfe von smarten Komponenten neue Services und Vernetzungsm{\"o}glichkeiten schaffen. Dieses Paper beschreibt die Ergebnisse einer Studie, die die Akzeptanz von IoT-gest{\"u}tzten, smarten Services im privaten Umfeld untersucht. Dabei wird eine zentrale Datenverarbeitung mit automatisierter Erstellung smarter Services der dezentralen Datenverarbeitung mit manueller Serviceerstellung in sieben Kategorien gegen{\"u}bergestellt. Die Auswertung der Studie legt die Forschungsfrage nahe, ob das Nutzerverhalten im Kontext Smart Living nicht auch mit einem dezentralen L{\"o}sungsansatz, und somit unabh{\"a}ngig von großen Unternehmen, analysiert werden kann. Hierf{\"u}r wird im zweiten Teil des Papers die Anwendbarkeit von Process-Mining im Bereich Smart Living untersucht und prototypisch getestet.}, language = {de} } @article{BerretzSkorupaSanderetal.2011, author = {Berretz, Frank and Skorupa, Sasche and Sander, Volker and Belloum, Adam and Bubak, Marian}, title = {Actor-Driven Workflow Execution in Distributed Environments}, series = {Euro-Par 2010 Parallel Processing Workshops : HeteroPAR, HPCC, HiBB, CoreGrid, UCHPC, HPCF, PROPER, CCPI, VHPC ; Ischia, Italy, August 31 - September 3, 2010 ; revised selected papers / Mario R. Guarracino ... (eds.)}, journal = {Euro-Par 2010 Parallel Processing Workshops : HeteroPAR, HPCC, HiBB, CoreGrid, UCHPC, HPCF, PROPER, CCPI, VHPC ; Ischia, Italy, August 31 - September 3, 2010 ; revised selected papers / Mario R. Guarracino ... (eds.)}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-642-21877-4}, pages = {287 -- 294}, year = {2011}, language = {en} } @article{BerretzSkorupaSanderetal.2010, author = {Berretz, F. and Skorupa, S. and Sander, Volker and Belloum, A.}, title = {Towards an actor-driven workflow management system for grids}, series = {International Symposium on Collaborative Technologies and Systems (CTS), 2010 : 17 - 21 May 2010, Chicago, Illinois, USA / IEEE}, journal = {International Symposium on Collaborative Technologies and Systems (CTS), 2010 : 17 - 21 May 2010, Chicago, Illinois, USA / IEEE}, publisher = {IEEE}, address = {Piscataway, NJ}, isbn = {978-1-4244-6619-1}, pages = {611 -- 616}, year = {2010}, language = {en} } @article{BerneckerKlierSternetal.2018, author = {Bernecker, Andreas and Klier, Julia and Stern, Sebastian and Thiel, Lea}, title = {Sustaining high performance beyond public-sector pilot projects.}, number = {September 2018}, organization = {McKinsey\&Company}, year = {2018}, language = {en} }