@incollection{Schloesser2016, author = {Schl{\"o}sser, Karl Helmut}, title = {Baukosten und Finanzierung}, series = {Zahlentafeln f{\"u}r den Baubetrieb}, booktitle = {Zahlentafeln f{\"u}r den Baubetrieb}, edition = {9., {\"u}berarb. und aktual. Aufl.}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-02838-1 (Online)}, doi = {10.1007/978-3-658-02838-1_5}, pages = {423 -- 634}, year = {2016}, language = {de} } @incollection{Schloesser2016, author = {Schl{\"o}sser, Karl Helmut}, title = {Leistungsbeschreibung und Bauvertrag}, series = {Zahlentafeln f{\"u}r den Baubetrieb}, booktitle = {Zahlentafeln f{\"u}r den Baubetrieb}, edition = {9., {\"u}berarb. und aktual. Aufl.}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-02838-1 (Online)}, doi = {10.1007/978-3-658-02838-1_6}, pages = {635 -- 961}, year = {2016}, abstract = {Das Gesetz gegen Wettbewerbsbeschr{\"a}nkungen bildet die Grundlage f{\"u}r die Verordnung {\"u}ber die Vergabe {\"o}ffentlicher Auftr{\"a}ge, aus der sich die Vergabe- und Vertragsordnungen f{\"u}r Freiberufliche Leistungen (VOF), f{\"u}r Lieferungen und Leistungen (VOL) und f{\"u}r Bauleistungen (VOB) ableiten. Die dabei in Frage kommenden Vergabeverfahren und die einzelnen Schwellenwerte gem{\"a}ß EU-Recht werden detailliert aufbereitet und im Zusammenhang dargestellt. Die f{\"u}r die Ausgestaltung von Bauvertr{\"a}gen notwendigen Grundlagen des Werkvertragsrecht nach BGB sowie die branchenspezifischen Allgemeinen Gesch{\"a}ftsbedingungen in Form der Vertragsordnung f{\"u}r Bauleistungen (VOB) mit ihren Zus{\"a}tzlichen und Besonderen Vertragsbedingungen werden intensiv aufbereitet. Das Zustandekommen eines Bauvertrages ergibt sich dann aus der notwendigen Leistungsbeschreibung mit einem Leistungsverzeichnis und verschiedenen Positionen oder in Form einer Funktionalen Leistungsbeschreibung (Beschreibung mit Leistungsprogramm). Das Auslandsgesch{\"a}ft der Baubranche (Bauausf{\"u}hrende Unternehmen sowie Beratende Ingenieure und Consultants) wird von den jeweils vorliegenden Internationalen Wettbewerbsbedingungen bestimmt, deren Zusammenh{\"a}nge anhand umfangreicher statistischer Daten und anhand von Beispielen dargestellt werden.}, language = {de} } @inproceedings{SchleupenEngemannBagherietal.2016, author = {Schleupen, Josef and Engemann, Heiko and Bagheri, Mohsen and Kallweit, Stephan}, title = {The potential of SMART climbing robot combined with a weatherproof cabin for rotor blade maintenance}, series = {17th European Conference on Composite Materials - ECCM, Munich, Germany}, booktitle = {17th European Conference on Composite Materials - ECCM, Munich, Germany}, pages = {1 -- 8}, year = {2016}, language = {en} } @article{SchifferFerrein2016, author = {Schiffer, Stefan and Ferrein, Alexander}, title = {Decision-Theoretic Planning with Fuzzy Notions in GOLOG}, series = {International Journal of Uncertainty, Fuzziness and Knowledge-Based Systems}, volume = {24}, journal = {International Journal of Uncertainty, Fuzziness and Knowledge-Based Systems}, number = {Issue Suppl. 2}, publisher = {World Scientific}, address = {Singapur}, issn = {1793-6411}, doi = {10.1142/S0218488516400134}, pages = {123 -- 143}, year = {2016}, abstract = {In this paper we present an extension of the action language Golog that allows for using fuzzy notions in non-deterministic argument choices and the reward function in decision-theoretic planning. Often, in decision-theoretic planning, it is cumbersome to specify the set of values to pick from in the non-deterministic-choice-of-argument statement. Also, even for domain experts, it is not always easy to specify a reward function. Instead of providing a finite domain for values in the non-deterministic-choice-of-argument statement in Golog, we now allow for stating the argument domain by simply providing a formula over linguistic terms and fuzzy uents. In Golog's forward-search DT planning algorithm, these formulas are evaluated in order to find the agent's optimal policy. We illustrate this in the Diner Domain where the agent needs to calculate the optimal serving order.}, language = {en} } @article{ScheidweilerTriesch2016, author = {Scheidweiler, Robert and Triesch, Eberhard}, title = {A note on the duality between matchings and vertex covers in balanced hypergraphs}, series = {Journal of Combinatorial Optimization}, volume = {32}, journal = {Journal of Combinatorial Optimization}, number = {2}, publisher = {Springer}, address = {Berlin}, issn = {1573-2886}, doi = {10.1007/s10878-015-9887-5}, pages = {639 -- 644}, year = {2016}, abstract = {We present a new Min-Max theorem for an optimization problem closely connected to matchings and vertex covers in balanced hypergraphs. The result generalizes Kőnig's Theorem (Berge and Las Vergnas in Ann N Y Acad Sci 175:32-40, 1970; Fulkerson et al. in Math Progr Study 1:120-132, 1974) and Hall's Theorem (Conforti et al. in Combinatorica 16:325-329, 1996) for balanced hypergraphs.}, language = {en} } @article{ScheerWilson2016, author = {Scheer, Nico and Wilson, Ian D.}, title = {A comparison between genetically humanized and chimeric liver humanized mouse models for studies in drug metabolism and toxicity}, series = {Drug Discovery Today}, volume = {21}, journal = {Drug Discovery Today}, number = {2}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1359-6446}, doi = {10.1016/j.drudis.2015.09.002}, pages = {250 -- 263}, year = {2016}, abstract = {Mice that have been genetically humanized for proteins involved in drug metabolism and toxicity and mice engrafted with human hepatocytes are emerging and promising in vivo models for an improved prediction of the pharmacokinetic, drug-drug interaction and safety characteristics of compounds in humans. The specific advantages and disadvantages of these models should be carefully considered when using them for studies in drug discovery and development. Here, an overview on the corresponding genetically humanized and chimeric liver humanized mouse models described to date is provided and illustrated with examples of their utility in drug metabolism and toxicity studies. We compare the strength and weaknesses of the two different approaches, give guidance for the selection of the appropriate model for various applications and discuss future trends and perspectives.}, language = {en} } @incollection{ScheerChuSalphatietal.2016, author = {Scheer, Nico and Chu, Xiaoyan and Salphati, Laurent and Zamek-Gliszczynski, Maciej J.}, title = {Knockout and humanized animal models to study membrane transporters in drug development}, series = {Drug Transporters: Volume 1: Role and Importance in ADME and Drug Development}, booktitle = {Drug Transporters: Volume 1: Role and Importance in ADME and Drug Development}, editor = {Nicholls, Glynis}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, isbn = {978-1-78262-379-3}, doi = {10.1039/9781782623793-00298}, pages = {298 -- 332}, year = {2016}, language = {en} } @techreport{SansomLawsonTuchoetal.2016, author = {Sansom, M. and Lawson, R.M. and Tucho, R. and Kendrick, C. and Ogden, R. and Resalati, S. and Garay, R. and D{\"o}ring, Bernd and Reger, V. and Gilbert, J. and Heikkinen, J. and Hemmila, K.}, title = {Building in active thermal mass into steel structures (BATIMASS) - EUR 28166EN}, publisher = {Publications Office of the European Union}, address = {Luxembourg}, organization = {European Commission}, isbn = {978-92-79-63176-4}, issn = {1831-9424}, doi = {10.2777/25999}, pages = {147 Seiten}, year = {2016}, abstract = {The main objective of the BATIMASS project was to address how the energy balance in relatively lightweight steel buildings can be improved by building in 'active thermal mass' (ATM) into the building fabric. This was achieved through concept design, dynamic thermal modelling and testing of a number of potentially viable systems and concepts. A significant programme of thermal simulation modelling was undertaken utilising the thermally equivalent slab (TES) concept to model the passive thermal capacity effect of profiled, composite metal floor decks. It is apparent from the modelling results that thermal mass is a highly complex phenomenon which is highly dependent upon building type, occupancy patterns, climate and many other aspects of the building design and servicing strategy. The ATM systems developed, both conceptually and for prototype testing, focussed on water-cooled composite slabs, the Cofradal floor system and the phase change material (PCM) Energain. In addition to laboratory testing of prototypes, whole building monitoring was undertaken at the Kubik building in Spain and the RWTH test building in Germany. Advanced thermal modelling was also undertaken to estimate the likely benefits of the ATM concept designs developed and for comparison with the test results. In addition to thermal testing, structural tests were conducted on composite floor specimens incorporating embedded water pipes. This Final Report presents the results of the activities carried out under this RFCS contract RFSR CT 2012 00033. The work carried out is reported in six major sections corresponding to the technical Work Packages of the project. Only summaries of the work carried out are provided in this report; all work undertaken is fully reported in the formal project deliverables.}, language = {en} } @incollection{SaldenFischerBarnat2016, author = {Salden, Peter and Fischer, Kathrin and Barnat, Miriam}, title = {Didaktische Studiengangentwicklung: Rahmenkonzepte und Praxisbeispiel}, series = {P{\"a}dagogische Hochschulentwicklung. Von der Programmierung zur Implementierung}, booktitle = {P{\"a}dagogische Hochschulentwicklung. Von der Programmierung zur Implementierung}, publisher = {Springer VS}, address = {Wiesbaden}, isbn = {978-3-658-12067-2}, doi = {10.1007/978-3-658-12067-2_9}, pages = {133 -- 149}, year = {2016}, abstract = {Die Studiengangentwicklung ist ein komplexer Prozess, in dem strukturelle Vorgaben beachtet, viele unterschiedliche Akteure/-innen einbezogen und nicht zuletzt angemessene didaktische L{\"o}sungen zum Erreichen der angestrebten Lernergebnisse gefunden werden m{\"u}ssen. Der vorliegende Text nimmt besonders den letzten Punkt in den Blick: Er zeigt, wie Studiengangentwicklung zu einem Thema der (Hochschul-)Didaktik geworden ist und wie sich der didaktische Ansatz von struktur- und prozessorientierten Ans{\"a}tzen unterscheidet, aber auch, wie er mit diesen zusammenh{\"a}ngt. An einem Beispiel aus dem Wirtschaftsingenieurwesen wird veranschaulicht, was didaktische Studiengangentwicklung in der Praxis ausmacht und wie eine konkrete Implementierung verlaufen kann. Auf dieser Grundlage wird abschließend ein erweitertes Modell der didaktischen Studiengangentwicklung vorgeschlagen.}, language = {de} } @article{RoeschKratzHeringetal.2016, author = {R{\"o}sch, C. and Kratz, F. and Hering, T. and Trautmann, S. and Umanskaya, N. and Tippk{\"o}tter, Nils and M{\"u}ller-Renno, C.M. and Ulber, Roland and Hannig, M. and Ziegler, C.}, title = {Albumin-lysozyme interactions: cooperative adsorption on titanium and enzymatic activity}, series = {Colloids and Surfaces B: Biointerfaces}, volume = {149}, journal = {Colloids and Surfaces B: Biointerfaces}, number = {1}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.colsurfb.2016.09.048}, pages = {115 -- 121}, year = {2016}, abstract = {The interplay of albumin (BSA) and lysozyme (LYZ) adsorbed simultaneously on titanium was analyzed by gel electrophoresis and BCA assay. It was found that BSA and lysozyme adsorb cooperatively. Additionally, the isoelectric point of the respective protein influences the adsorption. Also, the enzymatic activity of lysozyme and amylase (AMY) in mixtures with BSA was considered with respect to a possible influence of protein-protein interaction on enzyme activity. Indeed, an increase of lysozyme activity in the presence of BSA could be observed. In contrast, BSA does not influence the activity of amylase.}, language = {en} }