@article{StaeudleSeynnesLapsetal.2022, author = {St{\"a}udle, Benjamin and Seynnes, Olivier and Laps, Guido and Br{\"u}ggemann, Gert-Peter and Albracht, Kirsten}, title = {Altered gastrocnemius contractile behavior in former achilles tendon rupture patients during walking}, series = {Frontiers in Physiology}, volume = {13}, journal = {Frontiers in Physiology}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-042X}, doi = {10.3389/fphys.2022.792576}, pages = {12 Seiten}, year = {2022}, abstract = {Achilles tendon rupture (ATR) remains associated with functional limitations years after injury. Architectural remodeling of the gastrocnemius medialis (GM) muscle is typically observed in the affected leg and may compensate force deficits caused by a longer tendon. Yet patients seem to retain functional limitations during—low-force—walking gait. To explore the potential limits imposed by the remodeled GM muscle-tendon unit (MTU) on walking gait, we examined the contractile behavior of muscle fascicles during the stance phase. In a cross-sectional design, we studied nine former patients (males; age: 45 ± 9 years; height: 180 ± 7 cm; weight: 83 ± 6 kg) with a history of complete unilateral ATR, approximately 4 years post-surgery. Using ultrasonography, GM tendon morphology, muscle architecture at rest, and fascicular behavior were assessed during walking at 1.5 m⋅s-1 on a treadmill. Walking patterns were recorded with a motion capture system. The unaffected leg served as control. Lower limbs kinematics were largely similar between legs during walking. Typical features of ATR-related MTU remodeling were observed during the stance sub-phases corresponding to series elastic element (SEE) lengthening (energy storage) and SEE shortening (energy release), with shorter GM fascicles (36 and 36\%, respectively) and greater pennation angles (8° and 12°, respectively). However, relative to the optimal fascicle length for force production, fascicles operated at comparable length in both legs. Similarly, when expressed relative to optimal fascicle length, fascicle contraction velocity was not different between sides, except at the time-point of peak series elastic element (SEE) length, where it was 39 ± 49\% lower in the affected leg. Concomitantly, fascicles rotation during contraction was greater in the affected leg during the whole stance-phase, and architectural gear ratios (AGR) was larger during SEE lengthening. Under the present testing conditions, former ATR patients had recovered a relatively symmetrical walking gait pattern. Differences in seen AGR seem to accommodate the profound changes in MTU architecture, limiting the required fascicle shortening velocity. Overall, the contractile behavior of the GM fascicles does not restrict length- or velocity-dependent force potentials during this locomotor task.}, language = {en} } @article{Maurischat2022, author = {Maurischat, Andreas}, title = {Algebraic independence of the Carlitz period and its hyperderivatives}, series = {Journal of Number Theory}, volume = {240}, journal = {Journal of Number Theory}, publisher = {Elsevier}, address = {Orlando, Fla.}, issn = {0022-314X}, doi = {10.1016/j.jnt.2022.01.006}, pages = {145 -- 162}, year = {2022}, language = {en} } @masterthesis{Wabner2022, type = {Bachelor Thesis}, author = {Wabner, Magnus}, title = {Aeroux}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {95 Seiten}, year = {2022}, abstract = {Aeroux ist eine Formstudie {\"u}ber die Gestalt einer Luftschiffgondel. Luftschiffe bzw. Zeppeline werden oft mit dem Ungl{\"u}ck der Hindenburg in Lakehurst in Verbindung gebracht. Aeroux versucht diese Assoziation zu {\"u}berwinden und Luftschiffe in der Gegenwart zu verankern. Durch die gezielte, psychologisch inspirierte Gestaltung soll Sicherheit und Ruhe vermittelt werden, sollen spezifische Assoziationen geweckt werden, die weg f{\"u}hren von Bildern vergangener Tage eines brennenden Luftschiffs, um so Zeppeline als klimafreundlichere Alternative zum Flugzeug wieder ins Spiel zu bringen. Aeroux ist ein hybrides Verkehrsmittel, dass in der Lage ist, sowohl G{\"u}ter als auch Personen in verschiedenen Szenarien zu transportieren. Zeppeline bauchen keine befestigten Landebahnen oder Pisten. Regionen, die {\"u}ber Straßen schwer zug{\"a}nglich sind, k{\"o}nnen so in den Warenhandel integriert werden. Gleichermaßen k{\"o}nnen aber auch Meschen in Regionen bef{\"o}rdert werden, die durch Straßen oder Landebahnen nicht oder unzureichend erschlossen sind. Dar{\"u}ber hinaus kann Aeroux ein Ansatz sein die Unvertr{\"a}glichkeit von Fliegen und Klimaschutz aufzul{\"o}sen. Nicht zuletzt liegt in der gem{\"a}chlichen Art der Bewegung ein besonderer Zauber. Reisen k{\"o}nnten einen neuen Charakter erhalten: durch die großen Fensterfronten und die geringe Flugh{\"o}he k{\"o}nnen Landschaften auf der Reise neu wahrgenommen werden, der Weg wird wieder Teil des Reisens. Die Arbeit ist in erster Linie eine Auseinandersetzung mit der Form. Wie wirkt Form, wie lassen sich Assoziationen wecken, lenken, leiten. Wie kann technischer Anspruch, gesellschaftliche Bedingung, {\"o}kologisches Bewusstsein und nicht zuletzt Genuss in einem Objekt resultieren. Digitale und analoge Fertigung spielen im Zuge der Arbeit ineinander. So entstand das Design der Gondel, nach ersten h{\"a}ndischen Skizzen, digital. Das Model der Gondel wurde aus diesen Daten 3D gedruckt und die Darstellung der Tragh{\"u}lle ebenfalls auf Grundlage dieser Daten gelasert. Aeroux m{\"o}chte Lust auf alternatives Sehen, Denken und Handeln machen. Es gilt viel zu bewegen.}, language = {de} } @article{MandekarHollandThielenetal.2022, author = {Mandekar, Swati and Holland, Abigail and Thielen, Moritz and Behbahani, Mehdi and Melnykowycz, Mark}, title = {Advancing towards Ubiquitous EEG, Correlation of In-Ear EEG with Forehead EEG}, series = {Sensors}, volume = {22}, journal = {Sensors}, number = {4}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s22041568}, pages = {1 -- 19}, year = {2022}, abstract = {Wearable EEG has gained popularity in recent years driven by promising uses outside of clinics and research. The ubiquitous application of continuous EEG requires unobtrusive form-factors that are easily acceptable by the end-users. In this progression, wearable EEG systems have been moving from full scalp to forehead and recently to the ear. The aim of this study is to demonstrate that emerging ear-EEG provides similar impedance and signal properties as established forehead EEG. EEG data using eyes-open and closed alpha paradigm were acquired from ten healthy subjects using generic earpieces fitted with three custom-made electrodes and a forehead electrode (at Fpx) after impedance analysis. Inter-subject variability in in-ear electrode impedance ranged from 20 kΩ to 25 kΩ at 10 Hz. Signal quality was comparable with an SNR of 6 for in-ear and 8 for forehead electrodes. Alpha attenuation was significant during the eyes-open condition in all in-ear electrodes, and it followed the structure of power spectral density plots of forehead electrodes, with the Pearson correlation coefficient of 0.92 between in-ear locations ELE (Left Ear Superior) and ERE (Right Ear Superior) and forehead locations, Fp1 and Fp2, respectively. The results indicate that in-ear EEG is an unobtrusive alternative in terms of impedance, signal properties and information content to established forehead EEG.}, language = {en} } @article{ZhantlessovaSavitskayaKistaubayevaetal.2022, author = {Zhantlessova, Sirina and Savitskaya, Irina and Kistaubayeva, Aida and Ignatova, Ludmila and Talipova, Aizhan and Pogrebnjak, Alexander and Digel, Ilya}, title = {Advanced "Green" prebiotic composite of bacterial cellulose/pullulan based on synthetic biology-powered microbial coculture strategy}, series = {Polymers}, volume = {14}, journal = {Polymers}, number = {15}, publisher = {MDPI}, address = {Basel}, issn = {2073-4360}, doi = {10.3390/polym14153224}, pages = {Artikel 3224}, year = {2022}, abstract = {Bacterial cellulose (BC) is a biopolymer produced by different microorganisms, but in biotechnological practice, Komagataeibacter xylinus is used. The micro- and nanofibrillar structure of BC, which forms many different-sized pores, creates prerequisites for the introduction of other polymers into it, including those synthesized by other microorganisms. The study aims to develop a cocultivation system of BC and prebiotic producers to obtain BC-based composite material with prebiotic activity. In this study, pullulan (PUL) was found to stimulate the growth of the probiotic strain Lactobacillus rhamnosus GG better than the other microbial polysaccharides gellan and xanthan. BC/PUL biocomposite with prebiotic properties was obtained by cocultivation of Komagataeibacter xylinus and Aureobasidium pullulans, BC and PUL producers respectively, on molasses medium. The inclusion of PUL in BC is proved gravimetrically by scanning electron microscopy and by Fourier transformed infrared spectroscopy. Cocultivation demonstrated a composite effect on the aggregation and binding of BC fibers, which led to a significant improvement in mechanical properties. The developed approach for "grafting" of prebiotic activity on BC allows preparation of environmentally friendly composites of better quality.}, language = {en} } @article{SchwagerFleschSchwarzboezletal.2022, author = {Schwager, Christian and Flesch, Robert and Schwarzb{\"o}zl, Peter and Herrmann, Ulf and Teixeira Boura, Cristiano Jos{\´e}}, title = {Advanced two phase flow model for transient molten salt receiver system simulation}, series = {Solar Energy}, volume = {232}, journal = {Solar Energy}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0038-092X (print)}, doi = {10.1016/j.solener.2021.12.065}, pages = {362 -- 375}, year = {2022}, abstract = {In order to realistically predict and optimize the actual performance of a concentrating solar power (CSP) plant sophisticated simulation models and methods are required. This paper presents a detailed dynamic simulation model for a Molten Salt Solar Tower (MST) system, which is capable of simulating transient operation including detailed startup and shutdown procedures including drainage and refill. For appropriate representation of the transient behavior of the receiver as well as replication of local bulk and surface temperatures a discretized receiver model based on a novel homogeneous two-phase (2P) flow modelling approach is implemented in Modelica Dymola®. This allows for reasonable representation of the very different hydraulic and thermal properties of molten salt versus air as well as the transition between both. This dynamic 2P receiver model is embedded in a comprehensive one-dimensional model of a commercial scale MST system and coupled with a transient receiver flux density distribution from raytracing based heliostat field simulation. This enables for detailed process prediction with reasonable computational effort, while providing data such as local salt film and wall temperatures, realistic control behavior as well as net performance of the overall system. Besides a model description, this paper presents some results of a validation as well as the simulation of a complete startup procedure. Finally, a study on numerical simulation performance and grid dependencies is presented and discussed.}, language = {en} } @article{KaulenSchwabedalSchneideretal.2022, author = {Kaulen, Lars and Schwabedal, Justus T. C. and Schneider, Jules and Ritter, Philipp and Bialonski, Stephan}, title = {Advanced sleep spindle identification with neural networks}, series = {Scientific Reports}, volume = {12}, journal = {Scientific Reports}, number = {Article number: 7686}, publisher = {Springer Nature}, address = {London}, issn = {2045-2322}, doi = {10.1038/s41598-022-11210-y}, pages = {1 -- 10}, year = {2022}, abstract = {Sleep spindles are neurophysiological phenomena that appear to be linked to memory formation and other functions of the central nervous system, and that can be observed in electroencephalographic recordings (EEG) during sleep. Manually identified spindle annotations in EEG recordings suffer from substantial intra- and inter-rater variability, even if raters have been highly trained, which reduces the reliability of spindle measures as a research and diagnostic tool. The Massive Online Data Annotation (MODA) project has recently addressed this problem by forming a consensus from multiple such rating experts, thus providing a corpus of spindle annotations of enhanced quality. Based on this dataset, we present a U-Net-type deep neural network model to automatically detect sleep spindles. Our model's performance exceeds that of the state-of-the-art detector and of most experts in the MODA dataset. We observed improved detection accuracy in subjects of all ages, including older individuals whose spindles are particularly challenging to detect reliably. Our results underline the potential of automated methods to do repetitive cumbersome tasks with super-human performance.}, language = {en} } @masterthesis{Sehl2022, type = {Bachelor Thesis}, author = {Sehl, Kristina}, title = {Adapt or die : Heimische W{\"a}lder im Wandel durch Mensch und Zeit}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {316 Seiten}, year = {2022}, abstract = {Wo einst fast l{\"u}ckenlos Laubw{\"a}lder wuchsen, steht heute nur noch ein Drittel der urspr{\"u}nglichen Waldfl{\"a}che. Echte Urw{\"a}lder gibt es hier schon lange nicht mehr: Die Rede ist vom deutschen Wald. Unsere Welt ist im Wandel. Auch in unseren heimischen W{\"a}ldern lassen sich die Einfl{\"u}sse von Mensch und Klimawandel auf die Biodiversit{\"a}t beobachten. Die illustrierte Publikation „Adapt or die" l{\"a}dt mit mehr als 80 großformatigen Artenportraits, Habitat-Kartierungen und gestalteten Themenklappenseiten zur Auseinandersetzung mit dem Wandel unserer heimischen W{\"a}lder ein. Dabei sensibilisiert sie f{\"u}r einen bewussteren Umgang mit Umwelt und Natur. Erweiterungen durch Augmented Reality bieten vereinzelt neben dem Printprodukt aktualisierbare Prognosen, digital und ressourcenschonend. Das komplexe {\"O}kosystem des Waldes reagiert empfindlich auf Ver{\"a}nderungen: Wer sich nicht anpassen kann, wird verschwinden.}, language = {de} } @masterthesis{Guth2022, type = {Bachelor Thesis}, author = {Guth, Katharina}, title = {aco : eine digitale Anwendung zur Verbesserung der Lebensqualit{\"a}t von Neurodermitis-Patient:innen}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {267 Seiten}, year = {2022}, abstract = {Neurodermitis hat in den letzten Jahrzehnten deutlich zugenommen. Etwa 10 bis 15 Prozent der Kinder und 2,5 bis 3,5 Prozent der Erwachsenen sind davon betroffen. F{\"u}r sie stellen Auswirkungen der Hautkrankheit auf K{\"o}rper und Psyche eine enorme Einschr{\"a}nkung der Lebensqualit{\"a}t dar. Die App „aco" m{\"o}chte Neurodermitis-Patient:Innen dabei unterst{\"u}tzen, ihre Behandlung selbst in die Hand zu nehmen. Eine ganzheitliche Therapie umfasst eben nicht nur Fachpersonen, sondern auch Patient:Innen selbst. Durch eine regelm{\"a}ßige Dokumentation erm{\"o}glicht die Anwendung eine aktive Auseinandersetzung mit der Krankheit. Triggerfaktoren werden ausgewertet und es wird Wissen {\"u}ber Behandlungsm{\"o}glichkeiten vermittelt. Zudem wird ein Austausch erm{\"o}glicht, der emotionale und praktische Unterst{\"u}tzung bieten soll. Damit m{\"o}chte „aco" Betroffenen eine M{\"o}glichkeit geben, das Ruder selbst in die Hand zu nehmen und leistet damit einen wichtigen Beitrag zur Therapie von Neurodermitis.}, language = {de} } @techreport{SiegertBongaertsWagneretal.2022, author = {Siegert, Petra and Bongaerts, Johannes and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Selmer, Thorsten}, title = {Abschlussbericht zum Projekt zur {\"U}berwachung biotechnologischer Prozesse mittels Diacetyl-/Acetoin-Biosensor und Evaluierung von Acetoin-Reduktasen zur Verwendung in Biotransformationen}, address = {Aachen}, organization = {FH Aachen}, pages = {16 Seiten}, year = {2022}, language = {de} }