@article{BertzMolinnusSchoeningetal.2023, author = {Bertz, Morten and Molinnus, Denise and Sch{\"o}ning, Michael Josef and Homma, Takayuki}, title = {Real-time monitoring of H₂O₂ sterilization on individual bacillus atrophaeus spores by optical sensing with trapping Raman spectroscopy}, series = {Chemosensors}, volume = {8}, journal = {Chemosensors}, number = {11}, publisher = {MDPI}, address = {Basel}, issn = {2227-9040}, doi = {10.3390/chemosensors11080445}, pages = {Artikel 445}, year = {2023}, abstract = {Hydrogen peroxide (H₂O₂), a strong oxidizer, is a commonly used sterilization agent employed during aseptic food processing and medical applications. To assess the sterilization efficiency with H₂O₂, bacterial spores are common microbial systems due to their remarkable robustness against a wide variety of decontamination strategies. Despite their widespread use, there is, however, only little information about the detailed time-resolved mechanism underlying the oxidative spore death by H₂O₂. In this work, we investigate chemical and morphological changes of individual Bacillus atrophaeus spores undergoing oxidative damage using optical sensing with trapping Raman microscopy in real-time. The time-resolved experiments reveal that spore death involves two distinct phases: (i) an initial phase dominated by the fast release of dipicolinic acid (DPA), a major spore biomarker, which indicates the rupture of the spore's core; and (ii) the oxidation of the remaining spore material resulting in the subsequent fragmentation of the spores' coat. Simultaneous observation of the spore morphology by optical microscopy corroborates these mechanisms. The dependence of the onset of DPA release and the time constant of spore fragmentation on H₂O₂ shows that the formation of reactive oxygen species from H₂O₂ is the rate-limiting factor of oxidative spore death.}, language = {en} } @article{WendlandtKochBritzetal.2023, author = {Wendlandt, Tim and Koch, Claudia and Britz, Beate and Liedek, Anke and Schmidt, Nora and Werner, Stefan and Gleba, Yuri and Vahidpour, Farnoosh and Welden, Melanie and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Facile Purification and Use of Tobamoviral Nanocarriers for Antibody-Mediated Display of a Two-Enzyme System}, series = {Viruses}, volume = {9}, journal = {Viruses}, number = {15}, publisher = {MDPI}, address = {Basel}, issn = {1999-4915}, doi = {doi.org/10.3390/v15091951}, pages = {Artikel 1951}, year = {2023}, abstract = {Immunosorbent turnip vein clearing virus (TVCV) particles displaying the IgG-binding domains D and E of Staphylococcus aureus protein A (PA) on every coat protein (CP) subunit (TVCVPA) were purified from plants via optimized and new protocols. The latter used polyethylene glycol (PEG) raw precipitates, from which virions were selectively re-solubilized in reverse PEG concentration gradients. This procedure improved the integrity of both TVCVPA and the wild-type subgroup 3 tobamovirus. TVCVPA could be loaded with more than 500 IgGs per virion, which mediated the immunocapture of fluorescent dyes, GFP, and active enzymes. Bi-enzyme ensembles of cooperating glucose oxidase and horseradish peroxidase were tethered together on the TVCVPA carriers via a single antibody type, with one enzyme conjugated chemically to its Fc region, and the other one bound as a target, yielding synthetic multi-enzyme complexes. In microtiter plates, the TVCVPA-displayed sugar-sensing system possessed a considerably increased reusability upon repeated testing, compared to the IgG-bound enzyme pair in the absence of the virus. A high coverage of the viral adapters was also achieved on Ta2O5 sensor chip surfaces coated with a polyelectrolyte interlayer, as a prerequisite for durable TVCVPA-assisted electrochemical biosensing via modularly IgG-assembled sensor enzymes.}, language = {en} } @misc{SteuerDankertBergPostweilerLeichtScholten2023, author = {Steuer-Dankert, Linda and Berg-Postweiler, Julia and Leicht-Scholten, Carmen}, title = {One does not fit all: applying anti-bias trainings in academia}, series = {Twenty-third international conference on diversity in organizations, communities \& nations June 22 - 23, 2023 Toronto Metropolitan University, Rogers Communication Centre Toronto, Canada}, journal = {Twenty-third international conference on diversity in organizations, communities \& nations June 22 - 23, 2023 Toronto Metropolitan University, Rogers Communication Centre Toronto, Canada}, year = {2023}, abstract = {Anti-bias trainings are increasingly demanded and practiced in academia and industry to increase employees' sensitivity to discrimination, racism, and diversity. Under the heading of "Diversity Management", anti-bias trainings are mainly offered as one-off workshops intending to raise awareness of unconscious biases, create a diversity-affirming corporate culture, awake awareness of the potential of diversity, and ultimately enable the reflection of diversity in development processes. However, coming from childhood education, research and scientific articles on the sustainable effectiveness of anti-bias in adulthood, especially in academia, are very scarce. In order to fill this research gap, the paper explores how sustainable the effects of individual anti-bias trainings on the behavior of participants are. In order to investigate this, participant observation in a qualitative pre-post setting was conducted, analyzing anti-bias trainings in an academic context. Two observers actively participated in the training sessions and documented the activities and reflection processes of the participants. Overall, the results question the effectiveness of single anti-bias trainings and show that a target-group adaptive approach is mandatory due to the background of the approach in early childhood education. Therefore, it can be concluded that anti-bias work needs to be adapted to the target group's needs and reality of life. Furthermore, the study reveals that single anti-bias trainings must be embedded in a holistic diversity management approach to stimulate sustainable reflection processes among the target group. This paper is one of the first to scientifically evaluate anti-bias training effectiveness, especially in engineering sciences and the university context.}, language = {en} } @incollection{EggertZaehlWolfetal.2023, author = {Eggert, Mathias and Z{\"a}hl, Philipp M. and Wolf, Martin R. and Haase, Martin}, title = {Applying leaderboards for quality improvement in software development projects}, series = {Software Engineering for Games in Serious Contexts}, booktitle = {Software Engineering for Games in Serious Contexts}, editor = {Cooper, Kendra M.L. and Bucchiarone, Antonio}, publisher = {Springer}, address = {Cham}, isbn = {978-3-031-33337-8 (Print)}, doi = {10.1007/978-3-031-33338-5_11}, pages = {243 -- 263}, year = {2023}, abstract = {Software development projects often fail because of insufficient code quality. It is now well documented that the task of testing software, for example, is perceived as uninteresting and rather boring, leading to poor software quality and major challenges to software development companies. One promising approach to increase the motivation for considering software quality is the use of gamification. Initial research works already investigated the effects of gamification on software developers and come to promising. Nevertheless, a lack of results from field experiments exists, which motivates the chapter at hand. By conducting a gamification experiment with five student software projects and by interviewing the project members, the chapter provides insights into the changing programming behavior of information systems students when confronted with a leaderboard. The results reveal a motivational effect as well as a reduction of code smells.}, language = {en} } @masterthesis{Scheffel2023, type = {Bachelor Thesis}, author = {Scheffel, Zeno Samuel}, title = {Identit{\"a}t, Zusammenhalt, Zugeh{\"o}rigkeit : Die Exploration der Gestaltung von Fußballtrikots}, publisher = {FH Aachen}, address = {Aachen}, pages = {95 Seiten}, year = {2023}, abstract = {Das Fußballtrikot - Arbeitsbekleidung, Identifikationsmerkmal, Distinktionsmerkmal? Was ist das Fußballtrikot, was sind seine identit{\"a}tsstiftenden Merkmale und welche Gestaltungsparameter pr{\"a}gen sein heutiges Aussehen? In dieser Publikation wird die Geschichte des Trikots ebenso wie die {\"a}ußeren Einfl{\"u}sse auf sein heutiges Erscheinungsbild dokumentiert und analysiert. Die Publikation definiert die verschiedenen Gestaltungsparameter, erl{\"a}utert diese und ordnet sie ein. Ebenso wird ein Einblick in den kreativen Gestaltungsprozess von Fußballtrikots gew{\"a}hrt. Das Ziel dieser Publikation besteht darin, das Erscheinungsbild von Trikots zu verstehen und eine kritische Reflexion dar{\"u}ber zu erm{\"o}glichen, wie das Fußballtrikot individuell definiert wird.}, language = {de} } @masterthesis{Schlepuetz2023, type = {Bachelor Thesis}, author = {Schlep{\"u}tz, Nico}, title = {News Flow : Nachrichten- und Informationsprozesse im digitalen Wandel}, publisher = {FH Aachen}, address = {Aachen}, pages = {89 Seiten}, year = {2023}, abstract = {"News Flow" Nachrichten- und Informationsprozesse im digitalen Wandel. In der digitalen Welt sind wir von Informationen aus unterschiedlichen Medien umgeben. Die st{\"a}ndige Verf{\"u}gbarkeit f{\"u}hrt zu {\"U}berforderung und Orientierungslosigkeit. Junge Menschen bevorzugen Streaming und Social Media gegen{\"u}ber traditionellen Nachrichten. Angesichts globaler Krisen und Desinformation sind innovative L{\"o}sungen wichtig, um den Informationsfluss zu verbessern. "News Flow" ist eine digitale Anwendung f{\"u}r Alternativen des Nachrichtenkonsums. Sie ber{\"u}cksichtigt individuelle Bed{\"u}rfnisse und nutzt moderne Technologien. Durch die visuelle Vermittlung wird das Interesse an Nachrichten gesteigert und junge Zielgruppen angesprochen. Diese Arbeit stellt sich den Herausforderungen des digitalen Wandels im Nachrichtenbereich und er{\"o}ffnet eine neue Perspektive auf den Nachrichtenkonsum.}, language = {de} } @masterthesis{Schmidt2023, type = {Bachelor Thesis}, author = {Schmidt, Lucie}, title = {„Keine Schmerzen in der Regel" : Aufkl{\"a}rungskampagne zur Fr{\"u}herkennung der Krankheit Endometriose}, publisher = {FH Aachen}, address = {Aachen}, pages = {75 Seiten}, year = {2023}, abstract = {Jede zehnte Frau hat Endometriose. Hierbei entstehen Zysten und Entz{\"u}ndungen, welche sich beispielsweise an den Eierst{\"o}cken ansiedeln k{\"o}nnen. Wie kann es also sein, dass so viele noch nie was von dieser Erkrankung geh{\"o}rt haben? Mit der online Aufkl{\"a}rungskampagne „ Keine Schmerzen in der Regel" soll sich das {\"a}ndern. In vielen F{\"a}llen werden Beschwerden der Endometriose f{\"a}lschlicherweise als normale Menstruationsbeschwerden abgetan. Die Differenzierung zwischen normal und nicht normal misslingt. Die Aufmerksamkeit von M{\"a}dchen und Frauen, die sich in den nicht normalen Aspekten wiederfinden, soll erregt werden. Daf{\"u}r werden vier Symptome visualisiert und gegen{\"u}bergestellt. Zus{\"a}tzlich bietet ein Schnellcheck weitere Informationen. Diese Kampagne soll dem Problem der Unbekanntheit von Endometriose entgegenwirken und ein gesellschaftliches Bewusstsein f{\"u}r sie schaffen.}, language = {de} } @book{Heuermann2023, author = {Heuermann, Holger}, title = {Mikrowellentechnik : Feldsimulation, nichtlineare Schaltungstechnik, Komponenten und Subsysteme, Plasmatechnik, Antennen und Ausbreitung}, edition = {2. Auflage}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-41286-9}, doi = {10.1007/978-3-658-41287-6}, pages = {XVI, 394 Seiten}, year = {2023}, abstract = {Das Lehrbuch behandelt alle Aspekte, die den aktuellen Stand der GHz-Technik betreffen. Das Buch behandelt die verschiedenen numerischen Feldsimulationsverfahren. Mit vielen modernen Themen.}, language = {de} } @inproceedings{EichenbaumNikolovskiMuelhensetal.2023, author = {Eichenbaum, Julian and Nikolovski, Gjorgji and M{\"u}lhens, Leon and Reke, Michael and Ferrein, Alexander and Scholl, Ingrid}, title = {Towards a lifelong mapping approach using Lanelet 2 for autonomous open-pit mine operations}, series = {2023 IEEE 19th International Conference on Automation Science and Engineering (CASE)}, booktitle = {2023 IEEE 19th International Conference on Automation Science and Engineering (CASE)}, publisher = {IEEE}, isbn = {979-8-3503-2069-5 (Online)}, doi = {10.1109/CASE56687.2023.10260526}, pages = {8 Seiten}, year = {2023}, abstract = {Autonomous agents require rich environment models for fulfilling their missions. High-definition maps are a well-established map format which allows for representing semantic information besides the usual geometric information of the environment. These are, for instance, road shapes, road markings, traffic signs or barriers. The geometric resolution of HD maps can be as precise as of centimetre level. In this paper, we report on our approach of using HD maps as a map representation for autonomous load-haul-dump vehicles in open-pit mining operations. As the mine undergoes constant change, we also need to constantly update the map. Therefore, we follow a lifelong mapping approach for updating the HD maps based on camera-based object detection and GPS data. We show our mapping algorithm based on the Lanelet 2 map format and show our integration with the navigation stack of the Robot Operating System. We present experimental results on our lifelong mapping approach from a real open-pit mine.}, language = {en} } @inproceedings{TischbeinKeanVertgewalletal.2023, author = {Tischbein, Franziska and Kean, Kilian and Vertgewall, Chris Martin and Ulbig, Andreas and Altherr, Lena}, title = {Determination of the topology of low-voltage distribution grids using cluster methods}, series = {27th International Conference on Electricity Distribution (CIRED 2023)}, booktitle = {27th International Conference on Electricity Distribution (CIRED 2023)}, publisher = {IEEE}, isbn = {978-1-83953-855-1}, doi = {10.1049/icp.2023.0478}, pages = {1 -- 5}, year = {2023}, abstract = {Due to the decarbonization of the energy sector, the electric distribution grids are undergoing a major transformation, which is expected to increase the load on the operating resources due to new electrical loads and distributed energy resources. Therefore, grid operators need to gradually move to active grid management in order to ensure safe and reliable grid operation. However, this requires knowledge of key grid variables, such as node voltages, which is why the mass integration of measurement technology (smart meters) is necessary. Another problem is the fact that a large part of the topology of the distribution grids is not sufficiently digitized and models are partly faulty, which means that active grid operation management today has to be carried out largely blindly. It is therefore part of current research to develop methods for determining unknown grid topologies based on measurement data. In this paper, different clustering algorithms are presented and their performance of topology detection of low voltage grids is compared. Furthermore, the influence of measurement uncertainties is investigated in the form of a sensitivity analysis.}, language = {en} }