@inproceedings{MohanGrossMenzeletal.2021,
  author    = {Mohan, Nijanthan and Groß, Rolf Fritz and Menzel, Karsten and Theis, Fabian},
  title     = {Opportunities and Challenges in the Implementation of Building Information Modeling for Prefabrication of Heating, Ventilation and Air Conditioning Systems in Small and Medium-Sized Contracting Companies in Germany - A Case Study},
  series = {WIT Transactions on The Built Environment, Vol. 205},
  booktitle = {WIT Transactions on The Built Environment, Vol. 205},
  publisher = {WIT Press},
  address   = {Southampton},
  issn      = {1743-3509},
  doi       = {10.2495/BIM210101},
  pages     = {117 -- 126},
  year      = {2021},
  abstract  = {Even though BIM (Building Information Modelling) is successfully implemented in most of the world, it is still in the early stages in Germany, since the stakeholders are sceptical of its reliability and efficiency. The purpose of this paper is to analyse the opportunities and obstacles to implementing BIM for prefabrication. Among all other advantages of BIM, prefabrication is chosen for this paper because it plays a vital role in creating an impact on the time and cost factors of a construction project. The project stakeholders and participants can explicitly observe the positive impact of prefabrication, which enables the breakthrough of the scepticism factor among the small-scale construction companies. The analysis consists of the development of a process workflow for implementing prefabrication in building construction followed by a practical approach, which was executed with two case studies. It was planned in such a way that, the first case study gives a first-hand experience for the workers at the site on the BIM model so that they can make much use of the created BIM model, which is a better representation compared to the traditional 2D plan. The main aim of the first case study is to create a belief in the implementation of BIM Models, which was succeeded by the execution of offshore prefabrication in the second case study. Based on the case studies, the time analysis was made and it is inferred that the implementation of BIM for prefabrication can reduce construction time, ensures minimal wastes, better accuracy, less problem-solving at the construction site. It was observed that this process requires more planning time, better communication between different disciplines, which was the major obstacle for successful implementation. This paper was carried out from the perspective of small and medium-sized mechanical contracting companies for the private building sector in Germany.},
  language  = {en}
}
@article{BurgerRumpfDoetal.2021,
  author    = {Burger, Ren{\´e} and Rumpf, Jessica and Do, Xuan Tung and Monakhova, Yulia and Diehl, Bernd W. K. and Rehahn, Matthias and Schulze, Margit},
  title     = {Is NMR combined with multivariate regression applicable for the molecular weight determination of randomly cross-linked polymers such as lignin?},
  series = {ACS Omega},
  volume    = {6},
  journal   = {ACS Omega},
  number    = {44},
  publisher = {ACS Publications},
  address   = {Washington, DC},
  issn      = {2470-1343},
  doi       = {10.1021/acsomega.1c03574},
  pages     = {29516 -- 29524},
  year      = {2021},
  abstract  = {The molecular weight properties of lignins are one of the key elements that need to be analyzed for a successful industrial application of these promising biopolymers. In this study, the use of 1H NMR as well as diffusion-ordered spectroscopy (DOSY NMR), combined with multivariate regression methods, was investigated for the determination of the molecular weight (Mw and Mn) and the polydispersity of organosolv lignins (n = 53, Miscanthus x giganteus, Paulownia tomentosa, and Silphium perfoliatum). The suitability of the models was demonstrated by cross validation (CV) as well as by an independent validation set of samples from different biomass origins (beech wood and wheat straw). CV errors of ca. 7-9 and 14-16\% were achieved for all parameters with the models from the 1H NMR spectra and the DOSY NMR data, respectively. The prediction errors for the validation samples were in a similar range for the partial least squares model from the 1H NMR data and for a multiple linear regression using the DOSY NMR data. The results indicate the usefulness of NMR measurements combined with multivariate regression methods as a potential alternative to more time-consuming methods such as gel permeation chromatography.},
  language  = {en}
}
@article{MonakhovaDiehl2021,
  author    = {Monakhova, Yulia and Diehl, Bernd W. K.},
  title     = {Simplification of NMR Workflows by Standardization Using 2H Integral of Deuterated Solvent as Applied to Aloe vera Preparations},
  series = {Applied Magnetic Resonance},
  volume    = {52},
  journal   = {Applied Magnetic Resonance},
  number    = {11},
  publisher = {Springer},
  address   = {Cham},
  issn      = {1613-7507},
  doi       = {10.1007/s00723-021-01393-4},
  pages     = {1591 -- 1600},
  year      = {2021},
  abstract  = {In this study, a recently proposed NMR standardization approach by 2H integral of deuterated solvent for quantitative multicomponent analysis of complex mixtures is presented. As a proof of principle, the existing NMR routine for the analysis of Aloe vera products was modified. Instead of using absolute integrals of targeted compounds and internal standard (nicotinamide) from 1H-NMR spectra, quantification was performed based on the ratio of a particular 1H-NMR compound integral and 2H-NMR signal of deuterated solvent D2O. Validation characteristics (linearity, repeatability, accuracy) were evaluated and the results showed that the method has the same precision as internal standardization in case of multicomponent screening. Moreover, a dehydration process by freeze drying is not necessary for the new routine. Now, our NMR profiling of A. vera products needs only limited sample preparation and data processing. The new standardization methodology provides an appealing alternative for multicomponent NMR screening. In general, this novel approach, using standardization by 2H integral, benefits from reduced sample preparation steps and uncertainties, and is recommended in different application areas (purity determination, forensics, pharmaceutical analysis, etc.).},
  language  = {en}
}
@article{PourshahidiAchtsnichtNambipareecheeetal.2021,
  author    = {Pourshahidi, Ali Mohammad and Achtsnicht, Stefan and Nambipareechee, Mrinal Murali and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim},
  title     = {Multiplex detection of magnetic beads using offset field dependent frequency mixing magnetic detection},
  series = {Sensors},
  volume    = {21},
  journal   = {Sensors},
  number    = {17},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s21175859},
  pages     = {16 Seiten},
  year      = {2021},
  abstract  = {Magnetic immunoassays employing Frequency Mixing Magnetic Detection (FMMD) have recently become increasingly popular for quantitative detection of various analytes. Simultaneous analysis of a sample for two or more targets is desirable in order to reduce the sample amount, save consumables, and save time. We show that different types of magnetic beads can be distinguished according to their frequency mixing response to a two-frequency magnetic excitation at different static magnetic offset fields. We recorded the offset field dependent FMMD response of two different particle types at frequencies ƒ₁ + n⋅ƒ₂, n = 1, 2, 3, 4 with ƒ₁ = 30.8 kHz and ƒ₂ = 63 Hz. Their signals were clearly distinguishable by the locations of the extremes and zeros of their responses. Binary mixtures of the two particle types were prepared with different mixing ratios. The mixture samples were analyzed by determining the best linear combination of the two pure constituents that best resembled the measured signals of the mixtures. Using a quadratic programming algorithm, the mixing ratios could be determined with an accuracy of greater than 14\%. If each particle type is functionalized with a different antibody, multiplex detection of two different analytes becomes feasible.},
  language  = {en}
}
@article{BurmistrovaSobolevaMonakhova2021,
  author    = {Burmistrova, Natalia A. and Soboleva, Polina M. and Monakhova, Yulia},
  title     = {Is infrared spectroscopy combined with multivariate analysis a promising tool for heparin authentication?},
  series = {Journal of Pharmaceutical and Biomedical Analysis},
  volume    = {194},
  journal   = {Journal of Pharmaceutical and Biomedical Analysis},
  number    = {Article number: 113811},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {0731-7085},
  doi       = {10.1016/j.jpba.2020.113811},
  year      = {2021},
  abstract  = {The investigation of the possibility to determine various characteristics of powder heparin (n = 115) was carried out with infrared spectroscopy. The evaluation of heparin samples included several parameters such as purity grade, distributing company, animal source as well as heparin species (i.e. Na-heparin, Ca-heparin, and heparinoids). Multivariate analysis using principal component analysis (PCA), soft independent modelling of class analogy (SIMCA), and partial least squares - discriminant analysis (PLS-DA) were applied for the modelling of spectral data. Different pre-processing methods were applied to IR spectral data; multiplicative scatter correction (MSC) was chosen as the most relevant. Obtained results were confirmed by nuclear magnetic resonance (NMR) spectroscopy. Good predictive ability of this approach demonstrates the potential of IR spectroscopy and chemometrics for screening of heparin quality. This approach, however, is designed as a screening tool and is not considered as a replacement for either of the methods required by USP and FDA.},
  language  = {en}
}
@masterthesis{Paulzen2021,
  type      = {Bachelor Thesis},
  author    = {Paulzen, Lena},
  title     = {Nachhaltiges Corporate Packaging Design: Am Beispiel von Naturkosmetik Produkten.},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {124 Seiten},
  year      = {2021},
  abstract  = {Diese Bachelorarbeit widmet sich dem nachhaltigen Packaging-Design von Kosmetikprodukten. Dies wird am Beispiel eines Naturkosmetik-Unternehmens dargestellt. Die Gestaltung einer Shampoo-Flasche wird in dem vorliegenden Projekt exemplarisch f{\"u}r die thematische und gestalterische Untersuchung genutzt. Zudem wurden mit Tube und Tiegel noch zwei weitere Verpackungsformen erstellt. Das Ziel dieser Arbeit ist es, eine nachhaltige Verpackung zu gestalten. Diese soll den hohen CO2-Ausstoß bei der Herstellung von Verpackungen verringern und dabei dem Anspruch des Marketings gerecht werden. Hierbei wurde ein Logo-Design, ein Farbkonzept, eine einheitliche Formsprache und eine Typografie erarbeitet.},
  language  = {de}
}
@masterthesis{Wahlefeld2021,
  type      = {Bachelor Thesis},
  author    = {Wahlefeld, Leon},
  title     = {Generative Gestaltung: wie eine Herangehensweise die Zukunft des Designs revolutionieren k{\"o}nnte.},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {188 Seiten},
  year      = {2021},
  abstract  = {Diese Bachelorarbeit setzt sich mit der „Generativen Gestaltung" und ihren M{\"o}glichkeiten f{\"u}r Gestaltende auseinander. Die automatisierte Bearbeitung eines gestalterischen Projektes soll vorrangig Vorteile beim Arbeiten mit großen Datenmengen bieten. Ziel war es, eine Plakatreihe zu entwerfen, die auf der Grundlage eines Codes - also eines strikten Regelwerks - basiert. Mithilfe dieses Verfahrens kann auf Knopfdruck eine beliebige Menge an Plakaten generiert werden. Durch die Festlegung bestimmter Parameter innerhalb des Codes wird gew{\"a}hrleistet, dass jedes ausgespielte Plakat anders ist als sein Vorg{\"a}nger. Diese Arbeit dient als eine erste anskizzierte Grundlage daf{\"u}r, wie grafischer Output automatisiert und vor allem aktualisiert generiert werden kann. Dieses Prinzip kann auf eine Vielzahl von Inhalten und Umsetzungen angewendet werden.},
  language  = {de}
}
@masterthesis{Schmitz2021,
  type      = {Bachelor Thesis},
  author    = {Schmitz, Jennifer},
  title     = {Inklusives Design: Multisensorisches Branding f{\"u}r sehbehinderte, blinde und sehende Menschen},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {77 Seiten},
  year      = {2021},
  abstract  = {Multisensorisches Branding bezeichnet die Gestaltung f{\"u}r mindestens zwei Sinne. Diese Bachelorarbeit beinhaltet daher ein Konzept, um sehbehinderten Menschen und Blinden das Branding einer Marke im Bereich der Bekleidungsindustrie zug{\"a}nglich zu machen. Durch die gezielte Kombination von Haptik und Optik ist im Rahmen dieser Arbeit eine Bekleidungsmarke entstanden, deren Textilien jegliche Informationen f{\"u}r sehbehinderte und blinde Menschen enthalten, ohne dabei auf eine ansprechende Optik f{\"u}r Sehende zu verzichten. Vor allem durch neu entwickelte Open Source Symbole, die f{\"u}hlbar sind, und einen Barcode wird Betroffenen in Zukunft der Kauf von Bekleidung sowie der Waschvorgang erleichtert.},
  language  = {de}
}
@masterthesis{BaesslerKleinkunen2021,
  type      = {Bachelor Thesis},
  author    = {Baeßler, Franziska and Kleinkunen, Tristan},
  title     = {MOBI: zukunftsorientiertes modulares Baukastensystem f{\"u}r Bibliotheken},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {209 Seiten},
  year      = {2021},
  abstract  = {Das Ziel des Bibliothekskonzeptes ist es, Hybridbibliotheken als Symbiose aus zukunftsweisender Medientechnologie und klassischer Funktionalit{\"a}t in Modulbauweise in Bestandsarchitektur zu integrieren. Der L{\"o}sungsansatz liegt in einer kosteng{\"u}nstigen dynamischen Modularit{\"a}t, welche als Plug-In, Add-On, Single oder Mobilkonzept nutzbar ist. Das modulare System setzt hierbei auf Grundmodule, welche f{\"u}r unterschiedlichste r{\"a}umliche Gegebenheiten skaliert werden k{\"o}nnen. Somit k{\"o}nnen Einrichtungen neue Funktionalit{\"a}ten integrieren oder auf tempor{\"a}re Anforderungen strategisch reagieren. Durch die einfache Montage und Transportf{\"a}higkeit lassen sich sehr schnell zeitbegrenzte oder dauerhafte Raumkonzepte umsetzen. Das System nimmt die Dynamik des sich ver{\"a}ndernden Bedarfs auf und passt sich flexibel den Zielgruppen an, was im Gegensatz dazu bei statischen Systemen nicht der Fall ist.},
  language  = {de}
}
@masterthesis{Krier2021,
  type      = {Bachelor Thesis},
  author    = {Krier, Tessy},
  title     = {Entwicklung eines Multifunktionsdrucksystems nach dem Modell der Kreislaufwirtschaft},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {159 Seiten},
  year      = {2021},
  abstract  = {„Printen" ist ein Multifunktionsdrucksystem, welches dem Nutzer erm{\"o}glicht, es zu reparieren. Das Elektroschrottaufkommen der Welt steigt, deshalb legte die EU neue Maßnahmen zum {\"O}kodesign fest. Diese sollen die Reparierbarkeit von Produkten f{\"o}rdern und geplante Obsoleszenz unterbinden. Ein Vorzeigebeispiel f{\"u}r geplanten Obsoleszenz ist der Drucker. Das System besteht aus einem Drucker und Scanner, an dem der Nutzer Reparaturen vornehmen kann. Dadurch soll eine st{\"a}rkere Bindung zum selbst reparierten Ger{\"a}t entstehen und die Lebensdauer verl{\"a}ngert werden. Durch ein {\"o}ffnungsf{\"a}higes Geh{\"a}use wird die Reparatur erm{\"o}glicht. Eine Farbcodierung im Inneren erleichtert die Orientierung und visualisiert zusammengeh{\"o}rende Elemente. Außerdem wurde der Aufbau des Druckers aufger{\"a}umt und vereinfacht. So k{\"o}nnen einzelne Komponenten problemlos ausgetauscht werden. Ganz nach der Devise: Einfach printen!},
  language  = {de}
}