@article{BaeckerSchusserPoghossianetal.2014, author = {B{\"a}cker, Matthias and Schusser, Sebastian and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Multi-Parametererfassung mit siliziumbasiertem Sensorchip: Aus Drei mach Eins}, series = {GIT Labor-Fachzeitschrift}, journal = {GIT Labor-Fachzeitschrift}, number = {2}, publisher = {Wiley}, issn = {0016-3538}, pages = {28 -- 30}, year = {2014}, language = {de} } @article{WiesenTippkoetterMuffleretal.2014, author = {Wiesen, Sebastian and Tippk{\"o}tter, Nils and Muffler, Kai and Suck, Kirstin and Sohling, Ulrich and Ruf, Nils and Ulber, Roland}, title = {Adsorptive Vorbehandlung von Rohglycerin f{\"u}r die 1,3-Propandiol Fermentation mit Clostridium diolis}, series = {Chemie Ingenieur Technik}, volume = {86}, journal = {Chemie Ingenieur Technik}, number = {1-2}, publisher = {Wiley-VCH}, address = {Weinheim}, doi = {10.1002/cite.201300080}, pages = {129 -- 135}, year = {2014}, abstract = {Bei der Gewinnung von Fetts{\"a}uren aus Pflanzen{\"o}len, z. B. zur Herstellung von Biopolymeren, oder bei der Biodiesel- und Seifenproduktion, f{\"a}llt Glycerin als Nebenprodukt an. Bei der Biokonversion dieses Rohstoffes zu 1,3-Propandiol wird der Produktionsorganismus Clostridium diolis durch Verunreinigungen im Rohglycerin gehemmt. Als inhibierende Substanzen konnten freie Fetts{\"a}uren identifiziert werden. Mithilfe eines adsorptiven Aufarbeitungsverfahrens ist es gelungen, die Fetts{\"a}uren zu entfernen und die Konversionseffizienz zu 1,3-Propandiol zu erh{\"o}hen.}, language = {de} } @article{LevesqueSiegwolfEilmannetal.2014, author = {L{\´e}vesque, Mathieu and Siegwolf, Rolf and Eilmann, Britta and Saurer, Matthias and Rigling, Andreas}, title = {Increased water-use efficiency does not lead to enhanced tree growth under xeric and mesic conditions}, series = {New Phytologist}, volume = {203}, journal = {New Phytologist}, number = {1}, publisher = {Wiley-Blackwell}, address = {Oxford}, issn = {1469-8137 (Online)}, doi = {10.1111/nph.12772}, pages = {94 -- 109}, year = {2014}, language = {en} } @article{HafnerDemetzWeickertetal.2014, author = {Hafner, David and Demetz, Oliver and Weickert, Joachim and Reißel, Martin}, title = {Mathematical Foundations and Generalisations of the Census Transform for Robust Optic Flow Computation}, series = {Journal of Mathematical Imaging and Vision}, journal = {Journal of Mathematical Imaging and Vision}, publisher = {Springer}, address = {New York}, issn = {1573-7683 (Online)}, doi = {10.1007/s10851-014-0529-9}, year = {2014}, language = {en} } @article{Finkenberger2014, author = {Finkenberger, Isabel Maria}, title = {Vox populi. (Transformations-)potenziale nachkriegsmoderner Freiraumressourcen}, series = {Stadt+Gr{\"u}n}, volume = {2014}, journal = {Stadt+Gr{\"u}n}, number = {1}, publisher = {Patzer}, address = {Berlin}, issn = {0948-9770}, pages = {31 -- 35}, year = {2014}, abstract = {Heute wie damals werden die großz{\"u}gigen und offenen Siedlungsstrukturen der ersten Nachkriegsjahrzehnte mit ihrem hohen Anteil an "Gr{\"u}n" vielfach gesch{\"a}tzt und als solche nicht grundlegend hinterfragt. "Gr{\"u}n" verheißt im Allgemeinen Licht, Luft und Sonne, Freizeit und Erholung und gilt als etwas W{\"u}nschenswertes im st{\"a}dtischen Kontext. Unbeachtet bleibt, dass dem Begriff "Gr{\"u}n" zun{\"a}chst keine Eigenschaften oder Qualit{\"a}ten zugewiesen sind - er sagt noch lange nichts {\"u}ber dessen r{\"a}umliche Qualit{\"a}t, dessen Nutzbarkeit, Erreichbarkeit und Zug{\"a}nglichkeit aus. Abstandsgr{\"u}n und Straßenbegleitgr{\"u}n ist eben auch "Gr{\"u}n". Neben einer quantitativen Argumentation, welche {\"o}kologischen Aspekte wie Biotopvernetzung, Stadt- und Mikroklima ber{\"u}cksichtigt, sollten wir verst{\"a}rkt qualitativ denken und damit die Grundlage f{\"u}r einen erweiterten und wesentlich differenzierteren Diskurs {\"u}ber urbane Freir{\"a}ume ebnen.}, language = {de} } @article{Stulpe2014, author = {Stulpe, Werner}, title = {From the attempt of certain classical reformulations of quantum mechanics to quasi-probability representations}, series = {Journal of Mathematical Physics}, volume = {55}, journal = {Journal of Mathematical Physics}, number = {1}, publisher = {AIP Publishing}, address = {College Park, Md.}, issn = {222-488}, doi = {10.1063/1.4861939}, pages = {Artikel 012109}, year = {2014}, abstract = {The concept of an injective affine embedding of the quantum states into a set of classical states, i.e., into the set of the probability measures on some measurable space, as well as its relation to statistically complete observables is revisited, and its limitation in view of a classical reformulation of the statistical scheme of quantum mechanics is discussed. In particular, on the basis of a theorem concerning a non-denseness property of a set of coexistent effects, it is shown that an injective classical embedding of the quantum states cannot be supplemented by an at least approximate classical description of the quantum mechanical effects. As an alternative approach, the concept of quasi-probability representations of quantum mechanics is considered.}, language = {en} } @article{AlKaidyDuweHusteretal.2014, author = {Al-Kaidy, Huschyar and Duwe, Anna and Huster, Manuel and Muffler, Kai and Schlegel, Christin and Sieker, Tim and Stadtm{\"u}ller, Ralf and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Biotechnologie und Bioverfahrenstechnik - Vom ersten Ullmanns Artikel bis hin zu aktuellen Forschungsthemen}, series = {Chemie Ingenieur Technik}, volume = {86}, journal = {Chemie Ingenieur Technik}, number = {12}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201400083}, pages = {2215 -- 2225}, year = {2014}, abstract = {Biotechnologie und die mit ihr verbundenen technischen Prozesse pr{\"a}gen seit Jahrtausenden die Entwicklung der Menschheit. Ausgehend von empirischen Verfahren, insbesondere zur Herstellung von Lebensmitteln und t{\"a}glichen Gebrauchsg{\"u}tern, haben sich diese Disziplinen zu einem der innovativsten Zukunftsfelder entwickelt. Durch das immer detailliertere Verst{\"a}ndnis zellul{\"a}rer Vorg{\"a}nge k{\"o}nnen mittlerweile Produktionsst{\"a}mme gezielt optimiert werden. Im Zusammenspiel mit moderner Prozesstechnik k{\"o}nnen so eine Vielzahl von Bulk- und Feinchemikalien sowie Pharmazeutika effizient hergestellt werden. In diesem Artikel werden exemplarisch einige der aktuellen Trends vorgestellt.}, language = {de} } @article{PasteurTippkoetterKampeisetal.2014, author = {Pasteur, Aline and Tippk{\"o}tter, Nils and Kampeis, Percy and Ulber, Roland}, title = {Optimization of high gradient magnetic separation filter units for the purification of fermentation products}, series = {IEEE TRANSACTIONS ON MAGNETICS}, volume = {50}, journal = {IEEE TRANSACTIONS ON MAGNETICS}, number = {10}, publisher = {IEEE}, address = {New York, NY}, issn = {0018-9464}, doi = {10.1109/TMAG.2014.2325535}, pages = {Artikel 5000607}, year = {2014}, abstract = {High gradient magnetic separation (HGMS) has been established since the early 1970s. A more recent application of these systems is the use in bioprocesses. To integrate the HGMS in a fermentation process, it is necessary to optimize the separation matrix with regard to the magnetic separation characteristics and permeability of the non-magnetizable components of the fermentation broth. As part of the work presented here, a combined fluidic and magnetic force finite element model simulation was created using the software COMSOL Multiphysics and compared with separation experiments. Finally, as optimal lattice orientation of the separation matrix, a transversal rhombohedral arrangement was defined. The high suitability of the new filter matrix has been verified by separation experiments.}, language = {en} } @article{Golland2014, author = {Golland, Alexander}, title = {Datenschutz durch modulare Zertifizierung: Trusted Cloud-Pilotprojekt bringt neuen Ansatz}, series = {DSB Datenschutz-Berater}, volume = {38}, journal = {DSB Datenschutz-Berater}, number = {10}, publisher = {DFV Mediengruppe}, address = {Frankfurt a.M.}, isbn = {0170-7256}, pages = {213 -- 215}, year = {2014}, language = {de} } @article{LuisierLempiaeinenScherbichleretal.2014, author = {Luisier, Rapha{\"e}lle and Lempi{\"a}inen, Harri and Scherbichler, Nina and Braeuning, Albert and Geissler, Miriam and Dubost, Valerie and M{\"u}ller, Arne and Scheer, Nico and Chibout, Salah-Dine and Hara, Hisanori and Picard, Frank and Theil, Diethilde and Couttet, Philippe and Vitobello, Antonio and Grenet, Olivier and Grasl-Kraupp, Bettina and Ellinger-Ziegelbauer, Heidrung and Thomson, John P. and Meehan, Richard R. and Elcombe, Clifford R. and Henderson, Colin J. and Wolf, C. Roland and Schwarz, Michael and Moulin, Pierre and Terranova, Remi and Moggs, Jonathan G.}, title = {Phenobarbital Induces Cell Cycle Transcriptional Responses in Mouse Liver Humanized for Constitutive Androstane and Pregnane X Receptors}, series = {Toxicological Sciences}, volume = {139}, journal = {Toxicological Sciences}, number = {2}, publisher = {Oxford University Press}, address = {Oxford}, issn = {1094-2025}, doi = {https://doi.org/10.1093/toxsci/kfu038}, pages = {501 -- 511}, year = {2014}, abstract = {The constitutive androstane receptor (CAR) and the pregnane X receptor (PXR) are closely related nuclear receptors involved in drug metabolism and play important roles in the mechanism of phenobarbital (PB)-induced rodent nongenotoxic hepatocarcinogenesis. Here, we have used a humanized CAR/PXR mouse model to examine potential species differences in receptor-dependent mechanisms underlying liver tissue molecular responses to PB. Early and late transcriptomic responses to sustained PB exposure were investigated in liver tissue from double knock-out CAR and PXR (CARᴷᴼ-PXRᴷᴼ), double humanized CAR and PXR (CARʰ-PXRʰ), and wild-type C57BL/6 mice. Wild-type and CARʰ-PXRʰ mouse livers exhibited temporally and quantitatively similar transcriptional responses during 91 days of PB exposure including the sustained induction of the xenobiotic response gene Cyp2b10, the Wnt signaling inhibitor Wisp1, and noncoding RNA biomarkers from the Dlk1-Dio3 locus. Transient induction of DNA replication (Hells, Mcm6, and Esco2) and mitotic genes (Ccnb2, Cdc20, and Cdk1) and the proliferation-related nuclear antigen Mki67 were observed with peak expression occurring between 1 and 7 days PB exposure. All these transcriptional responses were absent in CARᴷᴼ-PXRᴷᴼ mouse livers and largely reversible in wild-type and CARʰ-PXRʰ mouse livers following 91 days of PB exposure and a subsequent 4-week recovery period. Furthermore, PB-mediated upregulation of the noncoding RNA Meg3, which has recently been associated with cellular pluripotency, exhibited a similar dose response and perivenous hepatocyte-specific localization in both wild-type and CARʰ-PXRʰ mice. Thus, mouse livers coexpressing human CAR and PXR support both the xenobiotic metabolizing and the proliferative transcriptional responses following exposure to PB.}, language = {en} }