@article{BlockMayWetzeletal.2023,
  author    = {Block, Franziska and May, Alexander and Wetzel, Katharina and Adels, Klaudia and Elbers, Gereon and Schulze, Margit and Monakhova, Yulia},
  title     = {What is the best spectroscopic method for simultaneous analysis of organic acids and (poly)saccharides in biological matrices: Example of Aloe vera extracts?},
  series = {Talanta Open},
  volume    = {7},
  journal   = {Talanta Open},
  number    = {Art. No. 100220},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2666-8319},
  doi       = {10.1016/j.talo.2023.100220},
  pages     = {1 -- 9},
  year      = {2023},
  abstract  = {Several species of (poly)saccharides and organic acids can be found often simultaneously in various biological matrices, e.g., fruits, plant materials, and biological fluids. The analysis of such matrices sometimes represents a challenging task. Using Aloe vera (A. vera) plant materials as an example, the performance of several spectro-scopic methods (80 MHz benchtop NMR, NIR, ATR-FTIR and UV-vis) for the simultaneous analysis of quality parameters of this plant material was compared. The determined parameters include (poly)saccharides such as aloverose, fructose and glucose as well as organic acids (malic, lactic, citric, isocitric, acetic, fumaric, benzoic and sorbic acids). 500 MHz NMR and high-performance liquid chromatography (HPLC) were used as the reference methods. UV-vis data can be used only for identification of added preservatives (benzoic and sorbic acids) and drying agent (maltodextrin) and semiquantitative analysis of malic acid. NIR and MIR spectroscopies combined with multivariate regression can deliver more informative overview of A. vera extracts being able to additionally quantify glucose, aloverose, citric, isocitric, malic, lactic acids and fructose. Low-field NMR measurements can be used for the quantification of aloverose, glucose, malic, lactic, acetic, and benzoic acids. The benchtop NMR method was successfully validated in terms of robustness, stability, precision, reproducibility and limit of detection (LOD) and quantification (LOQ), respectively. All spectroscopic techniques are useful for the screening of (poly)saccharides and organic acids in plant extracts and should be applied according to its availability as well as information and confidence required for the specific analytical goal. Benchtop NMR spectroscopy seems to be the most feasible solution for quality control of A. vera products.},
  language  = {en}
}
@article{AdelsElbersDiehletal.2023,
  author    = {Adels, Klaudia and Elbers, Gereon and Diehl, Bernd and Monakhova, Yulia},
  title     = {Multicomponent analysis of dietary supplements containing glucosamine and chondroitin: comparative low- and high-field NMR spectroscopic study},
  series = {Analytical Sciences},
  volume    = {2023},
  journal   = {Analytical Sciences},
  publisher = {Springer Verlag},
  address   = {Cham},
  issn      = {1348-2246 (Online)},
  doi       = {10.1007/s44211-023-00433-2},
  pages     = {13 Seiten},
  year      = {2023},
  abstract  = {With the prevalence of glucosamine- and chondroitin-containing dietary supplements for people with osteoarthritis in the marketplace, it is important to have an accurate and reproducible analytical method for the quantitation of these compounds in finished products. NMR spectroscopic method based both on low- (80 MHz) and high- (500-600 MHz) field NMR instrumentation was established, compared and validated for the determination of chondroitin sulfate and glucosamine in dietary supplements. The proposed method was applied for analysis of 20 different dietary supplements. In the majority of cases, quantification results obtained on the low-field NMR spectrometer are similar to those obtained with high-field 500-600 MHz NMR devices. Validation results in terms of accuracy, precision, reproducibility, limit of detection and recovery demonstrated that the developed method is fit for purpose for the marketed products. The NMR method was extended to the analysis of methylsulfonylmethane, adulterant maltodextrin, acetate and inorganic ions. Low-field NMR can be a quicker and cheaper alternative to more expensive high-field NMR measurements for quality control of the investigated dietary supplements. High-field NMR instrumentation can be more favorable for samples with complex composition due to better resolution, simultaneously giving the possibility of analysis of inorganic species such as potassium and chloride.},
  language  = {en}
}
@article{TrappLammersEngudaretal.2023,
  author    = {Trapp, Svenja and Lammers, Tom and Engudar, Gokce and Hoehr, Cornelia and Denkova, Antonia G. and Paulßen, Elisabeth and de Kruijff, Robin M.},
  title     = {Membrane-based microfluidic solvent extraction of Ga-68 from aqueous Zn solutions: towards an automated cyclotron production loop},
  series = {EJNMMI Radiopharmacy and Chemistry},
  volume    = {2023},
  journal   = {EJNMMI Radiopharmacy and Chemistry},
  number    = {8, Article number: 9},
  publisher = {Springer Nature},
  issn      = {2365-421X},
  doi       = {10.1186/s41181-023-00195-2},
  pages     = {1 -- 14},
  year      = {2023},
  language  = {en}
}
@masterthesis{Hosseinpour2023,
  type      = {Bachelor Thesis},
  author    = {Hosseinpour, Seywan},
  title     = {Velum : Zensur des Visuellen im Iran},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {153 Seiten},
  year      = {2023},
  abstract  = {Dieses multimediale Projekt thematisiert Zensur aus verschiedenen Dimensionen in totalit{\"a}ren, religi{\"o}s-patriarchalischen L{\"a}ndern, insbesondere im Iran. Dadurch wird versucht, mit einem denunzierenden Ansatz zu zeigen, wie Bilder zensiert werden und welche Auswirkungen diese zensierten Bilder auf Betrachter:innen haben. Dabei ist es auch wichtig, wie das Unsichtbare analysiert und verstanden wird. Die Opposition zwischen dem Akt des Visualisierens/Sichtbarmachens und Verbergens/Unsichtbarmachens in den meisten Bildern impliziert die Dialektik von Verh{\"u}llung und Enth{\"u}llung. Das Projekt »Velum« erm{\"o}glicht es den Betrachter:innen, die Zensurpraktiken in totalit{\"a}r-religi{\"o}sen L{\"a}ndern kennenzulernen und zu erfahren, inwieweit die Zensur das t{\"a}gliche Leben durchdrungen und beeinflusst hat -in der Kunst, der Literatur, den Medien usw. Ein Ph{\"a}nomen, das sogar die Privatsph{\"a}re des Individuums beeintr{\"a}chtigt.},
  language  = {de}
}
@masterthesis{Kilcher2023,
  type      = {Bachelor Thesis},
  author    = {Kilcher, Mathias},
  title     = {Barrierefreies Klettern : ein System zur Inklusion sehbehinderter Menschen in den Klettersport},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {135 Seiten},
  year      = {2023},
  abstract  = {Ziel des Projekts war die Entwicklung eines Systems, das es Menschen mit starker Sehbehinderung erm{\"o}glicht, Klettersport als ein Training f{\"u}r ihren K{\"o}rper und ihren Orientierungssinn nutzen zu k{\"o}nnen. Inklusion ist als gesellschaftliches Thema in den letzten Jahren stark in den Fokus ger{\"u}ckt. Dennoch ist es f{\"u}r Menschen mit Behinderung oft schwer, sozialen Anschluss zu finden. Dies wird zus{\"a}tzlich durch das mangelnde Angebot an inklusiven Freizeitaktivit{\"a}ten erschwert. Apollon erm{\"o}glicht Menschen mit starker Sehbehinderung die Orientierung w{\"a}hrend des Kletterns, indem es einerseits Informationen vermittelt, die normalerweise nur visuell wahrgenommen werden k{\"o}nnen und andererseits dabei hilft, sich besser an bereits gekletterte Routen zu erinnern. Das System setzt sich aus 3 Komponenten zusammen. Die Tritthilfen helfen der blinden Person dabei, auch kleine Tritte zu finden. Die taktilen Wegmarken stellen eine Art Checkpoint dar und helfen der blinden Person dabei, die Route in mehrere Abschnitte zu unterteilen. Gleichzeitig weisen sie darauf hin, welches Feature die kletternde Person erwartet. Die taktile Karte ist modular aufgebaut und setzt sich aus einer Legende und den Repr{\"a}sentanten der Wegmarken einer Route zusammen. Analog zu dem Betrachten der Route ist die blinde Person so vor dem Klettern in der Lage, Informationen {\"u}ber die Route zu erfahren.},
  language  = {de}
}
@masterthesis{Farjam2023,
  type      = {Bachelor Thesis},
  author    = {Farjam, Ina},
  title     = {Farfilia : experimenteller Tanzfilm {\"u}ber eine Vater-Tochter-Beziehung},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {61 Seiten},
  year      = {2023},
  abstract  = {Der experimentelle Tanzfilm „Farfilia" behandelt die Beziehung einer Tochter zu ihrem Vater. Beide Parteien funktionieren sehr unterschiedlich, denken, kommunizieren und leben in v{\"o}llig verschiedenen Welten. Es findet ein Konflikt zwischen den Generationen statt, zwischen zwei sehr gegens{\"a}tzlichen Pr{\"a}gungen und Charakteren. Die zwei Welten unterscheiden sich nicht nur in ihrer Visualit{\"a}t, sondern durch die in ihr lebenden und handelnden zwei Hauptprotagonist*innen, welches bildgestalterisch durch ein Zusammenspiel von Cinematographie, Choreographie und Setting ausgearbeitet und dargestellt wird. Durch die gemeinsame Wirkung vieler unterschiedlicher Gestaltungsmittel soll eine Geschichte erz{\"a}hlt werden, in der sich beide Welten aufeinander zu bewegen und am Ende Elemente der jeweils anderen Welt in sich aufnehmen und f{\"u}r die eigene Empfindung in der jeweiligen Umgebung adaptieren.},
  language  = {de}
}
@masterthesis{Leiwen2023,
  type      = {Bachelor Thesis},
  author    = {Leiwen, Sophie},
  title     = {Steinreich : Mineralien des Siegerlands},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {69 Seiten},
  year      = {2023},
  abstract  = {Der Aufbau und die Entstehung unseres Planeten sind untrennbar mit der Bildung von Gesteinen verbunden - diese setzen sich aus verschiedenen Mineralien zusammen. Sie sind in der Natur weit verbreitet und spielen eine entscheidende Rolle in unserem t{\"a}glichen Leben. Obwohl vielen Menschen der Nutzen von Bodensch{\"a}tzen bewusst ist, besteht ein geringes Wissen {\"u}ber deren Vorkommen und Relevanz. F{\"u}r die wirtschaftliche Entwicklung des Siegerlandes beispielsweise waren der Abbau und der Handel mit Mineralien von großer Bedeutung. Insbesondere der langj{\"a}hrige Abbau von Eisenerz legte den Grundstein f{\"u}r die gesamte Metallindustrie der Region. Die Publikation visualisiert eine umfangreiche Sammlung Siegerl{\"a}nder Mineralien und vermittelt ein grundlegendes Verst{\"a}ndnis von Mineralien.},
  language  = {de}
}
@masterthesis{Martinez2023,
  type      = {Bachelor Thesis},
  author    = {Martinez, Mariana},
  title     = {The Taste of Memories : a recipe book of memories},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {110 Seiten},
  year      = {2023},
  abstract  = {What does the word 'home' means and at what age do we give it meaning? Many of us grew up in one, in a home that our parents, grandparents, aunts, uncles and relatives shaped. Who, as we grew up, taught us about the world from their perspective as we interpreted and saw it for the first time and with it, its colors, its smells, its tastes, its sounds, its dances, and its languages. When we migrate, we take all that with us, like a piece of luggage that was stored in some corner inside a lung, or inside the memory in a heart's artery. And then you arrive in this new world, which we were told was the Old World, with other colors, other flavors, other words, in which yours no longer make sense. And you try to connect with all your senses, but, above all, we try to belong, because we belonged all our lives to something, to someone, to some place where we learned to be. When we migrate, without saying, we go through the grieve that comes with the beautiful discomfort of leaving everything we once knew. We mourn, because we can't go to lunch at our grandmas on Sundays, or have mom bring us soup when we are sick, or the Christmas meals and celebrations that we like so much, or that special dish that was made for us on our birthdays or on a family BBQ on a Sunday or a holiday. I wonder if emotions come inside us through the taste and respiratory track, if it is that we breathe life, and with that what we love finds its ways inside and finds its corner somewhere in the body. If what we have loved and what we have lived hides somewhere in our body, I doubtlessly think it came in through one of our senses, and in this attempt at my first illustrated book I'll share which, I think, are the senses through which at first instance part of what we perceive as cultural identity enters.},
  language  = {de}
}
@article{FalkenbergVossBottetal.2023,
  author    = {Falkenberg, Fabian and Voß, Leonie and Bott, Michael and Bongaerts, Johannes and Siegert, Petra},
  title     = {New robust subtilisins from halotolerant and halophilic Bacillaceae},
  series = {Applied Microbiology and Biotechnology},
  volume    = {107},
  journal   = {Applied Microbiology and Biotechnology},
  publisher = {Springer Nature},
  address   = {Berlin},
  issn      = {1432-0614},
  doi       = {10.1007/s00253-023-12553-w},
  pages     = {3939 -- 3954},
  year      = {2023},
  abstract  = {The aim of the present study was the characterisation of three true subtilisins and one phylogenetically intermediate subtilisin from halotolerant and halophilic microorganisms. Considering the currently growing enzyme market for efficient and novel biocatalysts, data mining is a promising source for novel, as yet uncharacterised enzymes, especially from halophilic or halotolerant Bacillaceae, which offer great potential to meet industrial needs. Both halophilic bacteria Pontibacillus marinus DSM 16465ᵀ and Alkalibacillus haloalkaliphilus DSM 5271ᵀ and both halotolerant bacteria Metabacillus indicus DSM 16189 and Litchfieldia alkalitelluris DSM 16976ᵀ served as a source for the four new subtilisins SPPM, SPAH, SPMI and SPLA. The protease genes were cloned and expressed in Bacillus subtilis DB104. Purification to apparent homogeneity was achieved by ethanol precipitation, desalting and ion-exchange chromatography. Enzyme activity could be observed between pH 5.0-12.0 with an optimum for SPPM, SPMI and SPLA around pH 9.0 and for SPAH at pH 10.0. The optimal temperature for SPMI and SPLA was 70 °C and for SPPM and SPAH 55 °C and 50 °C, respectively. All proteases showed high stability towards 5\% (w/v) SDS and were active even at NaCl concentrations of 5 M. The four proteases demonstrate potential for future biotechnological applications.},
  language  = {en}
}
@inproceedings{ChircuCzarneckiFriedmannetal.2023,
  author    = {Chircu, Alina and Czarnecki, Christian and Friedmann, Daniel and Pomaskow, Johanna and Sultanow, Eldar},
  title     = {Towards a Digital Twin of Society},
  series = {Proceedings of the 56th Hawaii International Conference on System Sciences 2023},
  booktitle = {Proceedings of the 56th Hawaii International Conference on System Sciences 2023},
  publisher = {University of Hawai'i},
  address   = {Honolulu},
  isbn      = {978-0-9981331-6-4},
  pages     = {6748 -- 6757},
  year      = {2023},
  abstract  = {This paper describes the potential for developing a digital twin of society- a dynamic model that can be used to observe, analyze, and predict the evolution of various societal aspects. Such a digital twin can help governmental agencies and policy makers in interpreting trends, understanding challenges, and making decisions regarding investments or policies necessary to support societal development and ensure future prosperity. The paper reviews related work regarding the digital twin paradigm and its applications. The paper presents a motivating case study- an analysis of opportunities and challenges faced by the German federal employment agency, Bundesagentur f¨ur Arbeit (BA), proposes solutions using digital twins, and describes initial proofs of concept for such solutions.},
  language  = {en}
}