@article{ErmolaevNivokovMelnikovaetal.2018,
  author    = {Ermolaev, A.P. and Nivokov, I.A. and Melnikova, L.I. and Kotliar, Konstantin},
  title     = {Сравнительная характеристика химического состава витреального содержимого кадаверных глаз и глаз с рефрактерной терминальной глаукомой},
  series = {Vestnik oftalmologii},
  volume    = {5},
  journal   = {Vestnik oftalmologii},
  number    = {2},
  publisher = {Media Sfera},
  address   = {Moskau},
  doi       = {10.17116/oftalma2018134051195},
  pages     = {195 -- 201},
  year      = {2018},
  abstract  = {Purpose — to compare the chemical elemental composition of vitreous cavity content taken from cadaveric eyes compared to samples taken from the eyes with terminal stage refractory glaucoma with decompensated intraocular pressure (IOP). Material and methods. The vitreous contents of the eyes from 2 groups were studied. The 1st group included 15 cadaveric eyes; the 2nd group included 15 eyes with refractory glaucoma in the terminal stage of the disease with decompensated IOP in patients with hypertension pain. The vitreal content samples were taken in the course of antiglaucoma surgery aimed at preserving the eye as an organ and involving employment of drainage in the vitreous cavity. The study of virtual contents was carried out on energy dispersive spectrometer Oxford X-Max 50 integrated into scanning electron microscope Zeiss EVO LS10. Results. Increased concentrations of Kalium and Phosphorus were detected in the vitreous content of cadaveric eyes compared with the vitreal content from the eyes with terminal glaucoma with decompensated IOP taken in vivo (K — 0.172/0.093; P — 0.045/0.025 mmol/L). In the vitreous cavity in the eyes with end-stage glaucoma with decompensated IOP, the concentration of Nitrogen was higher in comparison with human cadaver eyes (2.030/1.424 mmol/L). Conclusion. The increased concentrations of Kalium and Phosphorus in the vitreous content of cadaveric eyes is associated with postmortem autolytic processes and with the release of intracellular content in the destruction of cell membranes. The increased Nitrogen concentration in the vitreal contents of the eyes with terminal stage glaucoma with decompensated IOP may be associated with the presence of osmotically active nitrogen-containing compounds in the eyes with increased IOP.},
  language  = {ru}
}
@article{KetelhutGoellBraunsteinetal.2018,
  author    = {Ketelhut, Maike and G{\"o}ll, Fabian and Braunstein, Bj{\"o}rn and Albracht, Kirsten and Abel, Dirk},
  title     = {Comparison of different training algorithms for the leg extension training with an industrial robot},
  series = {Current Directions in Biomedical Engineering},
  volume    = {4},
  journal   = {Current Directions in Biomedical Engineering},
  number    = {1},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {2364-5504},
  doi       = {10.1515/cdbme-2018-0005},
  pages     = {17 -- 20},
  year      = {2018},
  abstract  = {In the past, different training scenarios have been developed and implemented on robotic research platforms, but no systematic analysis and comparison have been done so far. This paper deals with the comparison of an isokinematic (motion with constant velocity) and an isotonic (motion against constant weight) training algorithm. Both algorithms are designed for a robotic research platform consisting of a 3D force plate and a high payload industrial robot, which allows leg extension training with arbitrary six-dimensional motion trajectories. In the isokinematic as well as the isotonic training algorithm, individual paths are defined i n C artesian s pace by sufficient s upport p oses. I n t he i sotonic t raining s cenario, the trajectory is adapted to the measured force as the robot should only move along the trajectory as long as the force applied by the user exceeds a minimum threshold. In the isotonic training scenario however, the robot's acceleration is a function of the force applied by the user. To validate these findings, a simulative experiment with a simple linear trajectory is performed. For this purpose, the same force path is applied in both training scenarios. The results illustrate that the algorithms differ in the force dependent trajectory adaption.},
  language  = {en}
}
@article{WerkhausenAlbrachtCroninetal.2018,
  author    = {Werkhausen, Amelie and Albracht, Kirsten and Cronin, Neil J and Paulsen, G{\o}ran and Bojsen-M{\o}ller, Jens and Seynnes, Olivier R},
  title     = {Effect of training-induced changes in achilles tendon stiffness on muscle-tendon behavior during landing},
  series = {Frontiers in physiology},
  journal   = {Frontiers in physiology},
  number    = {9},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-042X},
  doi       = {10.3389/fphys.2018.00794},
  pages     = {11 Seiten},
  year      = {2018},
  abstract  = {During rapid deceleration of the body, tendons buffer part of the elongation of the muscle-tendon unit (MTU), enabling safe energy dissipation via eccentric muscle contraction. Yet, the influence of changes in tendon stiffness within the physiological range upon these lengthening contractions is unknown. This study aimed to examine the effect of training-induced stiffening of the Achilles tendon on triceps surae muscle-tendon behavior during a landing task. Twenty-one male subjects were assigned to either a 10-week resistance-training program consisting of single-leg isometric plantarflexion (n = 11) or to a non-training control group (n = 10). Before and after the training period, plantarflexion force, peak Achilles tendon strain and stiffness were measured during isometric contractions, using a combination of dynamometry, ultrasound and kinematics data. Additionally, testing included a step-landing task, during which joint mechanics and lengths of gastrocnemius and soleus fascicles, Achilles tendon, and MTU were determined using synchronized ultrasound, kinematics and kinetics data collection. After training, plantarflexion strength and Achilles tendon stiffness increased (15 and 18\%, respectively), and tendon strain during landing remained similar. Likewise, lengthening and negative work produced by the gastrocnemius MTU did not change detectably. However, in the training group, gastrocnemius fascicle length was offset (8\%) to a longer length at touch down and, surprisingly, fascicle lengthening and velocity were reduced by 27 and 21\%, respectively. These changes were not observed for soleus fascicles when accounting for variation in task execution between tests. These results indicate that a training-induced increase in tendon stiffness does not noticeably affect the buffering action of the tendon when the MTU is rapidly stretched. Reductions in gastrocnemius fascicle lengthening and lengthening velocity during landing occurred independently from tendon strain. Future studies are required to provide insight into the mechanisms underpinning these observations and their influence on energy dissipation.},
  language  = {en}
}
@article{AlbannaKotliarLuekeetal.2018,
  author    = {Albanna, Walid and Kotliar, Konstantin and L{\"u}ke, Jan Niklas and Alpdogan, Serdar and Conzen, Catharina and Lindauer, Ute and Clusmann, Hans and Hescheler, J{\"u}rgen and Vilser, Walthard and Schneider, Toni and Schubert, Gerrit Alexander},
  title     = {Non-invasive evaluation of neurovascular coupling in the murine retina by dynamic retinal vessel analysis},
  series = {Plos one},
  volume    = {13},
  journal   = {Plos one},
  number    = {10},
  publisher = {PLOS},
  address   = {San Francisco},
  doi       = {10.1371/journal.pone.0204689},
  pages     = {e0204689},
  year      = {2018},
  abstract  = {Background Impairment of neurovascular coupling (NVC) was recently reported in the context of subarachnoid hemorrhage and may correlate with disease severity and outcome. However, previous techniques to evaluate NVC required invasive procedures. Retinal vessels may represent an alternative option for non-invasive assessment of NVC. Methods A prototype of an adapted retinal vessel analyzer was used to assess retinal vessel diameter in mice. Dynamic vessel analysis (DVA) included an application of monochromatic flicker light impulses in predefined frequencies for evaluating NVC. All retinae were harvested after DVA and electroretinograms were performed. Results A total of 104 retinal scans were conducted in 21 male mice (90 scans). Quantitative arterial recordings were feasible only in a minority of animals, showing an emphasized reaction to flicker light impulses (8 mice; 14 scans). A characteristic venous response to flicker light, however, could observed in the majority of animals. Repeated measurements resulted in a significant decrease of baseline venous diameter (7 mice; 7 scans, p < 0.05). Ex-vivo electroretinograms, performed after in-vivo DVA, demonstrated a significant reduction of transretinal signaling in animals with repeated DVA (n = 6, p < 0.001). Conclusions To the best of our knowledge, this is the first non-invasive study assessing murine retinal vessel response to flicker light with characteristic changes in NVC. The imaging system can be used for basic research and enables the investigation of retinal vessel dimension and function in control mice and genetically modified animals.},
  language  = {en}
}
@article{HacklAndermahrStaatetal.2017,
  author    = {Hackl, M. and Andermahr, J. and Staat, Manfred and Bremer, I. and Borggrefe, J. and Prescher, A. and M{\"u}ller, L. P. and Wegmann, K.},
  title     = {Suture button reconstruction of the central band of the interosseous membrane in Essex-Lopresti lesions: a comparative biomechanical investigation},
  series = {The Journal of Hand Surgery (European Volume)},
  volume    = {42},
  journal   = {The Journal of Hand Surgery (European Volume)},
  number    = {4},
  publisher = {Sage},
  address   = {London},
  issn      = {2043-6289 (Online)},
  doi       = {10.1177/1753193416665943},
  pages     = {370 -- 376},
  year      = {2017},
  language  = {en}
}
@article{LanzlKotliar2017,
  author    = {Lanzl, I. and Kotliar, Konstantin},
  title     = {K{\"o}nnen Anti-VEGF-Injektionen Glaukom oder okul{\"a}re Hypertension verursachen?},
  series = {Klinische Monatsbl{\"a}tter f{\"u}r Augenheilkunde},
  volume    = {234},
  journal   = {Klinische Monatsbl{\"a}tter f{\"u}r Augenheilkunde},
  number    = {2},
  publisher = {Thieme},
  address   = {Stuttgart},
  issn      = {0023-2165},
  doi       = {10.1055/s-0043-101819},
  pages     = {191 -- 193},
  year      = {2017},
  language  = {de}
}
@article{HacklWegmannKahmannetal.2017,
  author    = {Hackl, Michael and Wegmann, Kilian and Kahmann, Stephanie Lucina and Heinze, Nicolai and Staat, Manfred and Neiss, Wolfram F. and Scaal, Martin and M{\"u}ller, Lars P.},
  title     = {Radial shortening osteotomy reduces radiocapitellar contact pressures while preserving valgus stability of the elbow},
  series = {Knee Surgery, Sports Traumatology, Arthroscopy},
  volume    = {25},
  journal   = {Knee Surgery, Sports Traumatology, Arthroscopy},
  number    = {7},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1433-7347},
  doi       = {10.1007/s00167-017-4468-z},
  pages     = {2280 -- 2288},
  year      = {2017},
  language  = {en}
}
@article{ZangeSchopenAlbrachtetal.2017,
  author    = {Zange, Jochen and Schopen, Kathrin and Albracht, Kirsten and Gerlach, Darius A. and Frings-Meuthen, Petra and Maffiuletti, Nicola A. and Bloch, Wilhelm and Rittweger, J{\"o}rn},
  title     = {Using the Hephaistos orthotic device to study countermeasure effectiveness of neuromuscular electrical stimulation and dietary lupin protein supplementation, a randomised controlled trial},
  series = {Plos one},
  volume    = {12},
  journal   = {Plos one},
  number    = {2},
  doi       = {10.1371/journal.pone.0171562},
  year      = {2017},
  language  = {en}
}
@article{MichaelMayerWeberetal.2017,
  author    = {Michael, Hackl and Mayer, Katharina and Weber, Mareike and Staat, Manfred and van Riet, Roger and Burkhart, Klau Josef and M{\"u}ller, Lars Peter and Wegmann, Kilian},
  title     = {Plate osteosynthesis of proximal ulna fractures : a biomechanical micromotion analysis},
  series = {The journal of hand surgery},
  volume    = {42},
  journal   = {The journal of hand surgery},
  number    = {10},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0363-5023},
  doi       = {10.1016/j.jhsa.2017.05.014},
  pages     = {834.e1 -- 834.e7},
  year      = {2017},
  language  = {en}
}
@article{HorbachDuongStaat2017,
  author    = {Horbach, Andreas and Duong, Minh Tuan and Staat, Manfred},
  title     = {Modelling of compressible and orthotropic surgical mesh implants based on optical deformation measurement},
  series = {Journal of the mechanical behavior of biomedical materials},
  volume    = {74},
  journal   = {Journal of the mechanical behavior of biomedical materials},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1751-6161},
  doi       = {10.1016/j.jmbbm.2017.06.012},
  pages     = {400 -- 410},
  year      = {2017},
  language  = {en}
}