@article{OliveiraMolinnusBegingetal.2021, author = {Oliveira, Danilo A. and Molinnus, Denise and Beging, Stefan and Siqueira Jr, Jos{\´e} R. and Sch{\"o}ning, Michael Josef}, title = {Biosensor Based on Self-Assembled Films of Graphene Oxide and Polyaniline Using a Field-Effect Device Platform}, series = {physica status solidi (a) applications and materials science}, volume = {218}, journal = {physica status solidi (a) applications and materials science}, number = {13}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.202000747}, pages = {1 -- 9}, year = {2021}, abstract = {A new functionalization method to modify capacitive electrolyte-insulator-semiconductor (EIS) structures with nanofilms is presented. Layers of polyallylamine hydrochloride (PAH) and graphene oxide (GO) with the compound polyaniline:poly(2-acrylamido-2-methyl-1-propanesulfonic acid) (PANI:PAAMPSA) are deposited onto a p-Si/SiO2 chip using the layer-by-layer technique (LbL). Two different enzymes (urease and penicillinase) are separately immobilized on top of a five-bilayer stack of the PAH:GO/PANI:PAAMPSA-modified EIS chip, forming a biosensor for detection of urea and penicillin, respectively. Electrochemical characterization is performed by constant capacitance (ConCap) measurements, and the film morphology is characterized by atomic force microscopy (AFM) and scanning electron microscopy (SEM). An increase in the average sensitivity of the modified biosensors (EIS-nanofilm-enzyme) of around 15\% is found in relation to sensors, only carrying the enzyme but without the nanofilm (EIS-enzyme). In this sense, the nanofilm acts as a stable bioreceptor onto the EIS chip improving the output signal in terms of sensitivity and stability.}, language = {en} } @article{WeldenNagamineKomesuWagneretal.2021, author = {Welden, Rene and Nagamine Komesu, Cindy A. and Wagner, Patrick H. and Sch{\"o}ning, Michael Josef and Wagner, Torsten}, title = {Photoelectrochemical enzymatic penicillin biosensor: A proof-of-concept experiment}, series = {Electrochemical Science Advances}, volume = {2}, journal = {Electrochemical Science Advances}, number = {4}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {2698-5977}, doi = {10.1002/elsa.202100131}, pages = {1 -- 5}, year = {2021}, abstract = {Photoelectrochemical (PEC) biosensors are a rather novel type of biosensors thatutilizelighttoprovideinformationaboutthecompositionofananalyte,enablinglight-controlled multi-analyte measurements. For enzymatic PEC biosensors,amperometric detection principles are already known in the literature. In con-trast, there is only a little information on H+-ion sensitive PEC biosensors. Inthis work, we demonstrate the detection of H+ions emerged by H+-generatingenzymes, exemplarily demonstrated with penicillinase as a model enzyme on atitanium dioxide photoanode. First, we describe the pH sensitivity of the sensorand study possible photoelectrocatalytic reactions with penicillin. Second, weshow the enzymatic PEC detection of penicillin.}, language = {en} } @article{RichterBraunsteinStaeudleetal.2021, author = {Richter, Charlotte and Braunstein, Bjoern and Staeudle, Benjamin and Attias, Julia and Suess, Alexander and Weber, Tobias and Mileva, Katya N. and Rittweger, Joern and Green, David A. and Albracht, Kirsten}, title = {Contractile behavior of the gastrocnemius medialis muscle during running in simulated hypogravity}, series = {npj Microgravity}, volume = {7}, journal = {npj Microgravity}, number = {Article number: 32}, publisher = {Springer Nature}, address = {New York}, issn = {2373-8065}, doi = {10.1038/s41526-021-00155-7}, pages = {7 Seiten}, year = {2021}, abstract = {Vigorous exercise countermeasures in microgravity can largely attenuate muscular degeneration, albeit the extent of applied loading is key for the extent of muscle wasting. Running on the International Space Station is usually performed with maximum loads of 70\% body weight (0.7 g). However, it has not been investigated how the reduced musculoskeletal loading affects muscle and series elastic element dynamics, and thereby force and power generation. Therefore, this study examined the effects of running on the vertical treadmill facility, a ground-based analog, at simulated 0.7 g on gastrocnemius medialis contractile behavior. The results reveal that fascicle-series elastic element behavior differs between simulated hypogravity and 1 g running. Whilst shorter peak series elastic element lengths at simulated 0.7 g appear to be the result of lower muscular and gravitational forces acting on it, increased fascicle lengths and decreased velocities could not be anticipated, but may inform the development of optimized running training in hypogravity. However, whether the alterations in contractile behavior precipitate musculoskeletal degeneration warrants further study.}, language = {en} } @article{Olbertz2021, author = {Olbertz, Klaus}, title = {Die Dienstreisezeit als Arbeitszeit - oder doch nicht? : Zur arbeitgeberfreundlichen Bewertung von Dienstreisezeiten durch das Bundesarbeitsgericht}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {1}, issn = {0028-3460}, pages = {38 -- 44}, year = {2021}, abstract = {Der arbeitsrechtlich richtige Umgang mit Zeiten einer Dienstreise kann in der betrieblichen Praxis Probleme bereiten. Ob die Reisezeiten als solche Arbeitszeit i. S. des Arbeitszeitgesetzes (ArbZG ) darstellen, also bspw. auf die t{\"a}gliche H{\"o}chstarbeitszeit angerechnet werden m{\"u}ssen oder nicht, ist oftmals genauso unklar wie die Frage, ob und inwieweit Reisezeiten verg{\"u}tungspflichtig sind. Aber auch, ob ein Arbeitnehmer {\"u}berhaupt zur Durchf{\"u}hrung einer Dienstreise verpflichtet werden kann, ist ein m{\"o}glicher Anlass von Streitigkeiten zwischen den Arbeitsvertragsparteien, wie verschiedene Gerichtsentscheidungen zeigen. Der nachfolgende Beitrag beantwortet die aufgeworfenen Fragen und gibt hierzu einen praxisorientierten {\"U}berblick.}, language = {de} } @article{HeinkeKnickerAlbracht2021, author = {Heinke, Lars N. and Knicker, Axel J. and Albracht, Kirsten}, title = {Test-retest reliability of the internal shoulder rotator muscles' stretch reflex in healthy men}, series = {Journal of Electromyography and Kinesiology}, volume = {62}, journal = {Journal of Electromyography and Kinesiology}, number = {Article 102611}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1050-6411}, doi = {10.1016/j.jelekin.2021.102611}, year = {2021}, abstract = {Until now the reproducibility of the short latency stretch reflex of the internal rotator muscles of the glenohumeral joint has not been identified. Twenty-three healthy male participants performed three sets of external shoulder rotation stretches with various pre-activation levels on two different dates of measurement to assess test-retest reliability. All stretches were applied with a dynamometer acceleration of 104°/s2 and a velocity of 150°/s. Electromyographical response was measured via surface EMG. Reflex latencies showed a pre-activation effect (ƞ2 = 0,355). ICC ranged from 0,735 to 0,909 indicating an overall "good" relative reliability. SRD 95\% lay between ±7,0 to ±12,3 ms.. The reflex gain showed overall poor test-retest reproducibility. The chosen methodological approach presented a suitable test protocol for shoulder muscles stretch reflex latency evaluation. A proof-of-concept study to validate the presented methodical approach in shoulder involvement including subjects with clinically relevant conditions is recommended.}, language = {en} } @article{HeelDiktaBraekers2021, author = {Heel, Mareike van and Dikta, Gerhard and Braekers, Roel}, title = {Bootstrap based goodness‑of‑fit tests for binary multivariate regression models}, series = {Journal of the Korean Statistical Society}, volume = {51}, journal = {Journal of the Korean Statistical Society}, publisher = {Springer Nature}, address = {Singapur}, issn = {2005-2863 (Online)}, doi = {10.1007/s42952-021-00142-4}, pages = {28 Seiten}, year = {2021}, abstract = {We consider a binary multivariate regression model where the conditional expectation of a binary variable given a higher-dimensional input variable belongs to a parametric family. Based on this, we introduce a model-based bootstrap (MBB) for higher-dimensional input variables. This test can be used to check whether a sequence of independent and identically distributed observations belongs to such a parametric family. The approach is based on the empirical residual process introduced by Stute (Ann Statist 25:613-641, 1997). In contrast to Stute and Zhu's approach (2002) Stute \& Zhu (Scandinavian J Statist 29:535-545, 2002), a transformation is not required. Thus, any problems associated with non-parametric regression estimation are avoided. As a result, the MBB method is much easier for users to implement. To illustrate the power of the MBB based tests, a small simulation study is performed. Compared to the approach of Stute \& Zhu (Scandinavian J Statist 29:535-545, 2002), the simulations indicate a slightly improved power of the MBB based method. Finally, both methods are applied to a real data set.}, language = {en} } @article{Timme2021, author = {Timme, Michael}, title = {Rechtsprechungs{\"u}bersicht zum Wohnraummietrecht}, series = {Monatsschrift f{\"u}r Deutsches Recht}, volume = {75}, journal = {Monatsschrift f{\"u}r Deutsches Recht}, number = {1}, publisher = {Verlag Dr. Otto Schmidt}, address = {K{\"o}ln}, issn = {2194-4202}, doi = {10.9785/mdtr-2021-750113}, pages = {6 -- 11}, year = {2021}, language = {de} } @article{ZabirovSchleserBucherer2021, author = {Zabirov, Alexander and Schleser, Markus and Bucherer, Sebastian}, title = {F{\"u}ge- und Dichtkonzept f{\"u}r einen Leichtbauverbrennungsmotor}, series = {adh{\"a}sion KLEBEN \& DICHTEN}, volume = {65}, journal = {adh{\"a}sion KLEBEN \& DICHTEN}, number = {11}, publisher = {Springer Nature}, address = {Cham}, issn = {2192-8681}, doi = {10.1007/s35145-021-0531-5}, pages = {12 -- 19}, year = {2021}, language = {de} } @article{Olbertz2021, author = {Olbertz, Klaus}, title = {Wichtige arbeitsrechtliche Entwicklungen im Jahr 2020 : Der Jahresr{\"u}ckblick auf alles Wissenswerte im Arbeitsrecht des vergangenen Jahres}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {10}, issn = {0028-3460}, pages = {703 -- 715}, year = {2021}, abstract = {Im Anschluss an die arbeitsrechtlichen Jahres{\"u}bersichten der vergangenen Jahre (NWB 5/2019 S. 266; NWB 8/2020 S. 557) gibt der nachfolgende Beitrag einen {\"U}berblick {\"u}ber relevante Entwicklungen im Arbeitsrecht des Jahres 2020. Der erste Teil besch{\"a}ftigt sich hierbei mit gesetzlichen {\"A}nderungen. Neben Regelungen, die auf die COVID-19-Pandemie zur{\"u}ckgef{\"u}hrt werden k{\"o}nnen, hat der Gesetzgeber auch andere Vorhaben umgesetzt. So wurde u. a. das Arbeitnehmerentsenderecht reformiert. F{\"u}r Diskussionen sorgt(e) zudem das Gesetzesvorhaben zur Regelung mobiler Arbeit. Im zweiten Teil werden f{\"u}r die Praxis wichtige h{\"o}chstrichterliche Gerichtsentscheidungen zum Arbeitsrecht erl{\"a}utert, alphabetisch sortiert von A (wie Antidiskriminierungsrecht) bis U (wie Urlaub).}, language = {de} } @article{Olbertz2021, author = {Olbertz, Klaus}, title = {Die Flexibilisierung von Arbeitszeit durch den Abruf von Arbeit : M{\"o}glichkeiten und Grenzen arbeitsvertraglicher Gestaltung zur Vermeidung von „Leerlaufzeiten"}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {15}, issn = {0028-3460}, pages = {1055 -- 1063}, year = {2021}, abstract = {Die Arbeitswelt ist im Umbruch. Der Bedarf an flexiblen Arbeitszeitmodellen nimmt stetig zu, wobei die Corona-Pandemie dieses Bed{\"u}rfnis nochmals versch{\"a}rft hat. Gerade auch in kleineren und mittleren Unternehmen w{\"a}chst die Notwendigkeit, den Einsatz der Besch{\"a}ftigten m{\"o}glichst bedarfsgerecht zu steuern, also bei guter Auftragslage mehr Arbeitszeit abzurufen und bei ausbleibenden Auftr{\"a}gen die Arbeitszeit zu reduzieren und somit bezahlte „Leerlaufzeiten" zu vermeiden. Der Gesetzgeber stellt den Arbeitgebern hierf{\"u}r das Instrument der sog. Abrufarbeit ( \S 12 Teilzeit- und Befristungsgesetz - TzBfG ) zur Verf{\"u}gung. In dem nachfolgenden Beitrag werden M{\"o}glichkeiten und Grenzen der Abrufarbeit skizziert und konkrete arbeitsvertragliche Gestaltungsm{\"o}glichkeiten aufgezeigt.}, language = {de} }