@article{KotterRiekertWeyland1983,
  author    = {Kotter, Michael and Riekert, L. and Weyland, F.},
  title     = {Deposition of ternary oxides as active components by impregnation of porous carriers},
  series = {Preparation of Catalysts III : scientific bases for the preparation of heterogeneous catalysts ; proceedings of the Third International Symposium, Louvain-la-Neuve, September 6-9, 1982 / ed.: G. Poncelet ... - (Studies in surface science and catalysis ; 16)},
  journal   = {Preparation of Catalysts III : scientific bases for the preparation of heterogeneous catalysts ; proceedings of the Third International Symposium, Louvain-la-Neuve, September 6-9, 1982 / ed.: G. Poncelet ... - (Studies in surface science and catalysis ; 16)},
  publisher = {Elsevier},
  address   = {Amsterdam [u.a.]},
  isbn      = {0-444-42184-X},
  pages     = {521 -- 530},
  year      = {1983},
  language  = {en}
}
@article{MuesgenanntKoersPrevostPaulssenetal.2023,
  author    = {Mues genannt Koers, Lucas and Prevost, David and Paulßen, Elisabeth and Hoehr, Cornelia},
  title     = {Density reduction effects on the production of [11C]CO2 in Nb-body targets on a medical cyclotron},
  volume    = {199},
  number    = {Art. 110911},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.apradiso.2023.110911},
  year      = {2023},
  abstract  = {Medical isotope production of 11C is commonly performed in gaseous targets. The power deposition of the proton beam during the irradiation decreases the target density due to thermodynamic mixing and can cause an increase of penetration depth and divergence of the proton beam. In order to investigate the difference how the target-body length influences the operation conditions and the production yield, a 12 cm and a 22 cm Nb-target body containing N2/O2 gas were irradiated using a 13 MeV proton cyclotron. It was found that the density reduction has a large influence on the pressure rise during irradiation and the achievable radioactive yield. The saturation activity of [11C]CO2 for the long target (0.083 Ci/μA) is about 10\% higher than in the short target geometry (0.075 Ci/μA).},
  language  = {en}
}
@article{PrielmeierRadkowitschLangetal.1986,
  author    = {Prielmeier, Franz and Radkowitsch, H. and Lang, E. W. and L{\"u}demann, H.-D.},
  title     = {Density dependence of the molecular dynamics of fluid CH3F and CF3H studied by NMR / H. Radkowitsch, F. X. Prielmeier, E. W. Lang and H.-D. L{\"u}demann},
  series = {Physica B+C. 139-140 (1986)},
  journal   = {Physica B+C. 139-140 (1986)},
  isbn      = {0921-4526},
  pages     = {96 -- 99},
  year      = {1986},
  language  = {en}
}
@article{ScheerMclaughlinRodeetal.2014,
  author    = {Scheer, Nico and Mclaughlin, Lesley A. and Rode, Anja and MacLeod, Alastair Kenneth and Henderson, Colin J. and Wolf, Roland C.},
  title     = {Deletion of thirty murine cytochrome P450 genes results in viable mice with compromised drug metabolism},
  series = {Drug Metabolism and Disposition},
  volume    = {42},
  journal   = {Drug Metabolism and Disposition},
  number    = {6},
  publisher = {ASPET},
  address   = {Bethesda, Md.},
  issn      = {1521-009X},
  doi       = {10.1124/dmd.114.057885},
  pages     = {1022 -- 1030},
  year      = {2014},
  abstract  = {In humans, 75\% of all drugs are metabolized by the cytochrome P450-dependent monooxygenase system. Enzymes encoded by the CYP2C, CYP2D, and CYP3A gene clusters account for ∼80\% of this activity. There are profound species differences in the multiplicity of cytochrome P450 enzymes, and the use of mouse models to predict pathways of drug metabolism is further complicated by overlapping substrate specificity between enzymes from different gene families. To establish the role of the hepatic and extrahepatic P450 system in drug and foreign chemical disposition, drug efficacy, and toxicity, we created a unique mouse model in which 30 cytochrome P450 genes from the Cyp2c, Cyp2d, and Cyp3a gene clusters have been deleted. Remarkably, despite a wide range of putative important endogenous functions, Cyp2c/2d/3a KO mice were viable and fertile, demonstrating that these genes have evolved primarily as detoxification enzymes. Although there was no overt phenotype, detailed examination showed Cyp2c/2d/3a KO mice had a smaller body size (15\%) and larger livers (20\%). Changes in hepatic morphology and a decreased blood glucose (30\%) were also noted. A five-drug cocktail of cytochrome P450 isozyme probe substrates were used to evaluate changes in drug pharmacokinetics; marked changes were observed in either the pharmacokinetics or metabolites formed from Cyp2c, Cyp2d, and Cyp3a substrates, whereas the metabolism of the Cyp1a substrate caffeine was unchanged. Thus, Cyp2c/2d/3a KO mice provide a powerful model to study the in vivo role of the P450 system in drug metabolism and efficacy, as well as in chemical toxicity.},
  language  = {en}
}
@article{KapelyukhHendersonScheeretal.2019,
  author    = {Kapelyukh, Yury and Henderson, Colin James and Scheer, Nico and Rode, Anja and Wolf, Charles Roland},
  title     = {Defining the contribution of CYP1A1 and CYP1A2 to drug metabolism using humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 KO mice},
  series = {Drug Metabolism and Disposition},
  journal   = {Drug Metabolism and Disposition},
  number    = {Early view},
  doi       = {10.1124/dmd.119.087718},
  pages     = {43 Seiten},
  year      = {2019},
  language  = {en}
}
@article{ScheerKapelyukhRodeetal.2015,
  author    = {Scheer, Nico and Kapelyukh, Yury and Rode, Anja and Oswald, Stefan and Busch, Diana and Mclaughlin, Lesley A. and Lin, De and Henderson, Colin J. and Wolf, C. Roland},
  title     = {Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model},
  series = {Drug Metabolism and Disposition},
  volume    = {43},
  journal   = {Drug Metabolism and Disposition},
  number    = {11},
  publisher = {ASPET},
  address   = {Bethesda},
  issn      = {1521-009x},
  doi       = {10.1124/dmd.115.065656},
  pages     = {1679 -- 1690},
  year      = {2015},
  language  = {en}
}
@article{FeuerriegelKloseSloboshaninetal.1994,
  author    = {Feuerriegel, Uwe and Klose, W. and Sloboshanin, S. and Goebel, H. [u.a.]},
  title     = {Deactivation of a palladium-supported alumina catalyst by hydrogen sulfide during the oxidation of methane},
  series = {Langmuir: the ACS journal of surfaces and colloids. 10 (1994), H. 10},
  journal   = {Langmuir: the ACS journal of surfaces and colloids. 10 (1994), H. 10},
  isbn      = {0743-74363},
  pages     = {3567 -- 3570},
  year      = {1994},
  language  = {en}
}
@article{FeuerriegelStahlberg1995,
  author    = {Feuerriegel, Uwe and Stahlberg, R.},
  title     = {Das Thermoselect-Verfahren zur Energie- und Rohstoffgewinnung - Konzepte, Verfahren, Kosten},
  series = {Thermische Abfallentsorgung - Konzepte, Kosten, Verfahren. Tagung Veitsh{\"o}chheim, 27./28.06.1995, VDI-Gesellschaft Energietechnik},
  journal   = {Thermische Abfallentsorgung - Konzepte, Kosten, Verfahren. Tagung Veitsh{\"o}chheim, 27./28.06.1995, VDI-Gesellschaft Energietechnik},
  publisher = {VDI-Verl.},
  address   = {D{\"u}sseldorf},
  isbn      = {0083-5560},
  pages     = {319 -- 319},
  year      = {1995},
  language  = {de}
}
@article{ElbersThomzik1990,
  author    = {Elbers, Gereon and Thomzik, Manfred},
  title     = {Das Entstehen geruchsintensiver schwefelhaltiger organischer Verbindungen in Lackierereien und M{\"o}glichkeiten zu deren Vermeidung},
  series = {Aus der T{\"a}tigkeit der LIS / Landesanstalt f{\"u}r Immissionsschutz des Landes Nordrhein-Westfalen. 1989 (1990)},
  journal   = {Aus der T{\"a}tigkeit der LIS / Landesanstalt f{\"u}r Immissionsschutz des Landes Nordrhein-Westfalen. 1989 (1990)},
  isbn      = {0931-5497},
  pages     = {35},
  year      = {1990},
  language  = {de}
}
@article{PinkenburgSchiffelsSelmer2016,
  author    = {Pinkenburg, Olaf and Schiffels, Johannes and Selmer, Thorsten},
  title     = {Das CoLibry-Konzept - ein Werkzeugkasten f{\"u}r die Synthetische Biologie: Bioproduktion},
  series = {BIOspektrum},
  volume    = {22},
  journal   = {BIOspektrum},
  number    = {6},
  publisher = {Springer},
  address   = {Berlin},
  doi       = {10.1007/s12268-016-0734-8},
  pages     = {593 -- 595},
  year      = {2016},
  abstract  = {Regardless of size or destination, synthetic biology starts with com-parably small information units, which need to be combined and properly arranged in order to achieve a certain goal. This may be the de novo synthesis of individual genes from oligonucleotides, a shuffling of protein domains in order to create novel biocatalysts, the assembly of multiple enzyme encoding genes in metabolic pathway design, or strain development at the production stage. The CoLibry concept has been designed in order to close the gap between recombinant production of individual genes and genome editing.},
  language  = {de}
}