@article{VahidpourGuthmanArreolaetal.2022, author = {Vahidpour, Farnoosh and Guthman, Eric and Arreola, Julia and Alghazali, Yousef H. M. and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {Assessment of Various Process Parameters for Optimized Sterilization Conditions Using a Multi-Sensing Platform}, series = {Foods}, volume = {11}, journal = {Foods}, number = {5}, publisher = {MDPI}, address = {Basel}, issn = {2304-8158}, doi = {10.3390/foods11050660}, pages = {Artikel 660}, year = {2022}, abstract = {In this study, an online multi-sensing platform was engineered to simultaneously evaluate various process parameters of food package sterilization using gaseous hydrogen peroxide (H₂O₂). The platform enabled the validation of critical aseptic parameters. In parallel, one series of microbiological count reduction tests was performed using highly resistant spores of B. atrophaeus DSM 675 to act as the reference method for sterility validation. By means of the multi-sensing platform together with microbiological tests, we examined sterilization process parameters to define the most effective conditions with regards to the highest spore kill rate necessary for aseptic packaging. As these parameters are mutually associated, a correlation between different factors was elaborated. The resulting correlation indicated the need for specific conditions regarding the applied H₂O₂ gas temperature, the gas flow and concentration, the relative humidity and the exposure time. Finally, the novel multi-sensing platform together with the mobile electronic readout setup allowed for the online and on-site monitoring of the sterilization process, selecting the best conditions for sterility and, at the same time, reducing the use of the time-consuming and costly microbiological tests that are currently used in the food package industry.}, language = {en} } @article{AngermannGuenthnerHanssenetal.2022, author = {Angermann, Susanne and G{\"u}nthner, Roman and Hanssen, Henner and Lorenz, Georg and Braunisch, Matthias C. and Steubl, Dominik and Matschkal, Julia and Kemmner, Stephan and Hausinger, Renate and Block, Zenonas and Haller, Bernhard and Heemann, Uwe and Kotliar, Konstantin and Grimmer, Timo and Schmaderer, Christoph}, title = {Cognitive impairment and microvascular function in end-stage renal disease}, series = {International Journal of Methods in Psychiatric Research (MPR)}, volume = {31}, journal = {International Journal of Methods in Psychiatric Research (MPR)}, number = {2}, publisher = {Wiley}, issn = {1049-8931 (Print)}, doi = {10.1002/mpr.1909}, pages = {1 -- 10}, year = {2022}, abstract = {Objective Hemodialysis patients show an approximately threefold higher prevalence of cognitive impairment compared to the age-matched general population. Impaired microcirculatory function is one of the assumed causes. Dynamic retinal vessel analysis is a quantitative method for measuring neurovascular coupling and microvascular endothelial function. We hypothesize that cognitive impairment is associated with altered microcirculation of retinal vessels. Methods 152 chronic hemodialysis patients underwent cognitive testing using the Montreal Cognitive Assessment. Retinal microcirculation was assessed by Dynamic Retinal Vessel Analysis, which carries out an examination recording retinal vessels' reaction to a flicker light stimulus under standardized conditions. Results In unadjusted as well as in adjusted linear regression analyses a significant association between the visuospatial executive function domain score of the Montreal Cognitive Assessment and the maximum arteriolar dilation as response of retinal arterioles to the flicker light stimulation was obtained. Conclusion This is the first study determining retinal microvascular function as surrogate for cerebral microvascular function and cognition in hemodialysis patients. The relationship between impairment in executive function and reduced arteriolar reaction to flicker light stimulation supports the involvement of cerebral small vessel disease as contributing factor for the development of cognitive impairment in this patient population and might be a target for noninvasive disease monitoring and therapeutic intervention.}, language = {en} } @article{RossiWinandsButenweg2022, author = {Rossi, Leonardo and Winands, Mark H. M. and Butenweg, Christoph}, title = {Monte Carlo Tree Search as an intelligent search tool in structural design problems}, series = {Engineering with Computers : An International Journal for Simulation-Based Engineering}, volume = {38}, journal = {Engineering with Computers : An International Journal for Simulation-Based Engineering}, number = {4}, editor = {Zhang, Jessica}, publisher = {Springer Nature}, address = {Cham}, issn = {1435-5663}, doi = {10.1007/s00366-021-01338-2}, pages = {3219 -- 3236}, year = {2022}, abstract = {Monte Carlo Tree Search (MCTS) is a search technique that in the last decade emerged as a major breakthrough for Artificial Intelligence applications regarding board- and video-games. In 2016, AlphaGo, an MCTS-based software agent, outperformed the human world champion of the board game Go. This game was for long considered almost infeasible for machines, due to its immense search space and the need for a long-term strategy. Since this historical success, MCTS is considered as an effective new approach for many other scientific and technical problems. Interestingly, civil structural engineering, as a discipline, offers many tasks whose solution may benefit from intelligent search and in particular from adopting MCTS as a search tool. In this work, we show how MCTS can be adapted to search for suitable solutions of a structural engineering design problem. The problem consists of choosing the load-bearing elements in a reference reinforced concrete structure, so to achieve a set of specific dynamic characteristics. In the paper, we report the results obtained by applying both a plain and a hybrid version of single-agent MCTS. The hybrid approach consists of an integration of both MCTS and classic Genetic Algorithm (GA), the latter also serving as a term of comparison for the results. The study's outcomes may open new perspectives for the adoption of MCTS as a design tool for civil engineers.}, language = {en} } @article{MarinkovićButenweg2022, author = {Marinković, Marko and Butenweg, Christoph}, title = {Experimental testing of decoupled masonry infills with steel anchors for out-of-plane support under combined in-plane and out-of-plane seismic loading}, series = {Construction and Building Materials}, volume = {318}, journal = {Construction and Building Materials}, number = {1}, editor = {Ford, Michael C.}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1879-0526}, doi = {10.1016/j.conbuildmat.2021.126041}, year = {2022}, abstract = {Because of simple construction process, high energy efficiency, significant fire resistance and excellent sound isolation, masonry infilled reinforced concrete (RC) frame structures are very popular in most of the countries in the world, as well as in seismic active areas. However, many RC frame structures with masonry infills were seriously damaged during earthquake events, as the traditional infills are generally constructed with direct contact to the RC frame which brings undesirable infill/frame interaction. This interaction leads to the activation of the equivalent diagonal strut in the infill panel, due to the RC frame deformation, and combined with seismically induced loads perpendicular to the infill panel often causes total collapses of the masonry infills and heavy damages to the RC frames. This fact was the motivation for developing different approaches for improving the behaviour of masonry infills, where infill isolation (decoupling) from the frame has been more intensively studied in the last decade. In-plane isolation of the infill wall reduces infill activation, but causes the need for additional measures to restrain out-of-plane movements. This can be provided by installing steel anchors, as proposed by some researchers. Within the framework of European research project INSYSME (Innovative Systems for Earthquake Resistant Masonry Enclosures in Reinforced Concrete Buildings) the system based on a use of elastomers for in-plane decoupling and steel anchors for out-of-plane restrain was tested. This constructive solution was tested and deeply investigated during the experimental campaign where traditional and decoupled masonry infilled RC frames with anchors were subjected to separate and combined in-plane ‬and out-of-plane loading. Based on a detailed evaluation and comparison of the test results, the performance and effectiveness of the developed system are illustrated.}, language = {en} } @article{FiedlerOrzadaFloeseretal.2022, author = {Fiedler, Thomas M. and Orzada, Stephan and Fl{\"o}ser, Martina and Rietsch, Stefan H. G. and Schmidt, Simon and Stelter, Jonathan K. and Wittrich, Marco and Quick, Harald H. and Bitz, Andreas and Ladd, Mark E.}, title = {Performance and safety assessment of an integrated transmitarray for body imaging at 7 T under consideration of specificabsorption rate, tissue temperature, and thermal dose}, series = {NMR in Biomedicine}, volume = {35}, journal = {NMR in Biomedicine}, number = {5}, publisher = {Wiley}, issn = {0952-3480 (Print)}, doi = {10.1002/nbm.4656}, pages = {1 -- 17}, year = {2022}, abstract = {In this study, the performance of an integrated body-imaging array for 7 T with 32 radiofrequency (RF) channels under consideration of local specific absorption rate (SAR), tissue temperature, and thermal dose limits was evaluated and the imaging performance was compared with a clinical 3 T body coil. Thirty-two transmit elements were placed in three rings between the bore liner and RF shield of the gradient coil. Slice-selective RF pulse optimizations for B1 shimming and spokes were performed for differently oriented slices in the body under consideration of realistic constraints for power and local SAR. To improve the B1+ homogeneity, safety assessments based on temperature and thermal dose were performed to possibly allow for higher input power for the pulse optimization than permissible with SAR limits. The results showed that using two spokes, the 7 T array outperformed the 3 T birdcage in all the considered regions of interest. However, a significantly higher SAR or lower duty cycle at 7 T is necessary in some cases to achieve similar B1+ homogeneity as at 3 T. The homogeneity in up to 50 cm-long coronal slices can particularly benefit from the high RF shim performance provided by the 32 RF channels. The thermal dose approach increases the allowable input power and the corresponding local SAR, in one example up to 100 W/kg, without limiting the exposure time necessary for an MR examination. In conclusion, the integrated antenna array at 7 T enables a clinical workflow for body imaging and comparable imaging performance to a conventional 3 T clinical body coil.}, language = {en} } @article{Timme2022, author = {Timme, Michael}, title = {Beweislast beim gutgl{\"a}ubigen Erwerb eines Kraftfahrzeugs ohne Erhalt der Zulassungsbescheinigung Teil II — Zugleich eine Besprechung von BGH, Urt. v. 23.9.2022 - V ZR 148/21, MDR 2022, 1542}, series = {Monatsschrift f{\"u}r Deutsches Recht}, volume = {77}, journal = {Monatsschrift f{\"u}r Deutsches Recht}, number = {1}, publisher = {Verlag Dr. Otto Schmidt}, address = {K{\"o}ln}, issn = {0340-1812}, doi = {doi.org/10.9785/mdtr-2023-770102}, pages = {r5 -- r7}, year = {2022}, abstract = {Im Handel mit Kraftfahrzeugen geh{\"o}ren Aspekte des gutgl{\"a}ubigen Erwerbs zu den beinahe allt{\"a}glichen Standardproblemen. Der BGH f{\"u}gt in seiner Entscheidung v. 23.9.2022-VZR148/21, MDR 2022, 1541 diesem im Detail breit gef{\"a}cherten Themenfeld einen weiteren Mosaikstein hinzu: Der Erwerber erhielt das verkaufte Kfz ohne {\"U}bergabe einer Zulassungsbescheinigung Teil II, behauptet aber, diese Bescheinigung sei dem vom ihm eingeschalteten Vermittler bei Erwerb (als F{\"a}lschung) vorgelegt worden. Tats{\"a}chlich befand sich das Original durchg{\"a}ngig beim wahren Eigent{\"u}mer, der nunmehr Herausgabe des Fahrzeugs verlangt. Der BGH sch{\"u}tzt in dieser Gestaltung im Ergebnis den Erwerber. Die Entscheidung ist in mehrfacher Hinsicht bemerkenswert.}, language = {de} } @article{MorandiButenwegBreisetal.2022, author = {Morandi, Paolo and Butenweg, Christoph and Breis, Khaled and Beyer, Katrin and Magenes, Guido}, title = {Latest findings on the behaviour factor q for the seismic design of URM buildings}, series = {Bulletin of Earthquake Engineering}, volume = {20}, journal = {Bulletin of Earthquake Engineering}, number = {11}, editor = {Ansal, Atilla}, publisher = {Springer Nature}, address = {Cham}, issn = {1573-1456}, doi = {10.1007/s10518-022-01419-7}, pages = {5797 -- 5848}, year = {2022}, abstract = {Recent earthquakes as the 2012 Emilia earthquake sequence showed that recently built unreinforced masonry (URM) buildings behaved much better than expected and sustained, despite the maximum PGA values ranged between 0.20-0.30 g, either minor damage or structural damage that is deemed repairable. Especially low-rise residential and commercial masonry buildings with a code-conforming seismic design and detailing behaved in general very well without substantial damages. The low damage grades of modern masonry buildings that was observed during this earthquake series highlighted again that codified design procedures based on linear analysis can be rather conservative. Although advances in simulation tools make nonlinear calculation methods more readily accessible to designers, linear analyses will still be the standard design method for years to come. The present paper aims to improve the linear seismic design method by providing a proper definition of the q-factor of URM buildings. These q-factors are derived for low-rise URM buildings with rigid diaphragms which represent recent construction practise in low to moderate seismic areas of Italy and Germany. The behaviour factor components for deformation and energy dissipation capacity and for overstrength due to the redistribution of forces are derived by means of pushover analyses. Furthermore, considerations on the behaviour factor component due to other sources of overstrength in masonry buildings are presented. As a result of the investigations, rationally based values of the behaviour factor q to be used in linear analyses in the range of 2.0-3.0 are proposed.}, language = {en} } @article{ButenwegMarinkovicPhlippetal.2022, author = {Butenweg, Christoph and Marinkovic, Marko and Phlipp, Michel and Lins, Robin and Renaut, Philipp}, title = {Isolierung und BIM-basiertes Bauwerksmonitoring des neuen Geb{\"a}udekomplexes f{\"u}r das BioSense-Institut in Novi Sad, Serbien}, series = {Bauingenieur}, volume = {97}, journal = {Bauingenieur}, number = {6}, editor = {Haghsheno, Shervin}, publisher = {VDI Fachmedien}, address = {D{\"u}sseldorf}, issn = {1436-4867}, doi = {10.37544/0005-6650-2022-06-28}, pages = {S3 -- S5}, year = {2022}, abstract = {Im Norden von Serbien erfolgt in Novi Sad der Neubau eines modernen Forschungsgeb{\"a}udes f{\"u}r das BioSense-Institut mit finanzieller Unterst{\"u}tzung durch die Eu-rop{\"a}ische Union. Der Geb{\"a}udeteil mit Laboren wird zum Schutz und zur Sicherstellung des reibungslosen Betriebs der sensiblen und kapitalintensiven technischen Einbauten mit ei-ner Erdbebenisolierung mit integrierter K{\"o}rperschallisolation versehen. Zus{\"a}tzlich wird der entkoppelte Laborteil des For-schungsgeb{\"a}udes mit einem BIM-basierten Bauwerksmonito-ring versehen, um {\"A}nderungen des Geb{\"a}udezustands jederzeit abfragen und beurteilen zu k{\"o}nnen.}, language = {de} } @misc{TopcuMadabhushiStaat2022, author = {Topcu, Murat and Madabhushi, Gopal Santana Phani and Staat, Manfred}, title = {Datasets from FEM Simulations done with COMSOL Multiphysics and Code_Aster}, doi = {10.6084/m9.figshare.19333295.v2}, year = {2022}, abstract = {Datasets from FEM Simulations done with COMSOL Multiphysics and Code_Aster for an elastic stress transfer between matrix and fibres having a variable radius.}, language = {en} } @article{KubalskiButenwegElDeib2022, author = {Kubalski, Thomas and Butenweg, Christoph and El-Deib, Khaled}, title = {Vereinfachte Ber{\"u}cksichtigung der Rahmentragwirkung in Mauerwerksgeb{\"a}uden}, series = {Bautechnik}, volume = {99}, journal = {Bautechnik}, number = {12}, editor = {Jesse, Dirk}, publisher = {Ernst \& Sohn}, address = {Berlin}, issn = {0932-8351}, doi = {10.1002/bate.202200081}, pages = {865 -- 928}, year = {2022}, abstract = {Aufgrund der gestiegenen Anforderungen durch h{\"o}here Ein-wirkungen aus Wind und Erdbeben ist eine Verbesserung und Optimierung der Berechnungs- und Bemessungsans{\"a}tze f{\"u}r Mauerwerksbauten erforderlich. Eine bessere Ausnutzung der Tragwerksreserven ist durch die Ber{\"u}cksichtigung der Rah-mentragwirkung mit einer Aktivierung der Deckenscheiben in den Rechenmodellen m{\"o}glich, die in der Praxis aufgrund der Komplexit{\"a}t der Wand-Decken-Interaktion bislang nicht aus-genutzt wird. Im vorliegenden Aufsatz wird ein vereinfachter Ansatz auf Grundlage der mitwirkenden Plattenbreite von Schubw{\"a}nden aus Mauerwerk vorgestellt, der die wesentli-chen Einfl ussfaktoren in parametrisierten Tabellen erfasst. Damit steht den Tragwerksplanern ein einfach anwendbares Werkzeug zur Verf{\"u}gung, um die Rahmentragwirkung in der Mauerwerksbemessung anzusetzen.}, language = {de} }